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Search results 1 to 100 out of 766 for Wfs1

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0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Yamaguchi S
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein.
Volume: 325
Issue: 1
Pages: 250-6
Publication
First Author: Richard EM
Year: 2023
Journal: Cell Death Dis
Title: Wfs1(E864K) knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production.
Volume: 14
Issue: 6
Pages: 387
Publication
First Author: Matto V
Year: 2011
Journal: J Physiol Biochem
Title: Impaired striatal dopamine output of homozygous Wfs1 mutant mice in response to [K+] challenge.
Volume: 67
Issue: 1
Pages: 53-60
Publication
First Author: Kõks S
Year: 2009
Journal: Physiol Genomics
Title: Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway.
Volume: 37
Issue: 3
Pages: 249-59
Publication
First Author: Kõks S
Year: 2011
Journal: Physiol Genomics
Title: Hypothalamic gene expression profile indicates a reduction in G protein signaling in the Wfs1 mutant mice.
Volume: 43
Issue: 24
Pages: 1351-8
Publication  
First Author: Punapart M
Year: 2014
Journal: PPAR Res
Title: Effect of chronic valproic Acid treatment on hepatic gene expression profile in wfs1 knockout mouse.
Volume: 2014
Pages: 349525
Publication
First Author: Terasmaa A
Year: 2011
Journal: J Physiol Biochem
Title: Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin.
Volume: 67
Issue: 3
Pages: 381-90
Publication
First Author: Kõks S
Year: 2013
Journal: Physiol Genomics
Title: Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.
Volume: 45
Issue: 5
Pages: 182-90
Publication  
First Author: Morikawa S
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells.
Volume: 13
Pages: 849204
Publication
First Author: Tekko T
Year: 2017
Journal: PLoS One
Title: Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors.
Volume: 12
Issue: 3
Pages: e0172825
Publication
First Author: Akiyama M
Year: 2009
Journal: Diabetologia
Title: Increased insulin demand promotes while pioglitazone prevents pancreatic beta cell apoptosis in Wfs1 knockout mice.
Volume: 52
Issue: 4
Pages: 653-63
Publication  
First Author: Tein K
Year: 2015
Journal: Front Mol Neurosci
Title: Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice.
Volume: 8
Pages: 45
Publication
First Author: Ueda K
Year: 2005
Journal: Eur J Endocrinol
Title: Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic beta-cells via transcriptional activation.
Volume: 153
Issue: 1
Pages: 167-76
Publication
First Author: Kato T
Year: 2008
Journal: Neurosci Res
Title: Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder.
Volume: 61
Issue: 2
Pages: 143-58
Publication
First Author: Ishihara H
Year: 2004
Journal: Hum Mol Genet
Title: Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.
Volume: 13
Issue: 11
Pages: 1159-70
GXD Expression      
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191556
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Wfs1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191556
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Wfs1
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191556
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Wfs1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191556
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Wfs1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191556
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Wfs1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191556
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Wfs1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6186832
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191556
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Wfs1
Detected: true
Specimen Num: 7
Publication  
First Author: Tekko T
Year: 2014
Journal: Int J Dev Neurosci
Title: Initiation and developmental dynamics of Wfs1 expression in the context of neural differentiation and ER stress in mouse forebrain.
Volume: 35
Pages: 80-8
Publication
First Author: Luuk H
Year: 2008
Journal: J Comp Neurol
Title: Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome.
Volume: 509
Issue: 6
Pages: 642-60
Publication
First Author: Cryns K
Year: 2003
Journal: Histochem Cell Biol
Title: The WFS1 gene, responsible for low frequency sensorineural hearing loss and Wolfram syndrome, is expressed in a variety of inner ear cells.
Volume: 119
Issue: 3
Pages: 247-56
Publication
First Author: Inoue H
Year: 1998
Journal: Nat Genet
Title: A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome).
Volume: 20
Issue: 2
Pages: 143-8
Publication
First Author: Strom TM
Year: 1998
Journal: Hum Mol Genet
Title: Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein.
Volume: 7
Issue: 13
Pages: 2021-8
Publication
First Author: Cagalinec M
Year: 2016
Journal: PLoS Biol
Title: Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome.
Volume: 14
Issue: 7
Pages: e1002511
Publication
First Author: Abreu D
Year: 2020
Journal: Lab Invest
Title: Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival.
Volume: 100
Issue: 6
Pages: 849-862
Publication
First Author: Fonseca SG
Year: 2012
Journal: Nat Cell Biol
Title: Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion.
Volume: 14
Issue: 10
Pages: 1105-12
Publication
First Author: Zatyka M
Year: 2015
Journal: Hum Mol Genet
Title: Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.
Volume: 24
Issue: 3
Pages: 814-27
Publication
First Author: Hatanaka M
Year: 2011
Journal: Hum Mol Genet
Title: Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells.
Volume: 20
Issue: 7
Pages: 1274-84
Publication
First Author: Bonnet Wersinger D
Year: 2014
Journal: PLoS One
Title: Impairment of visual function and retinal ER stress activation in Wfs1-deficient mice.
Volume: 9
Issue: 5
Pages: e97222
Publication
First Author: Yamada T
Year: 2006
Journal: Hum Mol Genet
Title: WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
Volume: 15
Issue: 10
Pages: 1600-9
Publication
First Author: Raud S
Year: 2009
Journal: Neurosci Lett
Title: Relation between increased anxiety and reduced expression of alpha1 and alpha2 subunits of GABA(A) receptors in Wfs1-deficient mice.
Volume: 460
Issue: 2
Pages: 138-42
Publication  
First Author: Visnapuu T
Year: 2013
Journal: Behav Brain Res
Title: Evidence for impaired function of dopaminergic system in Wfs1-deficient mice.
Volume: 244
Pages: 90-9
Publication  
First Author: Ivask M
Year: 2018
Journal: Neuroscience
Title: Hippocampus and Hypothalamus RNA-sequencing of WFS1-deficient Mice.
Volume: 374
Pages: 91-103
Publication
First Author: Gorgogietas V
Year: 2023
Journal: Diabetologia
Title: GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models.
Volume: 66
Issue: 7
Pages: 1306-1321
Publication  
First Author: Reimets R
Year: 2016
Journal: Behav Brain Res
Title: Variability in the effect of antidepressants upon Wfs1-deficient mice is dependent on the drugs' mechanism of actions.
Volume: 308
Pages: 53-63
Publication
First Author: Luuk H
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Circadian rhythms and food anticipatory behavior in Wfs1-deficient mice.
Volume: 424
Issue: 4
Pages: 717-23
Publication
First Author: Tepp K
Year: 2020
Journal: Biochim Biophys Acta Gen Subj
Title: Adaptation of striated muscles to Wolframin deficiency in mice: Alterations in cellular bioenergetics.
Volume: 1864
Issue: 4
Pages: 129523
Publication
First Author: Philbrook C
Year: 2005
Journal: Exp Gerontol
Title: Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
Volume: 40
Issue: 8-9
Pages: 671-8
Publication
First Author: Kawano J
Year: 2008
Journal: J Comp Neurol
Title: Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system.
Volume: 510
Issue: 1
Pages: 1-23
Publication
First Author: Lu S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.
Volume: 111
Issue: 49
Pages: E5292-301
Publication    
First Author: Rossi G
Year: 2023
Journal: Elife
Title: MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice.
Volume: 12
Publication
First Author: Fonseca SG
Year: 2010
Journal: J Clin Invest
Title: Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells.
Volume: 120
Issue: 3
Pages: 744-55
Publication
First Author: Zatyka M
Year: 2008
Journal: Hum Mol Genet
Title: Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress.
Volume: 17
Issue: 2
Pages: 190-200
Publication
First Author: Riggs AC
Year: 2005
Journal: Diabetologia
Title: Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.
Volume: 48
Issue: 11
Pages: 2313-21
Publication
First Author: Luuk H
Year: 2009
Journal: Behav Brain Res
Title: Wfs1-deficient mice display impaired behavioural adaptation in stressful environment.
Volume: 198
Issue: 2
Pages: 334-45
Publication  
First Author: Visnapuu T
Year: 2013
Journal: Front Neurosci
Title: Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants.
Volume: 7
Pages: 132
Publication  
First Author: Noormets K
Year: 2009
Journal: Reprod Biol Endocrinol
Title: Male mice with deleted Wolframin (Wfs1) gene have reduced fertility.
Volume: 7
Pages: 82
Publication
First Author: Noormets K
Year: 2014
Journal: Exp Clin Endocrinol Diabetes
Title: Energy metabolism and thyroid function of mice with deleted wolframin (Wfs1) gene.
Volume: 122
Issue: 5
Pages: 281-6
Publication
First Author: Kondo M
Year: 2018
Journal: Diabetologia
Title: Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.
Volume: 61
Issue: 10
Pages: 2189-2201
Publication
First Author: Ishigaki S
Year: 2010
Journal: Cell Death Differ
Title: AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Volume: 17
Issue: 5
Pages: 774-86
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Fernandez-Marcos PJ
Year: 2010
Journal: PLoS One
Title: Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1.
Volume: 5
Issue: 1
Pages: e8744
Publication  
First Author: Altpere A
Year: 2018
Journal: Behav Brain Res
Title: Mild stress induces brain region-specific alterations of selective ER stress markers' mRNA expression in Wfs1-deficient mice.
Volume: 352
Pages: 94-98
Publication
First Author: Noormets K
Year: 2011
Journal: Exp Clin Endocrinol Diabetes
Title: Sex differences in the development of diabetes in mice with deleted wolframin (Wfs1) gene.
Volume: 119
Issue: 5
Pages: 271-5
GXD Expression      
Probe: MGI:5292098
Assay Type: RT-PCR
Annotation Date: 2011-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Stage: TS24
Assay Id: MGI:5293477
Age: embryonic day 16.5
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 0
Specimen Label: 1M
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 2
Specimen Label: 2A
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 2
Specimen Label: 2B
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 2
Specimen Label: 2C
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5704217
Age: postnatal day 4
Specimen Label: 2E
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Diffuse
Stage: TS26
Assay Id: MGI:5704217
Age: embryonic day 18.5
Specimen Label: 4A
Detected: true
Specimen Num: 29
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Diffuse
Stage: TS26
Assay Id: MGI:5704217
Age: embryonic day 18.5
Specimen Label: 1I
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Diffuse
Stage: TS26
Assay Id: MGI:5704217
Age: embryonic day 18.5
Specimen Label: 1J
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Diffuse
Stage: TS26
Assay Id: MGI:5704217
Age: embryonic day 18.5
Specimen Label: 1K
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Diffuse
Stage: TS26
Assay Id: MGI:5704217
Age: embryonic day 18.5
Specimen Label: 1L
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5704217
Age: postnatal day 20
Specimen Label: 2K
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 0
Specimen Label: not shown P0
Detected: true
Specimen Num: 43
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3529727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 0
Specimen Label: Table2a P0
Detected: true
Specimen Num: 47
GXD Expression    
Probe: MGI:5704201
Assay Type: RNA in situ
Annotation Date: 2016-01-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3529727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5704217
Age: postnatal day 2
Specimen Label: Table2a P2
Detected: true
Specimen Num: 48