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Search results 1 to 100 out of 116 for Uspl1

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0.078s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: The USPL1 peptidase (MEROPS identifier C98.001) is an isopeptidase that releases the SUMO protein from tagged proteins []. USPL1 does not release ubiquitin from conjugates []. USPL1 colocalizes with coilin in Cajal body []. RNAi knockdown of USPL1 leads to disruption of Cajal bodies, relocalization of coilin to the nucleolus and impaired cell proliferation []. These effects do not require USPL1 to be catalytically active, and further studies have shown that USPL1 plays a role in snRNA transcription by RNA polymerase II [].Cajal bodies are spherical sub-organelles of 0.3-1.0 micrometers in diameter found in the nucleus of proliferative cells such as embryonic and tumour cells, or metabolically active cells such as neurons, involved in small nuclear ribonucleoprotein (RNP) and spliceosomal small nuclear RNP biogenesis, maintenance of telomeres and processing of histone RNA.
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
Publication
First Author: Hutten S
Year: 2014
Journal: J Cell Sci
Title: A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.
Volume: 127
Issue: Pt 5
Pages: 1065-78
Protein
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1089  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1089  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1075  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 890  
Fragment?: false
Publication
First Author: Schulz S
Year: 2012
Journal: EMBO Rep
Title: Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions.
Volume: 13
Issue: 10
Pages: 930-8
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Liu H
Year: 2010
Journal: J Neurosci Res
Title: Neurodevelopmental consequences of Smn depletion in a mouse model of spinal muscular atrophy.
Volume: 88
Issue: 1
Pages: 111-22
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5708340
Age: embryonic day 14.5
Specimen Label: Wild Type E14.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:5708340
Age: postnatal day 2
Specimen Label: Wild Type P2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5708340
Age: postnatal day 5
Specimen Label: Wild Type P5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5708340
Age: embryonic day 14.5
Specimen Label: Wild Type E14.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5708340
Age: postnatal day 2
Specimen Label: Wild Type P2
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5708340
Age: postnatal day 5
Specimen Label: Wild Type P5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757724
Stage: TS24
Assay Id: MGI:5824841
Age: embryonic day 16.0
Image: 6
Specimen Label: E16 control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:5824841
Age: postnatal day 1
Image: 6
Specimen Label: P1 control
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824841
Age: postnatal day 7
Image: 6
Specimen Label: P7 control
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824841
Age: postnatal day 13
Image: 6
Specimen Label: P13 control
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757724
Stage: TS24
Assay Id: MGI:5824851
Age: embryonic day 16.0
Image: S2
Specimen Label: E16 control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:5824851
Age: postnatal day 1
Image: S2
Specimen Label: P1 control
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824851
Age: postnatal day 7
Image: S2
Specimen Label: P7 control
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824851
Age: postnatal day 13
Image: S2
Specimen Label: P13 control
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5824693
Assay Type: Western blot
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824865
Age: postnatal day 13
Image: S4
Specimen Label: Control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5925270
Age: embryonic day 0.5
Image: 5
Specimen Label: Zy
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5925270
Age: embryonic day 1.0
Image: 5
Specimen Label: 2c
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360633
Stage: TS03
Assay Id: MGI:5925270
Age: embryonic day 2.5
Image: 5
Specimen Label: 4/8c
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5925270
Age: embryonic day 3.0
Image: 5
Specimen Label: Mo
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5925270
Age: embryonic day 3.5
Image: 5
Specimen Label: Bl
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5925270
Age: postnatal
Image: 5
Specimen Label: MII
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5824693
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3579228
Pattern: Ubiquitous
Stage: TS28
Assay Id: MGI:5824869
Age: postnatal day 13
Image: S4AI
Note: Ubiquitous cytoplasmic expression.
Specimen Label: S4AI
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5824693
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Ubiquitous
Stage: TS28
Assay Id: MGI:5824869
Age: postnatal day 13
Image: S4AI
Note: Ubiquitous cytoplasmic expression with preference of the grey matter.
Specimen Label: S4AI
Detected: true
Specimen Num: 1
Publication
First Author: Bäumer D
Year: 2009
Journal: PLoS Genet
Title: Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.
Volume: 5
Issue: 12
Pages: e1000773
Publication  
First Author: Cui W
Year: 2016
Journal: Sci Rep
Title: Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Volume: 6
Pages: 37396
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load