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Search results 1 to 100 out of 462 for Ufm1

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
51569 | UFM1
Type: gene
Organism: human
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Gene
452546 | UFM1
Type: gene
Organism: chimpanzee
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Gene
530547 | UFM1
Type: gene
Organism: cattle
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Gene
418894 | UFM1
Type: gene
Organism: chicken
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Gene
322756 | ufm1
Type: gene
Organism: zebrafish
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Gene
695866 | UFM1
Type: gene
Organism: macaque, rhesus
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Gene
549742 | ufm1
Type: gene
Organism: frog, western clawed
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Gene
365797 | Ufm1
Type: gene
Organism: rat
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Gene
477297 | UFM1
Type: gene
Organism: dog, domestic
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Protein Domain
IPR005375 | UFM1
Type: Family
Description: This entry represents Ufm1 (ubiquitin-fold modifier), which is a ubiquitin-like protein with structural similarities to ubiquitin [, ]. Ufm1 is one of a number of ubiquitin-like modifiers that conjugate to target proteins in cells through Uba5 (E1) and Ufc1 (E2). The Ufm1-system is conserved in metazoa and plants, suggesting it has a potential role in multicellular organisms []. Human Ufm1 is synthesized as a precursor consisting of 85 amino-acid residues. Prior to activation by Uba5, the extra amino acids at the C-terminal region of Ufm1 are removed to expose Gly, which is necessary for conjugation to target molecule(s). C-terminal processing of Ufm1 requires two specific cysteine peptidases (): UfSP1 and UfSP2; both peptidases are also able to release Ufm1 from Ufm1-conjugated cellular proteins. UfSP2 is present in most, if not all, of multi-cellular organisms including plant, nematode, fly, and mammal, whereas UfSP1 is not present in plants and nematodes [].
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Protein Coding Gene
MGI:1915140 | Ufm1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:4417209
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826113
Age: embryonic day 14.5
Image: Additional file 4 Ufm1
Specimen Label: Additional file 4 Ufm1
Detected: true
Specimen Num: 1
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Publication
18321862 | J:138582
First Author: Ha BH
Year: 2008
Journal: J Biol Chem
Title: Structural basis for Ufm1 processing by UfSP1.
Volume: 283
Issue: 21
Pages: 14893-900
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Publication
20018847 | J:158995
First Author: Tatsumi K
Year: 2010
Journal: J Biol Chem
Title: A novel type of E3 ligase for the Ufm1 conjugation system.
Volume: 285
Issue: 8
Pages: 5417-27
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Gene
729835 | UFM1P2
Type: gene
Organism: human
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Gene
100506633 | UFM1P3
Type: gene
Organism: human
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Gene
102443352 | UFM1P1
Type: gene
Organism: human
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Publication
23152784 | J:195351
First Author: Zhang Y
Year: 2012
Journal: PLoS One
Title: Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Volume: 7
Issue: 11
Pages: e48587
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Gene
55325 | UFSP2
Type: gene
Organism: human
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Gene
23376 | UFL1
Type: gene
Organism: human
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Publication
17182609 | J:120365
First Author: Kang SH
Year: 2007
Journal: J Biol Chem
Title: Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2.
Volume: 282
Issue: 8
Pages: 5256-62
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Publication
10884686 | -
First Author: Jentsch S
Year: 2000
Journal: Trends Cell Biol
Title: Ubiquitin and its kin: how close are the family ties?
Volume: 10
Issue: 8
Pages: 335-42
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Publication
16527251 | -
First Author: Sasakawa H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1.
Volume: 343
Issue: 1
Pages: 21-6
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Protein
P61961
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
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Protein
D3YW97
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
H7BWZ1
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: false
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Publication
15071506 | -
First Author: Komatsu M
Year: 2004
Journal: EMBO J
Title: A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
Volume: 23
Issue: 9
Pages: 1977-86
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Gene
402682 | UFSP1
Type: gene
Organism: human
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Publication
27545674 | J:240522
First Author: Muona M
Year: 2016
Journal: Am J Hum Genet
Title: Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy.
Volume: 99
Issue: 3
Pages: 683-694
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Publication
21494687 | J:217277
First Author: Lemaire K
Year: 2011
Journal: PLoS One
Title: Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.
Volume: 6
Issue: 4
Pages: e18517
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Publication
31829413 | J:298551
 
First Author: Hu X
Year: 2020
Journal: Biosci Rep
Title: Ubiquitin fold modifier 1 activates NF-κB pathway by down-regulating LZAP expression in the macrophage of diabetic mouse model.
Volume: 40
Issue: 1
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Protein Coding Gene
MGP_CAROLIEiJ_G0024987 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026925 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027686 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026451 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026428 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025922 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6454282
Assay Type: RT-PCR
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6454299
Age: embryonic day 15.5
Image: S7
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6454282
Assay Type: RT-PCR
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6454299
Age: embryonic day 15.5
Image: S7
Specimen Label: my/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6454282
Assay Type: RT-PCR
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6454299
Age: embryonic day 15.5
Image: S7
Specimen Label: my/my
Detected: true
Specimen Num: 3
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Publication
33372156 | J:300137
 
First Author: Balce DR
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages.
Volume: 118
Issue: 1
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Publication
16880404 | J:111788
First Author: Kiyozumi D
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.
Volume: 103
Issue: 32
Pages: 11981-6
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Publication
29632206 | J:261328
First Author: Zou J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Volume: 115
Issue: 17
Pages: E4101-E4110
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Protein Coding Gene
MGI:1914740 | Ufl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
25952549 | J:238253
First Author: Zhang M
Year: 2015
Journal: Cell Death Differ
Title: RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis.
Volume: 22
Issue: 12
Pages: 1922-34
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GO Term
GO:0071567 | deUFMylase activity
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Publication
36120581 | J:333491
 
First Author: Wang K
Year: 2022
Journal: Front Cell Dev Biol
Title: Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1.
Volume: 10
Pages: 961675
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Gene
474999 | UFL1
Type: gene
Organism: dog, domestic
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Gene
482908 | UFSP2
Type: gene
Organism: dog, domestic
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Gene
461636 | UFSP2
Type: gene
Organism: chimpanzee
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Gene
462889 | UFL1
Type: gene
Organism: chimpanzee
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Gene
515894 | UFL1
Type: gene
Organism: cattle
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Gene
617788 | UFSP2
Type: gene
Organism: cattle
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Gene
421804 | UFL1
Type: gene
Organism: chicken
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Gene
422542 | UFSP2
Type: gene
Organism: chicken
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Gene
699794 | UFSP2
Type: gene
Organism: macaque, rhesus
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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