Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu YH |
Year: |
2015 |
Journal: |
EMBO Rep |
Title: |
WDFY1 mediates TLR3/4 signaling by recruiting TRIF. |
Volume: |
16 |
Issue: |
4 |
Pages: |
447-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Y |
Year: |
2020 |
Journal: |
Cell Mol Immunol |
Title: |
Wdfy1 deficiency impairs Tlr3-mediated immune responses in vivo. |
Volume: |
17 |
Issue: |
9 |
Pages: |
1014-1016 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lv C |
Year: |
2022 |
Journal: |
Biochem Biophys Res Commun |
Title: |
WDFY1, a WD40 repeat protein, is not essential for spermatogenesis and male fertility in mice. |
Volume: |
596 |
|
Pages: |
71-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ning F |
Year: |
2019 |
Journal: |
J Exp Med |
Title: |
Hes1 attenuates type I IFN responses via VEGF-C and WDFY1. |
Volume: |
216 |
Issue: |
6 |
Pages: |
1396-1410 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rahman S |
Year: |
2021 |
Journal: |
Cells |
Title: |
miR-511 Deficiency Protects Mice from Experimental Colitis by Reducing TLR3 and TLR4 Responses via WD Repeat and FYVE-Domain-Containing Protein 1. |
Volume: |
11 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4881455 |
Assay Type: |
RT-PCR |
Annotation Date: |
2011-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4881508 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4881455 |
Assay Type: |
RT-PCR |
Annotation Date: |
2011-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604220 |
|
Stage: |
TS20 |
Assay Id: |
MGI:4881508 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4881455 |
Assay Type: |
RT-PCR |
Annotation Date: |
2011-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3568928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4881508 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Csf2-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4881455 |
Assay Type: |
RT-PCR |
Annotation Date: |
2011-02-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1604220 |
|
Stage: |
TS20 |
Assay Id: |
MGI:4881508 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Csf2-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5315266 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
E15.5 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5315266 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
E15.5 LTbeta-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752524 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5315266 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
E16.5 WT |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752524 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5315266 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
E16.5 Ltbeta-/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752526 |
|
Stage: |
TS26 |
Assay Id: |
MGI:5315266 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
E18.5 WT |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752526 |
|
Stage: |
TS26 |
Assay Id: |
MGI:5315266 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
E18.5 Ltbeta-/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5315266 |
Age: |
postnatal day 5 |
|
|
Specimen Label: |
p5 WT |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310985 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-04-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5315266 |
Age: |
postnatal day 5 |
|
|
Specimen Label: |
p5 Ltbeta-/- |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:685110 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-23 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603911 |
Pattern: |
Not Specified |
Stage: |
TS11 |
Assay Id: |
MGI:3828816 |
Age: |
embryonic day 7.5 |
|
Note: |
Expression is weak to non-existent. |
Specimen Label: |
E7.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:685110 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-23 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603913 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:3828816 |
Age: |
embryonic day 8.5 |
|
Note: |
Expression is weak to non-existent. |
Specimen Label: |
E8.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ouyang L |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
p39-associated Cdk5 activity regulates dendritic morphogenesis. |
Volume: |
10 |
Issue: |
1 |
Pages: |
18746 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doherty R |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Identification of in vivo roles of ErbB4-JMa and its direct nuclear signaling using a novel isoform-specific knock out mouse. |
Volume: |
12 |
Issue: |
1 |
Pages: |
17267 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeo IJ |
Year: |
2019 |
Journal: |
Mol Neurobiol |
Title: |
PRDX6 Inhibits Neurogenesis through Downregulation of WDFY1-Mediated TLR4 Signal. |
Volume: |
56 |
Issue: |
5 |
Pages: |
3132-3144 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boschen KE |
Year: |
2021 |
Journal: |
Dis Model Mech |
Title: |
Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. |
Volume: |
14 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
307
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
de Ledesma AM |
Year: |
2006 |
Journal: |
Mamm Genome |
Title: |
Two new behavioral QTLs, Emo4 and Reb1, map to mouse Chromosome 1: Congenic strains and candidate gene identification studies. |
Volume: |
17 |
Issue: |
2 |
Pages: |
111-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cui CY |
Year: |
2007 |
Journal: |
Hum Mol Genet |
Title: |
Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. |
Volume: |
16 |
Issue: |
21 |
Pages: |
2583-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boettger-Tong HL |
Year: |
2001 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes. |
Volume: |
288 |
Issue: |
5 |
Pages: |
1129-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sferruzzi-Perri AN |
Year: |
2009 |
Journal: |
Biol Reprod |
Title: |
Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice. |
Volume: |
81 |
Issue: |
1 |
Pages: |
207-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kurogi S |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. |
Volume: |
7 |
|
Pages: |
40692 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakahara M |
Year: |
2013 |
Journal: |
Mamm Genome |
Title: |
Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. |
Volume: |
24 |
Issue: |
5-6 |
Pages: |
228-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Sequence and Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Mouse Genome Sequence Project Annotation |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tamplin OJ |
Year: |
2008 |
Journal: |
BMC Genomics |
Title: |
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. |
Volume: |
9 |
|
Pages: |
511 |
|
•
•
•
•
•
|
Publication |
First Author: |
The RIKEN BioResource Center |
Year: |
2006 |
Journal: |
Unpublished |
Title: |
Information obtained from The RIKEN BioResource Center |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Araki K |
Year: |
1999 |
Journal: |
Cell Mol Biol (Noisy-le-grand) |
Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
Volume: |
45 |
Issue: |
5 |
Pages: |
737-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taniwaki T |
Year: |
2005 |
Journal: |
Dev Growth Differ |
Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
Volume: |
47 |
Issue: |
3 |
Pages: |
163-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Interaction Experiment |
Description: |
WDFY1 mediates TLR3/4 signaling by recruiting TRIF. |
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Publication |
First Author: |
He J |
Year: |
2009 |
Journal: |
Proteins |
Title: |
Membrane insertion of the FYVE domain is modulated by pH. |
Volume: |
76 |
Issue: |
4 |
Pages: |
852-60 |
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Protein Domain |
Type: |
Domain |
Description: |
WDFY1 is a novel single FYVE domain containing protein that binds phosphatidylinositol 3-phosphate (PtdIns3P or PI3P) with high specificity over other phosphoinositides. WDFY1 to early endosomes requires an intact FYVE domain and is inhibited by wortmannin, a PI3-kinase inhibitor. In addition to FYVE domain, WDFY1 harbours multiple WD-40 repeats. This entry represent the FYVE domain of WDFY1 [, ]. |
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Publication |
First Author: |
Fritzius T |
Year: |
2007 |
Journal: |
FEBS J |
Title: |
WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. |
Volume: |
274 |
Issue: |
6 |
Pages: |
1552-66 |
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