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Search results 1 to 100 out of 296 for Vcp

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication      
First Author: Clemen C
Year: 2018
Journal: MGI Direct Data Submission
Title: VCP mouse model
Publication
First Author: Clemen CS
Year: 2015
Journal: Biochem Biophys Res Commun
Title: VCP and PSMF1: Antagonistic regulators of proteasome activity.
Volume: 463
Issue: 4
Pages: 1210-7
Publication
First Author: Bartolome F
Year: 2013
Journal: Neuron
Title: Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels.
Volume: 78
Issue: 1
Pages: 57-64
Publication
First Author: Wilbrey AL
Year: 2008
Journal: Mol Cell Neurosci
Title: VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S).
Volume: 38
Issue: 3
Pages: 325-40
Publication  
First Author: Shih YT
Year: 2016
Journal: Nat Commun
Title: VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation.
Volume: 7
Pages: 11020
Publication
First Author: Nalbandian A
Year: 2015
Journal: Clin Transl Sci
Title: Global gene expression profiling in R155H knock-in murine model of VCP disease.
Volume: 8
Issue: 1
Pages: 8-16
Publication
First Author: Nalbandian A
Year: 2013
Journal: PLoS One
Title: Exercise training reverses skeletal muscle atrophy in an experimental model of VCP disease.
Volume: 8
Issue: 10
Pages: e76187
Publication
First Author: Clemen CS
Year: 2018
Journal: Biochem Biophys Res Commun
Title: The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
Volume: 503
Issue: 4
Pages: 2770-2777
Publication  
First Author: Guo X
Year: 2016
Journal: Nat Commun
Title: VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Volume: 7
Pages: 12646
Publication
First Author: Nalbandian A
Year: 2015
Journal: Hum Gene Ther Methods
Title: Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.
Volume: 26
Issue: 1
Pages: 13-24
Publication  
First Author: Badadani M
Year: 2010
Journal: PLoS One
Title: VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease.
Volume: 5
Issue: 10
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Publication
First Author: Llewellyn KJ
Year: 2015
Journal: PLoS One
Title: A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy.
Volume: 10
Issue: 7
Pages: e0131995
Publication
First Author: Schulte RJ
Year: 1994
Journal: J Immunol
Title: Tyrosine phosphorylation of VCP, the mammalian homologue of the Saccharomyces cerevisiae CDC48 protein, is unusually sensitive to stimulation by sodium vanadate and hydrogen peroxide.
Volume: 153
Issue: 12
Pages: 5465-72
Publication
First Author: Koike M
Year: 2010
Journal: J Biol Chem
Title: Valosin-containing protein (VCP) in novel feedback machinery between abnormal protein accumulation and transcriptional suppression.
Volume: 285
Issue: 28
Pages: 21736-49
Publication
First Author: Hauler F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization.
Volume: 109
Issue: 48
Pages: 19733-8
Publication
First Author: Kaneko C
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a.
Volume: 300
Issue: 2
Pages: 297-304
Publication
First Author: Egerton M
Year: 1992
Journal: EMBO J
Title: VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation.
Volume: 11
Issue: 10
Pages: 3533-40
Publication
First Author: Custer SK
Year: 2010
Journal: Hum Mol Genet
Title: Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
Volume: 19
Issue: 9
Pages: 1741-55
Publication
First Author: Fusser M
Year: 2015
Journal: PLoS One
Title: Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice.
Volume: 10
Issue: 11
Pages: e0141472
Publication
First Author: Rodriguez-Ortiz CJ
Year: 2016
Journal: Am J Pathol
Title: The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.
Volume: 186
Issue: 6
Pages: 1623-34
Publication  
First Author: Yin HZ
Year: 2012
Journal: Cell Death Dis
Title: Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice.
Volume: 3
Pages: e374
Publication
First Author: Llewellyn KJ
Year: 2014
Journal: Hum Mol Genet
Title: Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease.
Volume: 23
Issue: 5
Pages: 1333-44
Publication
First Author: Nalbandian A
Year: 2012
Journal: PLoS One
Title: The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology.
Volume: 7
Issue: 9
Pages: e46308
Publication
First Author: Dai RM
Year: 2001
Journal: Nat Cell Biol
Title: Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation.
Volume: 3
Issue: 8
Pages: 740-4
Publication
First Author: Laser H
Year: 2006
Journal: Mol Biol Cell
Title: The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus.
Volume: 17
Issue: 3
Pages: 1075-84
Publication
First Author: Zhou N
Year: 2017
Journal: Aging Cell
Title: The valosin-containing protein is a novel repressor of cardiomyocyte hypertrophy induced by pressure overload.
Volume: 16
Issue: 5
Pages: 1168-1179
Publication  
First Author: Lizano P
Year: 2017
Journal: Sci Rep
Title: The valosin-containing protein is a novel mediator of mitochondrial respiration and cell survival in the heart in vivo.
Volume: 7
Pages: 46324
Publication
First Author: Peng H
Year: 2019
Journal: Biol Reprod
Title: Valosin-containing protein is associated with maintenance of meiotic arrest in mouse oocytes†.
Volume: 100
Issue: 4
Pages: 963-970
Publication
First Author: Wang B
Year: 2019
Journal: Mol Cell
Title: ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.
Volume: 74
Issue: 4
Pages: 742-757.e8
Publication
First Author: Wang HF
Year: 2011
Journal: J Clin Invest
Title: Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.
Volume: 121
Issue: 12
Pages: 4820-37
Publication
First Author: Boeddrich A
Year: 2006
Journal: EMBO J
Title: An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Volume: 25
Issue: 7
Pages: 1547-58
Publication
First Author: Ching JK
Year: 2013
Journal: Hum Mol Genet
Title: mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.
Volume: 22
Issue: 6
Pages: 1167-79
Publication
First Author: Abaan OD
Year: 2013
Journal: Exp Cell Res
Title: Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1.
Volume: 319
Issue: 1
Pages: 1-11
Publication
First Author: Lizano P
Year: 2013
Journal: Cardiovasc Res
Title: The valosin-containing protein promotes cardiac survival through the inducible isoform of nitric oxide synthase.
Volume: 99
Issue: 4
Pages: 685-93
Publication
First Author: Nalbandian A
Year: 2015
Journal: PLoS One
Title: Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy.
Volume: 10
Issue: 4
Pages: e0122888
Publication
First Author: Beirowski B
Year: 2010
Journal: Neuroscience
Title: WldS can delay Wallerian degeneration in mice when interaction with valosin-containing protein is weakened.
Volume: 166
Issue: 1
Pages: 201-11
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Glinka T
Year: 2014
Journal: Biochem J
Title: Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex.
Volume: 457
Issue: 2
Pages: 253-61
Publication
First Author: DeLaBarre B
Year: 2005
Journal: J Mol Biol
Title: Nucleotide dependent motion and mechanism of action of p97/VCP.
Volume: 347
Issue: 2
Pages: 437-52
Publication
First Author: Heo JM
Year: 2010
Journal: Mol Cell
Title: A stress-responsive system for mitochondrial protein degradation.
Volume: 40
Issue: 3
Pages: 465-80
Publication
First Author: Ye Y
Year: 2001
Journal: Nature
Title: The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.
Volume: 414
Issue: 6864
Pages: 652-6
Publication
First Author: Papadopoulos C
Year: 2017
Journal: EMBO J
Title: VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
Volume: 36
Issue: 2
Pages: 135-150
Publication
First Author: Zhao G
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Volume: 104
Issue: 21
Pages: 8785-90
Publication
First Author: Müller JM
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality.
Volume: 354
Issue: 2
Pages: 459-65
Publication
First Author: Nalbandian A
Year: 2013
Journal: Muscle Nerve
Title: A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse.
Volume: 47
Issue: 2
Pages: 260-70
Publication
First Author: Davies JM
Year: 2008
Journal: Structure
Title: Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Volume: 16
Issue: 5
Pages: 715-26
Publication
First Author: Zhao G
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation.
Volume: 106
Issue: 38
Pages: 16197-202
Publication  
First Author: Liu Y
Year: 2014
Journal: Elife
Title: USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation.
Volume: 3
Pages: e01369
Publication
First Author: Kaneko Y
Year: 2010
Journal: FEBS Lett
Title: Isolation of a point-mutated p47 lacking binding affinity to p97ATPase.
Volume: 584
Issue: 18
Pages: 3873-7
Publication
First Author: Müller JM
Year: 1999
Journal: J Biol Chem
Title: The mouse p97 (CDC48) gene. Genomic structure, definition of transcriptional regulatory sequences, gene expression, and characterization of a pseudogene.
Volume: 274
Issue: 15
Pages: 10154-62
Publication
First Author: Weihl CC
Year: 2006
Journal: Hum Mol Genet
Title: Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.
Volume: 15
Issue: 2
Pages: 189-99
Publication
First Author: DeLaBarre B
Year: 2006
Journal: Mol Cell
Title: Central pore residues mediate the p97/VCP activity required for ERAD.
Volume: 22
Issue: 4
Pages: 451-62
Publication
First Author: Weihl CC
Year: 2007
Journal: Hum Mol Genet
Title: Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.
Volume: 16
Issue: 8
Pages: 919-28
Publication
First Author: Li G
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Tyrosine phosphorylation of ATPase p97 regulates its activity during ERAD.
Volume: 375
Issue: 2
Pages: 247-51
Publication
First Author: Li G
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97.
Volume: 109
Issue: 10
Pages: 3737-41
Publication
First Author: Huang C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.
Volume: 109
Issue: 25
Pages: 9792-7
Publication
First Author: Barthelme D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase.
Volume: 110
Issue: 9
Pages: 3327-32
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6385299
Age: embryonic day 1.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6385298
Age: embryonic day 1.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6385297
Age: embryonic day 1.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3576300
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576320
Age: embryonic day 18.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3576300
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576320
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6385295
Age: postnatal
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6385291
Age: postnatal week 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6385299
Age: embryonic day 2.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6385298
Age: embryonic day 2.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6385297
Age: embryonic day 2.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6385299
Age: embryonic day 0.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6385298
Age: embryonic day 0.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6385297
Age: embryonic day 0.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:6385295
Age: postnatal
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:6385291
Age: postnatal week 4
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:6385295
Age: postnatal
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6385290
Assay Type: RT-PCR
Annotation Date: 2020-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:6385291
Age: postnatal week 4
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6385293
Assay Type: Western blot
Annotation Date: 2020-01-20
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:6385295
Age: postnatal
Detected: true
Specimen Num: 2