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Search results 1 to 100 out of 149 for Wrn

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Huang S
Year: 2000
Journal: Nucleic Acids Res
Title: Characterization of the human and mouse WRN 3'-->5' exonuclease.
Volume: 28
Issue: 12
Pages: 2396-405
Publication
First Author: Moser R
Year: 2012
Journal: Mol Cancer Res
Title: MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency.
Volume: 10
Issue: 4
Pages: 535-45
Publication
First Author: Lombard DB
Year: 2000
Journal: Mol Cell Biol
Title: Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
Volume: 20
Issue: 9
Pages: 3286-91
Publication
First Author: Aumailley L
Year: 2015
Journal: PLoS One
Title: Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Volume: 10
Issue: 10
Pages: e0140292
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Xue Y
Year: 2002
Journal: Biochemistry
Title: A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'- 5' exonuclease and 5'-protruding strand endonuclease activities.
Volume: 41
Issue: 9
Pages: 2901-12
Publication
First Author: Aumailley L
Year: 2018
Journal: FASEB J
Title: Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
Volume: 32
Issue: 7
Pages: 3623-3640
Protein
Organism: Mus musculus
Length: 643  
Fragment?: false
Gene
Type: gene
Organism: Drosophila melanogaster
Publication
First Author: Laud PR
Year: 2005
Journal: Genes Dev
Title: Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.
Volume: 19
Issue: 21
Pages: 2560-70
Publication
First Author: Shen JC
Year: 2000
Journal: Trends Genet
Title: The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.
Volume: 16
Issue: 5
Pages: 213-20
Publication
First Author: Chang S
Year: 2005
Journal: Int J Biochem Cell Biol
Title: A mouse model of Werner Syndrome: what can it tell us about aging and cancer?
Volume: 37
Issue: 5
Pages: 991-9
Publication
First Author: Massip L
Year: 2006
Journal: Exp Gerontol
Title: Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue.
Volume: 41
Issue: 2
Pages: 157-68
Publication
First Author: Kahyo T
Year: 2008
Journal: FEBS Lett
Title: Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein.
Volume: 582
Issue: 17
Pages: 2479-83
Publication
First Author: Chang S
Year: 2004
Journal: Nat Genet
Title: Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Volume: 36
Issue: 8
Pages: 877-82
Publication
First Author: Aumailley L
Year: 2018
Journal: PLoS One
Title: Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
Volume: 13
Issue: 3
Pages: e0193170
Publication
First Author: Wu J
Year: 1998
Journal: Mech Ageing Dev
Title: Effect of age and apoptosis on the mouse homologue of the huWRN gene.
Volume: 103
Issue: 1
Pages: 27-44
Publication
First Author: Kawabe Yi
Year: 2001
Journal: J Biol Chem
Title: A novel protein interacts with the Werner's syndrome gene product physically and functionally.
Volume: 276
Issue: 23
Pages: 20364-9
Publication
First Author: Lebel M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity.
Volume: 95
Issue: 22
Pages: 13097-102
Publication
First Author: Kawabe Y
Year: 2000
Journal: J Biol Chem
Title: Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1.
Volume: 275
Issue: 28
Pages: 20963-6
Publication
First Author: Kanagaraj R
Year: 2012
Journal: Nucleic Acids Res
Title: Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage.
Volume: 40
Issue: 17
Pages: 8449-59
Publication
First Author: Du X
Year: 2004
Journal: Mol Cell Biol
Title: Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
Volume: 24
Issue: 19
Pages: 8437-46
Publication
First Author: Pignolo RJ
Year: 2008
Journal: Aging Cell
Title: Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis.
Volume: 7
Issue: 1
Pages: 23-31
Publication
First Author: DeschĂȘnes F
Year: 2005
Journal: Hum Mol Genet
Title: In vivo misregulation of genes involved in apoptosis, development and oxidative stress in mice lacking both functional Werner syndrome protein and poly(ADP-ribose) polymerase-1.
Volume: 14
Issue: 21
Pages: 3293-308
Publication
First Author: Lebel M
Year: 2003
Journal: Am J Pathol
Title: Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.
Volume: 162
Issue: 5
Pages: 1559-69
Publication
First Author: Leder A
Year: 2002
Journal: Oncogene
Title: Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis.
Volume: 21
Issue: 43
Pages: 6657-68
Publication
First Author: Suzuki T
Year: 2001
Journal: Oncogene
Title: Diverged nuclear localization of Werner helicase in human and mouse cells.
Volume: 20
Issue: 20
Pages: 2551-8
Publication
First Author: Cheng WH
Year: 2003
Journal: Mol Cell Biol
Title: Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution.
Volume: 23
Issue: 18
Pages: 6385-95
Publication
First Author: Bachrati CZ
Year: 2003
Journal: Biochem J
Title: RecQ helicases: suppressors of tumorigenesis and premature aging.
Volume: 374
Issue: Pt 3
Pages: 577-606
Publication
First Author: Lebel M
Year: 2002
Journal: Carcinogenesis
Title: Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue.
Volume: 23
Issue: 1
Pages: 213-6
Publication
First Author: Lebel M
Year: 2001
Journal: Cancer Res
Title: Tumorigenic effect of nonfunctional p53 or p21 in mice mutant in the Werner syndrome helicase.
Volume: 61
Issue: 5
Pages: 1816-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Imamura O
Year: 1997
Journal: Genomics
Title: Cloning of a mouse homologue of the human Werner syndrome gene and assignment to 8A4 by fluorescence in situ hybridization.
Volume: 41
Issue: 2
Pages: 298-300
Publication
First Author: Brennan TA
Year: 2014
Journal: Dis Model Mech
Title: Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.
Volume: 7
Issue: 5
Pages: 583-92
Publication  
First Author: Rekik K
Year: 2017
Journal: Behav Brain Res
Title: Cognitive deficit in hippocampal-dependent tasks in Werner syndrome mouse model.
Volume: 323
Pages: 68-77
Publication
First Author: Oshima J
Year: 2000
Journal: In Vivo
Title: Comparative aspects of the Werner syndrome gene.
Volume: 14
Issue: 1
Pages: 165-72
Publication
First Author: Yu CE
Year: 1996
Journal: Science
Title: Positional cloning of the Werner's syndrome gene.
Volume: 272
Issue: 5259
Pages: 258-62
GXD Expression    
Probe: MGI:2675700
Assay Type: RT-PCR
Annotation Date: 2003-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2675713
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2675700
Assay Type: RT-PCR
Annotation Date: 2003-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2675713
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2675700
Assay Type: RT-PCR
Annotation Date: 2003-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2675713
Age: postnatal
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2675702
Assay Type: Northern blot
Annotation Date: 2003-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2675709
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2675702
Assay Type: Northern blot
Annotation Date: 2003-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2675709
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2675702
Assay Type: Northern blot
Annotation Date: 2003-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2675709
Age: postnatal
Image: 2
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3526321
Assay Type: RNA in situ
Annotation Date: 2005-02-14
Strength: Present
Sex: Male
Emaps: EMAPS:1797321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3526379
Age: embryonic day 12.5
Note: Authors report epithelial expression.
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3526321
Assay Type: RNA in situ
Annotation Date: 2005-02-14
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:3526379
Age: embryonic day 12.5
Detected: false
Specimen Num: 2
Publication
First Author: Chung L
Year: 2015
Journal: Oncogene
Title: The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.
Volume: 34
Issue: 7
Pages: 902-11
Publication
First Author: Wang H
Year: 2012
Journal: Aging Cell
Title: Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.
Volume: 11
Issue: 4
Pages: 704-13
Publication
First Author: Drosopoulos WC
Year: 2015
Journal: J Cell Biol
Title: BLM helicase facilitates telomere replication during leading strand synthesis of telomeres.
Volume: 210
Issue: 2
Pages: 191-208
Publication
First Author: Yu Q
Year: 2015
Journal: Cell Rep
Title: DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.
Volume: 11
Issue: 5
Pages: 785-797
Publication
First Author: Dron M
Year: 2000
Journal: Genomics
Title: Mouse scrapie responsive gene 1 (Scrg1): genomic organization, physical linkage to sap30, genetic mapping on chromosome 8, and expression in neuronal primary cell cultures.
Volume: 70
Issue: 1
Pages: 140-9
Publication
First Author: Sebastiani G
Year: 2006
Journal: Hum Mol Genet
Title: Mapping genetic modulators of amyloid plaque deposition in TgCRND8 transgenic mice.
Volume: 15
Issue: 15
Pages: 2313-23
Publication
First Author: McClive PJ
Year: 2003
Journal: Genesis
Title: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Volume: 37
Issue: 2
Pages: 84-90
Publication
First Author: Li Y
Year: 2015
Journal: Nature
Title: Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Volume: 521
Issue: 7553
Pages: 520-4
Publication      
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform