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Search results 1 to 78 out of 78 for Wfikkn1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kondás K
Year: 2008
Journal: J Biol Chem
Title: Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.
Volume: 283
Issue: 35
Pages: 23677-84
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7606219
Age: postnatal
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7606219
Age: postnatal
Image: 1
Specimen Label: Lung
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7606219
Age: postnatal
Image: 1
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7606219
Age: postnatal
Image: 1
Specimen Label: Kidney
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7606219
Age: postnatal
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:7606219
Age: postnatal
Image: 1
Specimen Label: Adipose tissue
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7606220
Age: postnatal
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567028
Stage: TS28
Assay Id: MGI:7606220
Age: postnatal
Image: 1
Specimen Label: Pectoralis
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914628
Stage: TS28
Assay Id: MGI:7606220
Age: postnatal
Image: 1
Specimen Label: Quadriceps
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3537528
Stage: TS28
Assay Id: MGI:7606220
Age: postnatal
Image: 1
Specimen Label: Gastrocnemius
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7606233
Age: embryonic day 9.5
Image: 6
Specimen Label: E9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7594141
Assay Type: RT-PCR
Annotation Date: 2024-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:7606233
Age: embryonic day 14.5
Image: 6
Specimen Label: E14.5
Detected: true
Specimen Num: 2
Publication
First Author: Feng S
Year: 2022
Journal: Cell
Title: Incomplete lineage sorting and phenotypic evolution in marsupials.
Volume: 185
Issue: 10
Pages: 1646-1660.e18
Publication
First Author: Parenté A
Year: 2020
Journal: FASEB J
Title: GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.
Volume: 34
Issue: 3
Pages: 4026-4040
Publication
First Author: Lee YS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.
Volume: 110
Issue: 39
Pages: E3713-22
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Kondás K
Year: 2011
Journal: Biochem Soc Trans
Title: Biological functions of the WAP domain-containing multidomain proteins WFIKKN1 and WFIKKN2.
Volume: 39
Issue: 5
Pages: 1416-20
Allele
Name: WAP, FS, Ig, KU, and NTR-containing protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Szláma G
Year: 2010
Journal: FEBS J
Title: WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.
Volume: 277
Issue: 24
Pages: 5040-50
Publication
First Author: Trexler M
Year: 2002
Journal: Biol Chem
Title: Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.
Volume: 383
Issue: 1
Pages: 223-8
Protein Domain
Type: Family
Description: WFIKKN proteins are secreted multidomain proteins containing a WAP (whey acidic protein)-, a follistatin/Kazal-, an immunoglobulin-, two Kunitz-type protease inhibitor-domains, and an NTR (netrin) domain. They have been reported to inhibit the activity of trypsin, and to bind GDF11 (growth and differentiation factor 11) and myostatin (GDF8) []. Due to the presence of multiple domains that frequently serve as protease inhibitors, WFIKKN proteins are presumed to control the action of diverse serine proteases as well as metalloproteinases [].In humans, WFIKKN1 expression is observed in pancreas, liver, thymus, kidney, testis and lung and WFIKKN2 (also known as WFIKKNRP) expression is observed in ovary, testis, pancreas, brain and lung [].
Protein
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 518  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false