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Search results 1 to 95 out of 95 for Uba5

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
79876 | UBA5
Type: gene
Organism: human
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Gene
448010 | uba5
Type: gene
Organism: frog, western clawed
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Gene
300968 | Uba5
Type: gene
Organism: rat
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Gene
460705 | UBA5
Type: gene
Organism: chimpanzee
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Gene
509292 | UBA5
Type: gene
Organism: cattle
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Gene
100856526 | UBA5
Type: gene
Organism: dog, domestic
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Gene
414879 | UBA5
Type: gene
Organism: chicken
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Gene
386712 | uba5
Type: gene
Organism: zebrafish
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Gene
717647 | UBA5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1913913 | Uba5
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100126822 | UBA5P1
Type: gene
Organism: human
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Publication
26872069 | J:237644
First Author: Duan R
Year: 2016
Journal: PLoS One
Title: UBA5 Mutations Cause a New Form of Autosomal Recessive Cerebellar Ataxia.
Volume: 11
Issue: 2
Pages: e0149039
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Publication
21304510 | J:289448
 
First Author: Tatsumi K
Year: 2011
Journal: Nat Commun
Title: The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.
Volume: 2
Pages: 181
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Publication
20018847 | J:158995
First Author: Tatsumi K
Year: 2010
Journal: J Biol Chem
Title: A novel type of E3 ligase for the Ufm1 conjugation system.
Volume: 285
Issue: 8
Pages: 5417-27
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Publication
23152784 | J:195351
First Author: Zhang Y
Year: 2012
Journal: PLoS One
Title: Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Volume: 7
Issue: 11
Pages: e48587
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Protein Coding Gene
MGP_CAROLIEiJ_G0032595 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035204 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035184 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035116 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035177 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034887 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034965 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035093 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035004 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035719 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015463 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033741 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423431
Age: embryonic day 16.5
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423431
Age: embryonic day 16.5
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423431
Age: embryonic day 16.5
Image: 6
Specimen Label: KO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423431
Age: embryonic day 16.5
Image: 6
Specimen Label: KO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423440
Age: postnatal month 1
Image: S6
Specimen Label: Con
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423440
Age: postnatal month 1
Image: S6
Specimen Label: Con
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423440
Age: postnatal month 1
Image: S6
Specimen Label: CKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6423135
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423440
Age: postnatal month 1
Image: S6
Specimen Label: CKO
Detected: true
Specimen Num: 4
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Publication
33372156 | J:300137
 
First Author: Balce DR
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages.
Volume: 118
Issue: 1
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Publication
- | J:358610
     
First Author: Baylor College of Medicine
Year: 2024
Journal: MGI Direct Data Submission
Title: Baylor College of Medicine Alleles.
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Publication
30635284 | J:272566
 
First Author: Yang R
Year: 2019
Journal: Development
Title: CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Volume: 146
Issue: 2
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
27545674 | J:240522
First Author: Muona M
Year: 2016
Journal: Am J Hum Genet
Title: Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy.
Volume: 99
Issue: 3
Pages: 683-694
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Allele
Uba5<em1Bay> | MGI:7768051
Name: ubiquitin-like modifier activating enzyme 5; targeted mutation 1, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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Allele
Uba5<em2Bay> | MGI:7768052
Name: ubiquitin-like modifier activating enzyme 5; targeted mutation 2, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Uba5<em3Bay> | MGI:7768053
Name: ubiquitin-like modifier activating enzyme 5; targeted mutation 3, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Uba5<em4Bay> | MGI:7768054
Name: ubiquitin-like modifier activating enzyme 5; targeted mutation 4, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Uba5<em5Bay> | MGI:7768055
Name: ubiquitin-like modifier activating enzyme 5; targeted mutation 5, Baylor College of Medicine
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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DO Term
DOID:0111615 | autosomal recessive spinocerebellar ataxia 24
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DO Term
DOID:0080424 | developmental and epileptic encephalopathy 44
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Publication
10884686 | -
First Author: Jentsch S
Year: 2000
Journal: Trends Cell Biol
Title: Ubiquitin and its kin: how close are the family ties?
Volume: 10
Issue: 8
Pages: 335-42
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Publication
16527251 | -
First Author: Sasakawa H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1.
Volume: 343
Issue: 1
Pages: 21-6
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Protein Domain
IPR005375 | UFM1
Type: Family
Description: This entry represents Ufm1 (ubiquitin-fold modifier), which is a ubiquitin-like protein with structural similarities to ubiquitin [, ]. Ufm1 is one of a number of ubiquitin-like modifiers that conjugate to target proteins in cells through Uba5 (E1) and Ufc1 (E2). The Ufm1-system is conserved in metazoa and plants, suggesting it has a potential role in multicellular organisms []. Human Ufm1 is synthesized as a precursor consisting of 85 amino-acid residues. Prior to activation by Uba5, the extra amino acids at the C-terminal region of Ufm1 are removed to expose Gly, which is necessary for conjugation to target molecule(s). C-terminal processing of Ufm1 requires two specific cysteine peptidases (): UfSP1 and UfSP2; both peptidases are also able to release Ufm1 from Ufm1-conjugated cellular proteins. UfSP2 is present in most, if not all, of multi-cellular organisms including plant, nematode, fly, and mammal, whereas UfSP1 is not present in plants and nematodes [].
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Publication
25219498 | J:215542
First Author: Yoo HM
Year: 2014
Journal: Mol Cell
Title: Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development.
Volume: 56
Issue: 2
Pages: 261-74
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Protein
P61961
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
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Protein
D3YW97
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
H7BWZ1
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: false
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Publication
30701081 | J:298771
 
First Author: Cai Y
Year: 2019
Journal: Cell Discov
Title: Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation.
Volume: 5
Pages: 7
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Publication
25952549 | J:238253
First Author: Zhang M
Year: 2015
Journal: Cell Death Differ
Title: RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis.
Volume: 22
Issue: 12
Pages: 1922-34
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Publication
34148841 | J:333688
First Author: Zhou Y
Year: 2021
Journal: J Genet Genomics
Title: Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis.
Volume: 48
Issue: 5
Pages: 403-410
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Publication
17182609 | J:120365
First Author: Kang SH
Year: 2007
Journal: J Biol Chem
Title: Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2.
Volume: 282
Issue: 8
Pages: 5256-62
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Publication
26544067 | J:231701
First Author: Cai Y
Year: 2015
Journal: PLoS Genet
Title: UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development.
Volume: 11
Issue: 11
Pages: e1005643
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Publication
15071506 | -
First Author: Komatsu M
Year: 2004
Journal: EMBO J
Title: A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
Volume: 23
Issue: 9
Pages: 1977-86
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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