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Search results 1 to 100 out of 102 for Unc13d

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Hits by Category

Type Details Score
Gene
201294 | UNC13D
Type: gene
Organism: human
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Gene
454891 | UNC13D
Type: gene
Organism: chimpanzee
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Gene
506146 | UNC13D
Type: gene
Organism: cattle
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Gene
417369 | UNC13D
Type: gene
Organism: chicken
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Gene
564076 | unc13d
Type: gene
Organism: zebrafish
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Gene
704431 | UNC13D
Type: gene
Organism: macaque, rhesus
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Gene
100145635 | unc13d
Type: gene
Organism: frog, western clawed
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Gene
192177 | Unc13d
Type: gene
Organism: rat
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Gene
483319 | UNC13D
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1917700 | Unc13d
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30892133 | J:319593
First Author: Zhang J
Year: 2019
Journal: Autophagy
Title: Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency.
Volume: 15
Issue: 10
Pages: 1738-1756
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Publication
37595758 | J:340773
     
First Author: Dettmer-Monaco V
Year: 2023
Journal: J Allergy Clin Immunol
Title: Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis.
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Protein Coding Gene
MGP_CAROLIEiJ_G0017428 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019381 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019355 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1917700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019805 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018716 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019244 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019236 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019314 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019269 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018768 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018557 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018273 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
23659589 | J:231217
First Author: Stegner D
Year: 2013
Journal: J Thromb Haemost
Title: Munc13-4-mediated secretion is essential for infarct progression but not intracranial hemostasis in acute stroke.
Volume: 11
Issue: 7
Pages: 1430-3
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Publication
25158625 | J:230479
First Author: Jonnalagadda D
Year: 2014
Journal: Biochim Biophys Acta
Title: Granule-mediated release of sphingosine-1-phosphate by activated platelets.
Volume: 1841
Issue: 11
Pages: 1581-9
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Publication
24488096 | J:229350
First Author: Bird CH
Year: 2014
Journal: Cell Death Differ
Title: The granzyme B-Serpinb9 axis controls the fate of lymphocytes after lysosomal stress.
Volume: 21
Issue: 6
Pages: 876-87
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Publication
20435885 | J:163507
First Author: Ren Q
Year: 2010
Journal: Blood
Title: Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis.
Volume: 116
Issue: 6
Pages: 869-77
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Publication
29884704 | J:264055
First Author: Bin NR
Year: 2018
Journal: J Immunol
Title: C2 Domains of Munc13-4 Are Crucial for Ca2+-Dependent Degranulation and Cytotoxicity in NK Cells.
Volume: 201
Issue: 2
Pages: 700-713
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Publication
25239803 | J:218680
First Author: Yang F
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Granule cargo release from bone marrow-derived cells sustains cardiac hypertrophy.
Volume: 307
Issue: 10
Pages: H1529-38
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Publication
26637270 | J:239507
First Author: Chicka MC
Year: 2016
Journal: Biochem J
Title: Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion.
Volume: 473
Issue: 5
Pages: 627-39
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Publication
21746860 | J:175690
First Author: Johnson JL
Year: 2011
Journal: Infect Immun
Title: Increased survival and reduced neutrophil infiltration of the liver in Rab27a- but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation.
Volume: 79
Issue: 9
Pages: 3607-18
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Publication
28077416 | J:240698
First Author: Deppermann C
Year: 2017
Journal: Blood
Title: Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice.
Volume: 129
Issue: 12
Pages: 1702-1706
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Publication
31171812 | J:281224
First Author: Kiran Gotru S
Year: 2019
Journal: Sci Rep
Title: Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases.
Volume: 9
Issue: 1
Pages: 8333
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Publication
23810565 | J:199146
First Author: Schumacher D
Year: 2013
Journal: Cancer Cell
Title: Platelet-derived nucleotides promote tumor-cell transendothelial migration and metastasis via P2Y2 receptor.
Volume: 24
Issue: 1
Pages: 130-7
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Publication
17420270 | J:119974
First Author: Crozat K
Year: 2007
Journal: J Exp Med
Title: Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis.
Volume: 204
Issue: 4
Pages: 853-63
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Publication
29519941 | J:285152
First Author: Adam F
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability.
Volume: 38
Issue: 5
Pages: 1037-1051
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Publication
26800051 | J:252442
First Author: Wolf K
Year: 2016
Journal: PLoS One
Title: Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.
Volume: 11
Issue: 1
Pages: e0147664
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Publication
36278424 | J:331987
First Author: Weißert K
Year: 2022
Journal: EMBO Mol Med
Title: Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH).
Volume: 14
Issue: 12
Pages: e16085
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Publication
23590328 | J:341931
First Author: Dudenhöffer-Pfeifer M
Year: 2013
Journal: Traffic
Title: Different Munc13 isoforms function as priming factors in lytic granule release from murine cytotoxic T lymphocytes.
Volume: 14
Issue: 7
Pages: 798-809
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Publication
21239699 | J:170516
First Author: Crozat K
Year: 2011
Journal: Blood
Title: Impact of β2 integrin deficiency on mouse natural killer cell development and function.
Volume: 117
Issue: 10
Pages: 2874-82
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Publication
29141910 | J:256061
First Author: Rodarte EM
Year: 2018
Journal: J Biol Chem
Title: Munc13 proteins control regulated exocytosis in mast cells.
Volume: 293
Issue: 1
Pages: 345-358
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Publication
18354201 | J:133380
First Author: Higashio H
Year: 2008
Journal: J Immunol
Title: Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells.
Volume: 180
Issue: 7
Pages: 4774-84
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Publication
23115246 | J:193760
First Author: Monfregola J
Year: 2012
Journal: J Biol Chem
Title: MUNC13-4 protein regulates the oxidative response and is essential for phagosomal maturation and bacterial killing in neutrophils.
Volume: 287
Issue: 53
Pages: 44603-18
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Publication
27079884 | J:247079
First Author: Crescente M
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.
Volume: 36
Issue: 6
Pages: 1164-73
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Publication
25526309 | J:302262
First Author: Prakash MD
Year: 2014
Journal: Immunity
Title: Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.
Volume: 41
Issue: 6
Pages: 960-72
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Publication
33176450 | J:318571
First Author: Xiang B
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Calcium Ion Chelation Preserves Platelet Function During Cold Storage.
Volume: 41
Issue: 1
Pages: 234-249
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Publication
21606480 | J:174873
First Author: Lykens JE
Year: 2011
Journal: Blood
Title: Perforin is a critical physiologic regulator of T-cell activation.
Volume: 118
Issue: 3
Pages: 618-26
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Publication
16688530 | J:105543
First Author: Crozat K
Year: 2006
Journal: Mamm Genome
Title: Analysis of the MCMV resistome by ENU mutagenesis.
Volume: 17
Issue: 5
Pages: 398-406
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Publication
32040544 | J:289659
First Author: Mammadova-Bach E
Year: 2020
Journal: Blood
Title: Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived galectin-3.
Volume: 135
Issue: 14
Pages: 1146-1160
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Publication
23281710 | J:211540
First Author: Singh RK
Year: 2013
Journal: FEBS J
Title: Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion.
Volume: 280
Issue: 3
Pages: 892-903
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Publication
26575293 | J:238441
   
First Author: Man KN
Year: 2015
Journal: Elife
Title: Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.
Volume: 4
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Publication
22589474 | J:189036
First Author: Peters CG
Year: 2012
Journal: Blood
Title: Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7.
Volume: 120
Issue: 1
Pages: 199-206
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Publication
26916731 | J:246464
First Author: Pachel C
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of Platelet GPVI Protects Against Myocardial Ischemia-Reperfusion Injury.
Volume: 36
Issue: 4
Pages: 629-35
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Publication
21551232 | J:174800
First Author: Krebs P
Year: 2011
Journal: Blood
Title: Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice.
Volume: 117
Issue: 24
Pages: 6582-8
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Publication
25609709 | J:223843
First Author: Vogl C
Year: 2015
Journal: J Cell Sci
Title: Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.
Volume: 128
Issue: 4
Pages: 638-44
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Publication
15020428 | J:88776
First Author: Du X
Year: 2004
Journal: Genetics
Title: Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice.
Volume: 166
Issue: 1
Pages: 331-40
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Publication
32929010 | J:296273
First Author: Gupta S
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation.
Volume: 117
Issue: 39
Pages: 24316-24325
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Publication
27701149 | J:239621
First Author: Kurz AR
Year: 2016
Journal: J Clin Invest
Title: MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane.
Volume: 126
Issue: 11
Pages: 4125-4139
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Publication
25908104 | J:224632
First Author: Lowe KL
Year: 2015
Journal: Blood
Title: Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development.
Volume: 125
Issue: 24
Pages: 3769-77
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Publication
26720279 | J:310568
First Author: Parikh BA
Year: 2015
Journal: PLoS Pathog
Title: Dual Requirement of Cytokine and Activation Receptor Triggering for Cytotoxic Control of Murine Cytomegalovirus by NK Cells.
Volume: 11
Issue: 12
Pages: e1005323
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q80UG7
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: false
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Allele
Unc13d<Jinx> | MGI:3628822
 
Name: unc-13 homolog D; Jinx
Allele Type: Chemically induced (ENU)
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Genotype
Genotype
Symbol: Unc13d/Unc13d
Background: C57BL/6J-Unc13d/Mmucd
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110923 | familial hemophagocytic lymphohistiocytosis 3
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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