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Search results 1 to 100 out of 346 for Usp9x

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: Ubiquitin-specific protease 9x (Usp9x), also known as ubiquitin carboxyl-terminal hydrolase FAF-X or FAM, is a deubiquitinase that acts as an important component in TGF-beta and bone morphogenetic protein signalling. It specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33 []. It is involved in axonal growth and neuronal cell migration []. Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Homan CC
Year: 2014
Journal: Am J Hum Genet
Title: Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growth.
Volume: 94
Issue: 3
Pages: 470-8
Publication
First Author: Stegeman S
Year: 2013
Journal: PLoS One
Title: Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.
Volume: 8
Issue: 7
Pages: e68287
Publication
First Author: Dupont S
Year: 2009
Journal: Cell
Title: FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.
Volume: 136
Issue: 1
Pages: 123-35
Publication
First Author: Pérez-Mancera PA
Year: 2012
Journal: Nature
Title: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Volume: 486
Issue: 7402
Pages: 266-70
Publication
First Author: Kishi K
Year: 2017
Journal: Reproduction
Title: Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice.
Volume: 154
Issue: 2
Pages: 135-143
Publication
First Author: Yoon S
Year: 2020
Journal: Neuron
Title: Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development.
Volume: 105
Issue: 3
Pages: 506-521.e7
Publication
First Author: Macrae TA
Year: 2021
Journal: Nat Commun
Title: The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development.
Volume: 12
Issue: 1
Pages: 1865
Publication
First Author: Khan OM
Year: 2018
Journal: J Clin Invest
Title: The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.
Volume: 128
Issue: 4
Pages: 1326-1337
Protein
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: true
Publication
First Author: Park Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Regulation of T cell function by the ubiquitin-specific protease USP9X via modulating the Carma1-Bcl10-Malt1 complex.
Volume: 110
Issue: 23
Pages: 9433-8
Publication
First Author: Garreau A
Year: 2017
Journal: J Immunol
Title: Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection.
Volume: 199
Issue: 8
Pages: 2758-2766
Publication  
First Author: Wang B
Year: 2022
Journal: J Clin Invest
Title: Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis.
Volume: 132
Issue: 10
Publication
First Author: Bridges CR
Year: 2017
Journal: Sci Rep
Title: USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.
Volume: 7
Issue: 1
Pages: 391
Publication
First Author: Zhang Y
Year: 2018
Journal: Biochem J
Title: Deubiquitinating enzyme USP9X regulates cellular clock function by modulating the ubiquitination and degradation of a core circadian protein BMAL1.
Volume: 475
Issue: 8
Pages: 1507-1522
Publication
First Author: Sato T
Year: 2004
Journal: Reproduction
Title: A close correlation in the expression patterns of Af-6 and Usp9x in Sertoli and granulosa cells of mouse testis and ovary.
Volume: 128
Issue: 5
Pages: 583-94
Publication
First Author: Premarathne S
Year: 2017
Journal: Sci Rep
Title: Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.
Volume: 7
Issue: 1
Pages: 8109
Publication
First Author: Hall NM
Year: 2003
Journal: Mamm Genome
Title: Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.
Volume: 14
Issue: 7
Pages: 437-47
Publication
First Author: Wrobel L
Year: 2020
Journal: Cell Rep
Title: mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR.
Volume: 33
Issue: 13
Pages: 108564
Publication
First Author: Théard D
Year: 2010
Journal: EMBO J
Title: USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.
Volume: 29
Issue: 9
Pages: 1499-509
Publication  
First Author: Noma T
Year: 2002
Journal: Mech Dev
Title: Stage- and sex-dependent expressions of Usp9x, an X-linked mouse ortholog of Drosophila Fat facets, during gonadal development and oogenesis in mice.
Volume: 119 Suppl 1
Pages: S91-5
Publication
First Author: Naik E
Year: 2014
Journal: J Exp Med
Title: Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.
Volume: 211
Issue: 10
Pages: 1947-55
Publication
First Author: Paemka L
Year: 2015
Journal: PLoS Genet
Title: Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase.
Volume: 11
Issue: 3
Pages: e1005022
Publication  
First Author: Oishi S
Year: 2016
Journal: Sci Rep
Title: Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus.
Volume: 6
Pages: 25783
Publication
First Author: Nathan JA
Year: 2008
Journal: Traffic
Title: The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X.
Volume: 9
Issue: 7
Pages: 1130-45
Publication
First Author: Agrawal P
Year: 2012
Journal: J Biol Chem
Title: Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).
Volume: 287
Issue: 25
Pages: 21164-75
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lee KH
Year: 2003
Journal: Reprod Fertil Dev
Title: Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.
Volume: 15
Issue: 1-2
Pages: 129-33
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2651453
Age: embryonic day 13.5
Specimen Label: 13.5 dpc M Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2651453
Age: embryonic day 13.5
Specimen Label: 13.5 dpc F Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2651453
Age: postnatal day 1
Specimen Label: P1 M Brain
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2651453
Age: postnatal day 1
Specimen Label: P1 F Brain
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651453
Age: postnatal adult
Specimen Label: Adult M Brain
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651453
Age: postnatal adult
Specimen Label: Adult F Brain
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2651464
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651464
Age: postnatal adult
Specimen Label: XX
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651464
Age: postnatal adult
Specimen Label: XY-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2651483
Age: postnatal day 1
Specimen Label: M Brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:2651483
Age: postnatal day 1
Specimen Label: M Lung
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:2651483
Age: postnatal day 1
Specimen Label: M Liver
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Male
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Male
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Male
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Male
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Female
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Female
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Female
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2451361
Assay Type: Northern blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651512
Age: postnatal adult
Specimen Label: Female
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681503
Age: postnatal day 14
Specimen Label: 14
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681503
Age: postnatal day 21
Specimen Label: 21
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681503
Age: postnatal adult
Specimen Label: A
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797225
Stage: TS25
Assay Id: MGI:2681509
Age: embryonic day 17.0
Specimen Label: 17dpc
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797226
Stage: TS26
Assay Id: MGI:2681509
Age: embryonic day 18.0
Specimen Label: 18dpc
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:2681509
Age: postnatal day 0.5
Specimen Label: 0.5dpp
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:2681509
Age: postnatal day 3.5
Specimen Label: 3.5dpp
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681509
Age: postnatal day 7.5
Specimen Label: 7.5dpp
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681509
Age: postnatal day 10.5
Specimen Label: 10.5dpp
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681509
Age: postnatal day 21
Specimen Label: 21dpp
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681509
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681509
Age: postnatal adult
Specimen Label: XXSxr
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2681509
Age: postnatal adult
Specimen Label: XOSxr
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5446738
Assay Type: Western blot
Annotation Date: 2014-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5602828
Age: embryonic day 11.5
Image: 1
Specimen Label: male E11.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5446738
Assay Type: Western blot
Annotation Date: 2014-10-25
Strength: Present
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5602828
Age: embryonic day 11.5
Image: 1
Specimen Label: female E11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5446738
Assay Type: Western blot
Annotation Date: 2014-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:5602828
Age: embryonic day 13.5
Image: 1
Specimen Label: male E13.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5446738
Assay Type: Western blot
Annotation Date: 2014-10-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5602828
Age: embryonic day 13.5
Image: 1
Specimen Label: female E13.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5446738
Assay Type: Western blot
Annotation Date: 2014-10-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5602828
Age: embryonic day 15.5
Image: 1
Specimen Label: male E15.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5446738
Assay Type: Western blot
Annotation Date: 2014-10-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5602828
Age: embryonic day 15.5
Image: 1
Specimen Label: female E15.5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2446629
Assay Type: Northern blot
Annotation Date: 2002-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2447074
Age: embryonic day 11.5
Image: 4
Specimen Label: 11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2446629
Assay Type: Northern blot
Annotation Date: 2002-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2447074
Age: embryonic day 12.5
Image: 4
Specimen Label: 12.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2446629
Assay Type: Northern blot
Annotation Date: 2002-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:2447074
Age: embryonic day 13.5
Image: 4
Specimen Label: 13.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2446629
Assay Type: Northern blot
Annotation Date: 2002-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2447074
Age: embryonic day 14.5
Image: 4
Specimen Label: 14.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2446629
Assay Type: Northern blot
Annotation Date: 2002-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2447074
Age: embryonic day 15.5
Image: 4
Specimen Label: 15.5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2446629
Assay Type: Northern blot
Annotation Date: 2002-12-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2447074
Age: embryonic day 17.5
Image: 4
Specimen Label: 17.5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2451339
Assay Type: RT-PCR
Annotation Date: 2003-12-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2681502
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 1