Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang SH |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. |
Volume: |
282 |
Issue: |
8 |
Pages: |
5256-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ha BH |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Structure of ubiquitin-fold modifier 1-specific protease UfSP2. |
Volume: |
286 |
Issue: |
12 |
Pages: |
10248-57 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
461
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6423437 |
Age: |
embryonic day 16.5 |
Image: |
6 |
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6423437 |
Age: |
embryonic day 16.5 |
Image: |
6 |
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6423437 |
Age: |
embryonic day 16.5 |
Image: |
6 |
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6423437 |
Age: |
embryonic day 16.5 |
Image: |
6 |
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6423445 |
Age: |
postnatal month 1 |
Image: |
S6 |
|
Specimen Label: |
Con |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6423445 |
Age: |
postnatal month 1 |
Image: |
S6 |
|
Specimen Label: |
Con |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6423445 |
Age: |
postnatal month 1 |
Image: |
S6 |
|
Specimen Label: |
CKO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6423141 |
Assay Type: |
Western blot |
Annotation Date: |
2020-05-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6423445 |
Age: |
postnatal month 1 |
Image: |
S6 |
|
Specimen Label: |
CKO |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-15 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3564522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3826138 |
Age: |
embryonic day 14.5 |
Image: |
Additional file 4 1810047C23Rik |
|
Specimen Label: |
Additional file 4 1810047C23Rik |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_01 |
|
Specimen Label: |
euxassay_002185_01 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_02 |
|
Specimen Label: |
euxassay_002185_02 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_03 |
|
Specimen Label: |
euxassay_002185_03 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_04 |
|
Specimen Label: |
euxassay_002185_04 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_05 |
|
Specimen Label: |
euxassay_002185_05 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_06 |
|
Specimen Label: |
euxassay_002185_06 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_07 |
|
Specimen Label: |
euxassay_002185_07 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_18 |
|
Specimen Label: |
euxassay_002185_18 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_19 |
|
Specimen Label: |
euxassay_002185_19 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_20 |
|
Specimen Label: |
euxassay_002185_20 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_21 |
|
Specimen Label: |
euxassay_002185_21 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_22 |
|
Specimen Label: |
euxassay_002185_22 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3589023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_07 |
|
Specimen Label: |
euxassay_002185_07 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3589023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_08 |
|
Specimen Label: |
euxassay_002185_08 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3589023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_09 |
|
Specimen Label: |
euxassay_002185_09 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3589023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_16 |
|
Specimen Label: |
euxassay_002185_16 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1373240 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3589023 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4829077 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_002185_18 |
|
Specimen Label: |
euxassay_002185_18 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ha BH |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Structural basis for Ufm1 processing by UfSP1. |
Volume: |
283 |
Issue: |
21 |
Pages: |
14893-900 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balce DR |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages. |
Volume: |
118 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yang R |
Year: |
2019 |
Journal: |
Development |
Title: |
CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. |
Volume: |
146 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hoffman BG |
Year: |
2008 |
Journal: |
Genome Biol |
Title: |
Identification of transcripts with enriched expression in the developing and adult pancreas. |
Volume: |
9 |
Issue: |
6 |
Pages: |
R99 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Publication |
First Author: |
GOA curators |
Year: |
2016 |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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DO Term |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
191
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
 |
Fragment?: |
false |
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Protein Domain |
Type: |
Family |
Description: |
This entry contains UfSP1 and UfSP2, which are cysteine peptidases required for the processing and activation of Ubiquitin fold modifier 1 (Ufm1, ) and for its release from conjugated cellular proteins. UfSP1 and UfSP2 are 217 aa and 461 aa respectively [, ]. The peptidases belong to MEROPS peptidase family C78, clan CA. The UfSP2 family have an N-terminal extension with one or more zinc finger domains of the C2H2 type, which have been shown to be involved in protein:protein interaction. UfSP2 is present in most, if not all, multi-cellular organisms including plants, nematodes, flies, and mammals, whereas UfSP1 is not present in plants and nematodes []. |
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DO Term |
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Publication |
First Author: |
Komatsu M |
Year: |
2004 |
Journal: |
EMBO J |
Title: |
A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier. |
Volume: |
23 |
Issue: |
9 |
Pages: |
1977-86 |
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Publication |
First Author: |
Yoo HM |
Year: |
2014 |
Journal: |
Mol Cell |
Title: |
Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development. |
Volume: |
56 |
Issue: |
2 |
Pages: |
261-74 |
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Publication |
First Author: |
Zhou J |
Year: |
2023 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Dysregulation of PD-L1 by UFMylation imparts tumor immune evasion and identified as a potential therapeutic target. |
Volume: |
120 |
Issue: |
11 |
Pages: |
e2215732120 |
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Publication |
First Author: |
Jentsch S |
Year: |
2000 |
Journal: |
Trends Cell Biol |
Title: |
Ubiquitin and its kin: how close are the family ties? |
Volume: |
10 |
Issue: |
8 |
Pages: |
335-42 |
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Publication |
First Author: |
Sasakawa H |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1. |
Volume: |
343 |
Issue: |
1 |
Pages: |
21-6 |
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Protein Domain |
Type: |
Family |
Description: |
This entry represents Ufm1 (ubiquitin-fold modifier), which is a ubiquitin-like protein with structural similarities to ubiquitin [, ]. Ufm1 is one of a number of ubiquitin-like modifiers that conjugate to target proteins in cells through Uba5 (E1) and Ufc1 (E2). The Ufm1-system is conserved in metazoa and plants, suggesting it has a potential role in multicellular organisms []. Human Ufm1 is synthesized as a precursor consisting of 85 amino-acid residues. Prior to activation by Uba5, the extra amino acids at the C-terminal region of Ufm1 are removed to expose Gly, which is necessary for conjugation to target molecule(s). C-terminal processing of Ufm1 requires two specific cysteine peptidases (): UfSP1 and UfSP2; both peptidases are also able to release Ufm1 from Ufm1-conjugated cellular proteins. UfSP2 is present in most, if not all, of multi-cellular organisms including plant, nematode, fly, and mammal, whereas UfSP1 is not present in plants and nematodes []. |
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