|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 385 for Txnip

<< First    < Previous  |  Next >    Last >>
0.038s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825681
Age: embryonic day 14.5
Image: Additional file 4 Txnip
Detected: true
Specimen Num: 1
Publication
First Author: Chen J
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Volume: 311
Issue: 1
Pages: H64-75
Publication
First Author: Hui ST
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Txnip balances metabolic and growth signaling via PTEN disulfide reduction.
Volume: 105
Issue: 10
Pages: 3921-6
Publication
First Author: Blouet C
Year: 2011
Journal: J Neurosci
Title: Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice.
Volume: 31
Issue: 16
Pages: 6019-27
Publication
First Author: Blouet C
Year: 2012
Journal: J Neurosci
Title: TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity.
Volume: 32
Issue: 29
Pages: 9870-7
Publication
First Author: Hand LE
Year: 2013
Journal: Endocrinology
Title: Induction of the metabolic regulator Txnip in fasting-induced and natural torpor.
Volume: 154
Issue: 6
Pages: 2081-91
Publication
First Author: Park YJ
Year: 2013
Journal: PLoS Pathog
Title: TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.
Volume: 9
Issue: 10
Pages: e1003646
Publication  
First Author: Tseng PC
Year: 2019
Journal: Front Immunol
Title: HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection.
Volume: 10
Pages: 2147
Publication
First Author: Muri J
Year: 2021
Journal: Eur J Immunol
Title: The thioredoxin-1 inhibitor Txnip restrains effector T-cell and germinal center B-cell expansion.
Volume: 51
Issue: 1
Pages: 115-124
Publication
First Author: Huy H
Year: 2018
Journal: Aging Cell
Title: TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress.
Volume: 17
Issue: 6
Pages: e12836
Publication
First Author: Chen J
Year: 2010
Journal: Diabetes
Title: Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.
Volume: 59
Issue: 2
Pages: 440-7
Publication
First Author: Chutkow WA
Year: 2010
Journal: Diabetes
Title: Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity.
Volume: 59
Issue: 6
Pages: 1424-34
Publication
First Author: Jung H
Year: 2013
Journal: Cell Metab
Title: TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress.
Volume: 18
Issue: 1
Pages: 75-85
Publication
First Author: Waldhart AN
Year: 2017
Journal: Cell Rep
Title: Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin.
Volume: 19
Issue: 10
Pages: 2005-2013
Publication
First Author: Qin K
Year: 2018
Journal: Diabetologia
Title: SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Volume: 61
Issue: 4
Pages: 906-918
Publication    
First Author: Beg M
Year: 2021
Journal: J Biol Chem
Title: ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes.
Pages: 100332
Publication
First Author: Thielen LA
Year: 2020
Journal: Cell Metab
Title: Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action.
Volume: 32
Issue: 3
Pages: 353-365.e8
Protein
Organism: Mus musculus
Length: 400  
Fragment?: false
Publication
First Author: Andres AM
Year: 2011
Journal: FEBS Lett
Title: Diminished AMPK signaling response to fasting in thioredoxin-interacting protein knockout mice.
Volume: 585
Issue: 8
Pages: 1223-30
Publication
First Author: Shi Y
Year: 2011
Journal: FEBS Lett
Title: Knockdown of thioredoxin interacting protein attenuates high glucose-induced apoptosis and activation of ASK1 in mouse mesangial cells.
Volume: 585
Issue: 12
Pages: 1789-95
Publication
First Author: Ren Y
Year: 2010
Journal: FEBS Lett
Title: p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells.
Volume: 584
Issue: 15
Pages: 3480-5
Publication
First Author: Jeong M
Year: 2009
Journal: J Immunol
Title: Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions.
Volume: 183
Issue: 4
Pages: 2495-505
Publication
First Author: Oslowski CM
Year: 2012
Journal: Cell Metab
Title: Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome.
Volume: 16
Issue: 2
Pages: 265-73
Publication  
First Author: Jung H
Year: 2016
Journal: Nat Commun
Title: Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity.
Volume: 7
Pages: 13674
Publication
First Author: Chutkow WA
Year: 2008
Journal: J Biol Chem
Title: Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production.
Volume: 283
Issue: 4
Pages: 2397-406
Publication
First Author: Lee S
Year: 2014
Journal: EMBO Mol Med
Title: Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress.
Volume: 6
Issue: 6
Pages: 732-43
Publication
First Author: Bedarida T
Year: 2018
Journal: FASEB J
Title: Reduced endothelial thioredoxin-interacting protein protects arteries from damage induced by metabolic stress in vivo.
Volume: 32
Issue: 6
Pages: 3108-3118
Publication
First Author: Domingues A
Year: 2020
Journal: Angiogenesis
Title: Targeting endothelial thioredoxin-interacting protein (TXNIP) protects from metabolic disorder-related impairment of vascular function and post-ischemic revascularisation.
Volume: 23
Issue: 2
Pages: 249-264
Publication
First Author: DeBalsi KL
Year: 2014
Journal: J Biol Chem
Title: Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle.
Volume: 289
Issue: 12
Pages: 8106-20
Publication
First Author: Hui TY
Year: 2004
Journal: J Biol Chem
Title: Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals.
Volume: 279
Issue: 23
Pages: 24387-93
Publication
First Author: Sheth SS
Year: 2005
Journal: J Lipid Res
Title: Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition.
Volume: 46
Issue: 1
Pages: 123-34
Publication
First Author: Sheth SS
Year: 2006
Journal: Oncogene
Title: Hepatocellular carcinoma in Txnip-deficient mice.
Volume: 25
Issue: 25
Pages: 3528-36
Publication
First Author: Nishizawa K
Year: 2011
Journal: Carcinogenesis
Title: Thioredoxin-interacting protein suppresses bladder carcinogenesis.
Volume: 32
Issue: 10
Pages: 1459-66
Publication
First Author: Gasiorek JJ
Year: 2015
Journal: Exp Hematol
Title: Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors.
Volume: 43
Issue: 5
Pages: 393-403.e2
Publication  
First Author: Yoon SJ
Year: 2019
Journal: Front Immunol
Title: Thioredoxin-Interacting Protein Promotes Phagosomal Acidification Upon Exposure to Escherichia coli Through Inflammasome-Mediated Caspase-1 Activation in Macrophages.
Volume: 10
Pages: 2636
Publication
First Author: Lee SY
Year: 2013
Journal: PLoS One
Title: Thioredoxin-interacting protein regulates glucose metabolism and affects cytoplasmic streaming in mouse oocytes.
Volume: 8
Issue: 8
Pages: e70708
Publication  
First Author: Mohamed IN
Year: 2020
Journal: Int J Mol Sci
Title: Deletion of Thioredoxin-Interacting Protein (TXNIP) Abrogates High Fat Diet-induced Retinal Leukostasis, Barrier Dysfunction and Microvascular Degeneration in a Mouse Obesity Model.
Volume: 21
Issue: 11
Publication  
First Author: Qiao S
Year: 2015
Journal: Nat Commun
Title: A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.
Volume: 6
Pages: 7014
Publication
First Author: Spindel ON
Year: 2014
Journal: Circ Res
Title: Thioredoxin-interacting protein is a biomechanical regulator of Src activity: key role in endothelial cell stress fiber formation.
Volume: 114
Issue: 7
Pages: 1125-32
Publication
First Author: Masson E
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.
Volume: 296
Issue: 6
Pages: E1251-61
Publication
First Author: Abdelsaid MA
Year: 2014
Journal: PLoS One
Title: Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy.
Volume: 9
Issue: 10
Pages: e110388
Publication
First Author: Zhou R
Year: 2010
Journal: Nat Immunol
Title: Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
Volume: 11
Issue: 2
Pages: 136-40
Publication    
First Author: Muri J
Year: 2020
Journal: Elife
Title: Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip.
Volume: 9
Publication
First Author: Lerner AG
Year: 2012
Journal: Cell Metab
Title: IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Volume: 16
Issue: 2
Pages: 250-64
Publication    
First Author: Dotimas JR
Year: 2016
Journal: Elife
Title: Diabetes regulates fructose absorption through thioredoxin-interacting protein.
Volume: 5
Publication
First Author: Zervou S
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis.
Volume: 305
Issue: 2
Pages: E263-70
Publication
First Author: Wang XQ
Year: 2012
Journal: Circ Res
Title: Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2.
Volume: 110
Issue: 4
Pages: 560-8
Publication
First Author: Jo S
Year: 2018
Journal: Diabetes
Title: miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function.
Volume: 67
Issue: 2
Pages: 256-264
Publication
First Author: Xu G
Year: 2013
Journal: Nat Med
Title: Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.
Volume: 19
Issue: 9
Pages: 1141-6
Publication
First Author: Yoshioka J
Year: 2007
Journal: Circ Res
Title: Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload.
Volume: 101
Issue: 12
Pages: 1328-38
Publication
First Author: Yoshioka J
Year: 2012
Journal: J Clin Invest
Title: Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.
Volume: 122
Issue: 1
Pages: 267-79
Publication
First Author: Myers RB
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart.
Volume: 310
Issue: 11
Pages: H1748-59
Publication
First Author: Papadia S
Year: 2008
Journal: Nat Neurosci
Title: Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Volume: 11
Issue: 4
Pages: 476-87
Publication
First Author: Chen J
Year: 2008
Journal: Diabetes
Title: Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.
Volume: 57
Issue: 4
Pages: 938-44
Publication
First Author: Filios SR
Year: 2014
Journal: J Biol Chem
Title: MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.
Volume: 289
Issue: 52
Pages: 36275-83
Publication
First Author: Chen J
Year: 2008
Journal: FASEB J
Title: Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.
Volume: 22
Issue: 10
Pages: 3581-94
Publication
First Author: He K
Year: 2017
Journal: Oncotarget
Title: Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development.
Volume: 8
Issue: 23
Pages: 37657-37672
Publication
First Author: Abais JM
Year: 2014
Journal: J Biol Chem
Title: Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia.
Volume: 289
Issue: 39
Pages: 27159-68
Publication
First Author: Panse M
Year: 2018
Journal: PLoS One
Title: Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms.
Volume: 13
Issue: 5
Pages: e0198016
Publication
First Author: Patwari P
Year: 2006
Journal: J Biol Chem
Title: The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.
Volume: 281
Issue: 31
Pages: 21884-91
Publication
First Author: Jing G
Year: 2014
Journal: J Biol Chem
Title: Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.
Volume: 289
Issue: 17
Pages: 11807-15
Publication
First Author: Park MJ
Year: 2014
Journal: J Hepatol
Title: Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo.
Volume: 61
Issue: 5
Pages: 1151-7
Publication
First Author: Bodnar JS
Year: 2002
Journal: Nat Genet
Title: Positional cloning of the combined hyperlipidemia gene Hyplip1.
Volume: 30
Issue: 1
Pages: 110-6
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ludwig DL
Year: 2001
Journal: Gene
Title: Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene.
Volume: 269
Issue: 1-2
Pages: 103-12
Publication
First Author: Lee KN
Year: 2005
Journal: Immunity
Title: VDUP1 is required for the development of natural killer cells.
Volume: 22
Issue: 2
Pages: 195-208
Publication
First Author: Donnelly KL
Year: 2004
Journal: J Nutr
Title: Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice.
Volume: 134
Issue: 6
Pages: 1475-80
Publication
First Author: Oka S
Year: 2006
Journal: FASEB J
Title: Impaired fatty acid utilization in thioredoxin binding protein-2 (TBP-2)-deficient mice: a unique animal model of Reye syndrome.
Volume: 20
Issue: 1
Pages: 121-3
Publication
First Author: Son A
Year: 2008
Journal: Eur J Immunol
Title: Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
Volume: 38
Issue: 5
Pages: 1358-67
Publication
First Author: Piao ZH
Year: 2012
Journal: Cell Immunol
Title: VDUP1 exacerbates bacteremic shock in mice infected with Pseudomonas aeruginosa.
Volume: 280
Issue: 1
Pages: 1-9
GXD Expression      
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1716122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312646
Note: kidney
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691606
Age: postnatal adult
Image: MRC Harwell_1312660
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3821058
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421757
Age: embryonic day 14.5
Image: DC32; Specimen C1379
Detected: true
Specimen Num: 1