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Search results 1 to 24 out of 24 for Wdr61

0.018s

Type

Details

Score

Gene

415359 | WDR61

Type:	gene
Organism:	chicken

•

Protein Coding Gene

MGI:1917493 | Skic8

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Protein

Q5XJE5

Organism:	Mus musculus/domesticus
Length:	667
Fragment?:	false

•

Protein

Q8K2T8

Organism:	Mus musculus/domesticus
Length:	535
Fragment?:	false

•

Protein

Q6IQZ4

Organism:	Mus musculus/domesticus
Length:	82
Fragment?:	false

•

Publication

20178742 | -

First Author:	Kim J
Year:	2010
Journal:	Cell
Title:	The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.
Volume:	140
Issue:	4
Pages:	491-503

•

Publication

16491129 | -

First Author:	Moniaux N
Year:	2006
Journal:	Oncogene
Title:	The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis.
Volume:	25
Issue:	23
Pages:	3247-57

•

Publication

22419161 | -

First Author:	Marazzi I
Year:	2012
Journal:	Nature
Title:	Suppression of the antiviral response by an influenza histone mimic.
Volume:	483
Issue:	7390
Pages:	428-33

•

Publication

15791002 | -

First Author:	Zhao L
Year:	2005
Journal:	FASEB J
Title:	Expression of the Leo1-like domain of replicative senescence down-regulated Leo1-like (RDL) protein promotes senescence of 2BS fibroblasts.
Volume:	19
Issue:	6
Pages:	521-32

•

Publication

24385927 | -

First Author:	Mbogning J
Year:	2013
Journal:	PLoS Genet
Title:	The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast.
Volume:	9
Issue:	12
Pages:	e1004029

•

Protein Domain

IPR007133 | RNA_pol_II-assoc_Paf1

Type:

Family

Description:

In budding yeasts, Paf1 is part of the Paf1 complex, an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1 []. Paf1 complex is involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection []. This entry also includes Paf1 homologues from animals and plants. Human Paf1, also known as PD2 (pancreatic differentiation 2), is associated with tumorigenesis []. Human Paf1 complex (Paf1C) consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications []. Human Paf1 complex has a crucial role in the antiviral response []. Arabidopsis Paf1C related proteins such as VIP4 (Leo1), VIP5 (Rtf1), ELF7 (Paf1), ELF8 (Ctr9) and ATXR7 (Set1) are required for the induction of seed dormancy. They control both germination and flowering time [].

•

Protein Domain

IPR007149 | Leo1

Type:

Family

Description:

In budding yeasts, Leo1 is part of the Paf1 complex, an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1. Paf1 complex is involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection []. This entry also includes Leo1 homologues from animals and plants. Human Leo1, also known as RDL, is a component of the human Paf1 complex (Paf1C), which consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications []. Human Leo1 promotes senescence of 2BS fibroblasts [].Arabidopsis Paf1C related proteins such as VIP4 (Leo1), VIP5 (Rtf1), ELF7 (Paf1), ELF8 (Ctr9) and ATXR7 (Set1) are required for the induction of seed dormancy. They control both germination and flowering time [].

•

Protein Domain

IPR031101 | Ctr9

Type:

Family

Description:

This entry includes budding yeast RNA polymerase-associated protein Ctr9 and its homologues from other yeasts, animals and plants. The homologue in fission yeast is known as tetratricopeptide repeat protein 1 (Tpr1) [].Budding yeast Ctr9 is part of the Paf1 complex, an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1 []. Paf1 complex is involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection []. Human Paf1 complex (Paf1C) consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications [].Arabidopsis Paf1C related proteins such as VIP4 (Leo1), VIP5 (Rtf1), ELF7 (Paf1), ELF8 (Ctr9) and ATXR7 (Set1) are required for the induction of seed dormancy. They control both germination and flowering time [].

•

Publication

11884586 | -

First Author:	Mueller CL
Year:	2002
Journal:	Mol Cell Biol
Title:	Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.
Volume:	22
Issue:	7
Pages:	1971-80

•

Publication

1913663 | -

First Author:	Isom H
Year:	1991
Journal:	Cancer Res
Title:	Workshop report from the Division of Research Grants, National Institutes of Health. The role of chromosome rearrangements, deletions, and point mutations in cancer--a Pathology B Study Section workshop.
Volume:	51
Issue:	19
Pages:	5440-4

•

Publication

21799800 | -

First Author:	Liu Y
Year:	2011
Journal:	PLoS One
Title:	Identification of the Arabidopsis REDUCED DORMANCY 2 gene uncovers a role for the polymerase associated factor 1 complex in seed dormancy.
Volume:	6
Issue:	7
Pages:	e22241

•

Publication

12242279 | -

First Author:	Krogan NJ
Year:	2002
Journal:	Mol Cell Biol
Title:	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.
Volume:	22
Issue:	20
Pages:	6979-92

•

Publication

20363855 | -

First Author:	Park S
Year:	2010
Journal:	Plant Physiol
Title:	PLANT HOMOLOGOUS TO PARAFIBROMIN is a component of the PAF1 complex and assists in regulating expression of genes within H3K27ME3-enriched chromatin.
Volume:	153
Issue:	2
Pages:	821-31

•

Publication

20463090 | -

First Author:	Yu X
Year:	2010
Journal:	Plant Physiol
Title:	The Arabidopsis Paf1c complex component CDC73 participates in the modification of FLOWERING LOCUS C chromatin.
Volume:	153
Issue:	3
Pages:	1074-84

•

Protein Domain

IPR007852 | Cdc73/Parafibromin

Type:

Family

Description:

This entry includes Cdc73 from budding yeasts and its animal homologue, parafibromin. They are part of the Paf1 complex involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection [].In budding yeasts, Paf1 is an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1. It is required for full expression of a subset of yeast genes, particularly those responsive to signals from the Pkc1/MAP kinase cascade. The complex appears to play an essential role in RNA elongation []. Human parafibromin is a tumour suppressor that may facilitate association of 3' mRNA processing factors with actively-transcribed chromatin. It is a component of the human Paf1 complex (Paf1C), which consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications []. The Arabidopsis Cdc73 (also known as PLANT HOMOLOGOUS TO PARAFIBROMIN ,PHP) assists in regulating expression of genes within H3K27ME3-enriched chromatin []and participates in the modification of FLOWERING LOCUS C (FLC) chromatin [].

•

Protein

Q8JZM7

Organism:	Mus musculus/domesticus
Length:	531
Fragment?:	false

•

Protein

Q62018

Organism:	Mus musculus/domesticus
Length:	1173
Fragment?:	false

•

Protein

Q05DK2

Organism:	Mus musculus/domesticus
Length:	939
Fragment?:	true

•

Protein

Q05CJ7

Organism:	Mus musculus/domesticus
Length:	936
Fragment?:	true

•

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