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Search results 1 to 100 out of 145 for Vac14

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
100216224 | vac14
Type: gene
Organism: frog, western clawed
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Gene
55697 | VAC14
Type: gene
Organism: human
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Gene
447912 | vac14
Type: gene
Organism: zebrafish
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Gene
307842 | Vac14
Type: gene
Organism: rat
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Gene
489717 | VAC14
Type: gene
Organism: dog, domestic
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Gene
454220 | VAC14
Type: gene
Organism: chimpanzee
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Gene
533202 | VAC14
Type: gene
Organism: cattle
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Gene
708741 | VAC14
Type: gene
Organism: macaque, rhesus
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Gene
415678 | VAC14
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:2157980 | Vac14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR026825 | Vac14
Type: Family
Description: Vac14 is a component of the PI(3,5)P2 regulatory complex, which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) []. This complex is composed of Atg18, Fig4, Fab1, Vac14 and Vac7 in yeast. In mammals it consists of PIKfyve, FIG4 and VAC14. Fab1/PIKfyve (Fab1 in yeast and PIKfyve in mammals) is a kinase that converts PI(3)P into PI(3,5)P2 by phosphorylation at the 5-position; conversely Fig4 dephosphorylates PI(3,5)P2 back to PI(3)P. Vac14 is a scaffolding adaptor protein whose multimerisation is a prerequisite step for PI(3,5)P2 complex assembly and function [].
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Publication
19037259 | J:142703
First Author: Jin N
Year: 2008
Journal: EMBO J
Title: VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse.
Volume: 27
Issue: 24
Pages: 3221-34
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Publication
17956977 | J:127106
First Author: Zhang Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.
Volume: 104
Issue: 44
Pages: 17518-23
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Publication
15542851 | J:95120
First Author: Sbrissa D
Year: 2004
Journal: Mol Cell Biol
Title: A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.
Volume: 24
Issue: 23
Pages: 10437-47
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Protein
Q8K279
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Protein
Q80WQ2
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: false
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Protein
Q8CCX6
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
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Protein
Q8C6J5
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
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Protein
A0A1D5RLN5
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Protein
A0A1D5RLY2
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Gene
100130894 | VAC14-AS1
Type: gene
Organism: human
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Publication
23389034 | -
First Author: Alghamdi TA
Year: 2013
Journal: J Biol Chem
Title: Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
Volume: 288
Issue: 13
Pages: 9363-72
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Publication
22842785 | J:188700
First Author: Zhang Y
Year: 2012
Journal: EMBO J
Title: Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)Pâ‚‚ and PI(5)P.
Volume: 31
Issue: 16
Pages: 3442-56
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Publication
- | J:81516
     
First Author: Bronson R
Year: 2003
Journal: MGI Direct Data Submission
Title: Infantile gliosis (ingls) a new spontaneous mutation in the mouse. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine
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Publication
24600036 | J:210019
First Author: Cai X
Year: 2014
Journal: J Immunol
Title: PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3.
Volume: 192
Issue: 7
Pages: 3383-9
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Publication
19793721 | J:154296
First Author: Ferguson CJ
Year: 2009
Journal: Hum Mol Genet
Title: Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.
Volume: 18
Issue: 24
Pages: 4868-78
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Publication
23047693 | J:190368
First Author: Zolov SN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.
Volume: 109
Issue: 43
Pages: 17472-7
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Protein Coding Gene
MGP_CAROLIEiJ_G0031560 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2157980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034618 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033136 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033882 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034028 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033928 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032839 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023159 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032678 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11889142 | J:75446
First Author: Bonangelino CJ
Year: 2002
Journal: J Cell Biol
Title: Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.
Volume: 156
Issue: 6
Pages: 1015-28
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GXD Expression
GXD Expression
     
Probe: MGI:1331964
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1331965
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1331964
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1331965
Age: embryonic day 7.5
Specimen Label: 10x
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1331964
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1331965
Age: embryonic day 7.5
Specimen Label: 100x
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1331964
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1331965
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1331964
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1331965
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1331964
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1331965
Age: embryonic day 7.5
Specimen Label: 100x
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:456759
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526702
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:456759
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4829145
Age: embryonic day 14.5
Image: euxassay_007286_11
Specimen Label: euxassay_007286_11
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:456759
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526702
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
21655088 | J:173446
First Author: Lenk GM
Year: 2011
Journal: PLoS Genet
Title: Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J.
Volume: 7
Issue: 6
Pages: e1002104
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Publication
26950892 | J:236650
First Author: Li X
Year: 2016
Journal: Nat Cell Biol
Title: A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.
Volume: 18
Issue: 4
Pages: 404-17
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Protein
Q8C907
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
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Publication
25471590 | J:218853
First Author: Cao M
Year: 2014
Journal: J Neurosci
Title: Upregulation of Parkin in endophilin mutant mice.
Volume: 34
Issue: 49
Pages: 16544-9
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Publication
29187380 | J:257575
First Author: Mayer L
Year: 2018
Journal: Blood
Title: Nbeal2 interacts with Dock7, Sec16a, and Vac14.
Volume: 131
Issue: 9
Pages: 1000-1011
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Publication
27008179 | J:269748
   
First Author: Mironova YA
Year: 2016
Journal: Elife
Title: PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms.
Volume: 5
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Publication
22696681 | J:198883
First Author: Bridges D
Year: 2012
Journal: Mol Biol Cell
Title: Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.
Volume: 23
Issue: 15
Pages: 2955-62
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Publication
- | J:72400
       
First Author: Mouse Genome Sequence and Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Mouse Genome Sequence Project Annotation
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Publication
9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Gene
447315 | vac14.L
Type: gene
Organism: frog, African clawed
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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