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Search results 1 to 100 out of 146 for Ttn

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Category: Publication
Type Details Score
Publication
First Author: Liao D
Year: 2019
Journal: Sci Rep
Title: Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency.
Volume: 9
Issue: 1
Pages: 16330
Publication
First Author: Garvey SM
Year: 2002
Journal: Genomics
Title: The muscular dystrophy with myositis (mdm) mouse mutation disrupts a skeletal muscle-specific domain of titin.
Volume: 79
Issue: 2
Pages: 146-9
Publication
First Author: Gramlich M
Year: 2009
Journal: J Mol Cell Cardiol
Title: Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Volume: 47
Issue: 3
Pages: 352-8
Publication
First Author: Gramlich M
Year: 2015
Journal: EMBO Mol Med
Title: Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy.
Volume: 7
Issue: 5
Pages: 562-76
Publication
First Author: Müller-Seitz M
Year: 1993
Journal: Genomics
Title: Chromosomal localization of the mouse titin gene and its relation to "muscular dystrophy with myositis" and nebulin genes on chromosome 2.
Volume: 18
Issue: 3
Pages: 559-61
Publication
First Author: Huebsch KA
Year: 2005
Journal: Hum Mol Genet
Title: Mdm muscular dystrophy: interactions with calpain 3 and a novel functional role for titin's N2A domain.
Volume: 14
Issue: 19
Pages: 2801-11
Publication
First Author: Rossi E
Year: 1994
Journal: Genomics
Title: Order of six loci at 2q24-q31 and orientation of the HOXD locus.
Volume: 24
Issue: 1
Pages: 34-40
Publication
First Author: Trinick J
Year: 1999
Journal: Trends Cell Biol
Title: Titin: a molecular control freak.
Volume: 9
Issue: 10
Pages: 377-80
Publication
First Author: Suzuki M
Year: 2002
Journal: Circulation
Title: Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy.
Volume: 105
Issue: 15
Pages: 1824-9
Publication
First Author: Gotthardt M
Year: 2003
Journal: J Biol Chem
Title: Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
Volume: 278
Issue: 8
Pages: 6059-65
Publication
First Author: Granzier HL
Year: 2009
Journal: Circ Res
Title: Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.
Volume: 105
Issue: 6
Pages: 557-64
Publication
First Author: Lee EJ
Year: 2013
Journal: Arch Biochem Biophys
Title: Calcium sensitivity and myofilament lattice structure in titin N2B KO mice.
Volume: 535
Issue: 1
Pages: 76-83
Publication  
First Author: Slater RE
Year: 2017
Journal: J Mol Cell Cardiol
Title: Effect of exercise on passive myocardial stiffness in mice with diastolic dysfunction.
Volume: 108
Pages: 24-33
Publication
First Author: Elhamine F
Year: 2014
Journal: J Cell Sci
Title: Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kinetics.
Volume: 127
Issue: Pt 17
Pages: 3666-74
Publication
First Author: da Silva Lopes K
Year: 2011
Journal: J Cell Biol
Title: Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres.
Volume: 193
Issue: 4
Pages: 785-98
Publication
First Author: Chung CS
Year: 2013
Journal: Circulation
Title: Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction.
Volume: 128
Issue: 1
Pages: 19-28
Publication  
First Author: Hidalgo C
Year: 2014
Journal: Arch Biochem Biophys
Title: Effect of exercise training on post-translational and post-transcriptional regulation of titin stiffness in striated muscle of wild type and IG KO mice.
Volume: 552-553
Pages: 100-7
Publication
First Author: Tonino P
Year: 2017
Journal: Nat Commun
Title: The giant protein titin regulates the length of the striated muscle thick filament.
Volume: 8
Issue: 1
Pages: 1041
Publication  
First Author: Tonino P
Year: 2019
Journal: J Mol Cell Cardiol
Title: Fine mapping titin's C-zone: Matching cardiac myosin-binding protein C stripes with titin's super-repeats.
Volume: 133
Pages: 47-56
Publication    
First Author: Brynnel A
Year: 2018
Journal: Elife
Title: Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy.
Volume: 7
Publication      
First Author: May SR
Year: 2002
Journal: MGI Direct Data Submission
Title: Report of the shrunken-head phenotypic mutant
Publication  
First Author: Miyano CA
Year: 2019
Journal: J Exp Biol
Title: Severe thermoregulatory deficiencies in mice with a deletion in the titin gene TTN.
Volume: 222
Issue: Pt 9
Publication
First Author: Lopez MA
Year: 2008
Journal: Am J Physiol Cell Physiol
Title: Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model.
Volume: 295
Issue: 5
Pages: C1092-102
Publication  
First Author: Lane PW
Year: 1985
Journal: Mouse News Lett
Title: Muscular dystrophy with myositis (mdm)
Volume: 73
Pages: 18
Publication  
First Author: Tahir U
Year: 2020
Journal: J Exp Biol
Title: Effects of a titin mutation on force enhancement and force depression in mouse soleus muscles.
Volume: 223
Issue: Pt 2
Publication
First Author: Labeit S
Year: 1990
Journal: Nature
Title: A regular pattern of two types of 100-residue motif in the sequence of titin.
Volume: 345
Issue: 6272
Pages: 273-6
Publication
First Author: Fritz JD
Year: 1993
Journal: Comp Biochem Physiol B
Title: Characterization of a partial cDNA clone encoding porcine skeletal muscle titin: comparison with rabbit and mouse skeletal muscle titin sequences.
Volume: 105
Issue: 2
Pages: 357-60
Publication
First Author: Kolmerer B
Year: 1996
Journal: J Mol Biol
Title: Genomic organization of M line titin and its tissue-specific expression in two distinct isoforms.
Volume: 256
Issue: 3
Pages: 556-63
Publication
First Author: Musa H
Year: 2006
Journal: J Cell Sci
Title: Targeted homozygous deletion of M-band titin in cardiomyocytes prevents sarcomere formation.
Volume: 119
Issue: Pt 20
Pages: 4322-31
Publication
First Author: Xing XB
Year: 2011
Journal: Genomics
Title: The discovery of novel protein-coding features in mouse genome based on mass spectrometry data.
Volume: 98
Issue: 5
Pages: 343-51
Publication
First Author: Cadar AG
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Upstream open reading frame in 5'-untranslated region reduces titin mRNA translational efficiency.
Volume: 453
Issue: 1
Pages: 185-91
Publication
First Author: Rudolph F
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
Volume: 116
Issue: 50
Pages: 25126-25136
Publication
First Author: Radke MH
Year: 2019
Journal: Circulation
Title: Deleting Full Length Titin Versus the Titin M-Band Region Leads to Differential Mechanosignaling and Cardiac Phenotypes.
Volume: 139
Issue: 15
Pages: 1813-1827
Publication
First Author: Slater RE
Year: 2019
Journal: J Gen Physiol
Title: Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.
Volume: 151
Issue: 1
Pages: 42-52
Publication
First Author: Peng J
Year: 2007
Journal: Circulation
Title: Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region.
Volume: 115
Issue: 6
Pages: 743-51
Publication
First Author: Granzier HL
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.
Volume: 111
Issue: 40
Pages: 14589-94
Publication
First Author: Methawasin M
Year: 2014
Journal: Circulation
Title: Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.
Volume: 129
Issue: 19
Pages: 1924-36
Publication
First Author: Radke MH
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.
Volume: 104
Issue: 9
Pages: 3444-9
Publication  
First Author: Smart N
Year: 2017
Journal: J Mol Cell Cardiol
Title: Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice.
Volume: 102
Pages: 94-107
Publication
First Author: Gregorio CC
Year: 1998
Journal: J Cell Biol
Title: The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity.
Volume: 143
Issue: 4
Pages: 1013-27
Publication
First Author: Prudner BC
Year: 2014
Journal: FEBS Lett
Title: α-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin.
Volume: 588
Issue: 24
Pages: 4625-30
Publication
First Author: Bang ML
Year: 2001
Journal: Circ Res
Title: The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.
Volume: 89
Issue: 11
Pages: 1065-72
Publication  
First Author: Hidalgo CG
Year: 2013
Journal: J Mol Cell Cardiol
Title: The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.
Volume: 54
Pages: 90-7
Publication
First Author: Buck D
Year: 2014
Journal: J Gen Physiol
Title: Removal of immunoglobulin-like domains from titin's spring segment alters titin splicing in mouse skeletal muscle and causes myopathy.
Volume: 143
Issue: 2
Pages: 215-30
Publication
First Author: Hinze F
Year: 2016
Journal: J Mol Med (Berl)
Title: Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.
Volume: 94
Issue: 12
Pages: 1349-1358
Publication
First Author: Bull M
Year: 2016
Journal: Circ Res
Title: Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (TtnΔIAjxn).
Volume: 119
Issue: 6
Pages: 764-72
Publication
First Author: Charton K
Year: 2010
Journal: Hum Mol Genet
Title: Removal of the calpain 3 protease reverses the myopathology in a mouse model for titinopathies.
Volume: 19
Issue: 23
Pages: 4608-24
Publication
First Author: Charton K
Year: 2015
Journal: Hum Mol Genet
Title: CAPN3-mediated processing of C-terminal titin replaced by pathological cleavage in titinopathy.
Volume: 24
Issue: 13
Pages: 3718-31
Publication
First Author: Anderson J
Year: 2002
Journal: Pflugers Arch
Title: Passive stiffness changes in soleus muscles from desmin knockout mice are not due to titin modifications.
Volume: 444
Issue: 6
Pages: 771-6
Publication
First Author: Herasse M
Year: 1999
Journal: Mol Cell Biol
Title: Expression and functional characteristics of calpain 3 isoforms generated through tissue-specific transcriptional and posttranscriptional events.
Volume: 19
Issue: 6
Pages: 4047-55
Publication
First Author: White J
Year: 2014
Journal: Anat Rec (Hoboken)
Title: Localization of sarcomeric proteins during myofibril assembly in cultured mouse primary skeletal myotubes.
Volume: 297
Issue: 9
Pages: 1571-84
Publication
First Author: Jurecic R
Year: 1998
Journal: Anal Biochem
Title: Identification and cloning of differentially expressed genes by long-distance differential display.
Volume: 259
Issue: 2
Pages: 235-44
Publication
First Author: Mohamed JS
Year: 2013
Journal: J Biol Chem
Title: Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction.
Volume: 288
Issue: 34
Pages: 24560-8
Publication
First Author: Raskin A
Year: 2012
Journal: J Biol Chem
Title: A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.
Volume: 287
Issue: 35
Pages: 29273-84
Publication
First Author: Mearini G
Year: 2010
Journal: Cardiovasc Res
Title: Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
Volume: 85
Issue: 2
Pages: 357-66
Publication
First Author: Hamdani N
Year: 2013
Journal: Circ Res
Title: Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation.
Volume: 112
Issue: 4
Pages: 664-74
Publication
First Author: Fougerousse F
Year: 2000
Journal: Hum Mol Genet
Title: Human-mouse differences in the embryonic expression patterns of developmental control genes and disease genes.
Volume: 9
Issue: 2
Pages: 165-73
Publication
First Author: Laure L
Year: 2010
Journal: FEBS J
Title: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-κB pathway in skeletal muscle.
Volume: 277
Issue: 20
Pages: 4322-37
Publication
First Author: Voelkel T
Year: 2013
Journal: Biochim Biophys Acta
Title: Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.
Volume: 1833
Issue: 4
Pages: 812-22
Publication
First Author: Gautel M
Year: 1998
Journal: Circ Res
Title: Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle.
Volume: 82
Issue: 1
Pages: 124-9
Publication
First Author: McKeown CR
Year: 2014
Journal: Dev Dyn
Title: Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo.
Volume: 243
Issue: 6
Pages: 800-17
Publication  
First Author: Hu B
Year: 2016
Journal: Exp Neurol
Title: Myf5 and Myogenin in the development of thymic myoid cells - Implications for a murine in vivo model of myasthenia gravis.
Volume: 277
Pages: 76-85
Publication  
First Author: Wang LA
Year: 2018
Journal: Neuropharmacology
Title: Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice.
Volume: 133
Pages: 85-93
Publication
First Author: Seto JT
Year: 2011
Journal: Hum Mol Genet
Title: Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling.
Volume: 20
Issue: 15
Pages: 2914-27
Publication
First Author: May SR
Year: 2004
Journal: Dev Biol
Title: A Titin mutation defines roles for circulation in endothelial morphogenesis.
Volume: 270
Issue: 1
Pages: 31-46
Publication
First Author: Kramerova I
Year: 2004
Journal: Hum Mol Genet
Title: Null mutation of calpain 3 (p94) in mice causes abnormal sarcomere formation in vivo and in vitro.
Volume: 13
Issue: 13
Pages: 1373-88
Publication
First Author: Witt SH
Year: 2005
Journal: J Mol Biol
Title: MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination.
Volume: 350
Issue: 4
Pages: 713-22
Publication
First Author: Hayashi C
Year: 2008
Journal: J Biol Chem
Title: Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle.
Volume: 283
Issue: 21
Pages: 14801-14
Publication
First Author: Hirschy A
Year: 2006
Journal: Dev Biol
Title: Establishment of cardiac cytoarchitecture in the developing mouse heart.
Volume: 289
Issue: 2
Pages: 430-41
Publication
First Author: Schaart G
Year: 1989
Journal: Development
Title: Desmin and titin expression in early postimplantation mouse embryos.
Volume: 107
Issue: 3
Pages: 585-96
Publication
First Author: Braun A
Year: 2003
Journal: Exp Cell Res
Title: PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions.
Volume: 284
Issue: 2
Pages: 239-50
Publication
First Author: Taylor RG
Year: 1993
Journal: Genomics
Title: Identification of the mutation in murine histidinemia (his) and genetic mapping of the murine histidase locus (Hal) on chromosome 10.
Volume: 16
Issue: 1
Pages: 231-40
Publication
First Author: Whitman SA
Year: 2011
Journal: Circ Res
Title: Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle.
Volume: 109
Issue: 3
Pages: 262-71
Publication
First Author: Sedehizade F
Year: 1997
Journal: Muscle Nerve
Title: Expression of nerve-regulated genes in muscles of mouse mutants affected by spinal muscular atrophies and muscular dystrophies.
Volume: 20
Issue: 2
Pages: 186-94
Publication
First Author: Braun T
Year: 1994
Journal: Development
Title: MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice.
Volume: 120
Issue: 11
Pages: 3083-92
Publication
First Author: Kaul A
Year: 2000
Journal: Cell
Title: Myf-5 revisited: loss of early myotome formation does not lead to a rib phenotype in homozygous Myf-5 mutant mice.
Volume: 102
Issue: 1
Pages: 17-9
Publication
First Author: Pelikan RC
Year: 2013
Journal: J Cell Biochem
Title: Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling.
Volume: 114
Issue: 4
Pages: 796-807
Publication
First Author: Yakushiji-Kaminatsui N
Year: 2018
Journal: PLoS Biol
Title: Similarities and differences in the regulation of HoxD genes during chick and mouse limb development.
Volume: 16
Issue: 11
Pages: e3000004
Publication
First Author: Manso AM
Year: 2013
Journal: J Biol Chem
Title: Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.
Volume: 288
Issue: 6
Pages: 4252-64
Publication
First Author: Witt CC
Year: 2004
Journal: J Mol Biol
Title: Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.
Volume: 336
Issue: 1
Pages: 145-54
Publication
First Author: Bennett PM
Year: 2006
Journal: Mol Biol Cell
Title: The transitional junction: a new functional subcellular domain at the intercalated disc.
Volume: 17
Issue: 4
Pages: 2091-100
Publication
First Author: Buckle VJ
Year: 1990
Journal: Hum Genet
Title: Localisation of a dystrophin-related autosomal gene to 6q24 in man, and to mouse chromosome 10 in the region of the dystrophia muscularis (dy) locus.
Volume: 85
Issue: 3
Pages: 324-6
Publication
First Author: Barbosky L
Year: 2006
Journal: Dev Dyn
Title: Apoptosis in the developing mouse heart.
Volume: 235
Issue: 9
Pages: 2592-602
Publication
First Author: Braun T
Year: 1995
Journal: EMBO J
Title: Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development.
Volume: 14
Issue: 6
Pages: 1176-86
Publication
First Author: Mohamed JS
Year: 2010
Journal: FASEB J
Title: Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch.
Volume: 24
Issue: 9
Pages: 3330-40
Publication
First Author: Chamberlain CM
Year: 2012
Journal: Hum Mol Genet
Title: Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise.
Volume: 21
Issue: 21
Pages: 4645-54
Publication
First Author: Schiaffino S
Year: 1996
Journal: Physiol Rev
Title: Molecular diversity of myofibrillar proteins: gene regulation and functional significance.
Volume: 76
Issue: 2
Pages: 371-423
Publication
First Author: Weinert S
Year: 2006
Journal: J Cell Biol
Title: M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere.
Volume: 173
Issue: 4
Pages: 559-70
Publication
First Author: Ye J
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.
Volume: 112
Issue: 23
Pages: E3020-9
Publication
First Author: Krishnan J
Year: 2008
Journal: Circ Res
Title: Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function.
Volume: 103
Issue: 10
Pages: 1139-46
Publication
First Author: Lin X
Year: 2006
Journal: Hum Mol Genet
Title: Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.
Volume: 15
Issue: 13
Pages: 2087-97
Publication
First Author: Lewandowski SL
Year: 2014
Journal: Hum Mol Genet
Title: Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.
Volume: 23
Issue: 14
Pages: 3801-9
Publication
First Author: de Groot NE
Year: 2020
Journal: Sci Rep
Title: Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function.
Volume: 10
Issue: 1
Pages: 7687
Publication
First Author: Wu T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: HSPB7 is indispensable for heart development by modulating actin filament assembly.
Volume: 114
Issue: 45
Pages: 11956-11961
Publication
First Author: Bang ML
Year: 2017
Journal: J Cell Physiol
Title: Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins.
Volume: 232
Issue: 1
Pages: 38-52
Publication
First Author: Nguyen AT
Year: 2011
Journal: Genes Dev
Title: DOT1L regulates dystrophin expression and is critical for cardiac function.
Volume: 25
Issue: 3
Pages: 263-74
Publication
First Author: Risebro CA
Year: 2009
Journal: Development
Title: Prox1 maintains muscle structure and growth in the developing heart.
Volume: 136
Issue: 3
Pages: 495-505
Publication
First Author: Davie JK
Year: 2007
Journal: Dev Biol
Title: Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle.
Volume: 311
Issue: 2
Pages: 650-64
Publication  
First Author: Funato N
Year: 2018
Journal: Arch Oral Biol
Title: Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans.
Volume: 95
Pages: 149-155
Publication
First Author: Bolt CC
Year: 2016
Journal: PLoS One
Title: Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.
Volume: 11
Issue: 4
Pages: e0154413