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Search results 1 to 100 out of 505 for Ung

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0.064s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Xue JH
Year: 2016
Journal: J Biol Chem
Title: Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation.
Volume: 291
Issue: 2
Pages: 731-8
Publication
First Author: Cortizas EM
Year: 2016
Journal: J Exp Med
Title: UNG protects B cells from AID-induced telomere loss.
Volume: 213
Issue: 11
Pages: 2459-2472
Publication
First Author: Nilsen H
Year: 2003
Journal: Oncogene
Title: Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.
Volume: 22
Issue: 35
Pages: 5381-6
Publication
First Author: Pérez-Durán P
Year: 2012
Journal: J Exp Med
Title: UNG shapes the specificity of AID-induced somatic hypermutation.
Volume: 209
Issue: 7
Pages: 1379-89
Publication
First Author: Ung DC
Year: 2018
Journal: Mol Psychiatry
Title: Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.
Volume: 23
Issue: 5
Pages: 1356-1367
Publication  
First Author: Krokan HE
Year: 2001
Journal: Prog Nucleic Acid Res Mol Biol
Title: Properties and functions of human uracil-DNA glycosylase from the UNG gene.
Volume: 68
Pages: 365-86
Publication
First Author: Zan H
Year: 2012
Journal: Cell Rep
Title: Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination.
Volume: 2
Issue: 5
Pages: 1220-32
Publication
First Author: Delgado P
Year: 2020
Journal: PLoS Genet
Title: Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma.
Volume: 16
Issue: 12
Pages: e1008960
Publication
First Author: Frieder D
Year: 2009
Journal: Mol Cell Biol
Title: The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs.
Volume: 29
Issue: 18
Pages: 5148-57
Publication
First Author: Svendsen PC
Year: 1997
Journal: Gene
Title: The mouse uracil-DNA glycosylase gene: isolation of cDNA and genomic clones and mapping ung to mouse chromosome 5.
Volume: 189
Issue: 2
Pages: 175-81
Publication
First Author: Ranjit S
Year: 2011
Journal: J Immunol
Title: AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Volume: 187
Issue: 5
Pages: 2464-75
Publication
First Author: Nilsen H
Year: 1997
Journal: Nucleic Acids Res
Title: Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene.
Volume: 25
Issue: 4
Pages: 750-5
Publication
First Author: An Q
Year: 2005
Journal: EMBO J
Title: C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases.
Volume: 24
Issue: 12
Pages: 2205-13
Publication
First Author: Li S
Year: 2013
Journal: Mol Immunol
Title: Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
Volume: 53
Issue: 3
Pages: 214-7
Publication
First Author: Alsøe L
Year: 2017
Journal: Sci Rep
Title: Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
Volume: 7
Issue: 1
Pages: 7199
Publication
First Author: Zanotti KJ
Year: 2019
Journal: J Immunol
Title: DNA Breaks in Ig V Regions Are Predominantly Single Stranded and Are Generated by UNG and MSH6 DNA Repair Pathways.
Volume: 202
Issue: 5
Pages: 1573-1581
Publication
First Author: Nilsen H
Year: 2000
Journal: Nucleic Acids Res
Title: Analysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues.
Volume: 28
Issue: 12
Pages: 2277-85
Publication
First Author: Nilsen H
Year: 2005
Journal: Oncogene
Title: Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice.
Volume: 24
Issue: 18
Pages: 3063-6
Publication
First Author: Nilsen H
Year: 2000
Journal: Mol Cell
Title: Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication.
Volume: 5
Issue: 6
Pages: 1059-65
Publication
First Author: Yousif AS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase.
Volume: 111
Issue: 11
Pages: E1016-24
Publication
First Author: Linhart HG
Year: 2009
Journal: Gastroenterology
Title: Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.
Volume: 136
Issue: 1
Pages: 227-235.e3
Publication
First Author: Kronenberg G
Year: 2008
Journal: J Neurosci
Title: Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
Volume: 28
Issue: 28
Pages: 7219-30
Publication
First Author: Andersen S
Year: 2005
Journal: DNA Repair (Amst)
Title: Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
Volume: 4
Issue: 12
Pages: 1432-41
Publication
First Author: Longerich S
Year: 2005
Journal: J Exp Med
Title: The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
Volume: 202
Issue: 10
Pages: 1443-54
Publication
First Author: Rada C
Year: 2002
Journal: Curr Biol
Title: Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice.
Volume: 12
Issue: 20
Pages: 1748-55
Publication
First Author: Di Noia JM
Year: 2007
Journal: J Exp Med
Title: Dependence of antibody gene diversification on uracil excision.
Volume: 204
Issue: 13
Pages: 3209-19
Publication
First Author: Rada C
Year: 2004
Journal: Mol Cell
Title: Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation.
Volume: 16
Issue: 2
Pages: 163-71
Publication
First Author: Endres M
Year: 2004
Journal: J Clin Invest
Title: Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.
Volume: 113
Issue: 12
Pages: 1711-21
Publication
First Author: Begum NA
Year: 2007
Journal: J Biol Chem
Title: Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.
Volume: 282
Issue: 1
Pages: 731-42
Publication
First Author: Zahn A
Year: 2013
Journal: J Immunol
Title: Separation of function between isotype switching and affinity maturation in vivo during acute immune responses and circulating autoantibodies in UNG-deficient mice.
Volume: 190
Issue: 12
Pages: 5949-60
Publication
First Author: Doseth B
Year: 2011
Journal: J Biol Chem
Title: Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse.
Volume: 286
Issue: 19
Pages: 16669-80
Publication
First Author: Zan H
Year: 2008
Journal: Mol Immunol
Title: AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID.
Volume: 46
Issue: 1
Pages: 45-61
Publication
First Author: Stavnezer J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.
Volume: 111
Issue: 25
Pages: 9217-22
Publication
First Author: Zivojnovic M
Year: 2014
Journal: Mol Cell Biol
Title: Somatic hypermutation at A/T-rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds.
Volume: 34
Issue: 12
Pages: 2176-87
Publication
First Author: Di Noia JM
Year: 2006
Journal: EMBO J
Title: SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair.
Volume: 25
Issue: 3
Pages: 585-95
Publication
First Author: Gu X
Year: 2016
Journal: Blood
Title: AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma.
Volume: 127
Issue: 1
Pages: 102-12
Publication
First Author: Kemmerich K
Year: 2012
Journal: Nucleic Acids Res
Title: Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
Volume: 40
Issue: 13
Pages: 6016-25
Publication
First Author: Choi JE
Year: 2020
Journal: J Immunol
Title: AID Phosphorylation Regulates Mismatch Repair-Dependent Class Switch Recombination and Affinity Maturation.
Volume: 204
Issue: 1
Pages: 13-22
Publication
First Author: Girelli Zubani G
Year: 2017
Journal: J Exp Med
Title: Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.
Volume: 214
Issue: 4
Pages: 1169-1180
Publication
First Author: Shen HM
Year: 2006
Journal: J Immunol
Title: Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice.
Volume: 177
Issue: 8
Pages: 5386-92
Publication
First Author: Xue K
Year: 2006
Journal: J Exp Med
Title: The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice.
Volume: 203
Issue: 9
Pages: 2085-94
Publication
First Author: Pettersen HS
Year: 2011
Journal: Nucleic Acids Res
Title: UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Volume: 39
Issue: 19
Pages: 8430-44
Publication
First Author: Schrader CE
Year: 2007
Journal: J Immunol
Title: Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair.
Volume: 179
Issue: 9
Pages: 6064-71
Protein
Organism: Mus musculus
Length: 199  
Fragment?: false
Protein
Organism: Mus musculus
Length: 295  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Li YY
Year: 2001
Journal: Circulation
Title: Mitochondrial abnormalities in tumor necrosis factor-alpha-induced heart failure are associated with impaired DNA repair activity.
Volume: 104
Issue: 20
Pages: 2492-7
Publication
First Author: Lauritzen KH
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure.
Volume: 309
Issue: 3
Pages: H434-49
Publication
First Author: Endres M
Year: 2005
Journal: Stroke
Title: Folate deficiency increases postischemic brain injury.
Volume: 36
Issue: 2
Pages: 321-5
Publication
First Author: Kronenberg G
Year: 2011
Journal: Exp Neurol
Title: Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase.
Volume: 228
Issue: 2
Pages: 253-8
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1860616
Age: embryonic day 17.0
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1860616
Age: embryonic day 15.0
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1860616
Age: embryonic day 11.0
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1860616
Age: embryonic day 7.0
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1860625
Age: embryonic day 17.0
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1860625
Age: embryonic day 15.0
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1860625
Age: embryonic day 11.0
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1860625
Age: embryonic day 7.0
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1860519
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1860616
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression        
Probe: MGI:1860520
Assay Type: Northern blot
Annotation Date: 2000-07-24
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1860625
Age: postnatal adult
Specimen Num: 7
GXD Expression    
Probe: MGI:5829722
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Moderate
Sex: Male
Emaps: EMAPS:2918122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829761
Age: embryonic day 14.5
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5829722
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Weak
Sex: Female
Emaps: EMAPS:1898725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5829761
Age: embryonic day 17.5
Note: Low expression was detected in the mesenchymal layer.
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5829722
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Female
Emaps: EMAPS:3121925
Stage: TS25
Assay Id: MGI:5829761
Age: embryonic day 17.5
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5829722
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Female
Emaps: EMAPS:2994525
Stage: TS25
Assay Id: MGI:5829761
Age: embryonic day 17.5
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5829722
Assay Type: RNA in situ
Annotation Date: 2017-03-28
Strength: Absent
Sex: Female
Emaps: EMAPS:3611025
Stage: TS25
Assay Id: MGI:5829761
Age: embryonic day 17.5
Detected: false
Specimen Num: 10