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Search results 1 to 100 out of 405 for Ulk1

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Hits by Pathway

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Type Details Score
Gene
8408 | ULK1
Type: gene
Organism: human
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Gene
526310 | ULK1
Type: gene
Organism: cattle
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Gene
416800 | ULK1
Type: gene
Organism: chicken
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Gene
709746 | ULK1
Type: gene
Organism: macaque, rhesus
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Gene
100127200 | ulk1
Type: gene
Organism: frog, western clawed
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Gene
360827 | Ulk1
Type: gene
Organism: rat
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Gene
477437 | ULK1
Type: gene
Organism: dog, domestic
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Gene
744289 | ULK1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1270126 | Ulk1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21205641 | J:167980
First Author: Egan DF
Year: 2011
Journal: Science
Title: Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Volume: 331
Issue: 6016
Pages: 456-61
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Publication
30021155 | J:288994
First Author: Shibata S
Year: 2018
Journal: Cell Rep
Title: ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor.
Volume: 24
Issue: 3
Pages: 569-576
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Publication
9600096 | J:47612
First Author: Yan J
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51.
Volume: 246
Issue: 1
Pages: 222-7
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Publication
21795849 | J:314079
First Author: Jung CH
Year: 2011
Journal: Autophagy
Title: ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.
Volume: 7
Issue: 10
Pages: 1212-21
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Publication
24671035 | J:219042
First Author: Wu W
Year: 2014
Journal: EMBO Rep
Title: ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy.
Volume: 15
Issue: 5
Pages: 566-75
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Publication
25980607 | J:227363
First Author: Tian W
Year: 2015
Journal: FEBS Lett
Title: Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy.
Volume: 589
Issue: 15
Pages: 1847-54
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Publication
28011640 | J:240711
First Author: Goldberg AA
Year: 2017
Journal: J Biol Chem
Title: Regulation of ULK1 Expression and Autophagy by STAT1.
Volume: 292
Issue: 5
Pages: 1899-1909
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Publication
23685627 | J:198998
First Author: Russell RC
Year: 2013
Journal: Nat Cell Biol
Title: ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.
Volume: 15
Issue: 7
Pages: 741-50
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Publication
32868073 | J:305113
First Author: Sutula GI
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Inducible Ulk1 expression activates the p53 protein in mouse embryonic stem cells.
Volume: 532
Issue: 2
Pages: 280-284
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Publication
18539900 | J:139213
First Author: Kundu M
Year: 2008
Journal: Blood
Title: Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation.
Volume: 112
Issue: 4
Pages: 1493-502
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Publication
27617292 | J:236977
First Author: Yang M
Year: 2016
Journal: Sci Adv
Title: A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.
Volume: 2
Issue: 9
Pages: e1601167
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Publication
37306101 | J:342766
First Author: Ikeda R
Year: 2023
Journal: EMBO J
Title: Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
Volume: 42
Issue: 14
Pages: e113349
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Publication
28430962 | J:258861
First Author: An M
Year: 2017
Journal: Cardiovasc Res
Title: ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipid metabolism.
Volume: 113
Issue: 10
Pages: 1137-1147
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Publication
17595159 | J:124765
First Author: Chan EY
Year: 2007
Journal: J Biol Chem
Title: siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.
Volume: 282
Issue: 35
Pages: 25464-74
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Publication
32273498 | J:287094
First Author: Torii S
Year: 2020
Journal: Nat Commun
Title: Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy.
Volume: 11
Issue: 1
Pages: 1754
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Publication
30979586 | J:275687
First Author: Wang B
Year: 2019
Journal: Mol Cell
Title: ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.
Volume: 74
Issue: 4
Pages: 742-757.e8
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Publication
26687681 | J:232813
First Author: Liu CC
Year: 2016
Journal: Mol Cell
Title: Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.
Volume: 61
Issue: 1
Pages: 84-97
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Publication
31123703 | J:289323
First Author: Di Rienzo M
Year: 2019
Journal: Sci Adv
Title: Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains.
Volume: 5
Issue: 5
Pages: eaau8857
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Publication
28916822 | J:252248
First Author: Laker RC
Year: 2017
Journal: Nat Commun
Title: Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy.
Volume: 8
Issue: 1
Pages: 548
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Publication
26138443 | J:258903
First Author: Joshi A
Year: 2016
Journal: Cell Death Differ
Title: Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1.
Volume: 23
Issue: 2
Pages: 216-30
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Publication
25723488 | J:343213
First Author: Lim J
Year: 2015
Journal: PLoS Genet
Title: Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates.
Volume: 11
Issue: 2
Pages: e1004987
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Publication
35104184 | J:333248
First Author: Harris MP
Year: 2022
Journal: Autophagy
Title: Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function.
Volume: 18
Issue: 9
Pages: 2161-2177
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Publication
31434755 | J:278703
 
First Author: Lechauve C
Year: 2019
Journal: Sci Transl Med
Title: The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia.
Volume: 11
Issue: 506
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Publication
25040165 | J:213953
First Author: Ro SH
Year: 2014
Journal: FEBS J
Title: Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1.
Volume: 281
Issue: 17
Pages: 3816-27
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Publication
29099309 | J:302618
First Author: Wang B
Year: 2018
Journal: Autophagy
Title: The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.
Volume: 14
Issue: 5
Pages: 796-811
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Publication
10624947 | J:59129
First Author: Tomoda T
Year: 1999
Journal: Neuron
Title: A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons.
Volume: 24
Issue: 4
Pages: 833-46
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Publication
19258318 | J:149848
First Author: Ganley IG
Year: 2009
Journal: J Biol Chem
Title: ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.
Volume: 284
Issue: 18
Pages: 12297-305
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Publication
22539723 | J:183987
First Author: Lin SY
Year: 2012
Journal: Science
Title: GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy.
Volume: 336
Issue: 6080
Pages: 477-81
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Publication
21258367 | J:175316
First Author: Kim J
Year: 2011
Journal: Nat Cell Biol
Title: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Volume: 13
Issue: 2
Pages: 132-41
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Publication
19225151 | J:314078
First Author: Jung CH
Year: 2009
Journal: Mol Biol Cell
Title: ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.
Volume: 20
Issue: 7
Pages: 1992-2003
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Publication
18936157 | J:314077
First Author: Chan EY
Year: 2009
Journal: Mol Cell Biol
Title: Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.
Volume: 29
Issue: 1
Pages: 157-71
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Publication
22613832 | J:185211
First Author: Longatti A
Year: 2012
Journal: J Cell Biol
Title: TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes.
Volume: 197
Issue: 5
Pages: 659-75
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Publication
27153534 | J:249058
First Author: Li TY
Year: 2016
Journal: Mol Cell
Title: ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.
Volume: 62
Issue: 3
Pages: 359-370
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Publication
28356270 | J:243307
First Author: Call JA
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle.
Volume: 312
Issue: 6
Pages: C724-C732
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Publication
29680658 | J:273423
First Author: Wei HL
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deficiency of unc-51 like kinase 1 (Ulk1) protects against mice traumatic brain injury (TBI) by suppression of p38 and JNK pathway.
Volume: 503
Issue: 2
Pages: 467-473
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Publication
24317201 | J:229149
First Author: Jang YH
Year: 2014
Journal: Cell Death Differ
Title: Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy.
Volume: 21
Issue: 4
Pages: 533-46
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Publication
26310906 | J:224974
 
First Author: Wong PM
Year: 2015
Journal: Nat Commun
Title: Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A.
Volume: 6
Pages: 8048
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Publication
31721614 | J:283527
First Author: Nichenko AS
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice.
Volume: 318
Issue: 2
Pages: C242-C252
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Publication
33669246 | J:308447
 
First Author: Nichenko AS
Year: 2021
Journal: Int J Mol Sci
Title: Lifelong Ulk1-Mediated Autophagy Deficiency in Muscle Induces Mitochondrial Dysfunction and Contractile Weakness.
Volume: 22
Issue: 4
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Publication
15014045 | J:89027
First Author: Tomoda T
Year: 2004
Journal: Genes Dev
Title: Role of Unc51.1 and its binding partners in CNS axon outgrowth.
Volume: 18
Issue: 5
Pages: 541-58
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Publication
19211835 | J:153377
First Author: Hosokawa N
Year: 2009
Journal: Mol Biol Cell
Title: Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
Volume: 20
Issue: 7
Pages: 1981-91
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Publication
27203176 | J:248719
First Author: Joo JH
Year: 2016
Journal: Mol Cell
Title: The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.
Volume: 62
Issue: 4
Pages: 491-506
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Publication
22452982 | J:321074
First Author: Jacquel A
Year: 2012
Journal: Blood
Title: Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.
Volume: 119
Issue: 19
Pages: 4527-31
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Publication
34658916 | J:312668
 
First Author: Drake JC
Year: 2021
Journal: Front Physiol
Title: Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle.
Volume: 12
Pages: 732308
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Publication
21460635 | J:246385
First Author: Lee EJ
Year: 2011
Journal: Autophagy
Title: The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy.
Volume: 7
Issue: 7
Pages: 689-95
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Publication
18443221 | J:136659
First Author: Hara T
Year: 2008
Journal: J Cell Biol
Title: FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
Volume: 181
Issue: 3
Pages: 497-510
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Publication
21855797 | J:215871
First Author: Joo JH
Year: 2011
Journal: Mol Cell
Title: Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.
Volume: 43
Issue: 4
Pages: 572-85
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Publication
25686248 | J:245269
First Author: Rui YN
Year: 2015
Journal: Nat Cell Biol
Title: Huntingtin functions as a scaffold for selective macroautophagy.
Volume: 17
Issue: 3
Pages: 262-75
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Publication
28381396 | J:242017
First Author: Man N
Year: 2017
Journal: Blood
Title: Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner.
Volume: 129
Issue: 20
Pages: 2782-2792
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Publication
30581007 | J:290246
First Author: Zhang A
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Unc-51 like autophagy activating kinase 1 accelerates angiotensin II-induced cardiac hypertrophy through promoting oxidative stress regulated by Nrf-2/HO-1 pathway.
Volume: 509
Issue: 1
Pages: 32-39
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Publication
32804155 | J:299987
First Author: Ma Z
Year: 2020
Journal: J Clin Invest
Title: p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease.
Volume: 130
Issue: 9
Pages: 5011-5026
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Publication
17389358 | J:120306
First Author: Zhou X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons.
Volume: 104
Issue: 14
Pages: 5842-7
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Publication
30053525 | J:265690
 
First Author: Li RL
Year: 2018
Journal: J Mol Cell Cardiol
Title: Irisin alleviates pressure overload-induced cardiac hypertrophy by inducing protective autophagy via mTOR-independent activation of the AMPK-ULK1 pathway.
Volume: 121
Pages: 242-255
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Publication
21220506 | J:167845
First Author: Itakura E
Year: 2011
Journal: J Cell Biol
Title: p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.
Volume: 192
Issue: 1
Pages: 17-27
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Publication
36608143 | J:345168
First Author: Kremer LS
Year: 2023
Journal: PLoS Genet
Title: A role for BCL2L13 and autophagy in germline purifying selection of mtDNA.
Volume: 19
Issue: 1
Pages: e1010573
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Publication
21690395 | J:174297
First Author: Cheong H
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ammonia-induced autophagy is independent of ULK1/ULK2 kinases.
Volume: 108
Issue: 27
Pages: 11121-6
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Publication
32980459 | J:305665
First Author: Jiang YJ
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Excessive ROS production and enhanced autophagy contribute to myocardial injury induced by branched-chain amino acids: Roles for the AMPK-ULK1 signaling pathway and α7nAChR.
Volume: 1867
Issue: 1
Pages: 165980
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Publication
25541949 | J:225384
First Author: Xing J
Year: 2014
Journal: PLoS One
Title: Upregulation of Unc-51-like kinase 1 by nitric oxide stabilizes SIRT1, independent of autophagy.
Volume: 9
Issue: 12
Pages: e116165
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Publication
24275123 | J:302676
First Author: Cheong H
Year: 2014
Journal: Autophagy
Title: Analysis of a lung defect in autophagy-deficient mouse strains.
Volume: 10
Issue: 1
Pages: 45-56
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Publication
31059511 | J:275030
First Author: Ferder IC
Year: 2019
Journal: PLoS Genet
Title: Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.
Volume: 15
Issue: 5
Pages: e1008084
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Protein Coding Gene
MGP_CAROLIEiJ_G0027552 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029893 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1270126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029664 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024134 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028550 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
31361392 | J:329343
First Author: Wang L
Year: 2020
Journal: FEBS J
Title: mTORC1-PGC1 axis regulates mitochondrial remodeling during reprogramming.
Volume: 287
Issue: 1
Pages: 108-121
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GXD Expression
GXD Expression
     
Probe: MGI:7567810
Assay Type: Western blot
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:7567827
Age: embryonic day 17.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7567810
Assay Type: Western blot
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:7567827
Age: embryonic day 17.5
Specimen Label: Efhd1 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7567811
Assay Type: Western blot
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:7567828
Age: embryonic day 17.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7567811
Assay Type: Western blot
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:7567828
Age: embryonic day 17.5
Specimen Label: Efhd1 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7616384
Age: postnatal day 0
Specimen Label: IP +/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7616384
Age: postnatal day 0
Specimen Label: IP f/f
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7616384
Age: postnatal day 0
Specimen Label: IP f/f;cre+
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7616384
Age: postnatal day 0
Specimen Label: Lysate +/+
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7616384
Age: postnatal day 0
Specimen Label: Lysate f/f
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7616384
Age: postnatal day 0
Specimen Label: Lysate f/f;cre/+
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7616362
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7616418
Age: embryonic day 18.5
Specimen Label: control
Detected: true
Specimen Num: 1
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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