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Search results 1 to 85 out of 85 for Wnk3

0.049s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lee AY
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.
Volume: 109
Issue: 42
Pages: 16841-6
Publication
First Author: Oi K
Year: 2012
Journal: Biol Open
Title: A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo.
Volume: 1
Issue: 2
Pages: 120-7
Publication
First Author: Begum G
Year: 2015
Journal: Stroke
Title: Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke.
Volume: 46
Issue: 7
Pages: 1956-1965
Publication
First Author: Mederle K
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Loss of WNK3 is compensated for by the WNK1/SPAK axis in the kidney of the mouse.
Volume: 304
Issue: 9
Pages: F1198-209
Publication  
First Author: Lim WM
Year: 2021
Journal: Front Mol Neurosci
Title: WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons.
Volume: 14
Pages: 762142
Publication
First Author: Rinehart J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.
Volume: 102
Issue: 46
Pages: 16777-82
Publication
First Author: Yang D
Year: 2011
Journal: J Clin Invest
Title: IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.
Volume: 121
Issue: 3
Pages: 956-65
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Zhao H
Year: 2017
Journal: J Cereb Blood Flow Metab
Title: Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke.
Volume: 37
Issue: 2
Pages: 550-563
Publication  
First Author: Zhang J
Year: 2016
Journal: Sci Rep
Title: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Volume: 6
Pages: 35986
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:4423875
Assay Type: RNA in situ
Annotation Date: 2021-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647022
Stage: TS22
Assay Id: MGI:6781621
Age: embryonic day 14.5
Specimen Label: S5C
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6186851
Assay Type: RNA in situ
Annotation Date: 2021-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6781625
Age: postnatal adult
Specimen Label: S5G,G'
Detected: false
Specimen Num: 1
Publication
First Author: Izadifar A
Year: 2021
Journal: Neuron
Title: Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.
Volume: 109
Issue: 18
Pages: 2864-2883.e8
Publication      
First Author: Cox BJ
Year: 2010
Journal: MGI Direct Data Submission
Title: Phenotypic annotation of the mouse X chromosome
Publication
First Author: Cox BJ
Year: 2010
Journal: Genome Res
Title: Phenotypic annotation of the mouse X chromosome.
Volume: 20
Issue: 8
Pages: 1154-64
Publication      
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Glover M
Year: 2009
Journal: J Am Soc Nephrol
Title: Renal and brain isoforms of WNK3 have opposite effects on NCCT expression.
Volume: 20
Issue: 6
Pages: 1314-22
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase WNK3
Type: chain
End: 1757
Publication
First Author: Lagnaz D
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter.
Volume: 307
Issue: 3
Pages: F275-86
Protein
Organism: Mus musculus/domesticus
Length: 1757  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1710  
Fragment?: false
Interaction Experiment
Description: WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter.
Allele
Name: WNK lysine deficient protein kinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Ponce-Coria J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.
Volume: 105
Issue: 24
Pages: 8458-63
Publication
First Author: Chávez-Canales M
Year: 2014
Journal: Hypertension
Title: WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Volume: 64
Issue: 5
Pages: 1047-53
Publication
First Author: Yang CL
Year: 2007
Journal: J Clin Invest
Title: The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
Volume: 117
Issue: 11
Pages: 3403-11
Publication
First Author: Dorwart MR
Year: 2007
Journal: J Physiol
Title: SLC26A9 is a Cl(-) channel regulated by the WNK kinases.
Volume: 584
Issue: Pt 1
Pages: 333-45
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112