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Search results 1 to 100 out of 155 for Ttc21b

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Type Details Score
Gene
79809 | TTC21B
Type: gene
Organism: human
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Gene
740725 | TTC21B
Type: gene
Organism: chimpanzee
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Gene
527412 | TTC21B
Type: gene
Organism: cattle
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Gene
424176 | TTC21B
Type: gene
Organism: chicken
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Gene
569823 | ttc21b
Type: gene
Organism: zebrafish
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Gene
707811 | TTC21B
Type: gene
Organism: macaque, rhesus
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Gene
100490430 | ttc21b
Type: gene
Organism: frog, western clawed
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Gene
295654 | Ttc21b
Type: gene
Organism: rat
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Gene
608674 | TTC21B
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1920918 | Ttc21b
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100506134 | TTC21B-AS1
Type: gene
Organism: human
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Publication
31730647 | J:282171
First Author: Snedeker J
Year: 2019
Journal: PLoS Genet
Title: Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants.
Volume: 15
Issue: 11
Pages: e1008467
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Publication
29615573 | J:260676
 
First Author: Driver AM
Year: 2017
Journal: J Dev Biol
Title: Ttc21b Is Required in Bergmann Glia for Proper Granule Cell Radial Migration.
Volume: 5
Issue: 4
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Publication
19732765 | J:154376
First Author: Stottmann RW
Year: 2009
Journal: Dev Biol
Title: Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain.
Volume: 335
Issue: 1
Pages: 166-78
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Publication
- | J:265171
     
First Author: Zhang Z
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for plus-sized.
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Publication
27482817 | J:234171
First Author: Jacobs DT
Year: 2016
Journal: Dis Model Mech
Title: Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome.
Volume: 9
Issue: 7
Pages: 789-98
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Publication
33103996 | J:304031
   
First Author: Brooks ER
Year: 2020
Journal: Elife
Title: Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.
Volume: 9
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Publication
20889716 | J:164641
First Author: Mukhopadhyay S
Year: 2010
Journal: Genes Dev
Title: TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.
Volume: 24
Issue: 19
Pages: 2180-93
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Publication
28291836 | J:241366
First Author: Snedeker J
Year: 2017
Journal: PLoS One
Title: Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development.
Volume: 12
Issue: 3
Pages: e0173258
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Publication
28346501 | J:241357
First Author: Schock EN
Year: 2017
Journal: PLoS One
Title: A tissue-specific role for intraflagellar transport genes during craniofacial development.
Volume: 12
Issue: 3
Pages: e0174206
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Publication
18327258 | J:133725
First Author: Tran PV
Year: 2008
Journal: Nat Genet
Title: THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.
Volume: 40
Issue: 4
Pages: 403-410
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Protein Coding Gene
MGP_CAROLIEiJ_G0023605 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025759 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025515 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024979 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025588 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025619 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025047 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025056 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024527 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5603194
Age: embryonic day 9.5
Image: 2D middle
Specimen Label: 2D middle
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606915
Pattern: Diffuse
Stage: TS15
Assay Id: MGI:5603194
Age: embryonic day 9.5
Image: 2D middle
Note: Expression was diffuse in the axial ectoderm around the neural tube.
Specimen Label: 2D middle
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3275315
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5603194
Age: embryonic day 9.5
Image: 2D middle
Specimen Label: 2D middle
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647015
Pattern: Widespread
Stage: TS15
Assay Id: MGI:5603194
Age: embryonic day 9.5
Image: 2D middle
Note: Expression was widespread in the neural epithelium all along the anterior-posterior axis.
Specimen Label: 2D middle
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116913
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5603194
Age: embryonic day 8.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607313
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5603194
Age: embryonic day 8.5
Image: 2A
Note: Expression was detected in the anterior neural ectoderm.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5603194
Age: embryonic day 9.5
Image: 2C
Note: Expression was robust.
Specimen Label: 2C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5603184
Assay Type: RNA in situ
Annotation Date: 2014-10-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5603194
Age: embryonic day 9.5
Image: 2B
Note: Expression was robust.
Specimen Label: 2B
Detected: true
Specimen Num: 2
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Publication
31877115 | J:297904
 
First Author: Pottorf TS
Year: 2020
Journal: JCI Insight
Title: MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity.
Volume: 5
Issue: 2
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Publication
33683377 | J:315710
First Author: Allard BA
Year: 2021
Journal: Cell Mol Life Sci
Title: Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis.
Volume: 78
Issue: 7
Pages: 3743-3762
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Publication
35645293 | J:339134
 
First Author: Bumann EE
Year: 2022
Journal: J Dev Biol
Title: Genetic Interaction of Thm2 and Thm1 Shapes Postnatal Craniofacial Bone.
Volume: 10
Issue: 2
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Publication
32167205 | J:307178
First Author: Wang W
Year: 2020
Journal: FASEB J
Title: Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.
Volume: 34
Issue: 5
Pages: 6369-6381
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Publication
29463793 | J:262970
First Author: Idowu J
Year: 2018
Journal: Sci Rep
Title: Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease.
Volume: 8
Issue: 1
Pages: 3340
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Publication
22079090 | J:178620
First Author: Hong W
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Epigenetic involvement of Alien/ESET complex in thyroid hormone-mediated repression of E2F1 gene expression and cell proliferation.
Volume: 415
Issue: 4
Pages: 650-5
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Publication
17312020 | J:119719
First Author: Hou Y
Year: 2007
Journal: J Cell Biol
Title: Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.
Volume: 176
Issue: 5
Pages: 653-65
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Publication
27806291 | J:320053
First Author: Fu W
Year: 2016
Journal: Cell Rep
Title: Role for the IFT-A Complex in Selective Transport to the Primary Cilium.
Volume: 17
Issue: 6
Pages: 1505-1517
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Publication
24700869 | J:213263
First Author: Tran PV
Year: 2014
Journal: J Am Soc Nephrol
Title: Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models.
Volume: 25
Issue: 10
Pages: 2201-12
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Publication
11818962 | J:75360
First Author: Herron BJ
Year: 2002
Journal: Nat Genet
Title: Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.
Volume: 30
Issue: 2
Pages: 185-9
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Publication
19223390 | J:147584
First Author: Patterson VL
Year: 2009
Journal: Hum Mol Genet
Title: Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.
Volume: 18
Issue: 10
Pages: 1719-39
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
21258341 | -
First Author: Davis EE
Year: 2011
Journal: Nat Genet
Title: TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum.
Volume: 43
Issue: 3
Pages: 189-96
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DO Term
DOID:0110088 | asphyxiating thoracic dystrophy 4
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DO Term
DOID:0111119 | nephronophthisis 12
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Protein Domain
IPR040364 | TTC21A/TTC21B
Type: Family
Description: This entry includes tetratricopeptide repeat proteins 21A (TTC21A) and 21B (TTC21B), and other homologues with numerous tetratricopeptide repeats. TTC21B is a component of the IFT complex A (IFT-A), which is required for retrograde ciliary transport. Intraflagellar transport (IFT) is required for cilium assembly and trafficking within cilia []. Several diseases results from mutations in the TTC21B gene including nephronophthisis 12, short-rib thoracic dysplasia 4 with or without polydactyly, and Joubert syndrome 11 [].
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Allele
Ttc21b<m1Btlr> | MGI:6200040
Name: tetratricopeptide repeat domain 21B; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200041 | C57BL/6J-Ttc21b<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Ttc21b/Ttc21b
Background: C57BL/6J-Ttc21b
Zygosity: hm
Has Mutant Allele: true
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Protein Coding Gene
MGI:2135884 | Gpr63
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0025855 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028101 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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