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Search results 1 to 100 out of 108 for Xirp1

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0.038s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wang Q
Year: 2013
Journal: Dev Biol
Title: The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.
Volume: 374
Issue: 2
Pages: 264-80
Publication
First Author: Leber Y
Year: 2016
Journal: Hum Mol Genet
Title: Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage.
Volume: 25
Issue: 13
Pages: 2776-2788
Publication
First Author: Sinn HW
Year: 2002
Journal: Dev Dyn
Title: Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development.
Volume: 225
Issue: 1
Pages: 1-13
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kebir S
Year: 2016
Journal: Exp Cell Res
Title: Sarcomeric lesions and remodeling proximal to intercalated disks in overload-induced cardiac hypertrophy.
Volume: 348
Issue: 1
Pages: 95-105
Publication
First Author: Feng HZ
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Localization and function of Xinα in mouse skeletal muscle.
Volume: 304
Issue: 10
Pages: C1002-12
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1334545
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1334551
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1334547
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1334553
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5691547
Assay Type: RT-PCR
Annotation Date: 2015-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5691548
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5691547
Assay Type: RT-PCR
Annotation Date: 2015-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5691548
Age: embryonic day 9.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:241925
Assay Type: Northern blot
Annotation Date: 1999-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1334556
Age: postnatal adult
Image: 8
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3789109
Assay Type: RNA in situ
Annotation Date: 2008-05-23
Strength: Present
Sex: Male
Emaps: EMAPS:1770128
Pattern: Patchy
Stage: TS28
Assay Id: MGI:3789124
Age: postnatal adult
Note: Expression is present in focal regions.
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3789109
Assay Type: RNA in situ
Annotation Date: 2008-05-23
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3268815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3789124
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3789109
Assay Type: RNA in situ
Annotation Date: 2008-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3789124
Age: embryonic day 13.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3789109
Assay Type: RNA in situ
Annotation Date: 2008-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3789124
Age: embryonic day 15.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3789109
Assay Type: RNA in situ
Annotation Date: 2008-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3789124
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1334546
Assay Type: RNA in situ
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1686021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:1334561
Age: embryonic day 13.0
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3789108
Assay Type: Immunohistochemistry
Annotation Date: 2008-05-23
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3789125
Age: postnatal adult
Note: Expression is present in satellite cells.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1334565
Assay Type: Immunohistochemistry
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:1334568
Age: postnatal adult
Image: 9B
Note: Expression was detected in a banded pattern. The majority of bands stained are colocalized with connexin-43, known to locate in the intercalated discs.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1334565
Assay Type: Immunohistochemistry
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:1334568
Age: postnatal adult
Image: 9D
Note: Expression was detected in a banded pattern. The majority of bands stained are colocalized with N-cadherin, known to locate in the intercalated discs.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1334565
Assay Type: Immunohistochemistry
Annotation Date: 1999-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:1334568
Age: postnatal adult
Image: 9F
Note: Expression was detected in a banded pattern.
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5691549
Assay Type: RNA in situ
Annotation Date: 2015-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5691550
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3789109
Assay Type: RNA in situ
Annotation Date: 2008-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1788321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3789124
Age: embryonic day 13.5
Detected: true
Specimen Num: 2
Publication
First Author: Otten J
Year: 2010
Journal: Cardiovasc Res
Title: Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs.
Volume: 85
Issue: 4
Pages: 739-50
Publication
First Author: Jung-Ching Lin J
Year: 2005
Journal: J Med Sci
Title: Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin.
Volume: 25
Issue: 5
Pages: 215-222
Publication
First Author: Grosskurth SE
Year: 2008
Journal: PLoS One
Title: Emergence of Xin demarcates a key innovation in heart evolution.
Volume: 3
Issue: 8
Pages: e2857
Publication
First Author: Choi S
Year: 2007
Journal: J Biol Chem
Title: The intercalated disk protein, mXinalpha, is capable of interacting with beta-catenin and bundling actin filaments [corrected].
Volume: 282
Issue: 49
Pages: 36024-36
Publication
First Author: Wang Q
Year: 2013
Journal: Arch Biochem Biophys
Title: Intercalated disc protein, mXinα, suppresses p120-catenin-induced branching phenotype via its interactions with p120-catenin and cortactin.
Volume: 535
Issue: 1
Pages: 91-100
Publication
First Author: Wang DZ
Year: 1999
Journal: Development
Title: Requirement of a novel gene, Xin, in cardiac morphogenesis.
Volume: 126
Issue: 6
Pages: 1281-94
Publication
First Author: Hawke TJ
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers.
Volume: 293
Issue: 5
Pages: C1636-44
Publication  
First Author: Sharma P
Year: 2015
Journal: Nat Commun
Title: Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.
Volume: 6
Pages: 8391
Publication
First Author: Gustafson-Wagner EA
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.
Volume: 293
Issue: 5
Pages: H2680-92
Publication
First Author: Fouillade C
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.
Volume: 33
Issue: 1
Pages: 76-86
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Eulitz S
Year: 2013
Journal: Mol Biol Cell
Title: Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.
Volume: 24
Issue: 20
Pages: 3215-26
Publication
First Author: Molt S
Year: 2014
Journal: J Cell Sci
Title: Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance.
Volume: 127
Issue: Pt 16
Pages: 3578-92
Protein Domain
Type: Family
Description: Proteins in this family contains Xin repeats, which define an actin-binding motif. In humans two Xin-repeat proteins have been identified, XIRP1 and XIRP2. They are expressed during early developmental stages of cardiac and skeletal muscles []and have an important role in cardiac development and function []. They bind to and stabilise F-actin [].The homologues in mouse and chicken localise in the adherens junction complex of the intercalated disc in cardiac muscle and in the myotendon junction of skeletal muscle. Mouse Xin may co-localise with Vinculin which is known to attach the actin to the cytoplasmic membrane []. Human XIRP1 binds the EVH1 domains of Ena/VASP proteins and filamin C []. It also binds the SH3 domain of nebulin and nebulette []. The multiplicity of binding partners suggests that Xin acts as a multi-adaptor protein during myofibril development and repair [].
Protein Domain
Type: Family
Description: Proteins in this family contains Xin repeats, which define an actin-binding motif. In humans two Xin-repeat proteins have been identified, XIRP1 and XIRP2. They are expressed during early developmental stages of cardiac and skeletal muscles []and have an important role in cardiac development and function []. They bind to and stabilise F-actin [].This entry represents XIRP2, also known as Xin-beta. In mouse, it initiates the maturation of the intercalated discs (ICDs)during postnatal heart development [].
Protein
Organism: Mus musculus
Length: 67  
Fragment?: true
Protein
Organism: Mus musculus
Length: 101  
Fragment?: true
Protein
Organism: Mus musculus
Length: 119  
Fragment?: true
Protein
Organism: Mus musculus
Length: 374  
Fragment?: true
Protein
Organism: Mus musculus
Length: 118  
Fragment?: true
Publication
First Author: Pacholsky D
Year: 2004
Journal: J Cell Sci
Title: Xin repeats define a novel actin-binding motif.
Volume: 117
Issue: Pt 22
Pages: 5257-68
Publication  
First Author: Wang Q
Year: 2014
Journal: Int Rev Cell Mol Biol
Title: New insights into the roles of Xin repeat-containing proteins in cardiac development, function, and disease.
Volume: 310
Pages: 89-128
Protein
Organism: Mus musculus
Length: 284  
Fragment?: true
Protein
Organism: Mus musculus
Length: 3512  
Fragment?: false
Publication
First Author: van der Ven PF
Year: 2006
Journal: Exp Cell Res
Title: Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.
Volume: 312
Issue: 11
Pages: 2154-67
Protein
Organism: Mus musculus
Length: 1129  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1132  
Fragment?: false
Protein
Organism: Mus musculus
Length: 77  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1813  
Fragment?: false