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Search results 1 to 100 out of 102 for Ucn2

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Type Details Score
Gene
90226 | UCN2
Type: gene
Organism: human
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Gene
751828 | UCN2
Type: gene
Organism: cattle
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Gene
100683848 | UCN2
Type: gene
Organism: dog, domestic
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Gene
104005556 | UCN2
Type: gene
Organism: chimpanzee
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Gene
106996925 | UCN2
Type: gene
Organism: macaque, rhesus
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Gene
170896 | Ucn2
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2176375 | Ucn2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
37402735 | J:337832
First Author: Flaherty SE 3rd
Year: 2023
Journal: Nat Commun
Title: Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.
Volume: 14
Issue: 1
Pages: 3953
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Publication
22640813 | J:190480
First Author: Breu J
Year: 2012
Journal: Behav Brain Res
Title: Urocortin 2 modulates aspects of social behaviour in mice.
Volume: 233
Issue: 2
Pages: 331-6
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Publication
25426872 | J:220767
First Author: Voltolini C
Year: 2015
Journal: Endocrinology
Title: Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition.
Volume: 156
Issue: 2
Pages: 670-9
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Publication
23320836 | J:195175
First Author: Tillinger A
Year: 2013
Journal: J Neurochem
Title: Stress-induced changes in gene expression of urocortin 2 and other CRH peptides in rat adrenal medulla: involvement of glucocorticoids.
Volume: 125
Issue: 2
Pages: 185-92
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Publication
18308934 | J:132850
First Author: Hao Z
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation.
Volume: 105
Issue: 10
Pages: 3939-44
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Publication
27699250 | J:290937
First Author: Gao MH
Year: 2016
Journal: JCI Insight
Title: One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance.
Volume: 1
Issue: 15
Pages: e88322
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Publication
16424218 | J:126417
First Author: Tsatsanis C
Year: 2006
Journal: J Immunol
Title: Corticotropin-releasing factor and the urocortins induce the expression of TLR4 in macrophages via activation of the transcription factors PU.1 and AP-1.
Volume: 176
Issue: 3
Pages: 1869-77
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Publication
38081372 | J:346005
 
First Author: Zhu C
Year: 2024
Journal: Biochem Pharmacol
Title: Urocortin2 attenuates diabetic coronary microvascular dysfunction by regulating macrophage extracellular vesicles.
Volume: 219
Pages: 115976
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Protein Coding Gene
MGP_CAROLIEiJ_G0032710 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035292 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035002 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2176375 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035118 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034020 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015578 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033855 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16707802 | J:108744
First Author: Chen A
Year: 2006
Journal: J Neurosci
Title: Urocortin 2-deficient mice exhibit gender-specific alterations in circadian hypothalamus-pituitary-adrenal axis and depressive-like behavior.
Volume: 26
Issue: 20
Pages: 5500-10
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Publication
17050686 | J:116101
First Author: Chen A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle.
Volume: 103
Issue: 44
Pages: 16580-5
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Publication
11329063 | J:114061
First Author: Hsu SY
Year: 2001
Journal: Nat Med
Title: Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor.
Volume: 7
Issue: 5
Pages: 605-11
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Publication
15514029 | J:95540
First Author: Chen A
Year: 2005
Journal: Mol Endocrinol
Title: Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids.
Volume: 19
Issue: 2
Pages: 441-58
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Publication
11226328 | J:67860
First Author: Reyes TM
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors.
Volume: 98
Issue: 5
Pages: 2843-8
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Publication
20937857 | J:166245
First Author: Neufeld-Cohen A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery.
Volume: 107
Issue: 44
Pages: 19020-5
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Publication
28665499 | J:328059
First Author: Burns DP
Year: 2017
Journal: Exp Physiol
Title: Restoration of pharyngeal dilator muscle force in dystrophin-deficient (mdx) mice following co-treatment with neutralizing interleukin-6 receptor antibodies and urocortin 2.
Volume: 102
Issue: 9
Pages: 1177-1193
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Publication
22192627 | J:179990
First Author: Reutenauer-Patte J
Year: 2012
Journal: Am J Pathol
Title: Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways.
Volume: 180
Issue: 2
Pages: 749-62
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Publication
20610744 | J:161776
First Author: Deussing JM
Year: 2010
Journal: J Neurosci
Title: Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2.
Volume: 30
Issue: 27
Pages: 9103-16
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Publication
11416224 | J:70028
First Author: Lewis K
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor.
Volume: 98
Issue: 13
Pages: 7570-5
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Protein
Q9QZQ3
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
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Protein Coding Gene
MGI:1346329 | Uts2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25942073 | J:220369
First Author: Spyroglou A
Year: 2015
Journal: Endocrinology
Title: Adrenal and Ovarian Phenotype of a Tissue-Specific Urocortin 2-Overexpressing Mouse Model.
Volume: 156
Issue: 7
Pages: 2646-56
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Allele
Gt(ROSA)26Sor<tm2(Ucn2)Jde> | MGI:5634348
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Jan Deussing
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Publication
28550160 | J:244036
First Author: Tsuda T
Year: 2017
Journal: J Exp Med
Title: Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction.
Volume: 214
Issue: 7
Pages: 1877-1888
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Publication
34883278 | J:318732
 
First Author: Meister J
Year: 2022
Journal: Mol Metab
Title: In vivo metabolic effects after acute activation of skeletal muscle Gs signaling.
Volume: 55
Pages: 101415
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Publication
20731720 | J:183524
First Author: Giardino WJ
Year: 2011
Journal: Genes Brain Behav
Title: Dissection of corticotropin-releasing factor system involvement in locomotor sensitivity to methamphetamine.
Volume: 10
Issue: 1
Pages: 78-89
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Publication
27500935 | J:254575
First Author: Arase S
Year: 2016
Journal: PLoS One
Title: Disturbance in the Mucosa-Associated Commensal Bacteria Is Associated with the Exacerbation of Chronic Colitis by Repeated Psychological Stress; Is That the New Target of Probiotics?
Volume: 11
Issue: 8
Pages: e0160736
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Publication
29247629 | J:268751
 
First Author: Bagosi Z
Year: 2018
Journal: Brain Res
Title: Anxiolytic- and antidepressant-like actions of Urocortin 2 and its fragments in mice.
Volume: 1680
Pages: 62-68
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Publication
8243652 | J:15698
First Author: Vita N
Year: 1993
Journal: FEBS Lett
Title: Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors.
Volume: 335
Issue: 1
Pages: 1-5
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Publication
7692441 | -
First Author: Chen R
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Expression cloning of a human corticotropin-releasing-factor receptor.
Volume: 90
Issue: 19
Pages: 8967-71
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Publication
23863939 | -
First Author: Hollenstein K
Year: 2013
Journal: Nature
Title: Structure of class B GPCR corticotropin-releasing factor receptor 1.
Volume: 499
Issue: 7459
Pages: 438-43
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Publication
8536612 | -
First Author: Yu J
Year: 1996
Journal: Endocrinology
Title: Molecular cloning of a type A chicken corticotropin-releasing factor receptor with high affinity for urotensin I.
Volume: 137
Issue: 1
Pages: 192-7
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Publication
7846062 | -
First Author: Lovenberg TW
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.
Volume: 92
Issue: 3
Pages: 836-40
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Publication
8536644 | -
First Author: Liaw CW
Year: 1996
Journal: Endocrinology
Title: Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid.
Volume: 137
Issue: 1
Pages: 72-7
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Protein Domain
IPR003051 | GPCR_2_CRF_rcpt
Type: Family
Description: G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups []. The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence []. The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) [, , , , ]. GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice []. Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs [].The secretin-like GPCRs include secretin [], calcitonin [], parathyroid hormone/parathyroid hormone-related peptides []and vasoactive intestinal peptide [], all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway. These receptors contain seven transmembrane regions, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins (however there is no significant sequence identity between these families, the secretin-like receptors thus bear their own unique '7TM' signature). Their N-terminal is probably located on the extracellular side of the membrane and potentially glycosylated. This N-terminal region contains a long conserved region which allows the binding of large peptidic ligand such as glucagon, secretin, VIP and PACAP; this region contains five conserved cysteines residues which could be involved in disulphide bond. The C-terminal region of these receptor is probably cytoplasmic. Every receptor gene in this family is encoded on multiple exons, and several of these genes are alternatively spliced to yield functionally distinct products. Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis, playing an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge []. The CRF receptor has been found in human cortex tissue, pituitary, brainstem and testis []. The protein comprises 415 amino acid residues with the characteristic 7TM architecture of the secretin-like GPCR superfamily. Three isoforms (designated CRF-R1, CRF-R2 and CRF-R3) are produced as a result of alternative splicing of the same gene: CRF-R1 appears to be the predominant form; CRF-R3 does not bind to CRF with a high affinity []. CRF and the related urocortin peptides (Ucn 1-3, also known as UCN, UCN2 and UCN3) mediate their actions through two CRF1 and CRF2 [].
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Protein Domain
IPR003052 | GPCR_2_CRF1_rcpt
Type: Family
Description: G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups []. The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence []. The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) [, , , , ]. GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice []. Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs [].The secretin-like GPCRs include secretin [], calcitonin [], parathyroid hormone/parathyroid hormone-related peptides []and vasoactive intestinal peptide [], all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway. These receptors contain seven transmembrane regions, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins (however there is no significant sequence identity between these families, the secretin-like receptors thus bear their own unique '7TM' signature). Their N-terminal is probably located on the extracellular side of the membrane and potentially glycosylated. This N-terminal region contains a long conserved region which allows the binding of large peptidic ligand such as glucagon, secretin, VIP and PACAP; this region contains five conserved cysteines residues which could be involved in disulphide bond. The C-terminal region of these receptor is probably cytoplasmic. Every receptor gene in this family is encoded on multiple exons, and several of these genes are alternatively spliced to yield functionally distinct products. Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis, playing an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge []. The CRF receptor has been found in human cortex tissue, pituitary, brainstem and testis []. The protein comprises 415 amino acid residues with the characteristic 7TM architecture of the secretin-like GPCR superfamily. Three isoforms (designated CRF-R1, CRF-R2 and CRF-R3) are produced as a result of alternative splicing of the same gene: CRF-R1 appears to be the predominant form; CRF-R3 does not bind to CRF with a high affinity []. CRF and the related urocortin peptides (Ucn 1-3, also known as UCN, UCN2 and UCN3) mediate their actions through two CRF1 and CRF2 [].The sequence of the CRF-R is highly conserved from avian to mammalian species, the majority of the sequence divergence occuring in the putativesignal peptide and extracellular N-terminal domain []. Five additional amino acids are inserted in the N terminus of the avian receptor, and despite its overall similarity to the type 1 mammalian CRF-R, its ligand binding properties are similar to those of the type 2 receptor (i.e., has a higher affinity for urotensin I than for CRF) []. This entry includes CRF1 receptor (CRF1R, also known as CRHR1), which is activated by CRF and Ucn1, is expressed in brain areas including the pituitary, hypothalamus, amygdala and cortex. It is an interesting target to develop drug treatments for stress-related conditions such as anxiety, depression and irritable bowel syndrome [].
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Protein Domain
IPR003053 | GPCR_2_CRF2_rcpt
Type: Family
Description: G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups []. The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence []. The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) [, , , , ]. GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice []. Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs [].The secretin-like GPCRs include secretin [], calcitonin [], parathyroid hormone/parathyroid hormone-related peptides []and vasoactive intestinal peptide [], all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway. These receptors contain seven transmembrane regions, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins (however there is no significant sequence identity between these families, the secretin-like receptors thus bear their own unique '7TM' signature). Their N-terminal is probably located on the extracellular side of the membrane and potentially glycosylated. This N-terminal region contains a long conserved region which allows the binding of large peptidic ligand such as glucagon, secretin, VIP and PACAP; this region contains five conserved cysteines residues which could be involved in disulphide bond. The C-terminal region of these receptor is probably cytoplasmic. Every receptor gene in this family is encoded on multiple exons, and several of these genes are alternatively spliced to yield functionally distinct products. Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis, playing an important role in coordinating the endocrine, autonomic and behavioral responses to stress and immune challenge []. The CRF receptor has been found in human cortex tissue, pituitary, brainstem and testis []. The protein comprises 415 amino acid residues with the characteristic 7TM architecture of the secretin-like GPCR superfamily. Three isoforms (designated CRF-R1, CRF-R2 and CRF-R3) are produced as a result of alternative splicing of the same gene: CRF-R1 appears to be the predominant form; CRF-R3 does not bind to CRF with a high affinity []. CRF and the related urocortin peptides (Ucn 1-3, also known as UCN, UCN2 and UCN3) mediate their actions through two CRF1 and CRF2 [].For the CRF-R2 receptor, at least 2 splice forms with different 5'-coding sequences (CRF2 alpha and CRF2 beta) have been identified in rat []. The sequence of the CRF-R is highly conserved between species, the majority of the sequence divergence occuring in the putative signal peptide and extracellular N-terminal domain. The relative abundance of CRF-R2 messenger RNA appears to be lower in humans than in rats for the heart and skeletal tissues studied to date []. CRF-R2 stimulates cAMP production in response to CRF and known CRF-like agonists []. CRF and the non-mammalian CRF-related peptides sauvagine and urotensin I stimulate adenylate cyclaseactivity in a dose-dependent manner, with a rank order of potency thatdiffers from that of the CRF1 receptor (sauvagine>urotensin>=rat/human CRF>ovine CRF). The differences in the pharmacological profiles and tissue distributions of CRF-R1 and CRF-R2 suggests important functionaldifferences between the two receptors [].
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Protein
Q8VHV3
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
Q5ERJ2
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: false
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Protein
K9J9G1
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Protein
Q8VHV2
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein
Q0VGH2
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: false
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Protein
P35347
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
Q60748
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Protein
E9QNK5
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false
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Protein
E9PXI8
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Protein
A0A1D5RLK7
Organism: Mus musculus/domesticus
Length: 431  
Fragment?: false
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Protein
C0K3M3
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Protein
Q3ZAT0
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
Q3UQP0
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Publication
1646711 | -
First Author: Ishihara T
Year: 1991
Journal: EMBO J
Title: Molecular cloning and expression of a cDNA encoding the secretin receptor.
Volume: 10
Issue: 7
Pages: 1635-41
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Publication
1314625 | -
First Author: Ishihara T
Year: 1992
Journal: Neuron
Title: Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide.
Volume: 8
Issue: 4
Pages: 811-9
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Publication
1658940 | -
First Author: Lin HY
Year: 1991
Journal: Science
Title: Expression cloning of an adenylate cyclase-coupled calcitonin receptor.
Volume: 254
Issue: 5034
Pages: 1022-4
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Publication
1658941 | -
First Author: Jüppner H
Year: 1991
Journal: Science
Title: A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.
Volume: 254
Issue: 5034
Pages: 1024-6
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Publication
12679517 | J:83410
First Author: Vassilatis DK
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The G protein-coupled receptor repertoires of human and mouse.
Volume: 100
Issue: 8
Pages: 4903-8
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Publication
8170923 | -
First Author: Attwood TK
Year: 1994
Journal: Protein Eng
Title: Fingerprinting G-protein-coupled receptors.
Volume: 7
Issue: 2
Pages: 195-203
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Publication
8081729 | -
First Author: Kolakowski LF Jr
Year: 1994
Journal: Receptors Channels
Title: GCRDb: a G-protein-coupled receptor database.
Volume: 2
Issue: 1
Pages: 1-7
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Publication
15914470 | -
First Author: Foord SM
Year: 2005
Journal: Pharmacol Rev
Title: International Union of Pharmacology. XLVI. G protein-coupled receptor list.
Volume: 57
Issue: 2
Pages: 279-88
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Publication
18948278 | -
First Author: Harmar AJ
Year: 2009
Journal: Nucleic Acids Res
Title: IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels.
Volume: 37
Issue: Database issue
Pages: D680-5
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