Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4416460 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-15 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3564522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3825773 |
Age: |
embryonic day 14.5 |
Image: |
Additional file 4 Ucp2 |
|
Specimen Label: |
Additional file 4 Ucp2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li W |
Year: |
2015 |
Journal: |
Cancer Prev Res (Phila) |
Title: |
UCP2 knockout suppresses mouse skin carcinogenesis. |
Volume: |
8 |
Issue: |
6 |
Pages: |
487-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Broche B |
Year: |
2018 |
Journal: |
Diabetes |
Title: |
Mitochondrial Protein UCP2 Controls Pancreas Development. |
Volume: |
67 |
Issue: |
1 |
Pages: |
78-84 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
309
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
309
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Motloch LJ |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
By Regulating Mitochondrial Ca2+-Uptake UCP2 Modulates Intracellular Ca2+. |
Volume: |
11 |
Issue: |
2 |
Pages: |
e0148359 |
|
•
•
•
•
•
|
Publication |
First Author: |
NĂ¼bel T |
Year: |
2008 |
Journal: |
Biochim Biophys Acta |
Title: |
Modified glutamine catabolism in macrophages of Ucp2 knock-out mice. |
Volume: |
1777 |
Issue: |
1 |
Pages: |
48-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allister EM |
Year: |
2013 |
Journal: |
Diabetes |
Title: |
UCP2 regulates the glucagon response to fasting and starvation. |
Volume: |
62 |
Issue: |
5 |
Pages: |
1623-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Q |
Year: |
2023 |
Journal: |
Biochim Biophys Acta Mol Basis Dis |
Title: |
UCP2 deficiency impairs podocyte autophagy in diabetic nephropathy. |
Volume: |
1869 |
Issue: |
5 |
Pages: |
166705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JD |
Year: |
2019 |
Journal: |
Cell Metab |
Title: |
Microglial UCP2 Mediates Inflammation and Obesity Induced by High-Fat Feeding. |
Volume: |
30 |
Issue: |
5 |
Pages: |
952-962.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peixoto PM |
Year: |
2013 |
Journal: |
Mol Cell Neurosci |
Title: |
UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis. |
Volume: |
57 |
|
Pages: |
104-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Emre Y |
Year: |
2007 |
Journal: |
Biochem J |
Title: |
Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. |
Volume: |
402 |
Issue: |
2 |
Pages: |
271-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park D |
Year: |
2011 |
Journal: |
Nature |
Title: |
Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein. |
Volume: |
477 |
Issue: |
7363 |
Pages: |
220-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pan P |
Year: |
2018 |
Journal: |
Molecules |
Title: |
Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy. |
Volume: |
23 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
MĂ¼ller S |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice. |
Volume: |
9 |
Issue: |
4 |
Pages: |
e94494 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simon-Areces J |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e42911 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bordone L |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells. |
Volume: |
4 |
Issue: |
2 |
Pages: |
e31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dalgaard LT |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
UCP2 mRNA expression is dependent on glucose metabolism in pancreatic islets. |
Volume: |
417 |
Issue: |
1 |
Pages: |
495-500 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diao J |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival. |
Volume: |
105 |
Issue: |
33 |
Pages: |
12057-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berardi MJ |
Year: |
2014 |
Journal: |
Cell Metab |
Title: |
Fatty acid flippase activity of UCP2 is essential for its proton transport in mitochondria. |
Volume: |
20 |
Issue: |
3 |
Pages: |
541-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ji F |
Year: |
2017 |
Journal: |
Stem Cells |
Title: |
UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex. |
Volume: |
35 |
Issue: |
6 |
Pages: |
1479-1492 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haschemi A |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Carbon monoxide induced PPARγ SUMOylation and UCP2 block inflammatory gene expression in macrophages. |
Volume: |
6 |
Issue: |
10 |
Pages: |
e26376 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rigaud VO |
Year: |
2022 |
Journal: |
JCI Insight |
Title: |
UCP2 modulates cardiomyocyte cell cycle activity, acetyl-CoA, and histone acetylation in response to moderate hypoxia. |
Volume: |
7 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Y |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
UCP2 attenuates apoptosis of tubular epithelial cells in renal ischemia-reperfusion injury. |
Volume: |
313 |
Issue: |
4 |
Pages: |
F926-F937 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varela L |
Year: |
2016 |
Journal: |
Neurobiol Dis |
Title: |
Mitochondria controlled by UCP2 determine hypoxia-induced synaptic remodeling in the cortex and hippocampus. |
Volume: |
90 |
|
Pages: |
68-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2022 |
Journal: |
Adv Sci (Weinh) |
Title: |
Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development. |
Volume: |
9 |
Issue: |
18 |
Pages: |
e2105208 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maes ME |
Year: |
2023 |
Journal: |
iScience |
Title: |
Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout. |
Volume: |
26 |
Issue: |
10 |
Pages: |
107780 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aguilar E |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses. |
Volume: |
28 |
Issue: |
9 |
Pages: |
2306-2316.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Q |
Year: |
2023 |
Journal: |
FASEB J |
Title: |
Loss of UCP2 causes mitochondrial fragmentation by OMA1-dependent proteolytic processing of OPA1 in podocytes. |
Volume: |
37 |
Issue: |
11 |
Pages: |
e23265 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hong J |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
15449 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kukat A |
Year: |
2014 |
Journal: |
PLoS Genet |
Title: |
Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e1004385 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou M |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K. |
Volume: |
7 |
Issue: |
2 |
Pages: |
e32349 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Bilbao F |
Year: |
2004 |
Journal: |
J Neurochem |
Title: |
Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels. |
Volume: |
89 |
Issue: |
5 |
Pages: |
1283-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuboyama-Kasaoka N |
Year: |
2008 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Studies of UCP2 transgenic and knockout mice reveal that liver UCP2 is not essential for the antiobesity effects of fish oil. |
Volume: |
294 |
Issue: |
3 |
Pages: |
E600-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alves-Guerra MC |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Analysis of uncoupling protein 2-deficient mice upon anaesthesia and sedation revealed a role for UCP2 in locomotion. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e41846 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang D |
Year: |
2014 |
Journal: |
Neuroscience |
Title: |
Hippocampal UCP2 is essential for cognition and resistance to anxiety but not required for the benefits of exercise. |
Volume: |
277 |
|
Pages: |
36-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toda C |
Year: |
2016 |
Journal: |
Cell |
Title: |
UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness. |
Volume: |
164 |
Issue: |
5 |
Pages: |
872-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aheng C |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Deletion of UCP2 in iNOS deficient mice reduces the severity of the disease during experimental autoimmune encephalomyelitis. |
Volume: |
6 |
Issue: |
8 |
Pages: |
e22841 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caron A |
Year: |
2017 |
Journal: |
Biochimie |
Title: |
Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue. |
Volume: |
134 |
|
Pages: |
118-126 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrews ZB |
Year: |
2008 |
Journal: |
Nature |
Title: |
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. |
Volume: |
454 |
Issue: |
7206 |
Pages: |
846-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Emre Y |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes. |
Volume: |
104 |
Issue: |
48 |
Pages: |
19085-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elorza A |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis. |
Volume: |
283 |
Issue: |
45 |
Pages: |
30461-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oh KS |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Liver PPARalpha and UCP2 are involved in the regulation of obesity and lipid metabolism by swim training in genetically obese db/db mice. |
Volume: |
345 |
Issue: |
3 |
Pages: |
1232-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diano S |
Year: |
2003 |
Journal: |
Endocrinology |
Title: |
Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning. |
Volume: |
144 |
Issue: |
11 |
Pages: |
5014-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haines B |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Overexpression of mitochondrial uncoupling protein 2 inhibits inflammatory cytokines and activates cell survival factors after cerebral ischemia. |
Volume: |
7 |
Issue: |
2 |
Pages: |
e31739 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnstable CJ |
Year: |
2016 |
Journal: |
J Mol Neurosci |
Title: |
Mitochondrial Uncoupling Protein 2 (UCP2) Regulates Retinal Ganglion Cell Number and Survival. |
Volume: |
58 |
Issue: |
4 |
Pages: |
461-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrews ZB |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. |
Volume: |
25 |
Issue: |
1 |
Pages: |
184-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horvath B |
Year: |
2002 |
Journal: |
Biochem Pharmacol |
Title: |
Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. |
Volume: |
64 |
Issue: |
3 |
Pages: |
369-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mattiasson G |
Year: |
2003 |
Journal: |
Nat Med |
Title: |
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. |
Volume: |
9 |
Issue: |
8 |
Pages: |
1062-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
McDonald RB |
Year: |
2008 |
Journal: |
Exp Gerontol |
Title: |
Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice. |
Volume: |
43 |
Issue: |
12 |
Pages: |
1061-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asami DK |
Year: |
2008 |
Journal: |
Exp Gerontol |
Title: |
Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice. |
Volume: |
43 |
Issue: |
12 |
Pages: |
1069-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horvath TL |
Year: |
2003 |
Journal: |
Int J Obes Relat Metab Disord |
Title: |
Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice. |
Volume: |
27 |
Issue: |
4 |
Pages: |
433-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ozcan C |
Year: |
2013 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Role of uncoupling protein 3 in ischemia-reperfusion injury, arrhythmias, and preconditioning. |
Volume: |
304 |
Issue: |
9 |
Pages: |
H1192-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suski JM |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: new evidence for a putative novel function of uncoupling proteins as superoxide anion transporters. |
Volume: |
428 |
Issue: |
2 |
Pages: |
234-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirose M |
Year: |
2018 |
Journal: |
Mitochondrion |
Title: |
The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice. |
Volume: |
42 |
|
Pages: |
50-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flachs P |
Year: |
2007 |
Journal: |
FEBS Lett |
Title: |
Mitochondrial uncoupling protein 2 gene transcript levels are elevated in maturating erythroid cells. |
Volume: |
581 |
Issue: |
6 |
Pages: |
1093-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamada M |
Year: |
1998 |
Journal: |
FEBS Lett |
Title: |
Genomic organization and promoter function of the mouse uncoupling protein 2 (UCP2) gene. |
Volume: |
432 |
Issue: |
1-2 |
Pages: |
65-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pecqueur C |
Year: |
2008 |
Journal: |
FASEB J |
Title: |
Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization. |
Volume: |
22 |
Issue: |
1 |
Pages: |
9-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrews ZB |
Year: |
2009 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Uncoupling protein-2 regulates lifespan in mice. |
Volume: |
296 |
Issue: |
4 |
Pages: |
E621-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2010 |
Journal: |
FEBS Lett |
Title: |
Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells. |
Volume: |
584 |
Issue: |
8 |
Pages: |
1503-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coppola A |
Year: |
2007 |
Journal: |
Cell Metab |
Title: |
A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. |
Volume: |
5 |
Issue: |
1 |
Pages: |
21-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoon NA |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
UCP2-dependent redox sensing in POMC neurons regulates feeding. |
Volume: |
41 |
Issue: |
13 |
Pages: |
111894 |
|
•
•
•
•
•
|
Publication |
First Author: |
York B |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
Gene-environment interaction: a significant diet-dependent obesity locus demonstrated in a congenic segment on mouse chromosome 7. |
Volume: |
10 |
Issue: |
5 |
Pages: |
457-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robson-Doucette CA |
Year: |
2011 |
Journal: |
Diabetes |
Title: |
Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion. |
Volume: |
60 |
Issue: |
11 |
Pages: |
2710-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arsenijevic D |
Year: |
2000 |
Journal: |
Nat Genet |
Title: |
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. |
Volume: |
26 |
Issue: |
4 |
Pages: |
435-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Couplan E |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria. |
Volume: |
277 |
Issue: |
29 |
Pages: |
26268-75 |
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Publication |
First Author: |
Rupprecht A |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e41406 |
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Publication |
First Author: |
Chevillotte E |
Year: |
2007 |
Journal: |
Diabetes |
Title: |
Uncoupling protein-2 controls adiponectin gene expression in adipose tissue through the modulation of reactive oxygen species production. |
Volume: |
56 |
Issue: |
4 |
Pages: |
1042-50 |
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Publication |
First Author: |
Vogler S |
Year: |
2006 |
Journal: |
Am J Pathol |
Title: |
Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis. |
Volume: |
168 |
Issue: |
5 |
Pages: |
1570-5 |
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Publication |
First Author: |
Moukdar F |
Year: |
2009 |
Journal: |
J Lipid Res |
Title: |
Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice. |
Volume: |
50 |
Issue: |
1 |
Pages: |
59-70 |
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Publication |
First Author: |
Tagen M |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content. |
Volume: |
183 |
Issue: |
10 |
Pages: |
6313-9 |
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Publication |
First Author: |
Sun XL |
Year: |
2011 |
Journal: |
Neuroscience |
Title: |
Uncoupling protein 2 knockout exacerbates depression-like behaviors in mice via enhancing inflammatory response. |
Volume: |
192 |
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Pages: |
507-14 |
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Publication |
First Author: |
Chen K |
Year: |
2017 |
Journal: |
Sci Transl Med |
Title: |
Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury. |
Volume: |
9 |
Issue: |
418 |
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Publication |
First Author: |
Zhou Y |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
PPARγ Inhibits VSMC Proliferation and Migration via Attenuating Oxidative Stress through Upregulating UCP2. |
Volume: |
11 |
Issue: |
5 |
Pages: |
e0154720 |
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Publication |
First Author: |
Cao T |
Year: |
2013 |
Journal: |
Cell Immunol |
Title: |
Mitochondrial uncoupling protein 2 protects splenocytes from oxidative stress-induced apoptosis during pathogen activation. |
Volume: |
286 |
Issue: |
1-2 |
Pages: |
39-44 |
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Publication |
First Author: |
Tian XY |
Year: |
2012 |
Journal: |
Circ Res |
Title: |
Uncoupling protein-2 protects endothelial function in diet-induced obese mice. |
Volume: |
110 |
Issue: |
9 |
Pages: |
1211-6 |
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Publication |
First Author: |
Haslip M |
Year: |
2015 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Endothelial uncoupling protein 2 regulates mitophagy and pulmonary hypertension during intermittent hypoxia. |
Volume: |
35 |
Issue: |
5 |
Pages: |
1166-78 |
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Publication |
First Author: |
Dromparis P |
Year: |
2013 |
Journal: |
Circ Res |
Title: |
Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension. |
Volume: |
113 |
Issue: |
2 |
Pages: |
126-36 |
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Publication |
First Author: |
Pi J |
Year: |
2009 |
Journal: |
Endocrinology |
Title: |
Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function. |
Volume: |
150 |
Issue: |
7 |
Pages: |
3040-8 |
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Publication |
First Author: |
Jiang L |
Year: |
2013 |
Journal: |
Kidney Int |
Title: |
A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis. |
Volume: |
84 |
Issue: |
2 |
Pages: |
285-96 |
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Publication |
First Author: |
Krauss S |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2. |
Volume: |
99 |
Issue: |
1 |
Pages: |
118-22 |
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Publication |
First Author: |
Andrews ZB |
Year: |
2010 |
Journal: |
Endocrinology |
Title: |
Uncoupling protein-2 decreases the lipogenic actions of ghrelin. |
Volume: |
151 |
Issue: |
5 |
Pages: |
2078-86 |
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Publication |
First Author: |
Andrews ZB |
Year: |
2006 |
Journal: |
Eur J Neurosci |
Title: |
Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function. |
Volume: |
24 |
Issue: |
1 |
Pages: |
32-6 |
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Publication |
First Author: |
Dietrich MO |
Year: |
2008 |
Journal: |
J Neurosci |
Title: |
Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation. |
Volume: |
28 |
Issue: |
42 |
Pages: |
10766-71 |
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Publication |
First Author: |
Liu DQ |
Year: |
2010 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Uncoupling protein-2 negatively regulates polymorphonuclear leukocytes chemotaxis via modulating [Ca2+] influx. |
Volume: |
30 |
Issue: |
3 |
Pages: |
575-81 |
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Publication |
First Author: |
Emin MT |
Year: |
2023 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Mitochondria of lung venular capillaries mediate lung-liver cross talk in pneumonia. |
Volume: |
325 |
Issue: |
3 |
Pages: |
L277-L287 |
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Publication |
First Author: |
Bodyak N |
Year: |
2007 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes. |
Volume: |
293 |
Issue: |
1 |
Pages: |
H829-35 |
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Publication |
First Author: |
Basu Ball W |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Uncoupling protein 2 negatively regulates mitochondrial reactive oxygen species generation and induces phosphatase-mediated anti-inflammatory response in experimental visceral leishmaniasis. |
Volume: |
187 |
Issue: |
3 |
Pages: |
1322-32 |
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Publication |
First Author: |
Zhang Y |
Year: |
2019 |
Journal: |
Mol Membr Biol |
Title: |
Uncoupling protein 2 prevents ischaemia reperfusion injury through the regulation ROS/NF-κB signalling in mice. |
Volume: |
35 |
Issue: |
1 |
Pages: |
51-59 |
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Publication |
First Author: |
Ke Q |
Year: |
2020 |
Journal: |
Cell Death Dis |
Title: |
UCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury. |
Volume: |
11 |
Issue: |
1 |
Pages: |
26 |
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Publication |
First Author: |
Zhang Y |
Year: |
2017 |
Journal: |
J Am Heart Assoc |
Title: |
Uncoupling Protein 2 Inhibits Myointimal Hyperplasia in Preclinical Animal Models of Vascular Injury. |
Volume: |
6 |
Issue: |
10 |
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