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Search results 1 to 100 out of 111 for Upf3a

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
65110 | UPF3A
Type: gene
Organism: human
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Gene
100492664 | upf3a
Type: gene
Organism: frog, western clawed
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Gene
607836 | UPF3A
Type: gene
Organism: dog, domestic
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Gene
452689 | UPF3A
Type: gene
Organism: chimpanzee
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Gene
529442 | UPF3A
Type: gene
Organism: cattle
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Gene
418734 | UPF3A
Type: gene
Organism: chicken
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Gene
566608 | upf3a
Type: gene
Organism: zebrafish
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Gene
716601 | UPF3A
Type: gene
Organism: macaque, rhesus
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Gene
361176 | Upf3a
Type: gene
Organism: rat
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Protein Domain
IPR034978 | UPF3A
Type: Family
Description: UPF3A promotes nonsense-mediated mRNA decay (NMD) and regulates translation efficiency. It associates with the nuclear exon junction complex (EJC) and serves as link between the EJC core and NMD machinery []. It is a nucleocytoplasmic shuttling protein that associates selectively with spliced beta-globin mRNA in vivo []. Like other UPF3 proteins, UPF3A contains nuclear import and export signals, and a conserved Smg4_UPF3 domain with some similarity to an RNA recognition motif (RRM).
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Protein Coding Gene
MGI:1914281 | Upf3a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
147150 | UPF3AP2
Type: gene
Organism: human
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Gene
147226 | UPF3AP1
Type: gene
Organism: human
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Gene
100422343 | UPF3AP3
Type: gene
Organism: human
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Publication
36997282 | J:353269
 
First Author: Chen C
Year: 2023
Journal: Life Sci Alliance
Title: UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells.
Volume: 6
Issue: 6
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Publication
27040500 | J:234504
First Author: Shum EY
Year: 2016
Journal: Cell
Title: The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.
Volume: 165
Issue: 2
Pages: 382-95
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Publication
16601204 | -
First Author: Kunz JB
Year: 2006
Journal: RNA
Title: Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation.
Volume: 12
Issue: 6
Pages: 1015-22
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Publication
11163187 | -
First Author: Lykke-Andersen J
Year: 2000
Journal: Cell
Title: Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.
Volume: 103
Issue: 7
Pages: 1121-31
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Protein
Q9CUH6
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: true
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Protein
Q8CCF7
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
Q9CTQ4
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
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Protein
Q3ULJ3
Organism: Mus musculus/domesticus
Length: 422  
Fragment?: false
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Publication
23821644 | J:202263
First Author: Jolly LA
Year: 2013
Journal: Hum Mol Genet
Title: The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth.
Volume: 22
Issue: 23
Pages: 4673-87
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Protein Coding Gene
MGP_CAROLIEiJ_G0030848 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914281 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033880 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032403 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033301 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032116 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032519 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021311 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031958 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:5616114
Assay Type: RT-PCR
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Stage: TS17
Assay Id: MGI:5616113
Age: embryonic day 10.0
Specimen Label: E10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5616114
Assay Type: RT-PCR
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5616113
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5616114
Assay Type: RT-PCR
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:5616113
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5616114
Assay Type: RT-PCR
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5616113
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5616114
Assay Type: RT-PCR
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5616113
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5616114
Assay Type: RT-PCR
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5616113
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5615962
Age: postnatal day 2
Specimen Label: S4 P2
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615962
Age: postnatal day 8
Specimen Label: S4 P8
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615962
Age: postnatal adult
Specimen Label: S4 Adult
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S11A Cerebellum
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S11A Cerebellum Upf3b/Stau1/Upf3a
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S11B left
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615962
Age: postnatal adult
Specimen Label: S3 Cortex
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5615974
Age: embryonic day 18.5
Specimen Label: S6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S10
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S10 Upf3b/Stau1/Upf3a
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5615962
Age: embryonic day 14.5
Note: Low expression levels were detected across the telencephalic wall.
Specimen Label: 1Ai
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5615974
Age: embryonic day 14.5
Note: Low expression levels were detected in the telencephalic wall.
Specimen Label: 1A ii/iii
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: 2C Hippocampus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: 2C Hippocampus Upf3b/Stau1/Upf3a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615962
Age: postnatal adult
Specimen Label: S3 Hippocampus
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Widespread
Stage: TS17
Assay Id: MGI:5615962
Age: embryonic day 10.5
Specimen Label: S2 E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: 2C Hippocampal CA2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: 2C Hippocampal CA2 Upf3b/Stau1/Upf3a
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S11A Purkinje cells
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5615940
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5615974
Age: postnatal adult
Specimen Label: S11A Purkinje cells Upf3b/Stau1/Upf3a
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Widespread
Stage: TS22
Assay Id: MGI:5615962
Age: embryonic day 14.5
Specimen Label: S2 E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Pattern: Widespread
Stage: TS26
Assay Id: MGI:5615962
Age: embryonic day 18.5
Specimen Label: S2 E18.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Pattern: Widespread
Stage: TS27
Assay Id: MGI:5615962
Age: postnatal day 2
Specimen Label: S2 P2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5615962
Age: postnatal day 8
Specimen Label: S2 P8
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5615755
Assay Type: RNA in situ
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5615962
Age: postnatal adult
Specimen Label: S2 Adult
Detected: true
Specimen Num: 7
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Publication
16789828 | J:116443
First Author: Ciaudo C
Year: 2006
Journal: PLoS Genet
Title: Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.
Volume: 2
Issue: 6
Pages: e94
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Publication
22393026 | J:306228
First Author: Song HW
Year: 2012
Journal: Reproduction
Title: Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development.
Volume: 143
Issue: 5
Pages: 611-24
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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