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Search results 1 to 100 out of 105 for Vapa

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Hits by Strain

Type Details Score
Gene
9218 | VAPA
Type: gene
Organism: human
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Gene
496796 | vapa
Type: gene
Organism: frog, western clawed
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Gene
114669839 | VAPA
Type: gene
Organism: macaque, rhesus
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Gene
58857 | Vapa
Type: gene
Organism: rat
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Gene
455288 | VAPA
Type: gene
Organism: chimpanzee
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Gene
480208 | VAPA
Type: gene
Organism: dog, domestic
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Gene
516024 | VAPA
Type: gene
Organism: cattle
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Gene
768928 | VAPA
Type: gene
Organism: chicken
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Gene
334608 | vapa
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1353561 | Vapa
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30012696 | J:264608
First Author: Kirmiz M
Year: 2018
Journal: J Neurosci
Title: Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum-Plasma Membrane Junctions in Mammalian Brain Neurons.
Volume: 38
Issue: 35
Pages: 7562-7584
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Publication
20359505 | J:165377
First Author: Sengupta S
Year: 2010
Journal: Biochim Biophys Acta
Title: Interaction between the motor protein prestin and the transporter protein VAPA.
Volume: 1803
Issue: 7
Pages: 796-804
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Publication
31594866 | J:283057
First Author: Kirmiz M
Year: 2019
Journal: J Biol Chem
Title: Neuronal ER-plasma membrane junctions organized by Kv2-VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis.
Volume: 294
Issue: 47
Pages: 17735-17757
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Protein Coding Gene
MGP_CAROLIEiJ_G0021828 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1353561 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023804 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023770 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024426 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022928 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023248 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020816 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022739 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10655491 | J:60136
First Author: Skehel PA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Mouse VAP33 is associated with the endoplasmic reticulum and microtubules.
Volume: 97
Issue: 3
Pages: 1101-6
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GXD Expression
GXD Expression
   
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H; Emx1-cre
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H; Emx1-cre
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6695103
Assay Type: Western blot
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:6695159
Age: embryonic day 18.5
Image: 6
Specimen Label: R402H/R402H; Emx1-cre
Detected: true
Specimen Num: 6
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Publication
24251978 | J:215725
First Author: Ohnishi T
Year: 2014
Journal: Genes Cells
Title: Identification and characterization of a neuron-specific isoform of protrudin.
Volume: 19
Issue: 2
Pages: 97-111
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Publication
33137126 | J:297547
First Author: Leca I
Year: 2020
Journal: PLoS Genet
Title: A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse.
Volume: 16
Issue: 11
Pages: e1009104
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Publication
19914171 | J:157396
First Author: Kesavan G
Year: 2009
Journal: Cell
Title: Cdc42-mediated tubulogenesis controls cell specification.
Volume: 139
Issue: 4
Pages: 791-801
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Publication
26595272 | J:228212
First Author: Cinque L
Year: 2015
Journal: Nature
Title: FGF signalling regulates bone growth through autophagy.
Volume: 528
Issue: 7581
Pages: 272-5
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
29205554 | -
First Author: Wright LM
Year: 2018
Journal: Mol Microbiol
Title: VapA of Rhodococcus equi binds phosphatidic acid.
Volume: 107
Issue: 3
Pages: 428-444
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Allele
Vapa<em1Smoc> | MGI:7293110
Name: vesicle-associated membrane protein, associated protein A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
18606735 | -
First Author: Letek M
Year: 2008
Journal: J Bacteriol
Title: Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids.
Volume: 190
Issue: 17
Pages: 5797-805
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Strain
MGI:6429772 | C57BL/6JSmoc-Vapa<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Interaction Experiment
Kirmiz M (2018)
Description: Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum-Plasma Membrane Junctions in Mammalian Brain Neurons.
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Publication
16600991 | J:109515
First Author: Paracchini S
Year: 2006
Journal: Hum Mol Genet
Title: The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.
Volume: 15
Issue: 10
Pages: 1659-66
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Protein
A2A786
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: true
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Protein
A2A787
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
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Publication
20697954 | -
First Author: Poon MW
Year: 2011
Journal: Cell Mol Neurobiol
Title: Dyslexia-associated kiaa0319-like protein interacts with axon guidance receptor nogo receptor 1.
Volume: 31
Issue: 1
Pages: 27-35
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Publication
16781891 | -
First Author: McGrath LM
Year: 2006
Journal: Trends Mol Med
Title: Breakthroughs in the search for dyslexia candidate genes.
Volume: 12
Issue: 7
Pages: 333-41
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Publication
20956978 | -
First Author: Poelmans G
Year: 2011
Journal: Mol Psychiatry
Title: A theoretical molecular network for dyslexia: integrating available genetic findings.
Volume: 16
Issue: 4
Pages: 365-82
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Protein Domain
IPR029865 | KIAA0319-like
Type: Family
Description: Several dyslexia-associated proteins have been identified: ROBO1, KIAA0319, KIAA0319L, S100B, DOCK4, FMR1, DIP2A, GTF2I, DYX1C, DCDC2, SLIT2, HMGB1 and VAPA [, ]. This entry includes KIAA0319 and KIAA0319-like (KIAA0319L) proteins. KIAA0319 is required for neuronal migration during the formation of the cerebral neocortex []. KIAA0319L has a possible role in axon guidance through interaction with nogo receptor 1 [].
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Protein
A2A788
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein Domain
IPR038625 | R_equi_Vir_sf
Type: Homologous_superfamily
Description: This superfamily consists of several virulence-associated proteins, mainly from Corynebacterium equii (Rhodococcus equi, Rhodococcus hoagii). R. equi is an important pulmonary pathogen of foals and is increasingly isolated from pneumonic infections and other infections in Homo sapiens immunodeficiency virus-infected patients. Both virulent and avirulent strains of R. equi differ in the possession of a virulence-associated plasmid []. The type of virulence plasmid carried is host specific; the pVapA is the plasmid type carried by R. equi isolates infecting equine. These virulence plasmids have four common regions known as the conjugation, replication, unknown function and the virulence or pathogenicity island (PAI) regions, where the members of the vap (virulence associated protein) family reside [, ]. The virulence protein VapA has been shown to inhibit the maturation of R. equi-containing phagosomes and promote intracellular bacterial survival [].
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Protein Domain
IPR008810 | R_equi_Vir
Type: Family
Description: This family consists of several virulence-associated proteins, mainly from Corynebacterium equii (Rhodococcus equi, Rhodococcus hoagii). R. equi is an important pulmonary pathogen of foals and is increasingly isolated from pneumonic infections and other infections in Homo sapiens immunodeficiency virus-infected patients. Both virulent and avirulent strains of R. equi differ in the possession of a virulence-associated plasmid []. The type of virulence plasmid carried is host specific; the pVapA is the plasmid type carried by R. equi isolates infecting equine. These virulence plasmids have four common regions known as the conjugation, replication, unknown function and the virulence or pathogenicity island (PAI) regions, where the members of the vap (virulence associated protein) family reside [, ]. The virulence protein VapA has been shown to inhibit the maturation of R. equi-containing phagosomes and promote intracellular bacterial survival [].
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Publication
11083803 | -
First Author: Takai S
Year: 2000
Journal: Infect Immun
Title: DNA sequence and comparison of virulence plasmids from Rhodococcus equi ATCC 33701 and 103.
Volume: 68
Issue: 12
Pages: 6840-7
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Publication
25895973 | -
First Author: Valero-Rello A
Year: 2015
Journal: Infect Immun
Title: An Invertron-Like Linear Plasmid Mediates Intracellular Survival and Virulence in Bovine Isolates of Rhodococcus equi.
Volume: 83
Issue: 7
Pages: 2725-37
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Publication
15265925 | J:92030
First Author: Darrah PA
Year: 2004
Journal: J Immunol
Title: Innate immune responses to Rhodococcus equi.
Volume: 173
Issue: 3
Pages: 1914-24
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Publication
30741620 | J:313400
First Author: Mao D
Year: 2019
Journal: Autophagy
Title: VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway.
Volume: 15
Issue: 7
Pages: 1214-1233
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Publication
23142642 | J:198841
First Author: Passantino R
Year: 2013
Journal: Biochim Biophys Acta
Title: Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis.
Volume: 1833
Issue: 3
Pages: 529-40
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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