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Search results 1 to 100 out of 109 for Wwp1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
11059 | WWP1
Type: gene
Organism: human
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Gene
100038255 | wwp1
Type: gene
Organism: frog, western clawed
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Gene
297930 | Wwp1
Type: gene
Organism: rat
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Gene
464269 | WWP1
Type: gene
Organism: chimpanzee
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Gene
513789 | WWP1
Type: gene
Organism: cattle
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Gene
100856769 | WWP1
Type: gene
Organism: dog, domestic
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Gene
420212 | WWP1
Type: gene
Organism: chicken
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Gene
694098 | WWP1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1861728 | Wwp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
105375624 | WWP1-AS1
Type: gene
Organism: human
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Publication
34733849 | J:312854
 
First Author: Zhong G
Year: 2021
Journal: Front Cell Dev Biol
Title: WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity.
Volume: 9
Pages: 739944
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Publication
26386426 | J:250962
 
First Author: Basheer WA
Year: 2015
Journal: J Mol Cell Cardiol
Title: Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.
Volume: 88
Pages: 1-13
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Publication
23553732 | J:278539
First Author: Shu L
Year: 2013
Journal: J Bone Miner Res
Title: Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration.
Volume: 28
Issue: 9
Pages: 1925-35
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Publication
19561640 | J:162979
First Author: Li Y
Year: 2009
Journal: Oncogene
Title: WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer.
Volume: 28
Issue: 33
Pages: 2948-58
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Publication
34161574 | J:338992
 
First Author: Lv B
Year: 2021
Journal: J Cell Biol
Title: E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened.
Volume: 220
Issue: 9
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Publication
32822210 | J:298500
First Author: Matesic LE
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart.
Volume: 319
Issue: 4
Pages: H765-H774
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Publication
19047365 | J:162982
First Author: Feng SM
Year: 2009
Journal: Mol Cell Biol
Title: The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation.
Volume: 29
Issue: 3
Pages: 892-906
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Publication
31965758 | J:327431
First Author: Hoshino S
Year: 2020
Journal: FEBS Open Bio
Title: WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism.
Volume: 10
Issue: 3
Pages: 306-315
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Publication
30392800 | J:269370
First Author: Ambrozkiewicz MC
Year: 2018
Journal: Neuron
Title: Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140.
Volume: 100
Issue: 5
Pages: 1097-1115.e15
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Publication
30471861 | J:291527
First Author: Kobayashi M
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Identification of WWP1 as an obesity-associated E3 ubiquitin ligase with a protective role against oxidative stress in adipocytes.
Volume: 508
Issue: 1
Pages: 117-122
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Publication
10903445 | J:63602
First Author: Huang K
Year: 2000
Journal: Gene
Title: A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis.
Volume: 252
Issue: 1-2
Pages: 137-45
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Publication
11375995 | J:114067
First Author: Conkright MD
Year: 2001
Journal: J Biol Chem
Title: Lung Krüppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase.
Volume: 276
Issue: 31
Pages: 29299-306
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Publication
34559578 | J:312851
First Author: Snyder LB
Year: 2021
Journal: Am J Physiol Heart Circ Physiol
Title: Ubiquitin ligase Wwp1 gene deletion attenuates diastolic dysfunction in pressure-overload hypertrophy.
Volume: 321
Issue: 5
Pages: H976-H984
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Publication
16728642 | J:108965
First Author: Jones DC
Year: 2006
Journal: Science
Title: Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.
Volume: 312
Issue: 5777
Pages: 1223-7
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Publication
31097636 | J:277377
 
First Author: Lee YR
Year: 2019
Journal: Science
Title: Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Volume: 364
Issue: 6441
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Publication
21809421 | J:190204
First Author: Zhao L
Year: 2011
Journal: Stem Cells
Title: Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1.
Volume: 29
Issue: 10
Pages: 1601-10
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Publication
23293026 | J:325719
First Author: Lee JO
Year: 2013
Journal: J Biol Chem
Title: E3 ubiquitin ligase, WWP1, interacts with AMPKα2 and down-regulates its expression in skeletal muscle C2C12 cells.
Volume: 288
Issue: 7
Pages: 4673-80
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Publication
30830866 | J:286898
 
First Author: Hirata Y
Year: 2019
Journal: JCI Insight
Title: Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis.
Volume: 4
Issue: 4
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Protein Coding Gene
MGP_CAROLIEiJ_G0025837 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028083 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028052 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027782 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1861728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027314 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023960 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026786 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4844876
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848693
Age: embryonic day 11.5
Note: Staining is present in the interdigital region of the limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4844876
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848693
Age: embryonic day 11.5
Note: Staining is present in the progress zone and middle limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7716465
Assay Type: RNA in situ
Annotation Date: 2024-09-10
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7716474
Age: embryonic day 11.5
Image: 6C
Note: Robust expression was not detected in the developing spinal cord.
Specimen Label: 6C
Specimen Num: 1
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Publication
36002265 | J:352718
First Author: Gorla M
Year: 2022
Journal: J Neurosci
Title: A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.
Volume: 42
Issue: 40
Pages: 7547-7561
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Publication
31845480 | J:284781
First Author: Borna S
Year: 2020
Journal: J Cell Mol Med
Title: Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis.
Volume: 24
Issue: 2
Pages: 1980-1992
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Publication
32027825 | J:284925
     
First Author: Luo L
Year: 2020
Journal: Neuron
Title: Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8BZZ3
Organism: Mus musculus/domesticus
Length: 918  
Fragment?: false
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Gene
471113 | LOC471113
Type: gene
Organism: chimpanzee
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Gene
100613561 | LOC100613561
Type: gene
Organism: chimpanzee
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Gene
103909792 | LOC103909792
Type: gene
Organism: zebrafish
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Protein
Q7TMG3
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: true
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UniProt Feature
UniProt Feature
Begin: 1
Description: NEDD4-like E3 ubiquitin-protein ligase WWP1
Type: chain
End: 918
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Gene
698970 | LOC698970
Type: gene
Organism: macaque, rhesus
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Publication
15735697 | -
First Author: Chen C
Year: 2005
Journal: Oncogene
Title: Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells.
Volume: 24
Issue: 20
Pages: 3319-27
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Publication
18724389 | -
First Author: Chen C
Year: 2008
Journal: Oncogene
Title: The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.
Volume: 27
Issue: 54
Pages: 6845-55
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Allele
Wwp1<em1Smoc> | MGI:7293197
Name: WW domain containing E3 ubiquitin protein ligase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Zhao D (2021)
Description: Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination.
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Publication
15003522 | -
First Author: Zhang X
Year: 2004
Journal: Biochem Biophys Res Commun
Title: WWP1-dependent ubiquitination and degradation of the lung Krüppel-like factor, KLF2.
Volume: 316
Issue: 1
Pages: 139-48
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Strain
MGI:6429805 | C57BL/6JSmoc-Wwp1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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