Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Bao J |
Year: |
2010 |
Journal: |
Mol Cell Endocrinol |
Title: |
UBQLN1 interacts with SPEM1 and participates in spermiogenesis. |
Volume: |
327 |
Issue: |
1-2 |
Pages: |
89-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2020 |
Journal: |
Acta Neuropathol Commun |
Title: |
Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD. |
Volume: |
8 |
Issue: |
1 |
Pages: |
164 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiao F |
Year: |
2017 |
Journal: |
Physiol Rep |
Title: |
Reduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteins. |
Volume: |
5 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adegoke OO |
Year: |
2017 |
Journal: |
J Alzheimers Dis |
Title: |
Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-β Accumulation in Mice. |
Volume: |
59 |
Issue: |
2 |
Pages: |
575-590 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Ubiquilin-1 protects cells from oxidative stress and ischemic stroke caused tissue injury in mice. |
Volume: |
34 |
Issue: |
8 |
Pages: |
2813-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakowski ET |
Year: |
2015 |
Journal: |
PLoS Pathog |
Title: |
Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis. |
Volume: |
11 |
Issue: |
7 |
Pages: |
e1005076 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mohan HM |
Year: |
2022 |
Journal: |
Cell Mol Life Sci |
Title: |
RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. |
Volume: |
79 |
Issue: |
3 |
Pages: |
176 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Rothenberg C |
Year: |
2010 |
Journal: |
Hum Mol Genet |
Title: |
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy. |
Volume: |
19 |
Issue: |
16 |
Pages: |
3219-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas N |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
The ubiquitin-like protein PLIC-1 or ubiquilin 1 inhibits TLR3-Trif signaling. |
Volume: |
6 |
Issue: |
6 |
Pages: |
e21153 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanaoka E |
Year: |
2000 |
Journal: |
J Hum Genet |
Title: |
Molecular cloning and expression analysis of the human DA41 gene and its mapping to chromosome 9q21.2-q21.3. |
Volume: |
45 |
Issue: |
3 |
Pages: |
188-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beverly LJ |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1. |
Volume: |
109 |
Issue: |
3 |
Pages: |
E119-26 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7510206 |
Assay Type: |
Western blot |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7511462 |
Age: |
postnatal |
Image: |
5 |
|
Specimen Label: |
Input Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7510206 |
Assay Type: |
Western blot |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7511462 |
Age: |
postnatal |
Image: |
5 |
|
Specimen Label: |
Input Rpn10LdeltaUIM |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7510206 |
Assay Type: |
Western blot |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7511471 |
Age: |
postnatal |
Image: |
5 |
|
Specimen Label: |
Input Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7510206 |
Assay Type: |
Western blot |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7511471 |
Age: |
postnatal |
Image: |
5 |
|
Specimen Label: |
Input Rpn13LKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7510206 |
Assay Type: |
Western blot |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7511480 |
Age: |
postnatal |
Image: |
5 |
|
Specimen Label: |
Input Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7510206 |
Assay Type: |
Western blot |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7511480 |
Age: |
postnatal |
Image: |
5 |
|
Specimen Label: |
Input DKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kleijnen MF |
Year: |
2000 |
Journal: |
Mol Cell |
Title: |
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. |
Volume: |
6 |
Issue: |
2 |
Pages: |
409-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Natunen T |
Year: |
2016 |
Journal: |
Neurobiol Dis |
Title: |
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models. |
Volume: |
85 |
|
Pages: |
187-205 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu AL |
Year: |
1999 |
Journal: |
Mol Cell |
Title: |
Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane. |
Volume: |
4 |
Issue: |
4 |
Pages: |
619-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rutherford NJ |
Year: |
2013 |
Journal: |
Brain Res |
Title: |
Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions. |
Volume: |
1524 |
|
Pages: |
62-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hjerpe R |
Year: |
2016 |
Journal: |
Cell |
Title: |
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. |
Volume: |
166 |
Issue: |
4 |
Pages: |
935-949 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamazaki J |
Year: |
2015 |
Journal: |
PLoS Genet |
Title: |
Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. |
Volume: |
11 |
Issue: |
7 |
Pages: |
e1005401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tian C |
Year: |
2019 |
Journal: |
Dev Biol |
Title: |
TBX1 is required for normal stria vascularis and semicircular canal development. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Nedomova M |
Year: |
2024 |
Journal: |
iScience |
Title: |
DDI2 protease controls embryonic development and inflammation via TCF11/NRF1. |
Volume: |
27 |
Issue: |
10 |
Pages: |
110893 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Backcross DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX BSS Panel Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Mouse Synonym Curation |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
582
 |
Fragment?: |
false |
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Interaction Experiment |
Description: |
UBQLN1 interacts with SPEM1 and participates in spermiogenesis. |
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Allele |
Name: |
ubiquilin 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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Allele |
Name: |
transgene insertion 2, Hongmin Wang |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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Genotype |
Symbol: |
Tg(CAG-Ubqln1)2Hmw/? |
Background: |
involves: C57BL/6 * SJL |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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Publication |
First Author: |
Whiteley AM |
Year: |
2017 |
Journal: |
Elife |
Title: |
Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins. |
Volume: |
6 |
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Publication |
First Author: |
Hu C |
Year: |
2018 |
Journal: |
J Clin Invest |
Title: |
Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury. |
Volume: |
128 |
Issue: |
12 |
Pages: |
5294-5306 |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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