Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Wnt proteins constitute a large family of secreted molecules that are involved in intercellular signalling during development. The name derives from the first 2 members of the family to be discovered: int-1 (mouse) and wingless (Drosophila) []. It is now recognised that Wnt signalling controls many cell fate decisions in a variety of different organisms, including mammals []. Wnt signalling has been implicated in tumourigenesis, early mesodermal patterning of the embryo, morphogenesis of the brain and kidneys, regulation of mammary gland proliferation and Alzheimer's disease [, ].Wnt-mediated signalling is believed to proceed initially through binding to cell surface receptors of the frizzled family; the signal is subsequently transduced through several cytoplasmic components to B-catenin, which enters the nucleus and activates the transcription of several genes important indevelopment []. Several non-canonical Wnt signalling pathways have also been elucidated that act independently of B-catenin. Canonical and noncanonical Wnt signaling branches are highly interconnected, and cross-regulate each other [].Members of the Wnt gene family are defined by their sequence similarity to mouse Wnt-1 and Wingless in Drosophila. They encode proteins of ~350-400 residues in length, with orthologues identified in several, mostly vertebrate, species. Very little is known about the structure of Wnts as they are notoriously insoluble, but they share the following features characteristics of secretory proteins: a signal peptide, several potential N-glycosylation sites and 22 conserved cysteines []that are probably involved in disulphide bonds. The Wnt proteins seem to adhere to the plasma membrane of the secreting cells and are therefore likely to signal over only few cell diameters. Fifteen major Wnt gene families have been identified in vertebrates, with multiple subtypes within some classes.Human Wnt-9a (previously Wnt-14) maps to chromosome 1 and originates, together with Wnt-9b (previously Wnt-15), from an ancestral branch of the Wnt gene family, which includes the Wnt-9 sequences found in jawless and cartilaginous fishes []. Wnt-9a (Wnt14) mRNA is expressed in various types of human cancer, such as gastric and pancreatic cancer []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271224 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271820 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the premam zone and the TT. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690819 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 11.5 |
Image: |
Wnt9a - E11.5 |
Note: |
There is strong staining in the VZ of the mam zone. Staining is either absent or ubiquitous in the VZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs, the PVH, VMH & ARH nuclei, the AVH, anterior & posterior IDs, premam & supramam zones & TT. |
Specimen Label: |
Wnt9a - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753922 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753924 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
There is strong staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Wnt9a - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271020 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the premam zone and the TT. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271024 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
There is weak staining in the ventricular zone of the mam zone. Staining is either absent or ubiquitous in the ventricular zone of the premam and supramam zones. |
Specimen Label: |
Wnt9a - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266520 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266524 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 11.5 |
Image: |
Wnt9a - E11.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT. |
Specimen Label: |
Wnt9a - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 16.5 |
Image: |
Wnt9a - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Wnt9a - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271220 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754320 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691319 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 11.5 |
Image: |
Wnt9a - E11.5 |
Note: |
There is strong staining in the ventricular zone of the cerebral cortex. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences. |
Specimen Label: |
Wnt9a - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Wnt9a - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753920 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691119 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 11.5 |
Image: |
Wnt9a - E11.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Wnt9a - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
There is strong staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Wnt9a - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271022 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 14.5 |
Image: |
Wnt9a - E14.5 |
Note: |
There is moderate staining in the ventricular zone of the mam zone. Staining is either absent or ubiquitous in the ventricular zone of the premam and supramam zones and the TT. |
Specimen Label: |
Wnt9a - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3194930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450839 |
Age: |
embryonic day 12.5 |
Image: |
Wnt9a - E12.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Wnt9a - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Später D |
Year: |
2006 |
Journal: |
Development |
Title: |
Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. |
Volume: |
133 |
Issue: |
15 |
Pages: |
3039-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo C |
Year: |
2018 |
Journal: |
J Am Soc Nephrol |
Title: |
Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells. |
Volume: |
29 |
Issue: |
4 |
Pages: |
1238-1256 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pujadas G |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas. |
Volume: |
6 |
|
Pages: |
19223 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weissenböck M |
Year: |
2019 |
Journal: |
Genes Cells |
Title: |
Genetic interactions between Ror2 and Wnt9a, Ror1 and Wnt9a and Ror2 and Ror1: Phenotypic analysis of the limb skeleton and palate in compound mutants. |
Volume: |
24 |
Issue: |
4 |
Pages: |
307-317 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bergstein I |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. |
Volume: |
46 |
Issue: |
3 |
Pages: |
450-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
365
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
365
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
361
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wodarz A |
Year: |
1998 |
Journal: |
Annu Rev Cell Dev Biol |
Title: |
Mechanisms of Wnt signaling in development. |
Volume: |
14 |
|
Pages: |
59-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Ferrari GV |
Year: |
2000 |
Journal: |
Brain Res Brain Res Rev |
Title: |
Wnt signaling function in Alzheimer's disease. |
Volume: |
33 |
Issue: |
1 |
Pages: |
1-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peifer M |
Year: |
2000 |
Journal: |
Science |
Title: |
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. |
Volume: |
287 |
Issue: |
5458 |
Pages: |
1606-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Semënov MV |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Human dishevelled genes constitute a DHR-containing multigene family. |
Volume: |
42 |
Issue: |
2 |
Pages: |
302-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bejsovec A |
Year: |
1999 |
Journal: |
Curr Biol |
Title: |
Wnt signalling shows its versatility. |
Volume: |
9 |
Issue: |
18 |
Pages: |
R684-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kestler HA |
Year: |
2011 |
Journal: |
J Cell Biol |
Title: |
Generating a Wnt switch: it's all about the right dosage. |
Volume: |
193 |
Issue: |
3 |
Pages: |
431-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kirikoshi H |
Year: |
2001 |
Journal: |
Int J Oncol |
Title: |
Expression of WNT14 and WNT14B mRNAs in human cancer, up-regulation of WNT14 by IFNgamma and up-regulation of WNT14B by beta-estradiol. |
Volume: |
19 |
Issue: |
6 |
Pages: |
1221-5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6191576 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Wnt9a |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191576 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Wnt9a |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191576 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Wnt9a |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6191576 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Wnt9a |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6191576 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Wnt9a |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191576 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Wnt9a |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6186889 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191576 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Wnt9a |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bartoletti G |
Year: |
2020 |
Journal: |
Dev Biol |
Title: |
Pdgfra regulates multipotent cell differentiation towards chondrocytes via inhibiting Wnt9a/beta-catenin pathway during chondrocranial cartilage development. |
Volume: |
466 |
Issue: |
1-2 |
Pages: |
36-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dy P |
Year: |
2010 |
Journal: |
Dev Biol |
Title: |
Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. |
Volume: |
341 |
Issue: |
2 |
Pages: |
346-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qian J |
Year: |
2003 |
Journal: |
Genomics |
Title: |
Mouse Wnt9b transforming activity, tissue-specific expression, and evolution. |
Volume: |
81 |
Issue: |
1 |
Pages: |
34-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kemp C |
Year: |
2005 |
Journal: |
Dev Dyn |
Title: |
Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development. |
Volume: |
233 |
Issue: |
3 |
Pages: |
1064-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kan A |
Year: |
2013 |
Journal: |
Genes Dev |
Title: |
c-Jun is required for the specification of joint cell fates. |
Volume: |
27 |
Issue: |
5 |
Pages: |
514-24 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Heart |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Brain |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Spleen |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Lung |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Liver |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Skeletal muscle |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Kidney |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2447465 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Testis |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2447462 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-01-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603910 |
|
Stage: |
TS10 |
Assay Id: |
MGI:2447465 |
Age: |
embryonic day 7.0 |
|
|
Specimen Label: |
7-day embryo |
Detected: |
false |
Specimen Num: |
10 |
|
•
•
•
•
•
|