| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3821058 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-15 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3564522 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3825681 |
| Age: |
embryonic day 14.5 |
| Image: |
Additional file 4 Txnip |
|
| Specimen Label: |
Additional file 4 Txnip |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakayama Y |
| Year: |
2021 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Txnip C247S mutation protects the heart against acute myocardial infarction. |
| Volume: |
155 |
|
| Pages: |
36-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2016 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling. |
| Volume: |
311 |
| Issue: |
1 |
| Pages: |
H64-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hui ST |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Txnip balances metabolic and growth signaling via PTEN disulfide reduction. |
| Volume: |
105 |
| Issue: |
10 |
| Pages: |
3921-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blouet C |
| Year: |
2011 |
| Journal: |
J Neurosci |
| Title: |
Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice. |
| Volume: |
31 |
| Issue: |
16 |
| Pages: |
6019-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blouet C |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity. |
| Volume: |
32 |
| Issue: |
29 |
| Pages: |
9870-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hand LE |
| Year: |
2013 |
| Journal: |
Endocrinology |
| Title: |
Induction of the metabolic regulator Txnip in fasting-induced and natural torpor. |
| Volume: |
154 |
| Issue: |
6 |
| Pages: |
2081-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muri J |
| Year: |
2021 |
| Journal: |
Eur J Immunol |
| Title: |
The thioredoxin-1 inhibitor Txnip restrains effector T-cell and germinal center B-cell expansion. |
| Volume: |
51 |
| Issue: |
1 |
| Pages: |
115-124 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park YJ |
| Year: |
2013 |
| Journal: |
PLoS Pathog |
| Title: |
TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
e1003646 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tseng PC |
| Year: |
2019 |
| Journal: |
Front Immunol |
| Title: |
HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection. |
| Volume: |
10 |
|
| Pages: |
2147 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huy H |
| Year: |
2018 |
| Journal: |
Aging Cell |
| Title: |
TXNIP regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress. |
| Volume: |
17 |
| Issue: |
6 |
| Pages: |
e12836 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death. |
| Volume: |
59 |
| Issue: |
2 |
| Pages: |
440-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chutkow WA |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
Deletion of the alpha-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity. |
| Volume: |
59 |
| Issue: |
6 |
| Pages: |
1424-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mukai N |
| Year: |
2021 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Cardiomyocyte-specific Txnip C247S mutation improves left ventricular functional reserve in streptozotocin-induced diabetic mice. |
| Volume: |
321 |
| Issue: |
2 |
| Pages: |
H259-H274 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jung H |
| Year: |
2013 |
| Journal: |
Cell Metab |
| Title: |
TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
75-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waldhart AN |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin. |
| Volume: |
19 |
| Issue: |
10 |
| Pages: |
2005-2013 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jung E |
| Year: |
2024 |
| Journal: |
Int J Biol Sci |
| Title: |
TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production. |
| Volume: |
20 |
| Issue: |
2 |
| Pages: |
606-620 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tian D |
| Year: |
2017 |
| Journal: |
Free Radic Biol Med |
| Title: |
Endogenous hydrogen sulfide-mediated MAPK inhibition preserves endothelial function through TXNIP signaling. |
| Volume: |
110 |
|
| Pages: |
291-299 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qin K |
| Year: |
2018 |
| Journal: |
Diabetologia |
| Title: |
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice. |
| Volume: |
61 |
| Issue: |
4 |
| Pages: |
906-918 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Beg M |
| Year: |
2021 |
| Journal: |
J Biol Chem |
| Title: |
ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes. |
|
|
| Pages: |
100332 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thielen LA |
| Year: |
2020 |
| Journal: |
Cell Metab |
| Title: |
Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. |
| Volume: |
32 |
| Issue: |
3 |
| Pages: |
353-365.e8 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
400
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Andres AM |
| Year: |
2011 |
| Journal: |
FEBS Lett |
| Title: |
Diminished AMPK signaling response to fasting in thioredoxin-interacting protein knockout mice. |
| Volume: |
585 |
| Issue: |
8 |
| Pages: |
1223-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shi Y |
| Year: |
2011 |
| Journal: |
FEBS Lett |
| Title: |
Knockdown of thioredoxin interacting protein attenuates high glucose-induced apoptosis and activation of ASK1 in mouse mesangial cells. |
| Volume: |
585 |
| Issue: |
12 |
| Pages: |
1789-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waldhart AN |
| Year: |
2023 |
| Journal: |
iScience |
| Title: |
Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP. |
| Volume: |
26 |
| Issue: |
5 |
| Pages: |
106538 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waldhart AN |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue. |
| Volume: |
36 |
| Issue: |
5 |
| Pages: |
109488 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeong M |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions. |
| Volume: |
183 |
| Issue: |
4 |
| Pages: |
2495-505 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Avequin T |
| Year: |
2023 |
| Journal: |
iScience |
| Title: |
Differential effects of sugar and fat on adipose tissue inflammation. |
| Volume: |
26 |
| Issue: |
7 |
| Pages: |
107163 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shah A |
| Year: |
2020 |
| Journal: |
iScience |
| Title: |
Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption. |
| Volume: |
23 |
| Issue: |
9 |
| Pages: |
101521 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oslowski CM |
| Year: |
2012 |
| Journal: |
Cell Metab |
| Title: |
Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
265-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ren Y |
| Year: |
2010 |
| Journal: |
FEBS Lett |
| Title: |
p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells. |
| Volume: |
584 |
| Issue: |
15 |
| Pages: |
3480-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee S |
| Year: |
2014 |
| Journal: |
EMBO Mol Med |
| Title: |
Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
732-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chutkow WA |
| Year: |
2008 |
| Journal: |
J Biol Chem |
| Title: |
Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production. |
| Volume: |
283 |
| Issue: |
4 |
| Pages: |
2397-406 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hui TY |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. |
| Volume: |
279 |
| Issue: |
23 |
| Pages: |
24387-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sheth SS |
| Year: |
2006 |
| Journal: |
Oncogene |
| Title: |
Hepatocellular carcinoma in Txnip-deficient mice. |
| Volume: |
25 |
| Issue: |
25 |
| Pages: |
3528-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sheth SS |
| Year: |
2005 |
| Journal: |
J Lipid Res |
| Title: |
Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition. |
| Volume: |
46 |
| Issue: |
1 |
| Pages: |
123-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rodriguez YA |
| Year: |
2021 |
| Journal: |
ACS Chem Neurosci |
| Title: |
Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons. |
| Volume: |
12 |
| Issue: |
16 |
| Pages: |
3049-3059 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoon SJ |
| Year: |
2019 |
| Journal: |
Front Immunol |
| Title: |
Thioredoxin-Interacting Protein Promotes Phagosomal Acidification Upon Exposure to Escherichia coli Through Inflammasome-Mediated Caspase-1 Activation in Macrophages. |
| Volume: |
10 |
|
| Pages: |
2636 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishizawa K |
| Year: |
2011 |
| Journal: |
Carcinogenesis |
| Title: |
Thioredoxin-interacting protein suppresses bladder carcinogenesis. |
| Volume: |
32 |
| Issue: |
10 |
| Pages: |
1459-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bedarida T |
| Year: |
2018 |
| Journal: |
FASEB J |
| Title: |
Reduced endothelial thioredoxin-interacting protein protects arteries from damage induced by metabolic stress in vivo. |
| Volume: |
32 |
| Issue: |
6 |
| Pages: |
3108-3118 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Domingues A |
| Year: |
2020 |
| Journal: |
Angiogenesis |
| Title: |
Targeting endothelial thioredoxin-interacting protein (TXNIP) protects from metabolic disorder-related impairment of vascular function and post-ischemic revascularisation. |
| Volume: |
23 |
| Issue: |
2 |
| Pages: |
249-264 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
DeBalsi KL |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle. |
| Volume: |
289 |
| Issue: |
12 |
| Pages: |
8106-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gasiorek JJ |
| Year: |
2015 |
| Journal: |
Exp Hematol |
| Title: |
Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors. |
| Volume: |
43 |
| Issue: |
5 |
| Pages: |
393-403.e2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mohamed IN |
| Year: |
2020 |
| Journal: |
Int J Mol Sci |
| Title: |
Deletion of Thioredoxin-Interacting Protein (TXNIP) Abrogates High Fat Diet-induced Retinal Leukostasis, Barrier Dysfunction and Microvascular Degeneration in a Mouse Obesity Model. |
| Volume: |
21 |
| Issue: |
11 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng W |
| Year: |
2020 |
| Journal: |
Endocrine |
| Title: |
Thioredoxin-interacting protein: a critical link between autophagy disorders and pancreatic β-cell dysfunction. |
| Volume: |
70 |
| Issue: |
3 |
| Pages: |
526-537 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SY |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Thioredoxin-interacting protein regulates glucose metabolism and affects cytoplasmic streaming in mouse oocytes. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
e70708 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu M |
| Year: |
2018 |
| Journal: |
Lab Invest |
| Title: |
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction. |
| Volume: |
98 |
| Issue: |
9 |
| Pages: |
1211-1224 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim S |
| Year: |
2024 |
| Journal: |
PLoS One |
| Title: |
TXNIP-mediated crosstalk between oxidative stress and glucose metabolism. |
| Volume: |
19 |
| Issue: |
2 |
| Pages: |
e0292655 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jung H |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity. |
| Volume: |
7 |
|
| Pages: |
13674 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qiao S |
| Year: |
2015 |
| Journal: |
Nat Commun |
| Title: |
A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. |
| Volume: |
6 |
|
| Pages: |
7014 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spindel ON |
| Year: |
2014 |
| Journal: |
Circ Res |
| Title: |
Thioredoxin-interacting protein is a biomechanical regulator of Src activity: key role in endothelial cell stress fiber formation. |
| Volume: |
114 |
| Issue: |
7 |
| Pages: |
1125-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masson E |
| Year: |
2009 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice. |
| Volume: |
296 |
| Issue: |
6 |
| Pages: |
E1251-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdelsaid MA |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
e110388 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lerner AG |
| Year: |
2012 |
| Journal: |
Cell Metab |
| Title: |
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
250-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou R |
| Year: |
2010 |
| Journal: |
Nat Immunol |
| Title: |
Thioredoxin-interacting protein links oxidative stress to inflammasome activation. |
| Volume: |
11 |
| Issue: |
2 |
| Pages: |
136-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muri J |
| Year: |
2020 |
| Journal: |
Elife |
| Title: |
Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip. |
| Volume: |
9 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dotimas JR |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Diabetes regulates fructose absorption through thioredoxin-interacting protein. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang XQ |
| Year: |
2012 |
| Journal: |
Circ Res |
| Title: |
Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2. |
| Volume: |
110 |
| Issue: |
4 |
| Pages: |
560-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jo S |
| Year: |
2018 |
| Journal: |
Diabetes |
| Title: |
miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function. |
| Volume: |
67 |
| Issue: |
2 |
| Pages: |
256-264 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu G |
| Year: |
2013 |
| Journal: |
Nat Med |
| Title: |
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. |
| Volume: |
19 |
| Issue: |
9 |
| Pages: |
1141-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zervou S |
| Year: |
2013 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
A role for thioredoxin-interacting protein (Txnip) in cellular creatine homeostasis. |
| Volume: |
305 |
| Issue: |
2 |
| Pages: |
E263-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu B |
| Year: |
2022 |
| Journal: |
Endocrinology |
| Title: |
Alpha Cell Thioredoxin-interacting Protein Deletion Improves Diabetes-associated Hyperglycemia and Hyperglucagonemia. |
| Volume: |
163 |
| Issue: |
11 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Papadia S |
| Year: |
2008 |
| Journal: |
Nat Neurosci |
| Title: |
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
476-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2008 |
| Journal: |
Diabetes |
| Title: |
Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis. |
| Volume: |
57 |
| Issue: |
4 |
| Pages: |
938-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshioka J |
| Year: |
2012 |
| Journal: |
J Clin Invest |
| Title: |
Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury. |
| Volume: |
122 |
| Issue: |
1 |
| Pages: |
267-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ismael S |
| Year: |
2021 |
| Journal: |
Neurobiol Dis |
| Title: |
Thioredoxin interacting protein regulates age-associated neuroinflammation. |
| Volume: |
156 |
|
| Pages: |
105399 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abais JM |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia. |
| Volume: |
289 |
| Issue: |
39 |
| Pages: |
27159-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Filios SR |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis. |
| Volume: |
289 |
| Issue: |
52 |
| Pages: |
36275-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2008 |
| Journal: |
FASEB J |
| Title: |
Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes. |
| Volume: |
22 |
| Issue: |
10 |
| Pages: |
3581-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aldoghachi AF |
| Year: |
2024 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Fluorinated curcumin derivative (Shiga-Y6) modulates the level of thioredoxin-interacting protein (TXNIP) in a mouse model of diabetes. |
| Volume: |
694 |
|
| Pages: |
149392 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He X |
| Year: |
2012 |
| Journal: |
Mol Pharmacol |
| Title: |
Redox regulation by nuclear factor erythroid 2-related factor 2: gatekeeping for the basal and diabetes-induced expression of thioredoxin-interacting protein. |
| Volume: |
82 |
| Issue: |
5 |
| Pages: |
887-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshioka J |
| Year: |
2007 |
| Journal: |
Circ Res |
| Title: |
Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload. |
| Volume: |
101 |
| Issue: |
12 |
| Pages: |
1328-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Myers RB |
| Year: |
2016 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart. |
| Volume: |
310 |
| Issue: |
11 |
| Pages: |
H1748-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He K |
| Year: |
2017 |
| Journal: |
Oncotarget |
| Title: |
Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development. |
| Volume: |
8 |
| Issue: |
23 |
| Pages: |
37657-37672 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wen Y |
| Year: |
2018 |
| Journal: |
Int J Biochem Cell Biol |
| Title: |
mROS-TXNIP axis activates NLRP3 inflammasome to mediate renal injury during ischemic AKI. |
| Volume: |
98 |
|
| Pages: |
43-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Panse M |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
e0198016 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patwari P |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange. |
| Volume: |
281 |
| Issue: |
31 |
| Pages: |
21884-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jing G |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2. |
| Volume: |
289 |
| Issue: |
17 |
| Pages: |
11807-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park MJ |
| Year: |
2014 |
| Journal: |
J Hepatol |
| Title: |
Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo. |
| Volume: |
61 |
| Issue: |
5 |
| Pages: |
1151-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bodnar JS |
| Year: |
2002 |
| Journal: |
Nat Genet |
| Title: |
Positional cloning of the combined hyperlipidemia gene Hyplip1. |
| Volume: |
30 |
| Issue: |
1 |
| Pages: |
110-6 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|