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Search results 1 to 87 out of 87 for Xaf1

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Hits by Category

Hits by Strain

Type Details Score
Gene
54739 | XAF1
Type: gene
Organism: human
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Gene
119871834 | XAF1
Type: gene
Organism: dog, domestic
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Protein
A0A6G7MAJ9
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: false
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Protein
A0A6G7MA53
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
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Protein
A0A6G7MA55
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: false
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Gene
679600 | Xaf1
Type: gene
Organism: rat
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Gene
455244 | XAF1
Type: gene
Organism: chimpanzee
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Gene
509740 | XAF1
Type: gene
Organism: cattle
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Gene
417677 | XAF1
Type: gene
Organism: chicken
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Gene
767709 | xaf1
Type: gene
Organism: zebrafish
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Gene
713425 | XAF1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3772572 | Xaf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR031220 | XAF1
Type: Family
Description: XAF1 (X-linked inhibitor of apoptosis (XIAP)-associated factor 1) is a proapoptotic protein that antagonises the caspase-inhibitory activity of XIAP [, ]. It is a tumor suppressor that is frequently inactivated in many human cancers. It forms a positive feedback loop with p53 and acts as a molecular switch in p53-mediated cell-fate decisions favoring apoptosis over cell-cycle arrest [].
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Publication
37595039 | J:344340
First Author: Kuang M
Year: 2023
Journal: Sci Adv
Title: XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility.
Volume: 9
Issue: 33
Pages: eadg5211
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Publication
37384528 | J:338549
First Author: Chen M
Year: 2023
Journal: Cell Rep
Title: Identification of XAF1 as an endogenous AKT inhibitor.
Volume: 42
Issue: 7
Pages: 112690
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Publication
35829914 | J:329238
First Author: Nishimura Y
Year: 2022
Journal: Acta Diabetol
Title: XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis.
Volume: 59
Issue: 10
Pages: 1275-1286
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Publication
11175744 | -
First Author: Liston P
Year: 2001
Journal: Nat Cell Biol
Title: Identification of XAF1 as an antagonist of XIAP anti-Caspase activity.
Volume: 3
Issue: 2
Pages: 128-33
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Publication
27097110 | J:310139
First Author: Choo Z
Year: 2016
Journal: Oncotarget
Title: XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosis.
Volume: 7
Issue: 23
Pages: 34229-39
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Publication
36394357 | J:345014
First Author: Liu BQ
Year: 2023
Journal: EMBO Rep
Title: XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7.
Volume: 24
Issue: 1
Pages: e55387
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Publication
17329253 | -
First Author: Straszewski-Chavez SL
Year: 2007
Journal: J Biol Chem
Title: XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway.
Volume: 282
Issue: 17
Pages: 13059-72
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Publication
25313037 | -
First Author: Lee MG
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313.
Volume: 111
Issue: 43
Pages: 15532-7
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Protein
Q5NBU8
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: false
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Protein
Z4YN17
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
F6ZMN8
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
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Publication
30842236 | J:275201
First Author: Zhu C
Year: 2019
Journal: J Exp Med
Title: SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease.
Volume: 216
Issue: 4
Pages: 743-756
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Protein Coding Gene
MGP_CAROLIEiJ_G0016669 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3772572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018360 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019068 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017716 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017802 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017506 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386181
Age: embryonic day 11.5
Image: 3
Specimen Label: wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386181
Age: embryonic day 11.5
Image: 3
Specimen Label: Adar1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386181
Age: embryonic day 11.5
Image: 3
Specimen Label: Adar1-/-;Ifnar1-/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386181
Age: embryonic day 11.5
Image: 3
Specimen Label: Adar1-/-;Mavs-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386223
Age: embryonic day 11.5
Image: S2
Specimen Label: wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386223
Age: embryonic day 11.5
Image: S2
Specimen Label: Ifnar1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6385896
Assay Type: RT-PCR
Annotation Date: 2020-01-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:6386223
Age: embryonic day 11.5
Image: S2
Specimen Label: Mavs-/-
Detected: true
Specimen Num: 3
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Publication
15207275 | J:91241
First Author: Wang X
Year: 2004
Journal: Neurobiol Dis
Title: X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
Volume: 16
Issue: 1
Pages: 179-89
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Publication
25456137 | J:265968
First Author: Mannion NM
Year: 2014
Journal: Cell Rep
Title: The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Volume: 9
Issue: 4
Pages: 1482-94
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
22811387 | -
First Author: Tse MK
Year: 2012
Journal: Protein Sci
Title: Domain organization of XAF1 and the identification and characterization of XIAP(RING) -binding domain of XAF1.
Volume: 21
Issue: 10
Pages: 1418-28
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Protein Domain
IPR041386 | XAF1_C
Type: Domain
Description: XIAP-associated factor 1 (XAF1) is a 301-amino acid interferon (INF)-inducible pro-apoptotic protein. This entry represents the C-terminal domain which is functionally identified as XIAP(RING)-binding domain of XAF1 [].
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Publication
32268088 | J:300476
First Author: Uccellini MB
Year: 2020
Journal: Cell Rep
Title: Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice.
Volume: 31
Issue: 1
Pages: 107498
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Publication
39657676 | J:361350
First Author: Mei W
Year: 2025
Journal: Cell
Title: A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor.
Volume: 188
Issue: 2
Pages: 371-389.e28
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HT Experiment
E-GEOD-60414 | Potentiation of neurotoxicity in double mutant mice with Pink1 ablation and A53T-SNCA overexpression
Series Id: GSE60414
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
25296918 | J:214065
First Author: Gispert S
Year: 2015
Journal: Hum Mol Genet
Title: Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression.
Volume: 24
Issue: 4
Pages: 1061-76
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Publication
27733608 | J:236299
First Author: Ou Z
Year: 2016
Journal: J Neurosci
Title: Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination.
Volume: 36
Issue: 41
Pages: 10560-10573
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