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Search results 1 to 86 out of 86 for Xkr8

0.028s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Sakuragi T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure.
Volume: 116
Issue: 8
Pages: 2907-2912
Publication
First Author: Chen K
Year: 2023
Journal: J Transl Med
Title: A dominant variant in apoptosis-related gene XKR8 is relevant to hereditary auditory neuropathy.
Volume: 21
Issue: 1
Pages: 279
Publication
First Author: Neniskyte U
Year: 2023
Journal: EMBO J
Title: Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure.
Volume: 42
Issue: 14
Pages: e111790
Publication  
First Author: Kautzman AG
Year: 2018
Journal: Front Neurosci
Title: Xkr8 Modulates Bipolar Cell Number in the Mouse Retina.
Volume: 12
Pages: 876
Publication
First Author: Suzuki J
Year: 2013
Journal: Science
Title: Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.
Volume: 341
Issue: 6144
Pages: 403-6
Publication
First Author: Kim GW
Year: 2017
Journal: FEBS J
Title: Xk-related protein 8 regulates myoblast differentiation and survival.
Volume: 284
Issue: 21
Pages: 3575-3588
Publication
First Author: Kawano M
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase.
Volume: 115
Issue: 9
Pages: 2132-2137
Publication  
First Author: Yamashita Y
Year: 2020
Journal: Mol Cell Biol
Title: Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in Xkr8-Deficient Male Mice.
Volume: 40
Issue: 3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Suzuki J
Year: 2014
Journal: J Biol Chem
Title: Exposure of phosphatidylserine by Xk-related protein family members during apoptosis.
Volume: 289
Issue: 44
Pages: 30257-67
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Suzuki J
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.
Volume: 113
Issue: 34
Pages: 9509-14
Publication
First Author: Wang W
Year: 2022
Journal: Cell Rep
Title: Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Volume: 41
Issue: 5
Pages: 111582
Protein
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 647  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 638  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
Publication
First Author: Ho M
Year: 1994
Journal: Cell
Title: Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein.
Volume: 77
Issue: 6
Pages: 869-80
Publication
First Author: Khamlichi S
Year: 1995
Journal: Eur J Biochem
Title: Purification and partial characterization of the erythrocyte Kx protein deficient in McLeod patients.
Volume: 228
Issue: 3
Pages: 931-4
Publication
First Author: Park JS
Year: 2020
Journal: Mol Biol Cell
Title: XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome.
Volume: 31
Issue: 22
Pages: 2425-2436
Protein Domain
Type: Family
Description: This family is represented by the multipass membrane protein XK, which may be involved in sodium-dependent transport of neutral amino acids or oligopeptides. It forms a heterodimer with Kell. In humans, Kell is an 93kDa type II membrane glycoprotein with endothelin-3-converting enzyme activity that is linked by a single disulphide bond to XK, that spans the membrane ten times. An absence of XK leads to clinical symptoms termed the McLeod syndrome , an X-linked multi-system disorder characterised by late onset abnormalities in the neuromuscular and hematopoietic systems [, ]. It has been shown that XK recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane and dysregulation of a VPS13A-XK complex is the common basis for Chorea-Acanthocytosis and McLeod Syndrome []. The human and mouse Xk-related (Xkr) families consist of nine and eight members, respectively, and mutations or variations in the gene of Xkr members are associated to human diseases. Xkr8 and other members of the family promote phosphatidylserine exposure in apoptotic cells [, , ].