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Search results 1 to 100 out of 119 for Vps41

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Hits by Category

Hits by Strain

Type Details Score
Gene
27072 | VPS41
Type: gene
Organism: human
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Gene
475876 | VPS41
Type: gene
Organism: dog, domestic
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Gene
463365 | VPS41
Type: gene
Organism: chimpanzee
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Gene
306991 | Vps41
Type: gene
Organism: rat
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Gene
528654 | VPS41
Type: gene
Organism: cattle
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Gene
420762 | VPS41
Type: gene
Organism: chicken
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Gene
563215 | vps41
Type: gene
Organism: zebrafish
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Gene
712457 | VPS41
Type: gene
Organism: macaque, rhesus
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Gene
100489726 | vps41
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:1929215 | Vps41
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR016902 | VPS41
Type: Family
Description: This entry represents the eukaryotic Vacuolar protein sorting-associated protein 41 (Vps41), a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex, which is essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport [, , ]. This protein interacts with Caspase-8, which plays a key role in apoptosis and development []. In humans, Vps41 variants prevent the formation of a functional HOPS complex, causing disorders such as dystonia associated with lysosomal abnormalities and neurodegenerative diseases [, , ].
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Publication
33168621 | J:307111
First Author: Burns CH
Year: 2021
Journal: Diabetes
Title: Pancreatic β-Cell-Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion.
Volume: 70
Issue: 2
Pages: 436-448
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Publication
33851776 | -
First Author: van der Welle REN
Year: 2021
Journal: EMBO Mol Med
Title: Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation.
Volume: 13
Issue: 5
Pages: e13258
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Publication
15784610 | J:184592
First Author: Aoyama M
Year: 2005
Journal: Nucleic Acids Res
Title: Simple and straightforward construction of a mouse gene targeting vector using in vitro transposition reactions.
Volume: 33
Issue: 5
Pages: e52
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Publication
33764426 | -
First Author: Sanderson LE
Year: 2021
Journal: Brain
Title: Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking.
Volume: 144
Issue: 3
Pages: 769-780
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Publication
32808683 | -
First Author: Steel D
Year: 2020
Journal: Ann Neurol
Title: Loss-of-Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities.
Volume: 88
Issue: 5
Pages: 867-877
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Publication
31194677 | J:347293
   
First Author: Lőrincz P
Year: 2019
Journal: Elife
Title: Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt.
Volume: 8
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Protein Coding Gene
MGP_CAROLIEiJ_G0018250 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_AKRJ_G0020187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1929215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019966 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0019106 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160397
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7464748
Age: embryonic day 5.5
Note: Expression distributed in both embryonic and extraembryonic regions.
Specimen Label: S2B E5.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7464571
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160399
Pattern: Widespread
Stage: TS09
Assay Id: MGI:7464810
Age: embryonic day 6.5
Note: Expression in all tissues at E5.5 and E6.5.
Specimen Label: S2A E6.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7464571
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160427
Pattern: Widespread
Stage: TS07
Assay Id: MGI:7464810
Age: embryonic day 5.5
Note: Expression in all tissues at E5.5 and E6.5.
Specimen Label: S2A E5.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:360409
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:7464748
Age: embryonic day 6.5
Note: Expression not described.
Specimen Label: S2B E6.5 mVam2-/-
Specimen Num: 4
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Protein Coding Gene
MGP_129S1SvImJ_G0020256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020002 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020643 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020085 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020672 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019300 | -
Type: protein_coding_gene
Organism: Mus pahari
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GXD Expression
GXD Expression
     
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:361197
Stage: TS07
Assay Id: MGI:7464748
Age: embryonic day 5.5
Specimen Label: S2B E5.5 mVam2-/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160399
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:7464748
Age: embryonic day 6.5
Note: Expression accumulated in epiblast.
Specimen Label: S2B E6.5 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7464571
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160397
Pattern: Widespread
Stage: TS07
Assay Id: MGI:7464810
Age: embryonic day 5.5
Note: Expression in all tissues at E5.5 and E6.5.
Specimen Label: S2A E5.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160427
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:7464748
Age: embryonic day 5.5
Note: Expression distributed in both embryonic and extraembryonic regions.
Specimen Label: S2B E5.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160429
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:7464748
Age: embryonic day 6.5
Note: Expression less abundant in visceral endoderm and extraembryonc ectoderm.
Specimen Label: S2B E6.5 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7464571
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160429
Pattern: Widespread
Stage: TS09
Assay Id: MGI:7464810
Age: embryonic day 6.5
Note: Expression in all tissues at E5.5 and E6.5.
Specimen Label: S2A E6.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7464565
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:7464748
Age: embryonic day 6.5
Note: Expression less abundant in visceral endoderm and extraembryonc ectoderm.
Specimen Label: S2B E6.5 WT
Detected: true
Specimen Num: 3
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Publication
23173123 | -
First Author: Wang L
Year: 2013
Journal: Acta Biochim Pol
Title: Vps41, a protein involved in lysosomal trafficking, interacts with caspase-8.
Volume: 60
Issue: 1
Pages: 37-42
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Publication
10944212 | -
First Author: Seals DF
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion.
Volume: 97
Issue: 17
Pages: 9402-7
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Publication
9184222 | -
First Author: Cowles CR
Year: 1997
Journal: EMBO J
Title: Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.
Volume: 16
Issue: 10
Pages: 2769-82
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Publication
37812725 | J:348149
First Author: Jain S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Adaptor protein-3 produces synaptic vesicles that release phasic dopamine.
Volume: 120
Issue: 42
Pages: e2309843120
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Publication
9111041 | -
First Author: Nakamura N
Year: 1997
Journal: J Biol Chem
Title: Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae.
Volume: 272
Issue: 17
Pages: 11344-9
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Protein
Q5KU39
Organism: Mus musculus/domesticus
Length: 853  
Fragment?: false
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Publication
22698281 | J:184591
First Author: Aoyama M
Year: 2012
Journal: Dev Cell
Title: Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway.
Volume: 22
Issue: 6
Pages: 1163-75
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Publication
14668490 | J:90042
First Author: Richardson SC
Year: 2004
Journal: Mol Biol Cell
Title: Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.
Volume: 15
Issue: 3
Pages: 1197-210
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Publication
12124942 | J:78343
First Author: Loebel DA
Year: 2002
Journal: Genesis
Title: Isolation of differentially expressed genes from wild-type and Twist mutant mouse limb buds.
Volume: 33
Issue: 3
Pages: 103-13
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Publication
11110696 | J:61187
First Author: Gwynn B
Year: 2000
Journal: Blood
Title: Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.
Volume: 96
Issue: 13
Pages: 4227-35
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Protein
Q6PES1
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Allele
Vps41<+> | MGI:2435862
   
Name: VPS41 HOPS complex subunit; wild type
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Publication
10559961 | -
First Author: Rehling P
Year: 1999
Journal: Nat Cell Biol
Title: Formation of AP-3 transport intermediates requires Vps41 function.
Volume: 1
Issue: 6
Pages: 346-53
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Allele
Vps41<Gt(OST240655)Lex> | MGI:4246747
 
Name: VPS41 HOPS complex subunit; gene trap OST240655, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Vps41<Gt(OST354919)Lex> | MGI:4291857
 
Name: VPS41 HOPS complex subunit; gene trap OST354919, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Vps41<Gt(OST362434)Lex> | MGI:4294678
 
Name: VPS41 HOPS complex subunit; gene trap OST362434, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Vps41<Gt(RRU647)Byg> | MGI:4340664
 
Name: VPS41 HOPS complex subunit; gene trap RRU647, BayGenomics
Allele Type: Gene trapped
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Allele
Vps41<Gt(9P-2)Rul> | MGI:4832471
 
Name: VPS41 HOPS complex subunit; gene trap 9P-2, H Earl Ruley
Allele Type: Gene trapped
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Allele
Vps41<tm1Ywd> | MGI:5425108
Name: VPS41 HOPS complex subunit; targeted mutation 1, Yoh Wada
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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