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Search results 1 to 85 out of 85 for Wdr72

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Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
Type: gene
Organism: human
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Publication
First Author: Katsura K
Year: 2022
Journal: Sci Rep
Title: WDR72 regulates vesicle trafficking in ameloblasts.
Volume: 12
Issue: 1
Pages: 2820
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Publication  
First Author: Katsura KA
Year: 2014
Journal: Matrix Biol
Title: WDR72 models of structure and function: a stage-specific regulator of enamel mineralization.
Volume: 38
Pages: 48-58
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Publication
First Author: Auwerx H
Year: 2026
Journal: Acta Physiol (Oxf)
Title: WDR72 Is Required for Urinary Acidification and Normal H(+)-ATPase Activity in Intercalated Cells in Mice.
Volume: 242
Issue: 3
Pages: e70165
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Publication  
First Author: Liu X
Year: 2019
Journal: Biomed Pharmacother
Title: RUNX2 contributes to TGF-?1-induced expression of Wdr72 in ameloblasts during enamel mineralization.
Volume: 118
Pages: 109235
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Publication
First Author: Wang SK
Year: 2015
Journal: Mol Genet Genomic Med
Title: Critical roles for WDR72 in calcium transport and matrix protein removal during enamel maturation.
Volume: 3
Issue: 4
Pages: 302-19
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication  
First Author: Soulez M
Year: 2019
Journal: Mol Cell Biol
Title: Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models.
Volume: 39
Issue: 6
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication      
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication      
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
First Author: El-Sayed W
Year: 2009
Journal: Am J Hum Genet
Title: Mutations in the beta propeller WDR72 cause autosomal-recessive hypomaturation amelogenesis imperfecta.
Volume: 85
Issue: 5
Pages: 699-705
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Allele
Name: WD repeat domain 72; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Genotype
Symbol: Wdr72/Wdr72
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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DO Term
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Protein
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: true
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Protein Domain
Type: Family
Description: This family includes WD repeat-containing protein 7 and WD repeat-containing protein 72 (WDR7/72). The function of WDR7 is currently unknown.WD repeat-containing protein 72 (WDR72) plays a major role in the formation of tooth enamel, particularly during the maturation phase of amelogenesis, where it is essential for normal enamel matrix formation and the clearance of enamel proteins [, ]. WDR72 may also be involved in the localisation of the calcium transporter SLC24A4 to the ameloblast cell membrane. These proteins share a distinct domain architecture comprising one or two ��-propellers followed by an ��-solenoid domain , an evolutionarily conserved structure common among proteins that form membrane coat complexes, dating back to the early eukaryotic endomembrane system [].
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Protein Domain
Type: Domain
Description: This entry represents an ��-solenoid domain found in WDR72. This entry also includes WDR7, whose function is currently unknown.WD repeat-containing protein 72 (WDR72) plays a major role in the formation of tooth enamel, particularly during the maturation phase of amelogenesis, where it is essential for normal enamel matrix formation and the clearance of enamel proteins [, ]. WDR72 may also be involved in the localisation of the calcium transporter SLC24A4 to the ameloblast cell membrane. These proteins share a distinct domain architecture comprising one or two ��-propellers followed by an ��-solenoid domain , an evolutionarily conserved structure common among proteins that form membrane coat complexes, dating back to the early eukaryotic endomembrane system [].
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Publication  
First Author: Ngu J
Year: 2023
Journal: Front Physiol
Title: Na(+) and K(+) transport and maturation stage ameloblast modulation.
Volume: 14
Pages: 1124444
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Protein
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1114  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1489  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1102  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 531  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 755  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 531  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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