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Search results 1 to 100 out of 686 for Uhrf1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
455613 | UHRF1
Type: gene
Organism: chimpanzee
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Gene
611463 | UHRF1
Type: gene
Organism: dog, domestic
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Gene
530411 | UHRF1
Type: gene
Organism: cattle
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Gene
420154 | UHRF1
Type: gene
Organism: chicken
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Gene
406350 | uhrf1
Type: gene
Organism: zebrafish
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Gene
695531 | UHRF1
Type: gene
Organism: macaque, rhesus
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Gene
100491405 | uhrf1
Type: gene
Organism: frog, western clawed
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Gene
29128 | UHRF1
Type: gene
Organism: human
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Gene
316129 | Uhrf1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1338889 | Uhrf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21489993 | J:190276
First Author: Nady N
Year: 2011
Journal: J Biol Chem
Title: Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
Volume: 286
Issue: 27
Pages: 24300-11
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Publication
17673620 | J:188898
First Author: Bostick M
Year: 2007
Journal: Science
Title: UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
Volume: 317
Issue: 5845
Pages: 1760-4
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Publication
19056828 | J:173043
First Author: Kim JK
Year: 2009
Journal: Nucleic Acids Res
Title: UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.
Volume: 37
Issue: 2
Pages: 493-505
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Publication
21268065 | J:188893
First Author: Qin W
Year: 2011
Journal: J Cell Biochem
Title: Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1.
Volume: 112
Issue: 2
Pages: 439-44
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Publication
29999568 | J:268380
First Author: Blanchart A
Year: 2018
Journal: Stem Cells
Title: UHRF1 Licensed Self-Renewal of Active Adult Neural Stem Cells.
Volume: 36
Issue: 11
Pages: 1736-1751
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Publication
35243267 | J:321637
First Author: Sakai H
Year: 2022
Journal: iScience
Title: Uhrf1 governs the proliferation and differentiation of muscle satellite cells.
Volume: 25
Issue: 3
Pages: 103928
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Publication
29558369 | J:262715
First Author: Elia L
Year: 2018
Journal: J Clin Invest
Title: UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease.
Volume: 128
Issue: 6
Pages: 2473-2486
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Publication
37407562 | J:337993
First Author: Kostyrko K
Year: 2023
Journal: Nat Commun
Title: UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma.
Volume: 14
Issue: 1
Pages: 3966
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Publication
35905740 | J:344109
First Author: Zhou S
Year: 2022
Journal: Stem Cell Reports
Title: UHRF1 interacts with snRNAs and regulates alternative splicing in mouse spermatogonial stem cells.
Volume: 17
Issue: 8
Pages: 1859-1873
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Publication
27050515 | J:234945
First Author: Cui Y
Year: 2016
Journal: Cell Rep
Title: Uhrf1 Controls iNKT Cell Survival and Differentiation through the Akt-mTOR Axis.
Volume: 15
Issue: 2
Pages: 256-63
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Publication
32358021 | J:294658
First Author: Zhang Y
Year: 2020
Journal: J Immunol
Title: UHRF1 Controls Thymocyte Fate Decisions through the Epigenetic Regulation of EGR1 Expression.
Volume: 204
Issue: 12
Pages: 3248-3261
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Publication
35440090 | J:324178
First Author: Wu Y
Year: 2022
Journal: Cell Death Dis
Title: UHRF1 establishes crosstalk between somatic and germ cells in male reproduction.
Volume: 13
Issue: 4
Pages: 377
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Publication
29180567 | J:254128
 
First Author: Yamashita M
Year: 2018
Journal: Development
Title: Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression.
Volume: 145
Issue: 1
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Publication
29618490 | J:261586
First Author: Chen C
Year: 2018
Journal: J Exp Med
Title: Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection.
Volume: 215
Issue: 5
Pages: 1437-1448
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Publication
29968706 | J:265029
First Author: Kim KY
Year: 2018
Journal: Nat Commun
Title: Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.
Volume: 9
Issue: 1
Pages: 2583
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Publication
31624244 | J:282235
First Author: Dong J
Year: 2019
Journal: Nat Commun
Title: UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells.
Volume: 10
Issue: 1
Pages: 4705
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Publication
24777532 | J:259589
First Author: Obata Y
Year: 2014
Journal: Nat Immunol
Title: The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.
Volume: 15
Issue: 6
Pages: 571-9
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Publication
23463006 | J:205751
 
First Author: Liu X
Year: 2013
Journal: Nat Commun
Title: UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.
Volume: 4
Pages: 1563
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Publication
35472067 | J:325060
 
First Author: Saeki N
Year: 2022
Journal: J Clin Invest
Title: Epigenetic regulator UHRF1 orchestrates proinflammatory gene expression in rheumatoid arthritis in a suppressive manner.
Volume: 132
Issue: 11
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Publication
28976982 | J:246901
First Author: Maenohara S
Year: 2017
Journal: PLoS Genet
Title: Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.
Volume: 13
Issue: 10
Pages: e1007042
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Publication
31515281 | J:285232
First Author: Sun X
Year: 2019
Journal: J Exp Med
Title: TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity.
Volume: 216
Issue: 12
Pages: 2819-2837
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Publication
35284939 | J:335377
First Author: Xiong M
Year: 2022
Journal: Biol Reprod
Title: UHRF1 is indispensable for meiotic sex chromosome inactivation and interacts with the DNA damage response pathway in mice†.
Volume: 107
Issue: 1
Pages: 168-182
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Publication
33634103 | J:305400
 
First Author: Wu Y
Year: 2020
Journal: Front Cell Dev Biol
Title: Maternal UHRF1 Is Essential for Transcription Landscapes and Repression of Repetitive Elements During the Maternal-to-Zygotic Transition.
Volume: 8
Pages: 610773
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Publication
30995416 | J:291201
First Author: Cao Y
Year: 2019
Journal: FASEB J
Title: Deletion of maternal UHRF1 severely reduces mouse oocyte quality and causes developmental defects in preimplantation embryos.
Volume: 33
Issue: 7
Pages: 8294-8305
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Publication
27798843 | J:236865
First Author: Ramesh V
Year: 2016
Journal: Genes Dev
Title: Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration.
Volume: 30
Issue: 19
Pages: 2199-2212
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Publication
27956603 | J:239066
First Author: Zhao J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes.
Volume: 114
Issue: 2
Pages: E142-E151
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Publication
24368767 | J:213030
First Author: Bashtrykov P
Year: 2014
Journal: J Biol Chem
Title: The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.
Volume: 289
Issue: 7
Pages: 4106-15
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Publication
38060382 | J:344223
First Author: Zhang W
Year: 2023
Journal: Cell Rep
Title: NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.
Volume: 42
Issue: 12
Pages: 113531
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Publication
17994007 | J:129097
First Author: Sharif J
Year: 2007
Journal: Nature
Title: The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA.
Volume: 450
Issue: 7171
Pages: 908-12
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Gene
419900 | UHRF1BP1
Type: gene
Organism: chicken
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Publication
9880673 | J:52005
First Author: Fujimori A
Year: 1998
Journal: Mamm Genome
Title: Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation.
Volume: 9
Issue: 12
Pages: 1032-5
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Publication
10984098 | J:342936
First Author: Uemura T
Year: 2000
Journal: Cell Struct Funct
Title: Temporal and spatial localization of novel nuclear protein NP95 in mitotic and meiotic cells.
Volume: 25
Issue: 3
Pages: 149-59
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Publication
28604677 | J:243489
First Author: Graf U
Year: 2017
Journal: Nat Cell Biol
Title: Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.
Volume: 19
Issue: 7
Pages: 763-773
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Publication
14993289 | J:89061
First Author: Citterio E
Year: 2004
Journal: Mol Cell Biol
Title: Np95 is a histone-binding protein endowed with ubiquitin ligase activity.
Volume: 24
Issue: 6
Pages: 2526-35
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Publication
19798101 | J:161259
First Author: Meilinger D
Year: 2009
Journal: EMBO Rep
Title: Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.
Volume: 10
Issue: 11
Pages: 1259-64
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Gene
417929 | UHRF1BP1L
Type: gene
Organism: chicken
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Gene
100428795 | LOC100428795
Type: gene
Organism: macaque, rhesus
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Publication
14741369 | J:87559
First Author: Mori T
Year: 2004
Journal: FEBS Lett
Title: NIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear protein.
Volume: 557
Issue: 1-3
Pages: 209-14
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Publication
32081844 | J:290571
First Author: Pan H
Year: 2020
Journal: Cell Death Dis
Title: UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I.
Volume: 11
Issue: 2
Pages: 142
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Publication
32897881 | J:338188
First Author: Helmin KA
Year: 2020
Journal: J Clin Invest
Title: Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function.
Volume: 130
Issue: 12
Pages: 6571-6587
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Publication
29859850 | J:268867
     
First Author: Murao N
Year: 2018
Journal: Neurosci Res
Title: Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain.
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Publication
25900245 | J:222564
First Author: Qi S
Year: 2015
Journal: J Biol Chem
Title: Non-germ Line Restoration of Genomic Imprinting for a Small Subset of Imprinted Genes in Ubiquitin-like PHD and RING Finger Domain-Containing 1 (Uhrf1) Null Mouse Embryonic Stem Cells.
Volume: 290
Issue: 22
Pages: 14181-91
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Publication
31611260 | J:282188
First Author: Qi S
Year: 2019
Journal: J Immunol
Title: Uhrf1-Mediated Tnf-α Gene Methylation Controls Proinflammatory Macrophages in Experimental Colitis Resembling Inflammatory Bowel Disease.
Volume: 203
Issue: 11
Pages: 3045-3053
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Publication
32609811 | J:294602
First Author: Tauber M
Year: 2020
Journal: Nucleic Acids Res
Title: Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Volume: 48
Issue: 14
Pages: 7728-7747
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UniProt Feature
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase UHRF1
Type: chain
End: 782
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Publication
33616624 | J:304423
 
First Author: Gao ZJ
Year: 2021
Journal: J Exp Med
Title: Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity.
Volume: 218
Issue: 3
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Publication
23754744 | J:204567
First Author: Shamma A
Year: 2013
Journal: Mol Cell Biol
Title: ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.
Volume: 33
Issue: 16
Pages: 3113-24
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Publication
24013172 | J:206103
First Author: Nishiyama A
Year: 2013
Journal: Nature
Title: Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.
Volume: 502
Issue: 7470
Pages: 249-53
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Publication
30487604 | J:267680
First Author: Li Y
Year: 2018
Journal: Nature
Title: Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1.
Volume: 564
Issue: 7734
Pages: 136-140
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Publication
37493331 | J:341543
First Author: Meng TG
Year: 2023
Journal: Adv Sci (Weinh)
Title: NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition.
Volume: 10
Issue: 27
Pages: e2301940
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Protein Coding Gene
MGP_CAROLIEiJ_G0021775 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023882 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023883 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1338889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024329 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023129 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023751 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023745 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020764 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022686 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
17182844 | J:124025
First Author: Papait R
Year: 2007
Journal: Mol Biol Cell
Title: Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing.
Volume: 18
Issue: 3
Pages: 1098-106
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816989
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816989
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816989
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816989
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816989
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816989
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816989
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3816185
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816989
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:4948755
Assay Type: RT-PCR
Annotation Date: 2011-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618213
Stage: TS13
Assay Id: MGI:4948880
Age: embryonic day 8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4948755
Assay Type: RT-PCR
Annotation Date: 2011-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666821
Stage: TS21
Assay Id: MGI:4948880
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4948755
Assay Type: RT-PCR
Annotation Date: 2011-05-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842828
Stage: TS28
Assay Id: MGI:4948880
Age: postnatal day 90
Specimen Label: P90
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7428781
Assay Type: RT-PCR
Annotation Date: 2023-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7428795
Age: embryonic day 9.5
Image: S10
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7428781
Assay Type: RT-PCR
Annotation Date: 2023-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7428795
Age: embryonic day 9.5
Image: S10
Specimen Label: Ehmt2-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7432694
Assay Type: RT-PCR
Annotation Date: 2023-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7432730
Age: embryonic day 9.5
Image: 2
Specimen Label: Em
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7432694
Assay Type: RT-PCR
Annotation Date: 2023-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604615
Stage: TS15
Assay Id: MGI:7432730
Age: embryonic day 9.5
Image: 2
Specimen Label: Tr
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4844706
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4848576
Age: embryonic day 9.5
Note: Staining is present in the mandibular arch.
Specimen Label: Table S4 - E9.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4844706
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848576
Age: embryonic day 10.5
Note: Staining is present in the mandibular arch.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4844706
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1611819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4848576
Age: embryonic day 11.5
Note: Staining is present in the mandibular arch.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310488
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5423811
Age: embryonic day 14.5
Specimen Label: EN97; Specimen N186
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5310488
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5423811
Age: embryonic day 14.5
Specimen Label: EN97; Specimen N186
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3506801
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3508245
Age: embryonic day 13.5
Image: 1
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
•
•
•
•
•




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