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Search results 1 to 100 out of 115 for Uspl1

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Hits by Strain

Type Details Score
Gene
10208 | USPL1
Type: gene
Organism: human
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Gene
100379747 | uspl1
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR033505 | USPL1
Type: Family
Description: The USPL1 peptidase (MEROPS identifier C98.001) is an isopeptidase that releases the SUMO protein from tagged proteins []. USPL1 does not release ubiquitin from conjugates []. USPL1 colocalizes with coilin in Cajal body []. RNAi knockdown of USPL1 leads to disruption of Cajal bodies, relocalization of coilin to the nucleolus and impaired cell proliferation []. These effects do not require USPL1 to be catalytically active, and further studies have shown that USPL1 plays a role in snRNA transcription by RNA polymerase II [].Cajal bodies are spherical sub-organelles of 0.3-1.0 micrometers in diameter found in the nucleus of proliferative cells such as embryonic and tumour cells, or metabolically active cells such as neurons, involved in small nuclear ribonucleoprotein (RNP) and spliceosomal small nuclear RNP biogenesis, maintenance of telomeres and processing of histone RNA.
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Gene
288447 | Uspl1
Type: gene
Organism: rat
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Gene
486019 | USPL1
Type: gene
Organism: dog, domestic
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Gene
467254 | USPL1
Type: gene
Organism: chimpanzee
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Gene
788351 | USPL1
Type: gene
Organism: cattle
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Gene
395436 | USPL1
Type: gene
Organism: chicken
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Gene
445403 | uspl1
Type: gene
Organism: zebrafish
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Gene
721890 | USPL1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2442342 | Uspl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
D6RI24
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Publication
24413172 | -
First Author: Hutten S
Year: 2014
Journal: J Cell Sci
Title: A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.
Volume: 127
Issue: Pt 5
Pages: 1065-78
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Protein
D3Z5G1
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: true
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Protein
Q3ULM6
Organism: Mus musculus/domesticus
Length: 1089  
Fragment?: false
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Protein
E9QLC6
Organism: Mus musculus/domesticus
Length: 1089  
Fragment?: false
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Protein
D3YW34
Organism: Mus musculus/domesticus
Length: 1075  
Fragment?: false
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Protein
A0A0R4J1P9
Organism: Mus musculus/domesticus
Length: 890  
Fragment?: false
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Publication
22878415 | -
First Author: Schulz S
Year: 2012
Journal: EMBO Rep
Title: Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions.
Volume: 13
Issue: 10
Pages: 930-8
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Publication
19642194 | J:154795
First Author: Liu H
Year: 2010
Journal: J Neurosci Res
Title: Neurodevelopmental consequences of Smn depletion in a mouse model of spinal muscular atrophy.
Volume: 88
Issue: 1
Pages: 111-22
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Protein Coding Gene
MGP_CAROLIEiJ_G0028050 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030400 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030096 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2442342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024616 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029048 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5708340
Age: embryonic day 14.5
Specimen Label: Wild Type E14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:5708340
Age: postnatal day 2
Specimen Label: Wild Type P2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5708340
Age: postnatal day 5
Specimen Label: Wild Type P5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5708340
Age: embryonic day 14.5
Specimen Label: Wild Type E14.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5708340
Age: postnatal day 2
Specimen Label: Wild Type P2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5708301
Assay Type: RT-PCR
Annotation Date: 2016-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5708340
Age: postnatal day 5
Specimen Label: Wild Type P5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824728
Age: postnatal day 13
Image: 6
Specimen Label: Control 4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5824729
Age: postnatal day 13
Image: 6
Specimen Label: Control 4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5824840
Assay Type: RT-PCR
Annotation Date: 2017-02-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5824731
Age: postnatal day 13
Image: 6
Specimen Label: Control 4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757724
Stage: TS24
Assay Id: MGI:5824841
Age: embryonic day 16.0
Image: 6
Specimen Label: E16 control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:5824841
Age: postnatal day 1
Image: 6
Specimen Label: P1 control
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824841
Age: postnatal day 7
Image: 6
Specimen Label: P7 control
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5824727
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824841
Age: postnatal day 13
Image: 6
Specimen Label: P13 control
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757724
Stage: TS24
Assay Id: MGI:5824851
Age: embryonic day 16.0
Image: S2
Specimen Label: E16 control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:5824851
Age: postnatal day 1
Image: S2
Specimen Label: P1 control
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824851
Age: postnatal day 7
Image: S2
Specimen Label: P7 control
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5824716
Assay Type: RT-PCR
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824851
Age: postnatal day 13
Image: S2
Specimen Label: P13 control
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5824693
Assay Type: Western blot
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:5824865
Age: postnatal day 13
Image: S4
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5925270
Age: embryonic day 0.5
Image: 5
Specimen Label: Zy
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5925270
Age: embryonic day 1.0
Image: 5
Specimen Label: 2c
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360633
Stage: TS03
Assay Id: MGI:5925270
Age: embryonic day 2.5
Image: 5
Specimen Label: 4/8c
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5925270
Age: embryonic day 3.0
Image: 5
Specimen Label: Mo
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5925270
Age: embryonic day 3.5
Image: 5
Specimen Label: Bl
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5919961
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5925270
Age: postnatal
Image: 5
Specimen Label: MII
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5824693
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3579228
Pattern: Ubiquitous
Stage: TS28
Assay Id: MGI:5824869
Age: postnatal day 13
Image: S4AI
Note: Ubiquitous cytoplasmic expression.
Specimen Label: S4AI
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5824693
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Ubiquitous
Stage: TS28
Assay Id: MGI:5824869
Age: postnatal day 13
Image: S4AI
Note: Ubiquitous cytoplasmic expression with preference of the grey matter.
Specimen Label: S4AI
Detected: true
Specimen Num: 1
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Publication
20019802 | J:161744
First Author: Bäumer D
Year: 2009
Journal: PLoS Genet
Title: Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.
Volume: 5
Issue: 12
Pages: e1000773
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Publication
27869233 | J:244597
 
First Author: Cui W
Year: 2016
Journal: Sci Rep
Title: Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Volume: 6
Pages: 37396
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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