| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Allele |
| Name: |
V-set pre-B cell surrogate light chain 1A; targeted mutation 1, Inga-Lill Martensson |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
142
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
171
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
142
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Licence S |
| Year: |
2003 |
| Journal: |
Eur J Immunol |
| Title: |
The VpreB1 enhancer drives developmental stage-specific gene expression in vivo. |
| Volume: |
33 |
| Issue: |
4 |
| Pages: |
1117-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okabe T |
| Year: |
1992 |
| Journal: |
Eur J Immunol |
| Title: |
A pre-B- and B cell-specific DNA-binding protein, EBB-1, which binds to the promoter of the VpreB1 gene. |
| Volume: |
22 |
| Issue: |
1 |
| Pages: |
37-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yeung RS |
| Year: |
1996 |
| Journal: |
Mamm Genome |
| Title: |
The Vpreb1 and comt genes are closely linked and sublocalized to rat chromosome 11q23. |
| Volume: |
7 |
| Issue: |
3 |
| Pages: |
246-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dul JL |
| Year: |
1996 |
| Journal: |
Eur J Immunol |
| Title: |
The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development. |
| Volume: |
26 |
| Issue: |
4 |
| Pages: |
906-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Minaee S |
| Year: |
2005 |
| Journal: |
Mol Immunol |
| Title: |
Mapping and functional analysis of regulatory sequences in the mouse lambda5-VpreB1 domain. |
| Volume: |
42 |
| Issue: |
11 |
| Pages: |
1283-92 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MÃ¥rtensson A |
| Year: |
1999 |
| Journal: |
Int Immunol |
| Title: |
Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in Vpre-B1-deficient mice. |
| Volume: |
11 |
| Issue: |
3 |
| Pages: |
453-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mundt C |
| Year: |
2001 |
| Journal: |
J Exp Med |
| Title: |
Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice. |
| Volume: |
193 |
| Issue: |
4 |
| Pages: |
435-45 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mundt C |
| Year: |
2006 |
| Journal: |
Int Immunol |
| Title: |
Only VpreB1, but not VpreB2, is expressed at levels which allow normal development of B cells. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
163-72 |
|
•
•
•
•
•
|
| Allele |
| Name: |
V-set pre-B cell surrogate light chain 1B; targeted mutation 1, Takeyuki Shimizu |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okabe T |
| Year: |
1992 |
| Journal: |
Eur J Immunol |
| Title: |
Pre-B lymphocyte-specific transcriptional control of the mouse VpreB gene. |
| Volume: |
22 |
| Issue: |
1 |
| Pages: |
31-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimizu T |
| Year: |
2002 |
| Journal: |
J Immunol |
| Title: |
VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus. |
| Volume: |
168 |
| Issue: |
12 |
| Pages: |
6286-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ren W |
| Year: |
2015 |
| Journal: |
Eur J Immunol |
| Title: |
Surrogate light chain is required for central and peripheral B-cell tolerance and inhibits anti-DNA antibody production by marginal zone B cells. |
| Volume: |
45 |
| Issue: |
4 |
| Pages: |
1228-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schuh W |
| Year: |
2003 |
| Journal: |
J Immunol |
| Title: |
Cutting edge: signaling and cell surface expression of a mu H chain in the absence of lambda 5: a paradigm revisited. |
| Volume: |
171 |
| Issue: |
7 |
| Pages: |
3343-7 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vpreb1a/Vpreb1a |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vpreb1a/Vpreb1a |
| Background: |
B6.129P2-Vpreb1a |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyazaki T |
| Year: |
1999 |
| Journal: |
Int Immunol |
| Title: |
Lambda5 is required for rearrangement of the Ig kappa light chain gene in pro-B cell lines. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
1195-202 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aranburu A |
| Year: |
2023 |
| Journal: |
Front Immunol |
| Title: |
Clonal relationships of memory B cell subsets in autoimmune mice. |
| Volume: |
14 |
|
| Pages: |
1129234 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kudo A |
| Year: |
1987 |
| Journal: |
EMBO J |
| Title: |
A second gene, VpreB in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes. |
| Volume: |
6 |
| Issue: |
8 |
| Pages: |
2267-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Erlandsson L |
| Year: |
2005 |
| Journal: |
Eur J Immunol |
| Title: |
Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. |
| Volume: |
35 |
| Issue: |
6 |
| Pages: |
1969-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sabbattini P |
| Year: |
1999 |
| Journal: |
Mol Cell Biol |
| Title: |
Analysis of mice with single and multiple copies of transgenes reveals a novel arrangement for the lambda5-VpreB1 locus control region. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
671-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Szutorisz H |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. |
| Volume: |
25 |
| Issue: |
5 |
| Pages: |
1804-20 |
|
•
•
•
•
•
|
| Allele |
| Name: |
immunoglobulin lambda-like polypeptide 1; targeted mutation 1, Takeyuki Shimizu |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2652354 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-03-26 |
| Strength: |
Not Specified |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684622 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:2652390 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
PU.1 +/- |
|
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684621 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:2667798 |
| Age: |
embryonic day 13.0 |
|
|
| Specimen Label: |
Day 13 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684622 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:2667798 |
| Age: |
embryonic day 14.0 |
|
|
| Specimen Label: |
Day 14 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684623 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:2667798 |
| Age: |
embryonic day 15.0 |
|
|
| Specimen Label: |
Day 15 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684624 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:2667798 |
| Age: |
embryonic day 16.0 |
|
|
| Specimen Label: |
Day 16 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2003-07-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684625 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:2667798 |
| Age: |
embryonic day 17.0 |
|
|
| Specimen Label: |
Day 17 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684621 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:3607118 |
| Age: |
embryonic day 13.0 |
|
|
| Specimen Label: |
Day 13 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684622 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:3607118 |
| Age: |
embryonic day 14.0 |
|
|
| Specimen Label: |
Day 14 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684623 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:3607118 |
| Age: |
embryonic day 15.0 |
|
|
| Specimen Label: |
Day 15 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684624 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:3607118 |
| Age: |
embryonic day 16.0 |
|
|
| Specimen Label: |
Day 16 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684625 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:3607118 |
| Age: |
embryonic day 17.0 |
|
|
| Specimen Label: |
Day 17 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3276028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607120 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3276028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607120 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3276028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607120 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607120 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667793 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607120 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3276028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607124 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3276028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607124 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3276028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607124 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607124 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2667795 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2005-12-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3607124 |
| Age: |
postnatal week 4-5 |
|
|
| Specimen Label: |
None |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
D'Hoostelaere LA |
| Year: |
1989 |
| Journal: |
Eur J Immunol |
| Title: |
Restriction fragment analysis of V preB and lambda 5 within the genus Mus. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
37-42 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vpreb1a/Vpreb1a Vpreb1b/Vpreb1b |
| Background: |
B6.129P2-Vpreb1a Vpreb1b |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vpreb1a/Vpreb1a Vpreb1b/Vpreb1b<+> |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu X |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition. |
| Volume: |
28 |
| Issue: |
2 |
| Pages: |
472-485.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fischer U |
| Year: |
2015 |
| Journal: |
Nat Genet |
| Title: |
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. |
| Volume: |
47 |
| Issue: |
9 |
| Pages: |
1020-1029 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Igll1/Igll1 Vpreb1a/Vpreb1a Vpreb1b/Vpreb1b |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vpreb1a/Vpreb1a<+> Vpreb1b/Vpreb1b |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Knoll M |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
The non-Ig parts of the VpreB and λ5 proteins of the surrogate light chain play opposite roles in the surface representation of the precursor B cell receptor. |
| Volume: |
188 |
| Issue: |
12 |
| Pages: |
6010-7 |
|
•
•
•
•
•
|