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Search results 1 to 100 out of 105 for Usp26

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Li C
Year: 2022
Journal: Cell Death Differ
Title: The osteoprotective role of USP26 in coordinating bone formation and resorption.
Volume: 29
Issue: 6
Pages: 1123-1136
Publication
First Author: Sakai K
Year: 2019
Journal: Sci Rep
Title: Usp26 mutation in mice leads to defective spermatogenesis depending on genetic background.
Volume: 9
Issue: 1
Pages: 13757
Publication
First Author: Liu C
Year: 2021
Journal: EMBO J
Title: Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans.
Volume: 40
Issue: 13
Pages: e106864
Publication
First Author: Ning B
Year: 2017
Journal: Nat Commun
Title: USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Volume: 8
Issue: 1
Pages: 349
Publication
First Author: Lin YW
Year: 2011
Journal: Int J Androl
Title: Localization of ubiquitin specific protease 26 at blood-testis barrier and near Sertoli cell-germ cell interface in mouse testes.
Volume: 34
Issue: 5 Pt 2
Pages: e368-77
Publication
First Author: Tian H
Year: 2019
Journal: Biol Reprod
Title: Disruption of ubiquitin specific protease 26 gene causes male subfertility associated with spermatogenesis defects in mice†.
Volume: 100
Issue: 4
Pages: 1118-1128
Publication
First Author: Felipe-Medina N
Year: 2019
Journal: Chromosoma
Title: Ubiquitin-specific protease 26 (USP26) is not essential for mouse gametogenesis and fertility.
Volume: 128
Issue: 3
Pages: 237-247
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:1933333
Assay Type: RT-PCR
Annotation Date: 2022-10-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7365242
Age: postnatal adult
Image: 8
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1933333
Assay Type: RT-PCR
Annotation Date: 2022-10-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7365242
Age: postnatal adult
Image: 8
Specimen Label: KO
Detected: true
Specimen Num: 2
Publication  
First Author: Hou JB
Year: 2021
Journal: Oxid Med Cell Longev
Title: Ubiquitin-Specific Protease 29 Exacerbates Cerebral Ischemia-Reperfusion Injury in Mice.
Volume: 2021
Pages: 6955628
Publication
First Author: Shin YH
Year: 2010
Journal: PLoS Genet
Title: Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis.
Volume: 6
Issue: 11
Pages: e1001190
Publication
First Author: Kogo H
Year: 2012
Journal: Genes Cells
Title: HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes.
Volume: 17
Issue: 6
Pages: 439-54
Publication
First Author: Kazi S
Year: 2022
Journal: FASEB J
Title: MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.
Volume: 36
Issue: 9
Pages: e22479
Publication
First Author: Lu Y
Year: 2019
Journal: Biol Reprod
Title: CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†.
Volume: 101
Issue: 2
Pages: 501-511
Publication
First Author: Wang PJ
Year: 2001
Journal: Nat Genet
Title: An abundance of X-linked genes expressed in spermatogonia.
Volume: 27
Issue: 4
Pages: 422-6
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Lahav-Baratz S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.
Volume: 482
Issue: 1
Pages: 106-111
Publication
First Author: Typas D
Year: 2015
Journal: Nucleic Acids Res
Title: The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.
Volume: 43
Issue: 14
Pages: 6919-33
Publication
First Author: Dirac AM
Year: 2010
Journal: Mol Cancer Res
Title: The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.
Volume: 8
Issue: 6
Pages: 844-54
Interaction Experiment
Description: USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.
Allele
Name: ubiquitin specific peptidase 26; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Interaction Experiment
Description: USP26 deubiquitinates androgen receptor (AR) in the maintenance of sperm maturation and spermatogenesis through the androgen receptor signaling pathway.
Publication
First Author: Wang J
Year: 2020
Journal: Adv Clin Exp Med
Title: USP26 deubiquitinates androgen receptor (AR) in the maintenance of sperm maturation and spermatogenesis through the androgen receptor signaling pathway.
Volume: 29
Issue: 10
Pages: 1153-1160
DO Term
Protein
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
Publication
First Author: Huang X
Year: 2011
Journal: Mol Cell
Title: Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.
Volume: 42
Issue: 4
Pages: 511-23
Protein Domain
Type: Homologous_superfamily
Description: This pleckstrin homology (PH)-like domain can be found at the N terminus of some ubiquitin carboxyl-terminal hydrolases, including USP26, USP29 and USP37. USP37 antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), resulting in promoting S phase entry []. USP26 is a regulator of androgen receptor (AR) signaling []. Both USP26 and USP37 are critical for double-strand breaks repair by homologous recombination []. USP29 plays a role in apoptosis and oxidative stress [].PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner []. They share little sequence conservation, but all have a common fold, which is electrostatically polarized.
Protein Domain
Type: Domain
Description: This entry represents a pleckstrin homology (PH)-like domain found at the N terminus of some ubiquitin carboxyl-terminal hydrolases, including USP26, USP29 and USP37. USP37 antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), resulting in promoting S phase entry []. USP26 is a regulator of androgen receptor (AR) signaling []. Both USP26 and USP37 are critical for double-strand breaks repair by homologous recombination []. USP29 plays a role in apoptosis and oxidative stress [].PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner []. They share little sequence conservation, but all have a common fold, which is electrostatically polarized.
Protein
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: true
Publication
First Author: Liu J
Year: 2011
Journal: EMBO J
Title: JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress.
Volume: 30
Issue: 5
Pages: 846-58
Publication
First Author: Schweitzer K
Year: 2015
Journal: Biochim Biophys Acta
Title: CSN-associated USP48 confers stability to nuclear NF-ĪŗB/RelA by trimming K48-linked Ub-chains.
Volume: 1853
Issue: 2
Pages: 453-69
Publication
First Author: Luo M
Year: 2008
Journal: Genetics
Title: UBIQUITIN-SPECIFIC PROTEASE 26 is required for seed development and the repression of PHERES1 in Arabidopsis.
Volume: 180
Issue: 1
Pages: 229-36
Publication
First Author: Sridhar VV
Year: 2007
Journal: Nature
Title: Control of DNA methylation and heterochromatic silencing by histone H2B deubiquitination.
Volume: 447
Issue: 7145
Pages: 735-8
Protein Domain
Type: Domain
Description: This entry contains the ubiquitin-like domain of ubiquitin-specific peptidase 48 (USP48; MEROPS identifier C19.068). In animals, USP48 is found in the nucleus where it trims long Lys48-linked free and substrate-anchored ubiquitin-chains, rather than completely disassembling them; a catalytic property only shared with ataxin-3 and otubain-1. USP48 ubiquitin-chain-trimming activity is regulated by casein-kinase-2-mediated phosphorylation in response to cytokine-stimulation. USP48 controls the turnover of activated NF-kB/RelA in the nucleus together with the CSN and contributes to a timely control of immune responses [].In plants the homologue of USP48 is known as USP26, which should not be confused with USP26 from mammals. USP26 deubiquitinates histone H2B and is required for heterochromatin silencing [, ].Ubiquitin carboxyl-terminal hydrolases (UCH) () []are thiol proteases that recognise and hydrolyse the peptide bond at the C-terminal glycine of ubiquitin. These enzymes are involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. The deubiquitinsing proteases can be split into 2 size ranges, 20-30kDa() and 100-200kDa []: the second class consist of large proteins (800 to 2000 residues) that belong to the peptidase family C19, and this group is currently represented by yeast UBP1 [].
Protein Domain
Type: Domain
Description: Ubiquitin carboxyl-terminal hydrolases (UCH) () []are thiol proteases that recognise and hydrolyse the peptide bond at the C-terminal glycine of ubiquitin. These enzymes are involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. The deubiquitinsing proteases can be split into 2 size ranges, 20-30kDa() and 100-200kDa []: the second class consist of large proteins (800 to 2000 residues) that belong to the peptidase family C19, and this group is currently represented by yeast UBP1 []. This entry contains the peptidase domain for ubiquitin-specific peptidase 48 (USP48; MEROPS identifier C19.068). In animals, USP48 is found in the nucleus where it trims long Lys48-linked free and substrate-anchored ubiquitin-chains, rather than completely disassembling them; a catalytic property only shared with ataxin-3 and otubain-1. USP48 ubiquitin-chain-trimming activity is regulated by casein-kinase-2-mediated phosphorylation in response to cytokine-stimulation. USP48 controls the turnover of activated NF-kB/RelA in the nucleus together with the CSN and contributes to a timely control of immune responses [].In plants, the gene name is USP26, which should not be confused with USP26 from mammals. USP26 deubiquitinates histone H2B and is required for heterochromatin silencing [].
Protein
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
Publication
First Author: Tobias JW
Year: 1991
Journal: J Biol Chem
Title: Cloning and functional analysis of the ubiquitin-specific protease gene UBP1 of Saccharomyces cerevisiae.
Volume: 266
Issue: 18
Pages: 12021-8
Protein
Organism: Mus musculus/domesticus
Length: 869  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1052  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 979  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 979  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1036  
Fragment?: false