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Search results 1 to 100 out of 936 for Xbp1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
7494 | XBP1
Type: gene
Organism: human
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Gene
407858 | xbp1
Type: gene
Organism: frog, western clawed
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Gene
289754 | Xbp1
Type: gene
Organism: rat
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Gene
458735 | XBP1
Type: gene
Organism: chimpanzee
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Gene
477532 | XBP1
Type: gene
Organism: dog, domestic
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Gene
541236 | XBP1
Type: gene
Organism: cattle
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Gene
416918 | XBP1
Type: gene
Organism: chicken
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Gene
140614 | xbp1
Type: gene
Organism: zebrafish
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Gene
713863 | XBP1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:98970 | Xbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:3820951
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826172
Age: embryonic day 14.5
Image: Additional file 4 Xbp1
Specimen Label: Additional file 4 Xbp1
Detected: true
Specimen Num: 1
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Publication
33891366 | J:314673
First Author: Xu Q
Year: 2021
Journal: Genesis
Title: Constitutive expression of spliced XBP1 causes perinatal lethality in mice.
Volume: 59
Issue: 5-6
Pages: e23420
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Publication
23623498 | J:198494
First Author: Gregor MF
Year: 2013
Journal: Cell Rep
Title: The role of adipocyte XBP1 in metabolic regulation during lactation.
Volume: 3
Issue: 5
Pages: 1430-9
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Publication
17612490 | J:215889
First Author: Acosta-Alvear D
Year: 2007
Journal: Mol Cell
Title: XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks.
Volume: 27
Issue: 1
Pages: 53-66
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Publication
21704586 | J:198904
First Author: Hess DA
Year: 2011
Journal: Gastroenterology
Title: Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice.
Volume: 141
Issue: 4
Pages: 1463-72
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Publication
25844898 | J:222413
First Author: Fedeles SV
Year: 2015
Journal: J Clin Invest
Title: Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.
Volume: 125
Issue: 5
Pages: 1955-67
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Publication
26147683 | J:239648
First Author: Bettigole SE
Year: 2015
Journal: Nat Immunol
Title: The transcription factor XBP1 is selectively required for eosinophil differentiation.
Volume: 16
Issue: 8
Pages: 829-37
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Publication
39650729 | J:360627
First Author: Joshi AS
Year: 2024
Journal: iScience
Title: Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis.
Volume: 27
Issue: 12
Pages: 111372
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Publication
23529610 | J:211440
First Author: Zeng L
Year: 2013
Journal: Circulation
Title: Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis.
Volume: 127
Issue: 16
Pages: 1712-22
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Publication
29615095 | J:277049
First Author: McLaughlin T
Year: 2018
Journal: Mol Neurodegener
Title: Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration.
Volume: 13
Issue: 1
Pages: 16
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Publication
18775308 | J:188627
First Author: Kaser A
Year: 2008
Journal: Cell
Title: XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.
Volume: 134
Issue: 5
Pages: 743-56
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Publication
15882996 | J:98283
First Author: Kanemoto S
Year: 2005
Journal: Biochem Biophys Res Commun
Title: XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress.
Volume: 331
Issue: 4
Pages: 1146-53
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Publication
31242599 | J:281073
 
First Author: McLaughlin T
Year: 2019
Journal: J Clin Med
Title: Loss of XBP1 Leads to Early-Onset Retinal Neurodegeneration in a Mouse Model of Type I Diabetes.
Volume: 8
Issue: 6
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Publication
33277471 | J:300965
First Author: Meng H
Year: 2020
Journal: Nat Commun
Title: XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis.
Volume: 11
Issue: 1
Pages: 6215
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Publication
26504083 | J:264173
First Author: Olivares S
Year: 2015
Journal: J Biol Chem
Title: Hepatic Xbp1 Gene Deletion Promotes Endoplasmic Reticulum Stress-induced Liver Injury and Apoptosis.
Volume: 290
Issue: 50
Pages: 30142-51
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Publication
25713103 | J:224417
First Author: Hasegawa D
Year: 2015
Journal: Mol Cell Biol
Title: Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development.
Volume: 35
Issue: 9
Pages: 1543-56
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Publication
38015176 | J:343317
First Author: McLaughlin T
Year: 2023
Journal: Invest Ophthalmol Vis Sci
Title: Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy.
Volume: 64
Issue: 14
Pages: 40
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Publication
34975335 | J:340234
First Author: Li X
Year: 2022
Journal: Int J Biol Sci
Title: Effect Of XBP1 Deficiency In Cartilage On The Regulatory Network Of LncRNA/circRNA-miRNA-mRNA.
Volume: 18
Issue: 1
Pages: 315-330
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Publication
36801911 | J:334574
First Author: Ni H
Year: 2023
Journal: Cell Death Discov
Title: XBP1 modulates endoplasmic reticulum and mitochondria crosstalk via regulating NLRP3 in renal ischemia/reperfusion injury.
Volume: 9
Issue: 1
Pages: 69
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Publication
35145060 | J:333656
First Author: Ye H
Year: 2022
Journal: Cell Death Dis
Title: Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy.
Volume: 13
Issue: 2
Pages: 143
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Publication
16644724 | J:114578
First Author: Back SH
Year: 2006
Journal: J Biol Chem
Title: Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress.
Volume: 281
Issue: 27
Pages: 18691-706
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Publication
27338006 | J:259559
 
First Author: Zhao Y
Year: 2016
Journal: Sci Rep
Title: XBP1 splicing triggers miR-150 transfer from smooth muscle cells to endothelial cells via extracellular vesicles.
Volume: 6
Pages: 28627
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191579
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Xbp1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191579
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Xbp1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191579
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Xbp1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191579
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Xbp1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191579
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Xbp1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191579
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Xbp1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6186916
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191579
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Xbp1
Detected: true
Specimen Num: 7
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Publication
17890727 | J:145222
First Author: Hayashi A
Year: 2007
Journal: J Biol Chem
Title: The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development.
Volume: 282
Issue: 47
Pages: 34525-34
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Publication
32788214 | J:298919
First Author: Sharma RB
Year: 2020
Journal: J Biol Chem
Title: Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.
Volume: 295
Issue: 41
Pages: 14164-14177
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Publication
31260448 | J:277397
First Author: Piróg KA
Year: 2019
Journal: PLoS Genet
Title: XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease.
Volume: 15
Issue: 7
Pages: e1008215
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Publication
29089350 | J:322338
First Author: Zhao G
Year: 2017
Journal: Circ Res
Title: Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction.
Volume: 121
Issue: 12
Pages: 1331-1345
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Publication
20351694 | J:158967
First Author: Martinon F
Year: 2010
Journal: Nat Immunol
Title: TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.
Volume: 11
Issue: 5
Pages: 411-8
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Publication
23184933 | J:215858
First Author: Margariti A
Year: 2013
Journal: J Biol Chem
Title: XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation.
Volume: 288
Issue: 2
Pages: 859-72
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Publication
33654072 | J:308364
First Author: Zhang J
Year: 2021
Journal: Cell Death Discov
Title: Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation.
Volume: 7
Issue: 1
Pages: 44
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Publication
24043762 | J:204069
First Author: Niederreiter L
Year: 2013
Journal: J Exp Med
Title: ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells.
Volume: 210
Issue: 10
Pages: 2041-56
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Publication
30745418 | J:293109
     
First Author: Ishikawa Y
Year: 2019
Journal: J Am Soc Nephrol
Title: Spliced XBP1 Rescues Renal Interstitial Inflammation Due to Loss of Sec63 in Collecting Ducts.
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Publication
22431749 | J:185049
First Author: Byrd AE
Year: 2012
Journal: J Cell Biol
Title: MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response.
Volume: 196
Issue: 6
Pages: 689-98
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Publication
32926479 | J:301663
First Author: Saraswat Ohri S
Year: 2021
Journal: Glia
Title: Oligodendrocyte-specific deletion of Xbp1 exacerbates the endoplasmic reticulum stress response and restricts locomotor recovery after thoracic spinal cord injury.
Volume: 69
Issue: 2
Pages: 424-435
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Publication
26562262 | J:233630
First Author: Davis KR
Year: 2016
Journal: Endocrinology
Title: XBP1 Regulates the Biosynthetic Capacity of the Mammary Gland During Lactation by Controlling Epithelial Expansion and Endoplasmic Reticulum Formation.
Volume: 157
Issue: 1
Pages: 417-28
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Publication
20692302 | J:166170
First Author: Takata A
Year: 2010
Journal: Neurosci Res
Title: Behavioral and gene expression analyses in heterozygous XBP1 knockout mice: Possible contribution of chromosome 11qA1 locus to prepulse inhibition.
Volume: 68
Issue: 3
Pages: 250-5
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Publication
35367811 | J:337807
 
First Author: Liu Z
Year: 2022
Journal: Redox Biol
Title: XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury.
Volume: 52
Pages: 102305
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Publication
19752183 | J:153424
First Author: Todd DJ
Year: 2009
Journal: J Exp Med
Title: XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development.
Volume: 206
Issue: 10
Pages: 2151-9
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Publication
22337954 | J:183791
First Author: Vidal RL
Year: 2012
Journal: Hum Mol Genet
Title: Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.
Volume: 21
Issue: 10
Pages: 2245-62
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Publication
19416856 | J:148530
First Author: Zeng L
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow.
Volume: 106
Issue: 20
Pages: 8326-31
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Publication
37753803 | J:342566
First Author: Salimi A
Year: 2023
Journal: J Cell Mol Med
Title: XBP1 promotes NRAS(G12D) pre-B acute lymphoblastic leukaemia through IL-7 receptor signalling and provides a therapeutic vulnerability for oncogenic RAS.
Volume: 27
Issue: 21
Pages: 3363-3377
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Publication
35316840 | J:328304
First Author: Lee K
Year: 2022
Journal: Diabetologia
Title: XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.
Volume: 65
Issue: 6
Pages: 984-996
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Publication
21555585 | J:171889
First Author: Lee AH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.
Volume: 108
Issue: 21
Pages: 8885-90
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Publication
29482168 | J:273678
 
First Author: Zhang M
Year: 2018
Journal: Redox Biol
Title: Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.
Volume: 16
Pages: 87-96
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Publication
25600960 | J:231358
First Author: Cameron TL
Year: 2015
Journal: Osteoarthritis Cartilage
Title: Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization.
Volume: 23
Issue: 4
Pages: 661-70
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Protein
Q05DE6
Organism: Mus musculus/domesticus
Length: 356  
Fragment?: false
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Publication
30973754 | J:291138
First Author: Chen G
Year: 2019
Journal: Am J Respir Crit Care Med
Title: XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia.
Volume: 200
Issue: 2
Pages: 220-234
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Publication
38274041 | J:360114
 
First Author: Xu Q
Year: 2023
Journal: Front Physiol
Title: Constitutive expression of spliced X-box binding protein 1 inhibits dentin formation in mice.
Volume: 14
Pages: 1319954
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Publication
24630721 | J:211997
First Author: Wang ZV
Year: 2014
Journal: Cell
Title: Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway.
Volume: 156
Issue: 6
Pages: 1179-1192
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Publication
33600817 | J:306948
 
First Author: Wang Z
Year: 2021
Journal: Exp Neurol
Title: Increasing O-GlcNAcylation is neuroprotective in young and aged brains after ischemic stroke.
Volume: 339
Pages: 113646
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Publication
14702639 | J:87202
First Author: Iwawaki T
Year: 2004
Journal: Nat Med
Title: A transgenic mouse model for monitoring endoplasmic reticulum stress.
Volume: 10
Issue: 1
Pages: 98-102
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Publication
28459443 | J:246202
First Author: Tavernier SJ
Year: 2017
Journal: Nat Cell Biol
Title: Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.
Volume: 19
Issue: 6
Pages: 698-710
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Publication
37346037 | J:336913
 
First Author: Flores-Santibañez F
Year: 2023
Journal: Front Immunol
Title: Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity.
Volume: 14
Pages: 1209588
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Publication
31601454 | J:297942
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
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Publication
21357531 | J:171455
First Author: Thorp E
Year: 2011
Journal: J Lipid Res
Title: A reporter for tracking the UPR in vivo reveals patterns of temporal and cellular stress during atherosclerotic progression.
Volume: 52
Issue: 5
Pages: 1033-8
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Publication
29551634 | J:260830
     
First Author: Deng Y
Year: 2018
Journal: Mol Metab
Title: Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.
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Publication
18556558 | J:137188
First Author: Lee AH
Year: 2008
Journal: Science
Title: Regulation of hepatic lipogenesis by the transcription factor XBP1.
Volume: 320
Issue: 5882
Pages: 1492-6
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Publication
29157602 | J:263519
First Author: Olivares S
Year: 2017
Journal: Mol Metab
Title: Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice.
Volume: 6
Issue: 12
Pages: 1616-1624
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Publication
18809377 | J:142834
First Author: Hayashi A
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1.
Volume: 376
Issue: 4
Pages: 758-63
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Publication
28747426 | J:249576
First Author: Hosomi S
Year: 2017
Journal: J Exp Med
Title: Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.
Volume: 214
Issue: 10
Pages: 2985-2997
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Publication
34686867 | J:321393
First Author: Di Conza G
Year: 2021
Journal: Nat Immunol
Title: Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Volume: 22
Issue: 11
Pages: 1403-1415
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Publication
19135031 | J:148221
 
First Author: Sado M
Year: 2009
Journal: Brain Res
Title: Protective effect against Parkinson's disease-related insults through the activation of XBP1.
Volume: 1257
Pages: 16-24
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Publication
32065579 | J:290683
   
First Author: Hinte F
Year: 2020
Journal: Elife
Title: Repression of viral gene expression and replication by the unfolded protein response effector XBP1u.
Volume: 9
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Publication
24753614 | J:211083
First Author: Valdés P
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1.
Volume: 111
Issue: 18
Pages: 6804-9
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Publication
30482806 | J:271718
First Author: Olivares S
Year: 2019
Journal: J Lipid Res
Title: The role of X-box binding protein 1 in the hepatic response to refeeding in mice.
Volume: 60
Issue: 2
Pages: 353-359
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Publication
23493568 | J:208668
First Author: Akiyama M
Year: 2013
Journal: Diabetes
Title: X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function.
Volume: 62
Issue: 7
Pages: 2439-49
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Publication
26472223 | J:318911
First Author: Liu X
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet.
Volume: 309
Issue: 12
Pages: G965-74
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Publication
22715395 | J:187835
First Author: Zhong Y
Year: 2012
Journal: PLoS One
Title: X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium.
Volume: 7
Issue: 6
Pages: e38616
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Publication
27701635 | J:254699
First Author: Ma JH
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions.
Volume: 57
Issue: 13
Pages: 5244-5252
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Publication
19247368 | J:164189
First Author: Liu Y
Year: 2009
Journal: Cell Death Differ
Title: Preventing oxidative stress: a new role for XBP1.
Volume: 16
Issue: 6
Pages: 847-57
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Publication
35263593 | J:324899
First Author: Meng H
Year: 2022
Journal: Cell Rep
Title: Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism.
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