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Search results 1 to 99 out of 99 for Ufc1

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
51506 | UFC1
Type: gene
Organism: human
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Gene
537221 | UFC1
Type: gene
Organism: cattle
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Gene
445256 | ufc1
Type: gene
Organism: zebrafish
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Gene
720277 | UFC1
Type: gene
Organism: macaque, rhesus
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Gene
100125147 | ufc1
Type: gene
Organism: frog, western clawed
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Gene
107057454 | UFC1
Type: gene
Organism: chicken
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Gene
445268 | Ufc1
Type: gene
Organism: rat
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Gene
478978 | UFC1
Type: gene
Organism: dog, domestic
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Gene
457449 | UFC1
Type: gene
Organism: chimpanzee
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Protein Domain
IPR014806 | Ufc1
Type: Family
Description: Ubiquitin-like (UBL) post-translational modifiers are covalently linked to most, if not all, target protein(s) through an enzymatic cascade analogous to ubiquitylation, consisting of E1 (activating), E2 (conjugating), and E3 (ligating) enzymes. Ubiquitin-fold modifier 1 (Ufm1) a ubiquitin-like protein is activated by a novel E1-like enzyme, Uba5, by forming a high-energy thioester bond. Activated Ufm1 is then transferred to its cognate E2-like enzyme, Ufc1, in a similar thioester linkage. This family represents the E2-like enzyme which catalyses the second step in ufmylation [, ].
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Protein Coding Gene
MGI:1913405 | Ufc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100124402 | UFC1P1
Type: gene
Organism: human
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Publication
29868776 | -
First Author: Nahorski MS
Year: 2018
Journal: Brain
Title: Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development.
Volume: 141
Issue: 7
Pages: 1934-1945
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Publication
15071506 | -
First Author: Komatsu M
Year: 2004
Journal: EMBO J
Title: A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
Volume: 23
Issue: 9
Pages: 1977-86
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Protein
Q9CR09
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: false
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Protein
M0QWS4
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0014864 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016493 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016671 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017193 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028102 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015669 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423432
Age: embryonic day 16.5
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423432
Age: embryonic day 16.5
Image: 6
Specimen Label: WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423432
Age: embryonic day 16.5
Image: 6
Specimen Label: KO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:6423432
Age: embryonic day 16.5
Image: 6
Specimen Label: KO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423441
Age: postnatal month 1
Image: S6
Specimen Label: Con
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423441
Age: postnatal month 1
Image: S6
Specimen Label: Con
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423441
Age: postnatal month 1
Image: S6
Specimen Label: CKO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6423137
Assay Type: Western blot
Annotation Date: 2020-05-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6423441
Age: postnatal month 1
Image: S6
Specimen Label: CKO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_01
Specimen Label: euxassay_000654_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_02
Specimen Label: euxassay_000654_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_03
Specimen Label: euxassay_000654_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_04
Specimen Label: euxassay_000654_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_05
Specimen Label: euxassay_000654_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_06
Specimen Label: euxassay_000654_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_21
Specimen Label: euxassay_000654_21
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_22
Specimen Label: euxassay_000654_22
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:979456
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829074
Age: embryonic day 14.5
Image: euxassay_000654_23
Specimen Label: euxassay_000654_23
Detected: true
Specimen Num: 9
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Publication
- | J:76287
   
First Author: Steinebrunner I
Year: 1998
Journal: GenBank Submission
Title: Mus musculus unknown mRNA, clone C20.3
Pages: Y17677
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Publication
23152784 | J:195351
First Author: Zhang Y
Year: 2012
Journal: PLoS One
Title: Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Volume: 7
Issue: 11
Pages: e48587
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Publication
30635284 | J:272566
 
First Author: Yang R
Year: 2019
Journal: Development
Title: CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Volume: 146
Issue: 2
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Publication
10051400 | J:52606
First Author: Eddleston J
Year: 1999
Journal: Genomics
Title: Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp).
Volume: 56
Issue: 2
Pages: 149-59
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Publication
11591653 | J:103507
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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DO Term
DOID:0070421 | neurodevelopmental disorder with spasticity and poor growth
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Publication
10884686 | -
First Author: Jentsch S
Year: 2000
Journal: Trends Cell Biol
Title: Ubiquitin and its kin: how close are the family ties?
Volume: 10
Issue: 8
Pages: 335-42
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Publication
16527251 | -
First Author: Sasakawa H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1.
Volume: 343
Issue: 1
Pages: 21-6
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Protein Domain
IPR005375 | UFM1
Type: Family
Description: This entry represents Ufm1 (ubiquitin-fold modifier), which is a ubiquitin-like protein with structural similarities to ubiquitin [, ]. Ufm1 is one of a number of ubiquitin-like modifiers that conjugate to target proteins in cells through Uba5 (E1) and Ufc1 (E2). The Ufm1-system is conserved in metazoa and plants, suggesting it has a potential role in multicellular organisms []. Human Ufm1 is synthesized as a precursor consisting of 85 amino-acid residues. Prior to activation by Uba5, the extra amino acids at the C-terminal region of Ufm1 are removed to expose Gly, which is necessary for conjugation to target molecule(s). C-terminal processing of Ufm1 requires two specific cysteine peptidases (): UfSP1 and UfSP2; both peptidases are also able to release Ufm1 from Ufm1-conjugated cellular proteins. UfSP2 is present in most, if not all, of multi-cellular organisms including plant, nematode, fly, and mammal, whereas UfSP1 is not present in plants and nematodes [].
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Publication
30701081 | J:298771
 
First Author: Cai Y
Year: 2019
Journal: Cell Discov
Title: Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation.
Volume: 5
Pages: 7
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Publication
25952549 | J:238253
First Author: Zhang M
Year: 2015
Journal: Cell Death Differ
Title: RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis.
Volume: 22
Issue: 12
Pages: 1922-34
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Publication
34148841 | J:333688
First Author: Zhou Y
Year: 2021
Journal: J Genet Genomics
Title: Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis.
Volume: 48
Issue: 5
Pages: 403-410
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Protein
P61961
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
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Protein
D3YW97
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
H7BWZ1
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: false
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Publication
26544067 | J:231701
First Author: Cai Y
Year: 2015
Journal: PLoS Genet
Title: UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development.
Volume: 11
Issue: 11
Pages: e1005643
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Publication
17182609 | J:120365
First Author: Kang SH
Year: 2007
Journal: J Biol Chem
Title: Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2.
Volume: 282
Issue: 8
Pages: 5256-62
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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