Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Q |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development. |
Volume: |
374 |
Issue: |
2 |
Pages: |
264-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leber Y |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage. |
Volume: |
25 |
Issue: |
13 |
Pages: |
2776-2788 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sinn HW |
Year: |
2002 |
Journal: |
Dev Dyn |
Title: |
Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development. |
Volume: |
225 |
Issue: |
1 |
Pages: |
1-13 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng HZ |
Year: |
2013 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Localization and function of Xinα in mouse skeletal muscle. |
Volume: |
304 |
Issue: |
10 |
Pages: |
C1002-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al-Sajee D |
Year: |
2015 |
Journal: |
Acta Physiol (Oxf) |
Title: |
Xin-deficient mice display myopathy, impaired contractility, attenuated muscle repair and altered satellite cell functionality. |
Volume: |
214 |
Issue: |
2 |
Pages: |
248-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kebir S |
Year: |
2016 |
Journal: |
Exp Cell Res |
Title: |
Sarcomeric lesions and remodeling proximal to intercalated disks in overload-induced cardiac hypertrophy. |
Volume: |
348 |
Issue: |
1 |
Pages: |
95-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li C |
Year: |
2021 |
Journal: |
Acta Biochim Biophys Sin (Shanghai) |
Title: |
Effects of CMYA1 overexpression on cardiac structure and function in mice. |
Volume: |
53 |
Issue: |
5 |
Pages: |
593-600 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1334545 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334551 |
Age: |
postnatal adult |
Image: |
4 |
|
Specimen Label: |
A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1334547 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334553 |
Age: |
postnatal adult |
Image: |
4 |
|
Specimen Label: |
B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Heart |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Brain |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Spleen |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Lung |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Liver |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Skeletal Muscle |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Kidney |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:241925 |
Assay Type: |
Northern blot |
Annotation Date: |
1999-04-21 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:1334556 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Testis |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5691547 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-10-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:5691548 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5691547 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-10-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:5691548 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789109 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-23 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1770128 |
Pattern: |
Patchy |
Stage: |
TS28 |
Assay Id: |
MGI:3789124 |
Age: |
postnatal adult |
|
Note: |
Expression is present in focal regions. |
Specimen Label: |
3I |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789109 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-23 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268815 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:3789124 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
1B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789109 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3789124 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
1F |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789109 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:3789124 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789109 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3789124 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1334546 |
Assay Type: |
RNA in situ |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1686021 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:1334561 |
Age: |
embryonic day 13.0 |
|
|
Specimen Label: |
day 13 embryo |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789108 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-05-23 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3598828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3789125 |
Age: |
postnatal adult |
|
Note: |
Expression is present in satellite cells. |
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1334565 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:1334568 |
Age: |
postnatal adult |
Image: |
9B |
Note: |
Expression was detected in a banded pattern. The majority of bands stained are colocalized with connexin-43, known to locate in the intercalated discs. |
Specimen Label: |
9B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1334565 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:1334568 |
Age: |
postnatal adult |
Image: |
9D |
Note: |
Expression was detected in a banded pattern. The majority of bands stained are colocalized with N-cadherin, known to locate in the intercalated discs. |
Specimen Label: |
9D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1334565 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
1999-04-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:1334568 |
Age: |
postnatal adult |
Image: |
9F |
Note: |
Expression was detected in a banded pattern. |
Specimen Label: |
9F |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5691549 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-10-15 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610515 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:5691550 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
2B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3789109 |
Assay Type: |
RNA in situ |
Annotation Date: |
2008-05-23 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1788321 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3789124 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
1F |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung-Ching Lin J |
Year: |
2005 |
Journal: |
J Med Sci |
Title: |
Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin. |
Volume: |
25 |
Issue: |
5 |
Pages: |
215-222 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grosskurth SE |
Year: |
2008 |
Journal: |
PLoS One |
Title: |
Emergence of Xin demarcates a key innovation in heart evolution. |
Volume: |
3 |
Issue: |
8 |
Pages: |
e2857 |
|
•
•
•
•
•
|
Publication |
First Author: |
Otten J |
Year: |
2010 |
Journal: |
Cardiovasc Res |
Title: |
Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs. |
Volume: |
85 |
Issue: |
4 |
Pages: |
739-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi S |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
The intercalated disk protein, mXinalpha, is capable of interacting with beta-catenin and bundling actin filaments [corrected]. |
Volume: |
282 |
Issue: |
49 |
Pages: |
36024-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Q |
Year: |
2013 |
Journal: |
Arch Biochem Biophys |
Title: |
Intercalated disc protein, mXinα, suppresses p120-catenin-induced branching phenotype via its interactions with p120-catenin and cortactin. |
Volume: |
535 |
Issue: |
1 |
Pages: |
91-100 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang DZ |
Year: |
1999 |
Journal: |
Development |
Title: |
Requirement of a novel gene, Xin, in cardiac morphogenesis. |
Volume: |
126 |
Issue: |
6 |
Pages: |
1281-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hawke TJ |
Year: |
2007 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers. |
Volume: |
293 |
Issue: |
5 |
Pages: |
C1636-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sharma P |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. |
Volume: |
6 |
|
Pages: |
8391 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gustafson-Wagner EA |
Year: |
2007 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. |
Volume: |
293 |
Issue: |
5 |
Pages: |
H2680-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fouillade C |
Year: |
2013 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature. |
Volume: |
33 |
Issue: |
1 |
Pages: |
76-86 |
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Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
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Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
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Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Eulitz S |
Year: |
2013 |
Journal: |
Mol Biol Cell |
Title: |
Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling. |
Volume: |
24 |
Issue: |
20 |
Pages: |
3215-26 |
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Publication |
First Author: |
Molt S |
Year: |
2014 |
Journal: |
J Cell Sci |
Title: |
Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance. |
Volume: |
127 |
Issue: |
Pt 16 |
Pages: |
3578-92 |
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Protein Domain |
Type: |
Family |
Description: |
Proteins in this family contains Xin repeats, which define an actin-binding motif. In humans two Xin-repeat proteins have been identified, XIRP1 and XIRP2. They are expressed during early developmental stages of cardiac and skeletal muscles []and have an important role in cardiac development and function []. They bind to and stabilise F-actin [].The homologues in mouse and chicken localise in the adherens junction complex of the intercalated disc in cardiac muscle and in the myotendon junction of skeletal muscle. Mouse Xin may co-localise with Vinculin which is known to attach the actin to the cytoplasmic membrane []. Human XIRP1 binds the EVH1 domains of Ena/VASP proteins and filamin C []. It also binds the SH3 domain of nebulin and nebulette []. The multiplicity of binding partners suggests that Xin acts as a multi-adaptor protein during myofibril development and repair []. |
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Protein Domain |
Type: |
Family |
Description: |
Proteins in this family contains Xin repeats, which define anactin-binding motif. In humans two Xin-repeat proteins have been identified, XIRP1 and XIRP2. They are expressed during early developmental stages of cardiac and skeletal muscles []and have an important role in cardiac development and function []. They bind to and stabilise F-actin [].This entry represents XIRP2, also known as Xin-beta. In mouse, it initiates the maturation of the intercalated discs (ICDs)during postnatal heart development []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
101
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Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
374
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
119
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
118
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
67
 |
Fragment?: |
true |
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Publication |
First Author: |
Pacholsky D |
Year: |
2004 |
Journal: |
J Cell Sci |
Title: |
Xin repeats define a novel actin-binding motif. |
Volume: |
117 |
Issue: |
Pt 22 |
Pages: |
5257-68 |
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