Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Actin nucleation-promoting factor WASL belongs to the WASP family, whose members signal to the cytoskeleton through the Arp2/3 complex, an actin-nucleating assembly that regulates the structure and dynamics of actin filament networks at the leading edge of the cell []. WASP family members have unique N-terminal regions, followed by a central segment rich in proline, and a common C-terminal region. Their conserved C-terminal VCA domain consists of two WH2 (WASP homology 2) domains ("V"referring to either a single or multiple WH2 domains), followed by a connector domain ("C") and an acidic short extension ("A"). In the VCA region, the WH2 domain(s) bind G-actin, whereas the CA domain binds Arp2/3 complex []. Their distinct N-terminal region enables family members to activate Arp2/3 in response to different upstream signals.Interestingly, pathogen such as enteropathogenic Escherichia coli can affect host cell Arp2/3-dependent actin assembly through injecting a bacterial protein, translocated intimin receptor (Tir), into the host cell [, ]. Tir binds to the host-cell adaptor protein Nck. Nck interacts with a complex of WIP and N-WASP, resulting in the activation of the Arp2/3 complex and actin polymerisation []. Vaccinia virus can also affect actin assembly in the host cells through the interaction between its transmembrane protein A36 and host proteins, such as Grb2, Nck, WIP and N-WASP. Arp2/3-induced actin polymerisation propels the virus away from the cell surface towards neighbouring cells, enhancing the spread of infection []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Donnelly SK |
Year: |
2013 |
Journal: |
Curr Biol |
Title: |
WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization. |
Volume: |
23 |
Issue: |
11 |
Pages: |
999-1006 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garber JJ |
Year: |
2012 |
Journal: |
Infect Immun |
Title: |
Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly. |
Volume: |
80 |
Issue: |
12 |
Pages: |
4071-7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
189
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
187
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Hidalgo-Sastre A |
Year: |
2020 |
Journal: |
JCI Insight |
Title: |
Loss of Wasl improves pancreatic cancer outcome. |
Volume: |
5 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Humphries AC |
Year: |
2014 |
Journal: |
J Cell Sci |
Title: |
Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation. |
Volume: |
127 |
Issue: |
Pt 3 |
Pages: |
673-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng HC |
Year: |
2008 |
Journal: |
Nature |
Title: |
Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U). |
Volume: |
454 |
Issue: |
7207 |
Pages: |
1009-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaucher JF |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex. |
Volume: |
287 |
Issue: |
41 |
Pages: |
34646-59 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
182
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
188
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
193
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
414
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
443
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hawkins MB |
Year: |
2021 |
Journal: |
Cell |
Title: |
Latent developmental potential to form limb-like skeletal structures in zebrafish. |
Volume: |
184 |
Issue: |
4 |
Pages: |
899-911.e13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng X |
Year: |
2024 |
Journal: |
Development |
Title: |
Apical expansion of calvarial osteoblasts and suture patency is dependent on fibronectin cues. |
Volume: |
151 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Almeida-Souza L |
Year: |
2018 |
Journal: |
Cell |
Title: |
A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. |
Volume: |
174 |
Issue: |
2 |
Pages: |
325-337.e14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lommel S |
Year: |
2001 |
Journal: |
EMBO Rep |
Title: |
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. |
Volume: |
2 |
Issue: |
9 |
Pages: |
850-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jain N |
Year: |
2014 |
Journal: |
Exp Neurol |
Title: |
Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology. |
Volume: |
254 |
|
Pages: |
29-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li H |
Year: |
2019 |
Journal: |
Cancer Res |
Title: |
Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. |
Volume: |
79 |
Issue: |
9 |
Pages: |
2167-2181 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin F |
Year: |
2011 |
Journal: |
Development |
Title: |
N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination. |
Volume: |
138 |
Issue: |
7 |
Pages: |
1329-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lefever T |
Year: |
2010 |
Journal: |
J Cell Sci |
Title: |
N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways. |
Volume: |
123 |
Issue: |
Pt 1 |
Pages: |
128-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalailingam P |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation. |
Volume: |
7 |
Issue: |
1 |
Pages: |
7311 |
|
•
•
•
•
•
|
Publication |
First Author: |
Misra A |
Year: |
2010 |
Journal: |
Exp Cell Res |
Title: |
The mammalian verprolin, WIRE induces filopodia independent of N-WASP through IRSp53. |
Volume: |
316 |
Issue: |
17 |
Pages: |
2810-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rotkopf S |
Year: |
2011 |
Journal: |
Development |
Title: |
The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. |
Volume: |
138 |
Issue: |
13 |
Pages: |
2729-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao X |
Year: |
2014 |
Journal: |
PLoS Genet |
Title: |
N-wasp is required for structural integrity of the blood-testis barrier. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e1004447 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schell C |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
N-wasp is required for stabilization of podocyte foot processes. |
Volume: |
24 |
Issue: |
5 |
Pages: |
713-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wagener BM |
Year: |
2016 |
Journal: |
FASEB J |
Title: |
Neuronal Wiskott-Aldrich syndrome protein regulates TGF-β1-mediated lung vascular permeability. |
Volume: |
30 |
Issue: |
7 |
Pages: |
2557-69 |
|
•
•
•
•
•
|
Publication |
First Author: |
Novak N |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
N-WASP is required for membrane wrapping and myelination by Schwann cells. |
Volume: |
192 |
Issue: |
2 |
Pages: |
243-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jain N |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure. |
Volume: |
6 |
|
Pages: |
38109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Misra A |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
N-WASP plays a critical role in fibroblast adhesion and spreading. |
Volume: |
364 |
Issue: |
4 |
Pages: |
908-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guenin-Macé L |
Year: |
2013 |
Journal: |
J Clin Invest |
Title: |
Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation. |
Volume: |
123 |
Issue: |
4 |
Pages: |
1501-12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5661224 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-09-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5661307 |
Age: |
postnatal adult |
Image: |
1 |
|
Specimen Label: |
Brain |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5661224 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-09-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5661307 |
Age: |
postnatal adult |
Image: |
1 |
|
Specimen Label: |
Liver |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5661224 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-09-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5661307 |
Age: |
postnatal adult |
Image: |
1 |
|
Specimen Label: |
Spleen |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5699302 |
Assay Type: |
Western blot |
Annotation Date: |
2015-12-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684624 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5699324 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
Liver |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5699302 |
Assay Type: |
Western blot |
Annotation Date: |
2015-12-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689424 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5699324 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
Brain |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2769723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2769723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2853323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2845723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2845723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1869223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2854023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2762123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2762123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1832123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1832123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2851823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2851823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2760523 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2760523 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2852723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2852723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2874723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11106 |
|
Specimen Label: |
GUDMAP:11106 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5002222 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5542776 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:11135 |
|
Specimen Label: |
GUDMAP:11135 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suetsugu S |
Year: |
2007 |
Journal: |
Genes Cells |
Title: |
Male-specific sterility caused by the loss of CR16. |
Volume: |
12 |
Issue: |
6 |
Pages: |
721-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cotta-de-Almeida V |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. |
Volume: |
104 |
Issue: |
39 |
Pages: |
15424-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isaac BM |
Year: |
2010 |
Journal: |
Exp Cell Res |
Title: |
N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis. |
Volume: |
316 |
Issue: |
20 |
Pages: |
3406-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhanja A |
Year: |
2023 |
Journal: |
Elife |
Title: |
N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters. |
Volume: |
12 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Rey-Suarez I |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
WASP family proteins regulate the mobility of the B cell receptor during signaling activation. |
Volume: |
11 |
Issue: |
1 |
Pages: |
439 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamada H |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Dynamic interaction of amphiphysin with N-WASP regulates actin assembly. |
Volume: |
284 |
Issue: |
49 |
Pages: |
34244-56 |
|
•
•
•
•
•
|