Type |
Details |
Score |
Protein Domain |
Type: |
Family |
Description: |
Vps52 complexes with Vps53 and Vps54 to form the Golgi-associated retrograde protein (GARP) complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network, regulating membrane trafficking events [, , ]. It is also part of the EARP (Endosome-Associated Recycling Protein) complex, involved in endocytic recycling []. |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Schindler C |
Year: |
2015 |
Journal: |
Nat Cell Biol |
Title: |
EARP is a multisubunit tethering complex involved in endocytic recycling. |
Volume: |
17 |
Issue: |
5 |
Pages: |
639-50 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
723
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
612
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
723
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
723
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Ibuchi K |
Year: |
2020 |
Journal: |
Brain Res |
Title: |
The Vps52 subunit of the GARP and EARP complexes is a novel Arf6-interacting protein that negatively regulates neurite outgrowth of hippocampal neurons. |
Volume: |
1745 |
|
Pages: |
146905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sugimoto M |
Year: |
2012 |
Journal: |
Cell Rep |
Title: |
Molecular identification of t(w5): Vps52 promotes pluripotential cell differentiation through cell-cell interactions. |
Volume: |
2 |
Issue: |
5 |
Pages: |
1363-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pérez-Victoria FJ |
Year: |
2008 |
Journal: |
Mol Biol Cell |
Title: |
Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. |
Volume: |
19 |
Issue: |
6 |
Pages: |
2350-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liewen H |
Year: |
2005 |
Journal: |
Exp Cell Res |
Title: |
Characterization of the human GARP (Golgi associated retrograde protein) complex. |
Volume: |
306 |
Issue: |
1 |
Pages: |
24-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Conibear E |
Year: |
2000 |
Journal: |
Mol Biol Cell |
Title: |
Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi. |
Volume: |
11 |
Issue: |
1 |
Pages: |
305-23 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
6 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3055070 |
Age: |
postnatal adult |
|
|
Specimen Label: |
7 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603916 |
|
Stage: |
TS16 |
Assay Id: |
MGI:3055070 |
Age: |
embryonic day 10.0 |
|
|
Specimen Label: |
12 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3055010 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-10-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160399 |
|
Stage: |
TS09 |
Assay Id: |
MGI:3055070 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
13 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dunn LC |
Year: |
1956 |
Journal: |
Genetics |
Title: |
Studies of the Genetic Variability in Wild Populations of House Mice. I. Analysis of Seven Alleles at Locus T. |
Volume: |
41 |
Issue: |
3 |
Pages: |
344-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walter L |
Year: |
1998 |
Journal: |
Genomics |
Title: |
Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex. |
Volume: |
52 |
Issue: |
3 |
Pages: |
298-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yaoi T |
Year: |
2008 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Genome-wide analysis of epigenomic alterations in fetal mouse forebrain after exposure to low doses of bisphenol A. |
Volume: |
376 |
Issue: |
3 |
Pages: |
563-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Artzt K |
Year: |
1982 |
Journal: |
Cell |
Title: |
Gene mapping within the T/t complex of the mouse. I. t-Lethal genes are nonallelic. |
Volume: |
28 |
Issue: |
3 |
Pages: |
463-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vernet C |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Genetic mapping of 10 microsatellites in the t complex region of mouse chromosome 17. |
Volume: |
9 |
Issue: |
6 |
Pages: |
472 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei J |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes. |
Volume: |
19 |
Issue: |
13 |
Pages: |
2823-2835 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abe K |
Year: |
2004 |
Journal: |
Mamm Genome |
Title: |
Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5. |
Volume: |
15 |
Issue: |
4 |
Pages: |
265-76 |
|
•
•
•
•
•
|
Allele |
Name: |
VPS52 GARP complex subunit; targeted mutation 1, Kuniya Abe |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Publication |
First Author: |
Allcock RJ |
Year: |
2000 |
Journal: |
Immunol Today |
Title: |
The mouse as a model for the effects of MHC genes on human disease. |
Volume: |
21 |
Issue: |
7 |
Pages: |
328-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
The RIKEN BioResource Center |
Year: |
2006 |
Journal: |
Unpublished |
Title: |
Information obtained from The RIKEN BioResource Center |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
|
Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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|
•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
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•
•
•
•
•
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Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
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•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
•
•
•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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•
•
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•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
•
•
•
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Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
•
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•
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Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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•
•
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•
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
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•
•
•
•
•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Gene |
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•
•
•
|
Gene |
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•
•
•
•
•
|
Gene |
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•
•
•
•
•
|
Gene |
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•
•
•
•
•
|
Gene |
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•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
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•
•
•
•
•
|
Allele |
Name: |
VPS52 GARP complex subunit; wild type |
|
|
|
•
•
•
•
•
|
Allele |
Name: |
VPS52 GARP complex subunit; t, wild 5 |
Allele Type: |
Spontaneous |
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•
•
•
•
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Allele |
Name: |
VPS52 GARP complex subunit; gene trap OST132853, Lexicon Genetics |
Allele Type: |
Gene trapped |
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Allele |
Name: |
VPS52 GARP complex subunit; targeted mutation 1, Velocigene |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
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Allele |
Name: |
VPS52 GARP complex subunit; targeted mutation 1.1, Kuniya Abe |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
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Allele |
Name: |
VPS52 GARP complex subunit; targeted mutation 1.2, Kuniya Abe |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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Allele |
Name: |
VPS52 GARP complex subunit; wild type revertant, Karen Artzt |
Allele Type: |
Spontaneous |
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Genotype |
Symbol: |
t/t Vps52/Vps52 |
Background: |
Not Specified |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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Allele |
Name: |
VPS52 GARP complex subunit; gene trap IST13264H7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
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Allele |
Name: |
VPS52 GARP complex subunit; gene trap IST13972C11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
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