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Search results 1 to 100 out of 5336 for Tyr

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
SO Term
Publication  
First Author: Dickie MM
Year: 1969
Journal: Mouse News Lett
Title: Remutations: Tyr and A - white-bellied agouti.
Volume: 40
Pages: 29
Publication
First Author: Mitra D
Year: 2012
Journal: Nature
Title: An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Volume: 491
Issue: 7424
Pages: 449-53
Publication
First Author: Tonks ID
Year: 2003
Journal: Genesis
Title: Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues.
Volume: 37
Issue: 3
Pages: 131-8
Publication
First Author: Puig I
Year: 2009
Journal: Pigment Cell Melanoma Res
Title: The tyrosinase promoter is active in a subset of vagal neural crest cells during early development in mice.
Volume: 22
Issue: 3
Pages: 331-4
Publication
First Author: Denecker G
Year: 2014
Journal: Cell Death Differ
Title: Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.
Volume: 21
Issue: 8
Pages: 1250-61
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Arnold C
Year: 2010
Journal: MGI Direct Data Submission
Title: Pale rider is an allele of Tyr and causes albinism
Publication  
First Author: Whitmore S
Year: 1983
Journal: Mouse News Lett
Title: Coat color variant - Tyr
Volume: 69
Pages: 19
Publication
First Author: Gluecksohn-Waelsch S
Year: 1974
Journal: Proc Natl Acad Sci U S A
Title: Complementation studies of lethal alleles in the mouse causing deficiencies of glucose-6-phosphatase, tyrosine aminotransferase, and serine dehydratase.
Volume: 71
Issue: 3
Pages: 825-9
Publication
First Author: Lyon MF
Year: 1979
Journal: Mutat Res
Title: Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation.
Volume: 63
Issue: 1
Pages: 161-73
Publication
First Author: Wines ME
Year: 1998
Journal: Genomics
Title: Physical localization of the mouse aryl hydrocarbon receptor nuclear translocator-2 (Arnt2) gene within the c112K deletion.
Volume: 51
Issue: 2
Pages: 223-32
Publication
First Author: Wines ME
Year: 2000
Journal: Genomics
Title: Physical localization of the mesoderm development (mesd) functional region.
Volume: 68
Issue: 3
Pages: 322-9
Publication
First Author: Wines ME
Year: 2001
Journal: Genomics
Title: Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis.
Volume: 72
Issue: 1
Pages: 88-98
GO Term
Allele
Name: tyrosinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication      
First Author: Medical Research Council (MRC) Harwell
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/01/26
Publication
First Author: Lavado A
Year: 2005
Journal: J Biol Chem
Title: Molecular basis of the extreme dilution mottled mouse mutation: a combination of coding and noncoding genomic alterations.
Volume: 280
Issue: 6
Pages: 4817-24
Chromosome Structure Variation
Type: chromosomal_deletion
Organism: Mus musculus
Chromosome Structure Variation
Type: chromosomal_deletion
Organism: Mus musculus
Chromosome Structure Variation
Type: chromosomal_deletion
Organism: Mus musculus
Chromosome Structure Variation
Type: chromosomal_deletion
Organism: Mus musculus
Chromosome Structure Variation
Type: chromosomal_deletion
Organism: Mus musculus
Allele
Name: transgene insertion 13, Marcus Bosenberg
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication  
First Author: Phillips RJS
Year: 1970
Journal: Mouse News Lett
Title: Chinchilla-mottled
Volume: 42
Pages: 26
Publication  
First Author: Phillips RJS
Year: 1966
Journal: Mouse News Lett
Title: A mottled c-locus mutant, c<22H>
Volume: 34
Pages: 27
Publication
First Author: Juriloff DM
Year: 1994
Journal: Genome
Title: Three spontaneous mutations at the albino locus in SELH/Bc mice.
Volume: 37
Issue: 2
Pages: 190-7
Strain
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, transgenic
Strain
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, transgenic
Strain
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, transgenic
Strain
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, transgenic
Strain
Attribute String: congenic, mutant strain, endonuclease-mediated mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Wan L
Year: 2017
Journal: Cancer Discov
Title: The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Volume: 7
Issue: 4
Pages: 424-441
Publication
First Author: Zhang Y
Year: 2014
Journal: Pigment Cell Melanoma Res
Title: Essential role of the molecular chaperone gp96 in regulating melanogenesis.
Volume: 27
Issue: 1
Pages: 82-9
Genotype
Symbol: Cdkn2a/Cdkn2a Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S1/Sv * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hsp90b1/Hsp90b1 Tg(Tyr-cre/ERT2)13Bos/?
Background: B6.Cg-Tg(Tyr-cre/ERT2)13Bos Hsp90b1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mc1r/Mc1r Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pikfyve/Pikfyve Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Porter S
Year: 1991
Journal: Dev Genet
Title: Mosaicism of tyrosinase-locus transcription and chromatin structure in dark vs. light melanocyte clones of homozygous chinchilla-mottled mice.
Volume: 12
Issue: 6
Pages: 393-402
Publication
First Author: Liggins MC
Year: 2018
Journal: PLoS Genet
Title: PIKfyve regulates melanosome biogenesis.
Volume: 14
Issue: 3
Pages: e1007290
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: mutant stock, congenic, transgenic, targeted mutation
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Bosenberg M
Year: 2006
Journal: Genesis
Title: Characterization of melanocyte-specific inducible Cre recombinase transgenic mice.
Volume: 44
Issue: 5
Pages: 262-7
Publication
First Author: Chen S
Year: 2019
Journal: Nat Commun
Title: Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.
Volume: 10
Issue: 1
Pages: 877
Publication
First Author: Liu S
Year: 2018
Journal: Nat Commun
Title: Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis.
Volume: 9
Issue: 1
Pages: 5426
Publication
First Author: Katlinskaya YV
Year: 2016
Journal: Cell Rep
Title: Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
Volume: 15
Issue: 1
Pages: 171-80
Publication
First Author: Harris ML
Year: 2013
Journal: Pigment Cell Melanoma Res
Title: Postnatal lineage mapping of follicular melanocytes with the Tyr::CreER(T) (2) transgene.
Volume: 26
Issue: 2
Pages: 269-74
Publication
First Author: Le Gal K
Year: 2015
Journal: Sci Transl Med
Title: Antioxidants can increase melanoma metastasis in mice.
Volume: 7
Issue: 308
Pages: 308re8
Publication
First Author: Luo X
Year: 2014
Journal: Cell Rep
Title: Isolation and molecular characterization of circulating melanoma cells.
Volume: 7
Issue: 3
Pages: 645-53
Publication
First Author: Lissanu Deribe Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Volume: 113
Issue: 9
Pages: E1296-305
Publication
First Author: Chen CF
Year: 2017
Journal: Cell Rep
Title: ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Volume: 18
Issue: 10
Pages: 2331-2342
Publication
First Author: Zhu B
Year: 2018
Journal: Nat Commun
Title: The protective role of DOT1L in UV-induced melanomagenesis.
Volume: 9
Issue: 1
Pages: 259
Publication
First Author: Cesarini V
Year: 2017
Journal: Oncogene
Title: Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.
Volume: 36
Issue: 31
Pages: 4508-4515
Publication
First Author: Peng W
Year: 2016
Journal: Cancer Discov
Title: Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Volume: 6
Issue: 2
Pages: 202-16
Publication
First Author: Muinonen-Martin AJ
Year: 2014
Journal: PLoS Biol
Title: Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.
Volume: 12
Issue: 10
Pages: e1001966
Publication
First Author: Kim SH
Year: 2017
Journal: J Invest Dermatol
Title: Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma.
Volume: 137
Issue: 8
Pages: 1740-1748
Publication
First Author: Crawford M
Year: 2017
Journal: Biol Open
Title: A reporter mouse model for in vivo tracing and in vitro molecular studies of melanocytic lineage cells and their diseases.
Volume: 6
Issue: 8
Pages: 1219-1228
Publication
First Author: Le Mercier I
Year: 2014
Journal: Cancer Res
Title: VISTA Regulates the Development of Protective Antitumor Immunity.
Volume: 74
Issue: 7
Pages: 1933-44
Publication
First Author: Claps G
Year: 2016
Journal: Cell Rep
Title: A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.
Volume: 15
Issue: 9
Pages: 1884-92
Publication
First Author: Ferguson B
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis.
Volume: 23
Issue: 6
Pages: 771-80
Publication
First Author: Karreth FA
Year: 2011
Journal: Cell
Title: In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma.
Volume: 147
Issue: 2
Pages: 382-95
Publication
First Author: Shah M
Year: 2010
Journal: PLoS Genet
Title: A role for ATF2 in regulating MITF and melanoma development.
Volume: 6
Issue: 12
Pages: e1001258
Publication
First Author: Maertens O
Year: 2013
Journal: Cancer Discov
Title: Elucidating distinct roles for NF1 in melanomagenesis.
Volume: 3
Issue: 3
Pages: 338-49
Publication
First Author: Long JE
Year: 2019
Journal: Cell Death Differ
Title: Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.
Volume: 26
Issue: 11
Pages: 2416-2429
Publication
First Author: Rahman H
Year: 2021
Journal: J Invest Dermatol
Title: Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo.
Volume: 141
Issue: 1
Pages: 132-141.e3
Publication
First Author: Brady DC
Year: 2017
Journal: Cancer Res
Title: Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors.
Volume: 77
Issue: 22
Pages: 6240-6252
Publication
First Author: Shakhova O
Year: 2015
Journal: PLoS Genet
Title: Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.
Volume: 11
Issue: 1
Pages: e1004877
Publication    
First Author: Ruiz-Vega R
Year: 2020
Journal: Elife
Title: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes.
Volume: 9
Publication
First Author: Crawford M
Year: 2020
Journal: J Invest Dermatol
Title: Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin.
Volume: 140
Issue: 2
Pages: 425-434.e10
Publication
First Author: Yuan P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
Volume: 110
Issue: 45
Pages: 18226-31
Publication
First Author: Shakhova O
Year: 2012
Journal: Nat Cell Biol
Title: Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.
Volume: 14
Issue: 8
Pages: 882-90
Publication
First Author: Di Leo L
Year: 2021
Journal: Nat Commun
Title: Loss of Ambra1 promotes melanoma growth and invasion.
Volume: 12
Issue: 1
Pages: 2550
Publication
First Author: González-Sánchez E
Year: 2013
Journal: PLoS One
Title: Lkb1 loss promotes tumor progression of BRAF(V600E)-induced lung adenomas.
Volume: 8
Issue: 6
Pages: e66933
Publication
First Author: Shurin GV
Year: 2019
Journal: Cancer Res
Title: Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth.
Volume: 79
Issue: 10
Pages: 2736-2747
Genotype
Symbol: Cdkn2a/Cdkn2a Ctnnb1/Ctnnb1 Pten/Pten Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129/Sv * C57BL/6J * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kras/Kras<+> Trp53/Trp53<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S4/SvJae * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Braf/Braf Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/? TgTn(sb-T2/Onc)#Dla/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox10/Sox10<+> Tg(Tyr-cre/ERT2)13Bos/? Tg(Tyr-NRAS*Q61K)1Bee/?
Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/? Tg(Tyr-NRAS*Q61K)1Bee/?
Background: FVB.Cg-Tg(Tyr-cre/ERT2)13Bos Trp53 Tg(Tyr-NRAS*Q61K)1Bee
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: C3FeJ.Cg-Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a
Zygosity: cn
Has Mutant Allele: true