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Search results 1 to 100 out of 229 for Upf2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
26019 | UPF2
Type: gene
Organism: human
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Gene
487130 | UPF2
Type: gene
Organism: dog, domestic
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Gene
450304 | UPF2
Type: gene
Organism: chimpanzee
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Gene
781181 | UPF2
Type: gene
Organism: cattle
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Gene
419100 | UPF2
Type: gene
Organism: chicken
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Gene
569006 | upf2
Type: gene
Organism: zebrafish
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Gene
693842 | UPF2
Type: gene
Organism: macaque, rhesus
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Gene
100158573 | upf2
Type: gene
Organism: frog, western clawed
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Gene
361271 | Upf2
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2449307 | Upf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31636381 | J:328957
First Author: Notaras M
Year: 2020
Journal: Mol Psychiatry
Title: UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function.
Volume: 25
Issue: 12
Pages: 3360-3379
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Publication
20657840 | J:163097
First Author: Thoren LA
Year: 2010
Journal: PLoS One
Title: UPF2 is a critical regulator of liver development, function and regeneration.
Volume: 5
Issue: 7
Pages: e11650
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Publication
31585809 | J:282585
First Author: Johnson JL
Year: 2019
Journal: Neuron
Title: Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response.
Volume: 104
Issue: 4
Pages: 665-679.e8
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Publication
25503407 | J:237435
First Author: Bao J
Year: 2015
Journal: Development
Title: UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome.
Volume: 142
Issue: 2
Pages: 352-62
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Publication
18483223 | J:134765
First Author: Weischenfeldt J
Year: 2008
Journal: Genes Dev
Title: NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
Volume: 22
Issue: 10
Pages: 1381-96
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Publication
28444146 | J:247924
First Author: MacDonald CC
Year: 2017
Journal: Biol Reprod
Title: Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction.
Volume: 96
Issue: 5
Pages: 939-947
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Protein Coding Gene
MGP_CAROLIEiJ_G0023157 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025273 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025301 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2449307 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025743 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019217 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024075 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Liver
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Kidney
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Pancreas
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5908564
Assay Type: Western blot
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908578
Age: postnatal adult
Image: S1
Specimen Label: Testis
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Not Specified
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:5908579
Age: embryonic day 12.5
Image: S1
Specimen Label: E12.5
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5908579
Age: embryonic day 15.5
Image: S1
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797226
Stage: TS26
Assay Id: MGI:5908579
Age: embryonic day 18.5
Image: S1
Specimen Label: E18.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:5908579
Age: postnatal day 0
Image: S1
Specimen Label: P0
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 5
Image: S1
Specimen Label: P5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 10
Image: S1
Specimen Label: P10
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 14
Image: S1
Specimen Label: P14
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 17
Image: S1
Specimen Label: P17
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 21
Image: S1
Specimen Label: P21
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 35
Image: S1
Specimen Label: P35
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5908571
Assay Type: RT-PCR
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5908579
Age: postnatal day 60
Image: S1
Specimen Label: P60
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:5908564
Assay Type: Immunohistochemistry
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5908580
Age: postnatal adult
Image: 1B
Note: Abundant expression in cytoplasm of spermatocytes and round spermatids. Highest expression confined to an intensive "dot-like" structure resembling the chromatoid body (CB) in round spermatids.
Specimen Label: 1B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5908564
Assay Type: Immunohistochemistry
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5908580
Age: postnatal adult
Image: 1C
Note: Authors report consistent co-localization with chromatoid body (CB) marker MAEL in most round spermatids.
Specimen Label: 1C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5908564
Assay Type: Immunohistochemistry
Annotation Date: 2017-09-08
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5908580
Age: postnatal adult
Image: 1D
Note: Authors report consistent co-localization with chromatoid body (CB) marker DDX25 in most round spermatids at both stages VIII and I.
Specimen Label: 1D
Detected: true
Specimen Num: 3
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Publication
- | J:81430
   
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, similar to regulator of nonsense transcripts 2, clone IMAGE: 4973397, mRNA
Pages: BC039278
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Publication
36255229 | J:331055
 
First Author: Chousal JN
Year: 2022
Journal: Development
Title: Progression of the pluripotent epiblast depends upon the NMD factor UPF2.
Volume: 149
Issue: 21
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Publication
23746841 | J:198412
First Author: Colak D
Year: 2013
Journal: Cell
Title: Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay.
Volume: 153
Issue: 6
Pages: 1252-65
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Publication
27149095 | J:232557
First Author: Fanourgakis G
Year: 2016
Journal: PLoS Genet
Title: Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.
Volume: 12
Issue: 5
Pages: e1005857
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Publication
17000771 | J:117588
First Author: Banihashemi L
Year: 2006
Journal: Mol Cell Biol
Title: Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay.
Volume: 26
Issue: 23
Pages: 8743-54
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Publication
22246437 | J:348672
First Author: Zheng S
Year: 2012
Journal: Nat Neurosci
Title: PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.
Volume: 15
Issue: 3
Pages: 381-8, S1
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Publication
32710818 | J:297779
First Author: Lin L
Year: 2020
Journal: Neuron
Title: Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.
Volume: 107
Issue: 6
Pages: 1180-1196.e8
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Publication
27149259 | J:232556
First Author: Bao J
Year: 2016
Journal: PLoS Genet
Title: UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.
Volume: 12
Issue: 5
Pages: e1005863
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Publication
38697111 | J:348634
     
First Author: Lin L
Year: 2024
Journal: Neuron
Title: Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size.
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Publication
30617251 | J:274242
First Author: Morgan M
Year: 2019
Journal: Cell Res
Title: A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.
Volume: 29
Issue: 3
Pages: 221-232
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Publication
22503102 | J:188025
First Author: Cho H
Year: 2012
Journal: Mol Cell
Title: Staufen1-mediated mRNA decay functions in adipogenesis.
Volume: 46
Issue: 4
Pages: 495-506
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Publication
33899734 | J:306384
   
First Author: Terrey M
Year: 2021
Journal: Elife
Title: Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology.
Volume: 10
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Publication
25770585 | J:222980
First Author: Li T
Year: 2015
Journal: EMBO J
Title: Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay.
Volume: 34
Issue: 12
Pages: 1630-47
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Protein
Q810R2
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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HT Experiment
E-GEOD-58405 | Upf2 in NMD pathway
Series Id: GSE58405
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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