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Search results 1 to 100 out of 757 for Ttk

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Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: zebrafish
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
First Author: Wu JH
Year: 2025
Journal: Adv Sci (Weinh)
Title: TTK Inhibition Alleviates Postinjury Neointimal Formation and Atherosclerosis.
Volume: 12
Issue: 6
Pages: e2409250
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GXD Expression  
Probe: MGI:7572386
Assay Type: RNA in situ
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Pattern: Widespread
Stage: TS16
Assay Id: MGI:7572401
Age: embryonic day 10.0
Note: Authors report that all candidate genes are broadly expressed in embryo.
Specimen Label: 3E Ttk
Detected: true
Specimen Num: 1
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Publication
First Author: Douville EM
Year: 1992
Journal: Mol Cell Biol
Title: Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.
Volume: 12
Issue: 6
Pages: 2681-9
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Publication
First Author: Fang Q
Year: 2021
Journal: Cell Death Dis
Title: The essential roles of Mps1 in spermatogenesis and fertility in mice.
Volume: 12
Issue: 6
Pages: 531
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Publication
First Author: Foijer F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.
Volume: 111
Issue: 37
Pages: 13427-32
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Publication
First Author: Lafirenze SJA
Year: 2026
Journal: Proc Natl Acad Sci U S A
Title: Non-cell-autonomous mechanisms of tumor initiation and relapse by chromosomal instability.
Volume: 123
Issue: 25
Pages: e2531095123
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication
First Author: Daniel J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.
Volume: 108
Issue: 13
Pages: 5384-9
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GXD Expression    
Probe: MGI:5792271
Assay Type: RT-PCR
Annotation Date: 2016-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5792280
Age: embryonic day 15.0
Image: 5
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression    
Probe: MGI:5792271
Assay Type: RT-PCR
Annotation Date: 2016-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5792280
Age: postnatal day 2
Image: 5
Specimen Label: P2
Detected: true
Specimen Num: 2
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GXD Expression    
Probe: MGI:5792271
Assay Type: RT-PCR
Annotation Date: 2016-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5792280
Age: postnatal day 7
Image: 5
Specimen Label: P7
Detected: true
Specimen Num: 3
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GXD Expression    
Probe: MGI:5792271
Assay Type: RT-PCR
Annotation Date: 2016-09-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5792280
Age: postnatal adult
Image: 5
Specimen Label: Adult
Detected: true
Specimen Num: 4
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GXD Expression  
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506804
Age: embryonic day 15.5
Note: Expression is seen in the uteric bud tips, as well as other non-uteric bud populations.
Specimen Label: 2 - Category 2
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6506804
Age: embryonic day 15.5
Note: Expression is seen in a non-tip population.
Specimen Label: 6 - Category B - E15.5
Detected: true
Specimen Num: 5
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GXD Expression  
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6506804
Age: embryonic day 12.5
Note: Expression is seen in a non-tip population.
Specimen Label: 6 - Category B - E12.5
Detected: true
Specimen Num: 6
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GXD Expression    
Probe: MGI:4425202
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540517
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6506804
Age: embryonic day 15.5
Note: There is a broad domain of tip expression.
Specimen Label: 3 - Class II
Detected: true
Specimen Num: 2
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GXD Expression    
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506804
Age: embryonic day 15.5
Specimen Label: 6 - Category B - E15.5
Detected: true
Specimen Num: 5
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GXD Expression    
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6506804
Age: embryonic day 12.5
Specimen Label: 5 - E12.5
Detected: true
Specimen Num: 3
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GXD Expression    
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506804
Age: embryonic day 15.5
Specimen Label: 5 - E15.5
Detected: true
Specimen Num: 4
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GXD Expression    
Probe: MGI:6506590
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506804
Age: embryonic day 15.5
Specimen Label: 2 - Category 2
Detected: true
Specimen Num: 1
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Publication  
First Author: Touati SA
Year: 2015
Journal: Nat Commun
Title: Mouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrest.
Volume: 6
Pages: 6946
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Publication
First Author: Hached K
Year: 2011
Journal: Development
Title: Mps1 at kinetochores is essential for female mouse meiosis I.
Volume: 138
Issue: 11
Pages: 2261-71
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Publication
First Author: Hoevenaar WHM
Year: 2020
Journal: Nat Commun
Title: Degree and site of chromosomal instability define its oncogenic potential.
Volume: 11
Issue: 1
Pages: 1501
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Publication
First Author: Schukken KM
Year: 2021
Journal: Sci Rep
Title: Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice.
Volume: 11
Issue: 1
Pages: 68
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Publication
First Author: El Yakoubi W
Year: 2017
Journal: Nat Commun
Title: Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I.
Volume: 8
Issue: 1
Pages: 694
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Publication  
First Author: Truong TTK
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Arl4c is involved in tooth germ development through osteoblastic/ameloblastic differentiation.
Volume: 679
Pages: 167-174
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Publication
First Author: Isokane M
Year: 2016
Journal: J Cell Biol
Title: ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.
Volume: 212
Issue: 6
Pages: 647-59
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Publication
First Author: Ekdahl Y
Year: 2012
Journal: Genome Res
Title: A-to-I editing of microRNAs in the mammalian brain increases during development.
Volume: 22
Issue: 8
Pages: 1477-87
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Publication
First Author: Zhou C
Year: 2020
Journal: Sci Adv
Title: The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I.
Volume: 6
Issue: 15
Pages: eaax3969
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Publication
First Author: Diril MK
Year: 2016
Journal: PLoS Genet
Title: Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint.
Volume: 12
Issue: 9
Pages: e1006310
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Publication
First Author: Evangelista M
Year: 2008
Journal: Sci Signal
Title: Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction.
Volume: 1
Issue: 39
Pages: ra7
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Publication
First Author: Hwang SY
Year: 2001
Journal: Mol Reprod Dev
Title: Expression of genes involved in mammalian meiosis during the transition from egg to embryo.
Volume: 59
Issue: 2
Pages: 144-58
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Publication
First Author: Li L
Year: 2023
Journal: Cell Rep
Title: Mettl14-mediated m(6)A modification ensures the cell-cycle progression of late-born retinal progenitor cells.
Volume: 42
Issue: 6
Pages: 112596
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Publication      
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
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Publication
First Author: Al Adhami H
Year: 2023
Journal: Nucleic Acids Res
Title: Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells.
Volume: 51
Issue: 7
Pages: 3130-3149
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Publication
First Author: Rutledge EA
Year: 2017
Journal: Development
Title: Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Volume: 144
Issue: 17
Pages: 3177-3188
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Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Author
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Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication      
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication        
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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