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Search results 1 to 97 out of 97 for Usp5

0.029s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
8078 | USP5
Type: gene
Organism: human
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Gene
100144735 | usp5
Type: gene
Organism: frog, western clawed
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Gene
297593 | Usp5
Type: gene
Organism: rat
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Gene
486718 | USP5
Type: gene
Organism: dog, domestic
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Gene
451798 | USP5
Type: gene
Organism: chimpanzee
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Gene
505280 | USP5
Type: gene
Organism: cattle
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Gene
418290 | USP5
Type: gene
Organism: chicken
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Gene
406618 | usp5
Type: gene
Organism: zebrafish
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Gene
714032 | USP5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1347343 | Usp5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
39841822 | J:361258
First Author: Eibach Y
Year: 2025
Journal: Sci Adv
Title: The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes.
Volume: 11
Issue: 4
Pages: eado3852
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Publication
25189210 | J:217911
First Author: García-Caballero A
Year: 2014
Journal: Neuron
Title: The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity.
Volume: 83
Issue: 5
Pages: 1144-58
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Publication
30340616 | J:295635
First Author: Gadotti VM
Year: 2018
Journal: Mol Brain
Title: Disrupting USP5/Cav3.2 interactions protects female mice from mechanical hypersensitivity during peripheral inflammation.
Volume: 11
Issue: 1
Pages: 60
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Publication
27974205 | J:241711
First Author: Stemkowski P
Year: 2016
Journal: Cell Rep
Title: TRPV1 Nociceptor Activity Initiates USP5/T-type Channel-Mediated Plasticity.
Volume: 17
Issue: 11
Pages: 2901-2912
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Publication
36528652 | J:332255
First Author: Li J
Year: 2022
Journal: Nat Commun
Title: USP5-Beclin 1 axis overrides p53-dependent senescence and drives Kras-induced tumorigenicity.
Volume: 13
Issue: 1
Pages: 7799
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Protein Coding Gene
MGP_CAROLIEiJ_G0028854 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031270 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031240 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031168 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031248 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1347343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030932 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031168 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031076 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031739 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030437 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022614 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029896 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19156909 | J:150908
First Author: Tian L
Year: 2009
Journal: Mol Reprod Dev
Title: Characterization and potential function of a novel pre-implantation embryo-specific RING finger protein: TRIML1.
Volume: 76
Issue: 7
Pages: 656-64
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Publication
9445485 | J:45711
First Author: Ansari-Lari MA
Year: 1998
Journal: Genome Res
Title: Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.
Volume: 8
Issue: 1
Pages: 29-40
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Publication
23055941 | J:193640
First Author: Lo JC
Year: 2012
Journal: PLoS Genet
Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Volume: 8
Issue: 10
Pages: e1002969
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Publication
- | J:175597
     
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
25207809 | -
First Author: Song AX
Year: 2014
Journal: PLoS One
Title: A ubiquitin shuttle DC-UbP/UBTD2 reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 enzymes.
Volume: 9
Issue: 9
Pages: e107509
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Publication
19098288 | -
First Author: Dayal S
Year: 2009
Journal: J Biol Chem
Title: Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53.
Volume: 284
Issue: 8
Pages: 5030-41
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Interaction Experiment
Cai B (2021)
Description: USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3.
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Interaction Experiment
Xiao X (2023)
Description: ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
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Publication
34486483 | -
   
First Author: Cai B
Year: 2021
Journal: Autophagy
Title: USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3.
Pages: 1-15
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Publication
37208329 | -
First Author: Xiao X
Year: 2023
Journal: Nat Commun
Title: ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Volume: 14
Issue: 1
Pages: 2859
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Publication
22216260 | -
First Author: Zhang YH
Year: 2011
Journal: PLoS One
Title: Domain analysis reveals that a deubiquitinating enzyme USP13 performs non-activating catalysis for Lys63-linked polyubiquitin.
Volume: 6
Issue: 12
Pages: e29362
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Protein Domain
IPR016652 | Ubiquitinyl_hydrolase
Type: Family
Description: This entry includes a group of ubiquitinyl hydrolases, also known as ubiquitin carboxyl-terminal hydrolases, including USP13 and USP5 from animals, and Ubp14 from plants and fungi. Budding yeast Ubp14 may facilitate proteolysis by preventing unanchored ubiquitin chains from competitively inhibiting polyubiquitin-substrate binding to the 26S proteasome [, ].USP5 recognizes and recycles the unanchored polyUb chain to keep the free Ub pool stable []. USP13 is an ortholog of USP5. However, unlike USP5, USP13 exhibits a weak deubiquitinating activity preferring to Lys63-linked polyubiquitin (K63-polyUb) in a non-activation manner. It may function differently from USP5 in cellular deubiquitination processes [].
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Publication
25382750 | -
First Author: Zhang XW
Year: 2015
Journal: J Pathol
Title: UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
Volume: 235
Issue: 4
Pages: 656-67
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Publication
24211586 | -
First Author: Uhler JP
Year: 2014
Journal: Biochem Biophys Res Commun
Title: The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes.
Volume: 443
Issue: 1
Pages: 7-12
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Protein Domain
IPR039869 | UBTD1/2
Type: Family
Description: This entry represents a group of ubiquitin domain-containing proteins, including UBTD1 and UBTD2. UBTD1 regulates cellular senescence through a positive feedback loop with TP53 []. UBTD1 and UBE2D (E2 ubiquitin conjugating enzyme) have been shown to form a stable, stoichiometric complex []. UBTD2, also known as DC-UbP, interacts with deubiquitinating enzyme USP5 and the Ub-activating enzyme UbE1 [].
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Publication
9305625 | -
First Author: Amerik AYu
Year: 1997
Journal: EMBO J
Title: In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome.
Volume: 16
Issue: 16
Pages: 4826-38
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Publication
29076578 | J:256284
First Author: VerPlank JJS
Year: 2018
Journal: Glia
Title: Impairment of protein degradation and proteasome function in hereditary neuropathies.
Volume: 66
Issue: 2
Pages: 379-395
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Publication
33658627 | J:303943
First Author: Cheung BB
Year: 2021
Journal: Oncogene
Title: A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma.
Volume: 40
Issue: 13
Pages: 2367-2381
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Publication
12686616 | -
First Author: Regelmann J
Year: 2003
Journal: Mol Biol Cell
Title: Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.
Volume: 14
Issue: 4
Pages: 1652-63
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Protein
Q3TNQ0
Organism: Mus musculus/domesticus
Length: 48  
Fragment?: true
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Protein
Q6PGH0
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
Q91WB7
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
P56399
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
Q5BKP2
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
Q3U4W8
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
J3QSN2
Organism: Mus musculus/domesticus
Length: 857  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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