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Search results 1 to 91 out of 91 for Wnk3

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
65267 | WNK3
Type: gene
Organism: human
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Gene
448601 | wnk3
Type: gene
Organism: frog, western clawed
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Gene
465653 | WNK3
Type: gene
Organism: chimpanzee
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Gene
317420 | Wnk3
Type: gene
Organism: rat
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Gene
491900 | WNK3
Type: gene
Organism: dog, domestic
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Gene
100337119 | WNK3
Type: gene
Organism: cattle
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Gene
567408 | wnk3
Type: gene
Organism: zebrafish
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Gene
701015 | WNK3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2652875 | Wnk3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23027929 | J:190304
First Author: Lee AY
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.
Volume: 109
Issue: 42
Pages: 16841-6
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Publication
23213404 | J:181538
First Author: Oi K
Year: 2012
Journal: Biol Open
Title: A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo.
Volume: 1
Issue: 2
Pages: 120-7
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Publication
26069258 | J:264925
First Author: Begum G
Year: 2015
Journal: Stroke
Title: Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke.
Volume: 46
Issue: 7
Pages: 1956-1965
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Publication
23427142 | J:197267
First Author: Mederle K
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Loss of WNK3 is compensated for by the WNK1/SPAK axis in the kidney of the mouse.
Volume: 304
Issue: 9
Pages: F1198-209
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Publication
34858138 | J:315133
 
First Author: Lim WM
Year: 2021
Journal: Front Mol Neurosci
Title: WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons.
Volume: 14
Pages: 762142
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Publication
16275913 | J:172996
First Author: Rinehart J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.
Volume: 102
Issue: 46
Pages: 16777-82
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Gene
101883538 | LOC101883538
Type: gene
Organism: zebrafish
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Publication
21317537 | J:172037
First Author: Yang D
Year: 2011
Journal: J Clin Invest
Title: IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.
Volume: 121
Issue: 3
Pages: 956-65
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Publication
26861815 | J:264975
First Author: Zhao H
Year: 2017
Journal: J Cereb Blood Flow Metab
Title: Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke.
Volume: 37
Issue: 2
Pages: 550-563
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Publication
27782176 | J:278187
 
First Author: Zhang J
Year: 2016
Journal: Sci Rep
Title: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Volume: 6
Pages: 35986
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Protein Coding Gene
MGP_CAROLIEiJ_G0033492 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0036152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036143 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2652875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035142 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0036077 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036703 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0032031 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034662 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:4423875
Assay Type: RNA in situ
Annotation Date: 2021-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647022
Stage: TS22
Assay Id: MGI:6781621
Age: embryonic day 14.5
Specimen Label: S5C
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6186851
Assay Type: RNA in situ
Annotation Date: 2021-10-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6781625
Age: postnatal adult
Specimen Label: S5G,G'
Detected: false
Specimen Num: 1
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Publication
34384519 | J:310867
First Author: Izadifar A
Year: 2021
Journal: Neuron
Title: Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.
Volume: 109
Issue: 18
Pages: 2864-2883.e8
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Publication
20548051 | J:163340
First Author: Cox BJ
Year: 2010
Journal: Genome Res
Title: Phenotypic annotation of the mouse X chromosome.
Volume: 20
Issue: 8
Pages: 1154-64
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Publication
- | J:160967
     
First Author: Cox BJ
Year: 2010
Journal: MGI Direct Data Submission
Title: Phenotypic annotation of the mouse X chromosome
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Publication
- | J:200814
     
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19470686 | -
First Author: Glover M
Year: 2009
Journal: J Am Soc Nephrol
Title: Renal and brain isoforms of WNK3 have opposite effects on NCCT expression.
Volume: 20
Issue: 6
Pages: 1314-22
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase WNK3
Type: chain
End: 1757
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Publication
24920754 | J:212100
First Author: Lagnaz D
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter.
Volume: 307
Issue: 3
Pages: F275-86
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Protein
Q80XP9
Organism: Mus musculus/domesticus
Length: 1757  
Fragment?: false
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Protein
Q80XP9-2
Organism: Mus musculus/domesticus
Length: 1710  
Fragment?: false
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Interaction Experiment
Lagnaz D (2014)
Description: WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter.
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Allele
Wnk3<em1Smoc> | MGI:7293177
Name: WNK lysine deficient protein kinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
18550832 | -
First Author: Ponce-Coria J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.
Volume: 105
Issue: 24
Pages: 8458-63
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DO Term
DOID:0060805 | Prieto syndrome
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Publication
25113964 | J:284008
First Author: Chávez-Canales M
Year: 2014
Journal: Hypertension
Title: WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Volume: 64
Issue: 5
Pages: 1047-53
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Publication
17975670 | J:127376
First Author: Yang CL
Year: 2007
Journal: J Clin Invest
Title: The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
Volume: 117
Issue: 11
Pages: 3403-11
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Publication
17673510 | J:336068
First Author: Dorwart MR
Year: 2007
Journal: J Physiol
Title: SLC26A9 is a Cl(-) channel regulated by the WNK kinases.
Volume: 584
Issue: Pt 1
Pages: 333-45
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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