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Search results 1 to 100 out of 438 for Ucp2

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0.054s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:4416460
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825773
Age: embryonic day 14.5
Image: Additional file 4 Ucp2
Detected: true
Specimen Num: 1
Publication
First Author: Broche B
Year: 2018
Journal: Diabetes
Title: Mitochondrial Protein UCP2 Controls Pancreas Development.
Volume: 67
Issue: 1
Pages: 78-84
Publication
First Author: Motloch LJ
Year: 2016
Journal: PLoS One
Title: By Regulating Mitochondrial Ca2+-Uptake UCP2 Modulates Intracellular Ca2+.
Volume: 11
Issue: 2
Pages: e0148359
Publication
First Author: Nübel T
Year: 2008
Journal: Biochim Biophys Acta
Title: Modified glutamine catabolism in macrophages of Ucp2 knock-out mice.
Volume: 1777
Issue: 1
Pages: 48-54
Publication
First Author: Allister EM
Year: 2013
Journal: Diabetes
Title: UCP2 regulates the glucagon response to fasting and starvation.
Volume: 62
Issue: 5
Pages: 1623-33
Protein
Organism: Mus musculus
Length: 309  
Fragment?: false
Protein
Organism: Mus musculus
Length: 309  
Fragment?: false
Publication
First Author: Emre Y
Year: 2007
Journal: Biochem J
Title: Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages.
Volume: 402
Issue: 2
Pages: 271-8
Publication
First Author: Park D
Year: 2011
Journal: Nature
Title: Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein.
Volume: 477
Issue: 7363
Pages: 220-4
Publication
First Author: Müller S
Year: 2014
Journal: PLoS One
Title: Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice.
Volume: 9
Issue: 4
Pages: e94494
Publication
First Author: Simon-Areces J
Year: 2012
Journal: PLoS One
Title: UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior.
Volume: 7
Issue: 8
Pages: e42911
Publication
First Author: Bordone L
Year: 2006
Journal: PLoS Biol
Title: Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells.
Volume: 4
Issue: 2
Pages: e31
Publication
First Author: Dalgaard LT
Year: 2012
Journal: Biochem Biophys Res Commun
Title: UCP2 mRNA expression is dependent on glucose metabolism in pancreatic islets.
Volume: 417
Issue: 1
Pages: 495-500
Publication
First Author: Diao J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival.
Volume: 105
Issue: 33
Pages: 12057-62
Publication
First Author: Berardi MJ
Year: 2014
Journal: Cell Metab
Title: Fatty acid flippase activity of UCP2 is essential for its proton transport in mitochondria.
Volume: 20
Issue: 3
Pages: 541-52
Publication
First Author: Ji F
Year: 2017
Journal: Stem Cells
Title: UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex.
Volume: 35
Issue: 6
Pages: 1479-1492
Publication
First Author: Haschemi A
Year: 2011
Journal: PLoS One
Title: Carbon monoxide induced PPARγ SUMOylation and UCP2 block inflammatory gene expression in macrophages.
Volume: 6
Issue: 10
Pages: e26376
Publication  
First Author: Varela L
Year: 2016
Journal: Neurobiol Dis
Title: Mitochondria controlled by UCP2 determine hypoxia-induced synaptic remodeling in the cortex and hippocampus.
Volume: 90
Pages: 68-74
Publication
First Author: Zhou Y
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: UCP2 attenuates apoptosis of tubular epithelial cells in renal ischemia-reperfusion injury.
Volume: 313
Issue: 4
Pages: F926-F937
Publication
First Author: Kukat A
Year: 2014
Journal: PLoS Genet
Title: Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity.
Volume: 10
Issue: 6
Pages: e1004385
Publication
First Author: Zhou M
Year: 2012
Journal: PLoS One
Title: Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K.
Volume: 7
Issue: 2
Pages: e32349
Publication
First Author: Toda C
Year: 2016
Journal: Cell
Title: UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness.
Volume: 164
Issue: 5
Pages: 872-83
Publication
First Author: de Bilbao F
Year: 2004
Journal: J Neurochem
Title: Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels.
Volume: 89
Issue: 5
Pages: 1283-92
Publication
First Author: Tsuboyama-Kasaoka N
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Studies of UCP2 transgenic and knockout mice reveal that liver UCP2 is not essential for the antiobesity effects of fish oil.
Volume: 294
Issue: 3
Pages: E600-6
Publication
First Author: Alves-Guerra MC
Year: 2012
Journal: PLoS One
Title: Analysis of uncoupling protein 2-deficient mice upon anaesthesia and sedation revealed a role for UCP2 in locomotion.
Volume: 7
Issue: 8
Pages: e41846
Publication  
First Author: Wang D
Year: 2014
Journal: Neuroscience
Title: Hippocampal UCP2 is essential for cognition and resistance to anxiety but not required for the benefits of exercise.
Volume: 277
Pages: 36-44
Publication
First Author: Aheng C
Year: 2011
Journal: PLoS One
Title: Deletion of UCP2 in iNOS deficient mice reduces the severity of the disease during experimental autoimmune encephalomyelitis.
Volume: 6
Issue: 8
Pages: e22841
Publication  
First Author: Caron A
Year: 2017
Journal: Biochimie
Title: Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue.
Volume: 134
Pages: 118-126
Publication
First Author: Andrews ZB
Year: 2008
Journal: Nature
Title: UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.
Volume: 454
Issue: 7206
Pages: 846-51
Publication
First Author: Emre Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes.
Volume: 104
Issue: 48
Pages: 19085-90
Publication
First Author: Elorza A
Year: 2008
Journal: J Biol Chem
Title: UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis.
Volume: 283
Issue: 45
Pages: 30461-70
Publication
First Author: Oh KS
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Liver PPARalpha and UCP2 are involved in the regulation of obesity and lipid metabolism by swim training in genetically obese db/db mice.
Volume: 345
Issue: 3
Pages: 1232-9
Publication
First Author: Mattiasson G
Year: 2003
Journal: Nat Med
Title: Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma.
Volume: 9
Issue: 8
Pages: 1062-8
Publication
First Author: Horvath B
Year: 2002
Journal: Biochem Pharmacol
Title: Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold.
Volume: 64
Issue: 3
Pages: 369-74
Publication
First Author: Asami DK
Year: 2008
Journal: Exp Gerontol
Title: Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice.
Volume: 43
Issue: 12
Pages: 1069-76
Publication
First Author: McDonald RB
Year: 2008
Journal: Exp Gerontol
Title: Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice.
Volume: 43
Issue: 12
Pages: 1061-8
Publication
First Author: Suski JM
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: new evidence for a putative novel function of uncoupling proteins as superoxide anion transporters.
Volume: 428
Issue: 2
Pages: 234-8
Publication  
First Author: Hirose M
Year: 2018
Journal: Mitochondrion
Title: The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice.
Volume: 42
Pages: 50-53
Publication
First Author: Flachs P
Year: 2007
Journal: FEBS Lett
Title: Mitochondrial uncoupling protein 2 gene transcript levels are elevated in maturating erythroid cells.
Volume: 581
Issue: 6
Pages: 1093-7
Publication
First Author: Yamada M
Year: 1998
Journal: FEBS Lett
Title: Genomic organization and promoter function of the mouse uncoupling protein 2 (UCP2) gene.
Volume: 432
Issue: 1-2
Pages: 65-9
Publication
First Author: Pecqueur C
Year: 2008
Journal: FASEB J
Title: Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization.
Volume: 22
Issue: 1
Pages: 9-18
Publication
First Author: Andrews ZB
Year: 2005
Journal: J Neurosci
Title: Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.
Volume: 25
Issue: 1
Pages: 184-91
Publication
First Author: Andrews ZB
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Uncoupling protein-2 regulates lifespan in mice.
Volume: 296
Issue: 4
Pages: E621-7
Publication
First Author: Wang Y
Year: 2010
Journal: FEBS Lett
Title: Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells.
Volume: 584
Issue: 8
Pages: 1503-8
Publication
First Author: Hodný Z
Year: 1998
Journal: FEBS Lett
Title: High expression of uncoupling protein 2 in foetal liver.
Volume: 425
Issue: 2
Pages: 185-90
Publication
First Author: Coppola A
Year: 2007
Journal: Cell Metab
Title: A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2.
Volume: 5
Issue: 1
Pages: 21-33
Publication
First Author: York B
Year: 1999
Journal: Mamm Genome
Title: Gene-environment interaction: a significant diet-dependent obesity locus demonstrated in a congenic segment on mouse chromosome 7.
Volume: 10
Issue: 5
Pages: 457-62
Publication
First Author: Robson-Doucette CA
Year: 2011
Journal: Diabetes
Title: Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion.
Volume: 60
Issue: 11
Pages: 2710-9
Publication
First Author: Arsenijevic D
Year: 2000
Journal: Nat Genet
Title: Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production.
Volume: 26
Issue: 4
Pages: 435-9
Publication
First Author: Couplan E
Year: 2002
Journal: J Biol Chem
Title: No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.
Volume: 277
Issue: 29
Pages: 26268-75
Publication
First Author: Tagen M
Year: 2009
Journal: J Immunol
Title: Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content.
Volume: 183
Issue: 10
Pages: 6313-9
Publication
First Author: Rupprecht A
Year: 2012
Journal: PLoS One
Title: Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation.
Volume: 7
Issue: 8
Pages: e41406
Publication
First Author: Moukdar F
Year: 2009
Journal: J Lipid Res
Title: Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice.
Volume: 50
Issue: 1
Pages: 59-70
Publication
First Author: Vogler S
Year: 2006
Journal: Am J Pathol
Title: Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis.
Volume: 168
Issue: 5
Pages: 1570-5
Publication
First Author: Chevillotte E
Year: 2007
Journal: Diabetes
Title: Uncoupling protein-2 controls adiponectin gene expression in adipose tissue through the modulation of reactive oxygen species production.
Volume: 56
Issue: 4
Pages: 1042-50
Publication
First Author: Dietrich MO
Year: 2008
Journal: J Neurosci
Title: Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation.
Volume: 28
Issue: 42
Pages: 10766-71
Publication
First Author: Andrews ZB
Year: 2010
Journal: Endocrinology
Title: Uncoupling protein-2 decreases the lipogenic actions of ghrelin.
Volume: 151
Issue: 5
Pages: 2078-86
Publication
First Author: Andrews ZB
Year: 2006
Journal: Eur J Neurosci
Title: Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function.
Volume: 24
Issue: 1
Pages: 32-6
Publication  
First Author: Sun XL
Year: 2011
Journal: Neuroscience
Title: Uncoupling protein 2 knockout exacerbates depression-like behaviors in mice via enhancing inflammatory response.
Volume: 192
Pages: 507-14
Publication
First Author: Zhou Y
Year: 2016
Journal: PLoS One
Title: PPARγ Inhibits VSMC Proliferation and Migration via Attenuating Oxidative Stress through Upregulating UCP2.
Volume: 11
Issue: 5
Pages: e0154720
Publication
First Author: Dromparis P
Year: 2013
Journal: Circ Res
Title: Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.
Volume: 113
Issue: 2
Pages: 126-36
Publication
First Author: Tian XY
Year: 2012
Journal: Circ Res
Title: Uncoupling protein-2 protects endothelial function in diet-induced obese mice.
Volume: 110
Issue: 9
Pages: 1211-6
Publication
First Author: Haslip M
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial uncoupling protein 2 regulates mitophagy and pulmonary hypertension during intermittent hypoxia.
Volume: 35
Issue: 5
Pages: 1166-78
Publication
First Author: Liu DQ
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Uncoupling protein-2 negatively regulates polymorphonuclear leukocytes chemotaxis via modulating [Ca2+] influx.
Volume: 30
Issue: 3
Pages: 575-81
Publication
First Author: Pi J
Year: 2009
Journal: Endocrinology
Title: Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function.
Volume: 150
Issue: 7
Pages: 3040-8
Publication
First Author: Krauss S
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2.
Volume: 99
Issue: 1
Pages: 118-22
Publication
First Author: Cao T
Year: 2013
Journal: Cell Immunol
Title: Mitochondrial uncoupling protein 2 protects splenocytes from oxidative stress-induced apoptosis during pathogen activation.
Volume: 286
Issue: 1-2
Pages: 39-44
Publication  
First Author: Chen K
Year: 2017
Journal: Sci Transl Med
Title: Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury.
Volume: 9
Issue: 418
Publication
First Author: Bodyak N
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes.
Volume: 293
Issue: 1
Pages: H829-35
Publication
First Author: Basu Ball W
Year: 2011
Journal: J Immunol
Title: Uncoupling protein 2 negatively regulates mitochondrial reactive oxygen species generation and induces phosphatase-mediated anti-inflammatory response in experimental visceral leishmaniasis.
Volume: 187
Issue: 3
Pages: 1322-32
Publication
First Author: Shimasaki Y
Year: 2013
Journal: Circ Res
Title: Uncoupling protein 2 impacts endothelial phenotype via p53-mediated control of mitochondrial dynamics.
Volume: 113
Issue: 7
Pages: 891-901
Publication
First Author: Zhang CY
Year: 2001
Journal: Cell
Title: Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.
Volume: 105
Issue: 6
Pages: 745-55
Publication
First Author: Echtay KS
Year: 2002
Journal: Nature
Title: Superoxide activates mitochondrial uncoupling proteins.
Volume: 415
Issue: 6867
Pages: 96-9
Publication
First Author: Chavin KD
Year: 1999
Journal: J Biol Chem
Title: Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion.
Volume: 274
Issue: 9
Pages: 5692-700
Publication
First Author: Affourtit C
Year: 2011
Journal: Free Radic Biol Med
Title: Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species.
Volume: 50
Issue: 5
Pages: 609-16
Publication  
First Author: Yoshitomi H
Year: 1999
Journal: Biochem J
Title: Mechanism of ubiquitous expression of mouse uncoupling protein 2 mRNA: control by cis-acting DNA element in 5'-flanking region.
Volume: 340 ( Pt 2)
Pages: 397-404
Publication
First Author: Hass DT
Year: 2019
Journal: J Neurosci
Title: Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma.
Volume: 39
Issue: 18
Pages: 3582-3596
Publication
First Author: Kuhla A
Year: 2011
Journal: Exp Gerontol
Title: Role of age and uncoupling protein-2 in oxidative stress, RAGE/AGE interaction and inflammatory liver injury.
Volume: 46
Issue: 11
Pages: 868-76
Publication
First Author: Joseph JW
Year: 2004
Journal: J Biol Chem
Title: Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
Volume: 279
Issue: 49
Pages: 51049-56
Publication
First Author: Kushi A
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice.
Volume: 95
Issue: 26
Pages: 15659-64
Publication
First Author: Parker N
Year: 2009
Journal: Biochim Biophys Acta
Title: Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.
Volume: 1787
Issue: 12
Pages: 1451-7
Publication
First Author: Vatamaniuk MZ
Year: 2006
Journal: Diabetes
Title: Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation.
Volume: 55
Issue: 10
Pages: 2730-6
Publication
First Author: Xu H
Year: 2015
Journal: Mol Cell Biol
Title: Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2.
Volume: 35
Issue: 6
Pages: 1055-65
Publication  
First Author: Steen KA
Year: 2017
Journal: Mol Cell Biol
Title: FABP4/aP2 Regulates Macrophage Redox Signaling and Inflammasome Activation via Control of UCP2.
Volume: 37
Issue: 2
Publication
First Author: Fleury C
Year: 1997
Journal: Nat Genet
Title: Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia.
Volume: 15
Issue: 3
Pages: 269-72
Publication
First Author: Gupta AK
Year: 2017
Journal: FASEB J
Title: Leishmania donovani inhibits inflammasome-dependent macrophage activation by exploiting the negative regulatory proteins A20 and UCP2.
Volume: 31
Issue: 11
Pages: 5087-5101
Publication
First Author: Kong D
Year: 2010
Journal: Cell Metab
Title: Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis.
Volume: 12
Issue: 5
Pages: 545-52
Publication
First Author: Kim JG
Year: 2015
Journal: Cell Rep
Title: AgRP Neurons Regulate Bone Mass.
Volume: 13
Issue: 1
Pages: 8-14
Publication
First Author: Liu Q
Year: 1998
Journal: Gene
Title: Uncoupling protein-3: a muscle-specific gene upregulated by leptin in ob/ob mice.
Volume: 207
Issue: 1
Pages: 1-7
Publication
First Author: Chen P
Year: 2009
Journal: Am J Pathol
Title: The protective role of Per2 against carbon tetrachloride-induced hepatotoxicity.
Volume: 174
Issue: 1
Pages: 63-70
Publication
First Author: Chen Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study.
Volume: 478
Issue: 1
Pages: 87-92
Publication
First Author: Lapp DW
Year: 2014
Journal: Glia
Title: Stat3 mediates LIF-induced protection of astrocytes against toxic ROS by upregulating the UPC2 mRNA pool.
Volume: 62
Issue: 2
Pages: 159-70
Publication
First Author: Hilse KE
Year: 2016
Journal: Biochim Biophys Acta
Title: The expression of UCP3 directly correlates to UCP1 abundance in brown adipose tissue.
Volume: 1857
Issue: 1
Pages: 72-78
Publication
First Author: Baffy G
Year: 2002
Journal: Hepatology
Title: Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2.
Volume: 35
Issue: 4
Pages: 753-61
Publication
First Author: Evans ZP
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Mitochondrial uncoupling protein-2 deficiency protects steatotic mouse hepatocytes from hypoxia/reoxygenation.
Volume: 302
Issue: 3
Pages: G336-42
Publication
First Author: Evans ZP
Year: 2008
Journal: J Biol Chem
Title: Mitochondrial uncoupling protein-2 mediates steatotic liver injury following ischemia/reperfusion.
Volume: 283
Issue: 13
Pages: 8573-9