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Search results 1 to 100 out of 106 for Ttll6

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
284076 | TTLL6
Type: gene
Organism: human
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Gene
526482 | TTLL6
Type: gene
Organism: cattle
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Gene
431480 | TTLL6
Type: gene
Organism: chicken
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Gene
564075 | ttll6
Type: gene
Organism: zebrafish
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Gene
697698 | TTLL6
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR027754 | TTLL6
Type: Family
Description: TTLL6 is a polyglutamylase that preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step [, ]. It mediates tubulin polyglutamylation in cilia.
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Gene
287646 | Ttll6
Type: gene
Organism: rat
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Gene
480544 | TTLL6
Type: gene
Organism: dog, domestic
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Gene
468294 | TTLL6
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2683461 | Ttll6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
A4Q9E8
Organism: Mus musculus/domesticus
Length: 822  
Fragment?: false
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Publication
17499049 | J:130247
First Author: van Dijk J
Year: 2007
Journal: Mol Cell
Title: A targeted multienzyme mechanism for selective microtubule polyglutamylation.
Volume: 26
Issue: 3
Pages: 437-48
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Publication
21074048 | J:166837
First Author: Rogowski K
Year: 2010
Journal: Cell
Title: A family of protein-deglutamylating enzymes associated with neurodegeneration.
Volume: 143
Issue: 4
Pages: 564-78
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Protein
B9EJA6
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Publication
24065130 | J:202831
First Author: Zempel H
Year: 2013
Journal: EMBO J
Title: Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.
Volume: 32
Issue: 22
Pages: 2920-37
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Publication
32747782 | J:297726
First Author: Mahalingan KK
Year: 2020
Journal: Nat Struct Mol Biol
Title: Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Volume: 27
Issue: 9
Pages: 802-813
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Publication
20530212 | J:162689
First Author: Lacroix B
Year: 2010
Journal: J Cell Biol
Title: Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.
Volume: 189
Issue: 6
Pages: 945-54
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Publication
26829768 | J:231311
First Author: Xia P
Year: 2016
Journal: Nat Immunol
Title: Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.
Volume: 17
Issue: 4
Pages: 369-78
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Publication
23897886 | J:201638
First Author: Bosch Grau M
Year: 2013
Journal: J Cell Biol
Title: Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia.
Volume: 202
Issue: 3
Pages: 441-51
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Protein Coding Gene
MGP_CAROLIEiJ_G0017022 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018999 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2683461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018307 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018822 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019432 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018152 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017868 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7446625
Assay Type: RT-PCR
Annotation Date: 2023-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:7446654
Age: embryonic day 0.5
Image: S2
Specimen Label: 1 cell
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7446625
Assay Type: RT-PCR
Annotation Date: 2023-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Stage: TS03
Assay Id: MGI:7446654
Age: embryonic day 2.5
Image: S2
Specimen Label: 8 cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611814
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Specimen Label: E9.0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124313
Specimen Label: JAX_1124313
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124325
Note: kidney
Specimen Label: JAX_1124325
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124315
Specimen Label: JAX_1124315
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:2683722
Age: embryonic day 7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124321
Specimen Label: JAX_1124321
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1639914
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Specimen Label: E9.0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1653614
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Specimen Label: E9.0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124319
Specimen Label: JAX_1124319
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607212
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2683722
Age: embryonic day 7.75
Image: E7.75
Note: Expression is detected in the node.
Specimen Label: E7.75
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627214
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Specimen Label: E9.0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124327
Specimen Label: JAX_1124327
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619514
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Specimen Label: E9.0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7488401
Assay Type: RNA in situ
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7488419
Age: embryonic day 13.5
Image: S1A,B
Specimen Label: S1A,B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7488401
Assay Type: RNA in situ
Annotation Date: 2023-06-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1736421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7488419
Age: embryonic day 13.5
Image: S1C,D
Note: Expression increased compared to control.
Specimen Label: S1C,D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124317
Specimen Label: JAX_1124317
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692805
Age: postnatal adult
Image: JAX_1124311
Specimen Label: JAX_1124311
Detected: true
Specimen Num: 1
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Publication
15890843 | J:241131
First Author: Janke C
Year: 2005
Journal: Science
Title: Tubulin polyglutamylase enzymes are members of the TTL domain protein family.
Volume: 308
Issue: 5729
Pages: 1758-62
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Protein
A4Q9E8-2
Organism: Mus musculus/domesticus
Length: 718  
Fragment?: false
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Publication
28794449 | J:252746
First Author: Liu B
Year: 2017
Journal: Nat Commun
Title: IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.
Volume: 8
Issue: 1
Pages: 231
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Publication
36825984 | J:334018
 
First Author: Janečková E
Year: 2023
Journal: Development
Title: Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis.
Volume: 150
Issue: 5
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Publication
36043912 | J:330418
First Author: Zhu X
Year: 2022
Journal: Cancer Res
Title: Asialoglycoprotein Receptor 1 Functions as a Tumor Suppressor in Liver Cancer via Inhibition of STAT3.
Volume: 82
Issue: 21
Pages: 3987-4000
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Publication
29593216 | J:259707
First Author: Ye B
Year: 2018
Journal: Nat Commun
Title: Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.
Volume: 9
Issue: 1
Pages: 1261
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Publication
9806826 | J:51104
First Author: Mohlke KL
Year: 1998
Journal: Genomics
Title: Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level.
Volume: 54
Issue: 1
Pages: 19-30
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Publication
37890489 | J:343289
First Author: Ho KH
Year: 2023
Journal: Dev Cell
Title: Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.
Volume: 58
Issue: 23
Pages: 2641-2651.e6
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Publication
14613977 | J:85124
First Author: Sousa-Nunes R
Year: 2003
Journal: Genome Res
Title: Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.
Volume: 13
Issue: 12
Pages: 2609-20
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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