Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
Not Specified |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Wnt proteins constitute a large family of secreted molecules that are involved in intercellular signalling during development. The name derives from the first 2 members of the family to be discovered: int-1 (mouse) and wingless (Drosophila) []. It is now recognised that Wnt signalling controls many cell fate decisions in a variety of different organisms, including mammals []. Wnt signalling has been implicated in tumourigenesis, early mesodermal patterning of the embryo, morphogenesis of the brain and kidneys, regulation of mammary gland proliferation and Alzheimer's disease [, ].Wnt-mediated signalling is believed to proceed initially through binding to cell surface receptors of the frizzled family; the signal is subsequently transduced through several cytoplasmic components to B-catenin, which enters the nucleus and activates the transcription of several genes important indevelopment []. Several non-canonical Wnt signalling pathways have also been elucidated that act independently of B-catenin. Canonical and noncanonical Wnt signaling branches are highly interconnected, and cross-regulate each other [].Members of the Wnt gene family are defined by their sequence similarity to mouse Wnt-1 and Wingless in Drosophila. They encode proteins of ~350-400 residues in length, with orthologues identified in several, mostly vertebrate, species. Very little is known about the structure of Wnts as they are notoriously insoluble, but they share the following features characteristics of secretory proteins: a signal peptide, several potential N-glycosylation sites and 22 conserved cysteines []that are probably involved in disulphide bonds. The Wnt proteins seem to adhere to the plasma membrane of the secreting cells and are therefore likely to signal over only few cell diameters. Fifteen major Wnt gene families have been identified in vertebrates, with multiple subtypes within some classes.Wnt5a is required for prostate gland development [], intestinal elongation []and endothelial differentiation of embryonic stem cells []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Cervantes S |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
Wnt5a is essential for intestinal elongation in mice. |
Volume: |
326 |
Issue: |
2 |
Pages: |
285-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang DH |
Year: |
2009 |
Journal: |
Circ Res |
Title: |
Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha. |
Volume: |
104 |
Issue: |
3 |
Pages: |
372-9 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702321 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:7520447 |
Age: |
embryonic day 13.5 |
Image: |
4B Wnt5a |
Note: |
Low levels of expression in a subset of epithelial cells. |
Specimen Label: |
4B Wnt5a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6492177 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3594417 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6492180 |
Age: |
embryonic day 10.5 |
Image: |
3A Wnt5a |
Note: |
Authors report co-expression with Hoxa13 in distal limb bud. |
Specimen Label: |
3A Wnt5a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3510436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:3510682 |
Age: |
embryonic day 10.5 |
Image: |
Wnt5a Ednra+/+ |
Note: |
Expression is in the proximal portion of the mandibular arch. |
Specimen Label: |
Wnt5a Ednra+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702221 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7520447 |
Age: |
embryonic day 13.5 |
Image: |
4B Wnt5a |
|
Specimen Label: |
4B Wnt5a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3510436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1638217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:3510682 |
Age: |
embryonic day 10.5 |
Image: |
Wnt5a Ednra-/- |
Note: |
In this mutant, expression spreads into the distal half of the arch. |
Specimen Label: |
Wnt5a Ednra-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6406959 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689321 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6407065 |
Age: |
embryonic day 13.5 |
Image: |
3D Wnt5a |
Note: |
High levels of expression in mesenchyme of body wall. |
Specimen Label: |
3D Wnt5a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6492177 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-15 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640524 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6492180 |
Age: |
embryonic day 16.5 |
Image: |
3B Wnt5a NULL |
Note: |
Expression substantially reduced compared to wild type limb buds. |
Specimen Label: |
3B Wnt5a NULL |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 0 |
Image: |
5G Wnt5a P0 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
5G Wnt5a P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7520040 |
Age: |
embryonic day 18.0 |
Image: |
S8A Wnt5a E18 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a E18 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 5 |
Image: |
S8A Wnt5a P5 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a P5 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6492177 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3272824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6492180 |
Age: |
embryonic day 16.5 |
Image: |
3B Wnt5a WT |
|
Specimen Label: |
3B Wnt5a WT |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6406959 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-04-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276121 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6407065 |
Age: |
embryonic day 13.5 |
Image: |
3D Wnt5a inset |
Note: |
Authors state expression not prominent in epidermis of body wall. |
Specimen Label: |
3D Wnt5a inset |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:7520040 |
Age: |
embryonic day 15.0 |
Image: |
5G Wnt5a E15 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
5G Wnt5a E15 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672826 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7520040 |
Age: |
embryonic day 18.0 |
Image: |
5G Wnt5a E18 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
5G Wnt5a E18 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 3 |
Image: |
5G Wnt5a P3 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
5G Wnt5a P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:7520040 |
Age: |
embryonic day 15.0 |
Image: |
S8A Wnt5a E15 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a E15 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 0 |
Image: |
S8A Wnt5a P0 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a P0 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 3 |
Image: |
S8A Wnt5a P3 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a P3 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 7 |
Image: |
S8A Wnt5a P7 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a P7 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7519213 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7520040 |
Age: |
postnatal day 14 |
Image: |
S8A Wnt5a P14 |
Note: |
Expression in myofibroblasts. |
Specimen Label: |
S8A Wnt5a P14 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294254 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1844124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6294266 |
Age: |
embryonic day 16.5 |
Image: |
4A Wnt5a fl/fl |
|
Specimen Label: |
4A Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294254 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1775124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6294266 |
Age: |
embryonic day 16.5 |
Image: |
4B Wnt5a fl/fl |
|
Specimen Label: |
4B Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6492177 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3272724 |
Pattern: |
Scattered |
Stage: |
TS24 |
Assay Id: |
MGI:6492180 |
Age: |
embryonic day 16.5 |
Image: |
3B Wnt5a WT |
|
Specimen Label: |
3B Wnt5a WT |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3763819 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-03-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1741220 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:2450641 |
Age: |
embryonic day 12.5 |
Image: |
2B, Wnt5a -/- |
Note: |
Expression reduced to below detectable levels in long bone cartilage; normal expression in distal limb. |
Specimen Label: |
2B, Wnt5a -/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6492177 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-01-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6492180 |
Age: |
embryonic day 16.5 |
Image: |
3B Wnt5a WT |
|
Specimen Label: |
3B Wnt5a WT |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3513367 |
Assay Type: |
RT-PCR |
Annotation Date: |
2005-01-10 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:360453 |
|
Stage: |
TS03 |
Assay Id: |
MGI:3513385 |
Age: |
embryonic day 3.0 |
|
|
Specimen Label: |
Wnt5a |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3513367 |
Assay Type: |
RT-PCR |
Annotation Date: |
2005-01-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360465 |
|
Stage: |
TS05 |
Assay Id: |
MGI:3513403 |
Age: |
embryonic day 4.0 |
|
|
Specimen Label: |
Wnt5a |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5445428 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-12-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3639222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5445538 |
Age: |
embryonic day 14.5 |
Image: |
2 |
|
Specimen Label: |
Wnt5a |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang L |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
The role of Wnt5a in prostate gland development. |
Volume: |
328 |
Issue: |
2 |
Pages: |
188-99 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1355120 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-03-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1910623 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:2450652 |
Age: |
embryonic day 15.5 |
Image: |
8B, Wnt5a -/-, 15.5 dpc |
Note: |
Expression increased in Wnt5a -/- mutant. |
Specimen Label: |
8B, Wnt5a -/-, 15.5 dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2450421 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2003-03-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1910623 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:2450658 |
Age: |
embryonic day 15.5 |
Image: |
8A, Wnt5a -/-, 15.5 dpc |
Note: |
Protein level decreased in Wnt5a -/- mutant. |
Specimen Label: |
8A, Wnt5a -/-, 15.5 dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wodarz A |
Year: |
1998 |
Journal: |
Annu Rev Cell Dev Biol |
Title: |
Mechanisms of Wnt signaling in development. |
Volume: |
14 |
|
Pages: |
59-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Ferrari GV |
Year: |
2000 |
Journal: |
Brain Res Brain Res Rev |
Title: |
Wnt signaling function in Alzheimer's disease. |
Volume: |
33 |
Issue: |
1 |
Pages: |
1-12 |
|
•
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•
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Publication |
First Author: |
Peifer M |
Year: |
2000 |
Journal: |
Science |
Title: |
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. |
Volume: |
287 |
Issue: |
5458 |
Pages: |
1606-9 |
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•
•
•
•
•
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Publication |
First Author: |
Semënov MV |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Human dishevelled genes constitute a DHR-containing multigene family. |
Volume: |
42 |
Issue: |
2 |
Pages: |
302-10 |
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•
•
•
•
•
|
Publication |
First Author: |
Bejsovec A |
Year: |
1999 |
Journal: |
Curr Biol |
Title: |
Wnt signalling shows its versatility. |
Volume: |
9 |
Issue: |
18 |
Pages: |
R684-7 |
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•
•
•
•
•
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Publication |
First Author: |
Kestler HA |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
Generating a Wnt switch: it's all about the right dosage. |
Volume: |
193 |
Issue: |
3 |
Pages: |
431-3 |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
380
 |
Fragment?: |
false |
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•
•
•
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Publication |
First Author: |
GarcÃa GarcÃa CJ |
Year: |
2021 |
Journal: |
Front Oncol |
Title: |
HIF2 Regulates Intestinal Wnt5a Expression. |
Volume: |
11 |
|
Pages: |
769385 |
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•
•
•
•
•
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Publication |
First Author: |
Nishizuka M |
Year: |
2008 |
Journal: |
FEBS Lett |
Title: |
Wnt4 and Wnt5a promote adipocyte differentiation. |
Volume: |
582 |
Issue: |
21-22 |
Pages: |
3201-5 |
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•
•
•
•
•
|
Publication |
First Author: |
Allgeier SH |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
WNT5A selectively inhibits mouse ventral prostate development. |
Volume: |
324 |
Issue: |
1 |
Pages: |
10-7 |
|
•
•
•
•
•
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Publication |
First Author: |
Okamoto M |
Year: |
2014 |
Journal: |
Sci Rep |
Title: |
Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis. |
Volume: |
4 |
|
Pages: |
4493 |
|
•
•
•
•
•
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Publication |
First Author: |
Cha KB |
Year: |
2004 |
Journal: |
Mech Dev |
Title: |
WNT5A signaling affects pituitary gland shape. |
Volume: |
121 |
Issue: |
2 |
Pages: |
183-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li C |
Year: |
2002 |
Journal: |
Dev Biol |
Title: |
Wnt5a participates in distal lung morphogenesis. |
Volume: |
248 |
Issue: |
1 |
Pages: |
68-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishihara H |
Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate. |
Volume: |
12 |
Issue: |
10 |
Pages: |
e1006380 |
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•
•
•
•
•
|
Publication |
First Author: |
Borcherding N |
Year: |
2015 |
Journal: |
Cancer Res |
Title: |
Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells. |
Volume: |
75 |
Issue: |
10 |
Pages: |
1972-82 |
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•
•
•
•
•
|
Publication |
First Author: |
Maity S |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Wnt5A Signaling Blocks Progression of Experimental Visceral Leishmaniasis. |
Volume: |
13 |
|
Pages: |
818266 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pino D |
Year: |
2011 |
Journal: |
ASN Neuro |
Title: |
Wnt5a controls neurite development in olfactory bulb interneurons. |
Volume: |
3 |
Issue: |
3 |
Pages: |
e00059 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2013 |
Journal: |
Int J Med Sci |
Title: |
Wnt5a inhibits the proliferation and melanogenesis of melanocytes. |
Volume: |
10 |
Issue: |
6 |
Pages: |
699-706 |
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•
•
•
•
•
|
Publication |
First Author: |
Blakely BD |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Wnt5a regulates midbrain dopaminergic axon growth and guidance. |
Volume: |
6 |
Issue: |
3 |
Pages: |
e18373 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li B |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
WNT5A signaling contributes to Aβ-induced neuroinflammation and neurotoxicity. |
Volume: |
6 |
Issue: |
8 |
Pages: |
e22920 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee GJ |
Year: |
2022 |
Journal: |
Cell Death Dis |
Title: |
YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity. |
Volume: |
13 |
Issue: |
4 |
Pages: |
407 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tai CC |
Year: |
2009 |
Journal: |
J Surg Res |
Title: |
Wnt5a knock-out mouse as a new model of anorectal malformation. |
Volume: |
156 |
Issue: |
2 |
Pages: |
278-82 |
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•
•
•
•
•
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Publication |
First Author: |
Schaap-Oziemlak AM |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Wnt5a does not support hematopoiesis in stroma-free, serum-free cultures. |
Volume: |
8 |
Issue: |
1 |
Pages: |
e53669 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chakraborty A |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
Wnt5a Signaling Promotes Host Defense against Leishmania donovani Infection. |
Volume: |
199 |
Issue: |
3 |
Pages: |
992-1002 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koopmans T |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation. |
Volume: |
10 |
Issue: |
1 |
Pages: |
6754 |
|
•
•
•
•
•
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Publication |
First Author: |
Sarraf TR |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Wnt5A signaling supports antigen processing and CD8 T cell activation. |
Volume: |
13 |
|
Pages: |
960060 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ando F |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway. |
Volume: |
7 |
|
Pages: |
13636 |
|
•
•
•
•
•
|
Publication |
First Author: |
Buckley SM |
Year: |
2011 |
Journal: |
Exp Hematol |
Title: |
Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line. |
Volume: |
39 |
Issue: |
1 |
Pages: |
114-123.e1-5 |
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•
•
•
•
•
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Publication |
First Author: |
Andre P |
Year: |
2015 |
Journal: |
Development |
Title: |
Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. |
Volume: |
142 |
Issue: |
8 |
Pages: |
1516-27 |
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•
•
•
•
•
|
Publication |
First Author: |
Asem M |
Year: |
2020 |
Journal: |
Cancer Res |
Title: |
Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis. |
Volume: |
80 |
Issue: |
5 |
Pages: |
1156-1170 |
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•
•
•
•
•
|
Publication |
First Author: |
Mericskay M |
Year: |
2004 |
Journal: |
Development |
Title: |
Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus. |
Volume: |
131 |
Issue: |
9 |
Pages: |
2061-72 |
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•
•
•
•
•
|
Publication |
First Author: |
Kawarazaki W |
Year: |
2020 |
Journal: |
J Clin Invest |
Title: |
Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency. |
Volume: |
130 |
Issue: |
8 |
Pages: |
4152-4166 |
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•
•
•
•
•
|
Publication |
First Author: |
Andersson ER |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
Genetic interaction between Lrp6 and Wnt5a during mouse development. |
Volume: |
239 |
Issue: |
1 |
Pages: |
237-45 |
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•
•
•
•
•
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Publication |
First Author: |
Sato A |
Year: |
2010 |
Journal: |
EMBO J |
Title: |
Wnt5a regulates distinct signalling pathways by binding to Frizzled2. |
Volume: |
29 |
Issue: |
1 |
Pages: |
41-54 |
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•
•
•
•
•
|
Publication |
First Author: |
Qian D |
Year: |
2007 |
Journal: |
Dev Biol |
Title: |
Wnt5a functions in planar cell polarity regulation in mice. |
Volume: |
306 |
Issue: |
1 |
Pages: |
121-33 |
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•
•
•
•
•
|
Publication |
First Author: |
Schleiffarth JR |
Year: |
2007 |
Journal: |
Pediatr Res |
Title: |
Wnt5a is required for cardiac outflow tract septation in mice. |
Volume: |
61 |
Issue: |
4 |
Pages: |
386-91 |
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•
•
•
•
•
|
Publication |
First Author: |
Mikels A |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. |
Volume: |
284 |
Issue: |
44 |
Pages: |
30167-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alcantara MC |
Year: |
2021 |
Journal: |
Congenit Anom (Kyoto) |
Title: |
Stage-dependent function of Wnt5a during male external genitalia development. |
Volume: |
61 |
Issue: |
6 |
Pages: |
212-219 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li C |
Year: |
2005 |
Journal: |
Dev Biol |
Title: |
Wnt5a regulates Shh and Fgf10 signaling during lung development. |
Volume: |
287 |
Issue: |
1 |
Pages: |
86-97 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294256 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1715727 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6294273 |
Age: |
postnatal day 0.5 |
Image: |
4 |
|
Specimen Label: |
SCG Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294256 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1775127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6294273 |
Age: |
postnatal day 0.5 |
Image: |
4 |
|
Specimen Label: |
Salivary glands Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294256 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1844127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6294274 |
Age: |
postnatal day 0.5 |
Image: |
S1 |
|
Specimen Label: |
SCG Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294256 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610527 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6294274 |
Age: |
postnatal day 0.5 |
Image: |
S1 |
|
Specimen Label: |
Heart Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294256 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1775127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6294274 |
Age: |
postnatal day 0.5 |
Image: |
S1 |
|
Specimen Label: |
Salivary glands Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6294257 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-04-24 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1844127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6294275 |
Age: |
postnatal day 0.5 |
Image: |
S2 |
|
Specimen Label: |
RT+ Wnt5a fl/fl |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3041687 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-06-03 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1667215 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:3042032 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Table 1, Wnt5a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Amerongen R |
Year: |
2012 |
Journal: |
Dev Biol |
Title: |
Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development. |
Volume: |
369 |
Issue: |
1 |
Pages: |
101-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christman MA 2nd |
Year: |
2008 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Wnt5a is expressed in murine and human atherosclerotic lesions. |
Volume: |
294 |
Issue: |
6 |
Pages: |
H2864-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Easter SL |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors. |
Volume: |
9 |
Issue: |
11 |
Pages: |
e113247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clark CE |
Year: |
2014 |
Journal: |
Growth Factors |
Title: |
Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth. |
Volume: |
32 |
Issue: |
1 |
Pages: |
11-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang L |
Year: |
2014 |
Journal: |
Nephron Exp Nephrol |
Title: |
Wnt5a is necessary for normal kidney development in zebrafish and mice. |
Volume: |
128 |
Issue: |
1-2 |
Pages: |
80-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ghosh MC |
Year: |
2009 |
Journal: |
Blood |
Title: |
Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration. |
Volume: |
114 |
Issue: |
7 |
Pages: |
1366-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abedini A |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Non-canonical WNT5a regulates Epithelial-to-Mesenchymal Transition in the mouse ovarian surface epithelium. |
Volume: |
10 |
Issue: |
1 |
Pages: |
9695 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang H |
Year: |
2003 |
Journal: |
Cancer Cell |
Title: |
Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue. |
Volume: |
4 |
Issue: |
5 |
Pages: |
349-60 |
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•
•
•
•
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