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Search results 1 to 100 out of 100 for Vapa

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kirmiz M
Year: 2018
Journal: J Neurosci
Title: Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum-Plasma Membrane Junctions in Mammalian Brain Neurons.
Volume: 38
Issue: 35
Pages: 7562-7584
Publication
First Author: Sengupta S
Year: 2010
Journal: Biochim Biophys Acta
Title: Interaction between the motor protein prestin and the transporter protein VAPA.
Volume: 1803
Issue: 7
Pages: 796-804
Publication
First Author: Kirmiz M
Year: 2019
Journal: J Biol Chem
Title: Neuronal ER-plasma membrane junctions organized by Kv2-VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis.
Volume: 294
Issue: 47
Pages: 17735-17757
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Skehel PA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Mouse VAP33 is associated with the endoplasmic reticulum and microtubules.
Volume: 97
Issue: 3
Pages: 1101-6
GXD Expression    
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H; Emx1-cre
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H; Emx1-cre
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H; Emx1-cre
Detected: true
Specimen Num: 6
Publication
First Author: Ohnishi T
Year: 2014
Journal: Genes Cells
Title: Identification and characterization of a neuron-specific isoform of protrudin.
Volume: 19
Issue: 2
Pages: 97-111
Publication
First Author: Leca I
Year: 2020
Journal: PLoS Genet
Title: A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse.
Volume: 16
Issue: 11
Pages: e1009104
Publication
First Author: Kesavan G
Year: 2009
Journal: Cell
Title: Cdc42-mediated tubulogenesis controls cell specification.
Volume: 139
Issue: 4
Pages: 791-801
Publication
First Author: Cinque L
Year: 2015
Journal: Nature
Title: FGF signalling regulates bone growth through autophagy.
Volume: 528
Issue: 7581
Pages: 272-5
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Wright LM
Year: 2018
Journal: Mol Microbiol
Title: VapA of Rhodococcus equi binds phosphatidic acid.
Volume: 107
Issue: 3
Pages: 428-444
Allele
Name: vesicle-associated membrane protein, associated protein A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Letek M
Year: 2008
Journal: J Bacteriol
Title: Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids.
Volume: 190
Issue: 17
Pages: 5797-805
Interaction Experiment
Description: Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum-Plasma Membrane Junctions in Mammalian Brain Neurons.
Publication
First Author: Paracchini S
Year: 2006
Journal: Hum Mol Genet
Title: The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.
Volume: 15
Issue: 10
Pages: 1659-66
Protein
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
Publication
First Author: Poon MW
Year: 2011
Journal: Cell Mol Neurobiol
Title: Dyslexia-associated kiaa0319-like protein interacts with axon guidance receptor nogo receptor 1.
Volume: 31
Issue: 1
Pages: 27-35
Publication
First Author: McGrath LM
Year: 2006
Journal: Trends Mol Med
Title: Breakthroughs in the search for dyslexia candidate genes.
Volume: 12
Issue: 7
Pages: 333-41
Publication
First Author: Poelmans G
Year: 2011
Journal: Mol Psychiatry
Title: A theoretical molecular network for dyslexia: integrating available genetic findings.
Volume: 16
Issue: 4
Pages: 365-82
Protein Domain
Type: Family
Description: Several dyslexia-associated proteins have been identified: ROBO1, KIAA0319, KIAA0319L, S100B, DOCK4, FMR1, DIP2A, GTF2I, DYX1C, DCDC2, SLIT2, HMGB1 and VAPA [, ]. This entry includes KIAA0319 and KIAA0319-like (KIAA0319L) proteins. KIAA0319 is required for neuronal migration during the formation of the cerebral neocortex []. KIAA0319L has a possible role in axon guidance through interaction with nogo receptor 1 [].
Protein
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
Protein Domain
Type: Homologous_superfamily
Description: This superfamily consists of several virulence-associated proteins, mainly from Corynebacterium equii (Rhodococcus equi, Rhodococcus hoagii). R. equi is an important pulmonary pathogen of foals and is increasingly isolated from pneumonic infections and other infections in Homo sapiens immunodeficiency virus-infected patients. Both virulent and avirulent strains of R. equi differ in the possession of a virulence-associated plasmid []. The type of virulence plasmid carried is host specific; the pVapA is the plasmid type carried by R. equi isolates infecting equine. These virulence plasmids have four common regions known as the conjugation, replication, unknown function and the virulence or pathogenicity island (PAI) regions, where the members of the vap (virulence associated protein) family reside [, ]. The virulence protein VapA has been shown to inhibit the maturation of R. equi-containing phagosomes and promote intracellular bacterial survival [].
Protein Domain
Type: Family
Description: This family consists of several virulence-associated proteins, mainly from Corynebacterium equii (Rhodococcus equi, Rhodococcus hoagii). R. equi is an important pulmonary pathogen of foals and is increasingly isolated from pneumonic infections and other infections in Homo sapiens immunodeficiency virus-infected patients. Both virulent and avirulent strains of R. equi differ in the possession of a virulence-associated plasmid []. The type of virulence plasmid carried is host specific; the pVapA is the plasmid type carried by R. equi isolates infecting equine. These virulence plasmids have four common regions known as the conjugation, replication, unknown function and the virulence or pathogenicity island (PAI) regions, where the members of the vap (virulence associated protein) family reside [, ]. The virulence protein VapA has been shown to inhibit the maturation of R. equi-containing phagosomes and promote intracellular bacterial survival [].
Publication
First Author: Takai S
Year: 2000
Journal: Infect Immun
Title: DNA sequence and comparison of virulence plasmids from Rhodococcus equi ATCC 33701 and 103.
Volume: 68
Issue: 12
Pages: 6840-7
Publication
First Author: Valero-Rello A
Year: 2015
Journal: Infect Immun
Title: An Invertron-Like Linear Plasmid Mediates Intracellular Survival and Virulence in Bovine Isolates of Rhodococcus equi.
Volume: 83
Issue: 7
Pages: 2725-37
Publication
First Author: Darrah PA
Year: 2004
Journal: J Immunol
Title: Innate immune responses to Rhodococcus equi.
Volume: 173
Issue: 3
Pages: 1914-24
Publication
First Author: Mao D
Year: 2019
Journal: Autophagy
Title: VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway.
Volume: 15
Issue: 7
Pages: 1214-1233
Publication
First Author: Passantino R
Year: 2013
Journal: Biochim Biophys Acta
Title: Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis.
Volume: 1833
Issue: 3
Pages: 529-40
Protein
Organism: Mus musculus/domesticus
Length: 1048  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1081  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 985  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1085  
Fragment?: false