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Search results 1 to 82 out of 82 for Ttll6

0.021s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: TTLL6 is a polyglutamylase that preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step [, ]. It mediates tubulin polyglutamylation in cilia.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: van Dijk J
Year: 2007
Journal: Mol Cell
Title: A targeted multienzyme mechanism for selective microtubule polyglutamylation.
Volume: 26
Issue: 3
Pages: 437-48
Publication
First Author: Rogowski K
Year: 2010
Journal: Cell
Title: A family of protein-deglutamylating enzymes associated with neurodegeneration.
Volume: 143
Issue: 4
Pages: 564-78
Protein
Organism: Mus musculus
Length: 624  
Fragment?: false
Protein
Organism: Mus musculus
Length: 822  
Fragment?: false
Publication
First Author: Zempel H
Year: 2013
Journal: EMBO J
Title: Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.
Volume: 32
Issue: 22
Pages: 2920-37
Publication
First Author: Lacroix B
Year: 2010
Journal: J Cell Biol
Title: Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.
Volume: 189
Issue: 6
Pages: 945-54
Publication
First Author: Xia P
Year: 2016
Journal: Nat Immunol
Title: Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.
Volume: 17
Issue: 4
Pages: 369-78
Publication
First Author: Mahalingan KK
Year: 2020
Journal: Nat Struct Mol Biol
Title: Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Volume: 27
Issue: 9
Pages: 802-813
Publication
First Author: Bosch Grau M
Year: 2013
Journal: J Cell Biol
Title: Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia.
Volume: 202
Issue: 3
Pages: 441-51
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611814
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:2683722
Age: embryonic day 7.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1639914
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1653614
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607212
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:2683722
Age: embryonic day 7.75
Image: E7.75
Note: Expression is detected in the node.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627214
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:2683710
Assay Type: RNA in situ
Annotation Date: 2004-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619514
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:2683722
Age: embryonic day 9.0
Image: E9.0
Note: Expression is detected in the branchial arches and the otic vesicle.
Detected: true
Specimen Num: 3
Publication
First Author: Janke C
Year: 2005
Journal: Science
Title: Tubulin polyglutamylase enzymes are members of the TTL domain protein family.
Volume: 308
Issue: 5729
Pages: 1758-62
Publication
First Author: Liu B
Year: 2017
Journal: Nat Commun
Title: IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.
Volume: 8
Issue: 1
Pages: 231
Publication
First Author: Mohlke KL
Year: 1998
Journal: Genomics
Title: Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level.
Volume: 54
Issue: 1
Pages: 19-30
Publication
First Author: Ye B
Year: 2018
Journal: Nat Commun
Title: Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.
Volume: 9
Issue: 1
Pages: 1261
Publication
First Author: Sousa-Nunes R
Year: 2003
Journal: Genome Res
Title: Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.
Volume: 13
Issue: 12
Pages: 2609-20
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
UniProt Feature
Begin: 1
Description: Tubulin polyglutamylase TTLL6
Type: chain
End: 822
Protein
Organism: Mus musculus
Length: 718  
Fragment?: false
Publication
First Author: Lee JE
Year: 2012
Journal: Nat Genet
Title: CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium.
Volume: 44
Issue: 2
Pages: 193-9
Publication
First Author: Ye B
Year: 2014
Journal: J Exp Med
Title: Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation.
Volume: 211
Issue: 12
Pages: 2439-54
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112