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Search results 1 to 100 out of 188 for Xrcc5

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen DJ
Year: 1992
Journal: Genomics
Title: Assignment of a human DNA double-strand break repair gene (XRCC5) to chromosome 2.
Volume: 13
Issue: 4
Pages: 1088-94
Publication
First Author: He DM
Year: 1996
Journal: Mutat Res
Title: Restoration of X-ray and etoposide resistance, Ku-end binding activity and V(D) J recombination to the Chinese hamster sxi-3 mutant by a hamster Ku86 cDNA.
Volume: 363
Issue: 1
Pages: 43-56
Publication
First Author: Cai X
Year: 2023
Journal: Cell Death Dis
Title: Xrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes.
Volume: 14
Issue: 7
Pages: 397
Publication  
First Author: Ratnayaka-Gamage ND
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Xrcc5/KU80 is not required for the survival or activation of prophase-arrested oocytes in primordial follicles.
Volume: 14
Pages: 1268009
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for durio.
Publication
First Author: Zhu C
Year: 1996
Journal: Cell
Title: Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates.
Volume: 86
Issue: 3
Pages: 379-89
Publication
First Author: Karanjawala ZE
Year: 2003
Journal: DNA Repair (Amst)
Title: Developmental retinal apoptosis in Ku86-/- mice.
Volume: 2
Issue: 12
Pages: 1429-34
Publication
First Author: Espejel S
Year: 2002
Journal: EMBO J
Title: Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.
Volume: 21
Issue: 9
Pages: 2207-19
Publication
First Author: Vogel H
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Deletion of Ku86 causes early onset of senescence in mice.
Volume: 96
Issue: 19
Pages: 10770-5
Publication
First Author: Bogue MA
Year: 1997
Journal: Immunity
Title: V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation.
Volume: 7
Issue: 1
Pages: 37-47
Publication
First Author: Nussenzweig A
Year: 1996
Journal: Nature
Title: Requirement for Ku80 in growth and immunoglobulin V(D)J recombination.
Volume: 382
Issue: 6591
Pages: 551-5
Publication
First Author: Rockwood LD
Year: 2003
Journal: Mutat Res
Title: Paradoxical decrease in mutant frequencies and chromosomal rearrangements in a transgenic lacZ reporter gene in Ku80 null mice deficient in DNA double strand break repair.
Volume: 529
Issue: 1-2
Pages: 51-8
Publication
First Author: Dmitrieva NI
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Ku86 preserves chromatin integrity in cells adapted to high NaCl.
Volume: 102
Issue: 30
Pages: 10730-5
Publication
First Author: Casellas R
Year: 1998
Journal: EMBO J
Title: Ku80 is required for immunoglobulin isotype switching.
Volume: 17
Issue: 8
Pages: 2404-11
Publication
First Author: Nussenzweig A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development.
Volume: 94
Issue: 25
Pages: 13588-93
Publication
First Author: Wachsberger PR
Year: 1999
Journal: Radiat Res
Title: Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts.
Volume: 151
Issue: 4
Pages: 398-407
Publication
First Author: Samper E
Year: 2000
Journal: EMBO Rep
Title: Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang.
Volume: 1
Issue: 3
Pages: 244-52
Publication
First Author: Busuttil RA
Year: 2008
Journal: PLoS One
Title: Effect of Ku80 deficiency on mutation frequencies and spectra at a LacZ reporter locus in mouse tissues and cells.
Volume: 3
Issue: 10
Pages: e3458
Publication
First Author: Tseng SH
Year: 2015
Journal: Int J Cancer
Title: K14-EGFP-miR-31 transgenic mice have high susceptibility to chemical-induced squamous cell tumorigenesis that is associating with Ku80 repression.
Volume: 136
Issue: 6
Pages: 1263-75
Publication  
First Author: Li H
Year: 2013
Journal: Mutat Res
Title: Ku80-deleted cells are defective at base excision repair.
Volume: 745-746
Pages: 16-25
GXD Expression  
Probe: MGI:7579179
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579185
Age: embryonic day 18.5
Note: Expression co-localized with Cyp11a1 in cerebral cortex.
Specimen Label: Ku p86 E18.5 not shown
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1004670
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829246
Age: embryonic day 14.5
Image: euxassay_009101_11
Specimen Label: euxassay_009101_11
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1004670
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829246
Age: embryonic day 14.5
Image: euxassay_009101_12
Specimen Label: euxassay_009101_12
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1004670
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829246
Age: embryonic day 14.5
Image: euxassay_009101_13
Specimen Label: euxassay_009101_13
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1004670
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829246
Age: embryonic day 14.5
Image: euxassay_009101_14
Specimen Label: euxassay_009101_14
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1004670
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4829246
Age: embryonic day 14.5
Image: euxassay_009101_15
Specimen Label: euxassay_009101_15
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:7579179
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3595826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7579185
Age: embryonic day 18.5
Note: Expression co-localized with Cyp11a1 in submucosa of nasal cavity. Expression only in glandular submucosal cells.
Specimen Label: 3A Ku p86 Nasal Epithelium
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7579179
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579185
Age: embryonic day 18.5
Note: Expression co-localized with Cyp11a1 in Purkinje cell layer.
Specimen Label: 3A Ku p86 Cerebellum
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7579179
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1924126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579185
Age: embryonic day 18.5
Note: Expression co-localized with Cyp11a1 in nucleus in position of inferior olive in basal plate of hindbrain (medulla).
Specimen Label: 3A Ku p86 Hindbrain
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1004670
Assay Type: RNA in situ
Annotation Date: 2023-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7522864
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7579179
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7579185
Age: embryonic day 18.5
Note: Expression co-localized with Cyp11a1 in region of differentiating field of olfactory bulb.
Specimen Label: 3A Ku p86 Olfactory Bulb
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7579179
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7579185
Age: embryonic day 18.5
Note: Expression co-localized with Cyp11a1 in motor neurons in spinal cord.
Specimen Label: Ku p86 E18.5 not shown
Detected: true
Specimen Num: 5
Publication
First Author: Porges AJ
Year: 1990
Journal: J Immunol
Title: Antigenic determinants of the Ku (p70/p80) autoantigen are poorly conserved between species.
Volume: 145
Issue: 12
Pages: 4222-8
Publication
First Author: Falzon M
Year: 1992
Journal: Nucleic Acids Res
Title: The nucleotide sequence of a mouse cDNA encoding the 80 kDa subunit of the Ku (p70/p80) autoantigen.
Volume: 20
Issue: 14
Pages: 3784
Publication      
First Author: Zapater LJ
Year: 2023
Journal: bioRxiv
Title: A transposase-derived gene required for human brain development.
Publication
First Author: Li H
Year: 2007
Journal: Mol Cell Biol
Title: Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer.
Volume: 27
Issue: 23
Pages: 8205-14
Publication
First Author: Ouyang H
Year: 1997
Journal: J Exp Med
Title: Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.
Volume: 186
Issue: 6
Pages: 921-9
Publication
First Author: Hurd YL
Year: 1999
Journal: Mol Cell Neurosci
Title: A novel neuron-specific DNA end-binding factor in the murine brain.
Volume: 14
Issue: 3
Pages: 213-24
Publication
First Author: Jin S
Year: 1997
Journal: EMBO J
Title: Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
Volume: 16
Issue: 22
Pages: 6874-85
Publication
First Author: Osipovich O
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Defining functional domains of Ku80: DNA end binding and survival after radiation.
Volume: 261
Issue: 3
Pages: 802-7
Publication
First Author: Tomimatsu N
Year: 2007
Journal: J Biol Chem
Title: Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.
Volume: 282
Issue: 14
Pages: 10138-45
Publication
First Author: Britton S
Year: 2013
Journal: J Cell Biol
Title: A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair.
Volume: 202
Issue: 3
Pages: 579-95
Publication
First Author: Reliene R
Year: 2004
Journal: DNA Repair (Amst)
Title: Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice.
Volume: 3
Issue: 2
Pages: 103-11
Publication
First Author: Karanjawala ZE
Year: 2002
Journal: DNA Repair (Amst)
Title: The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants.
Volume: 1
Issue: 12
Pages: 1017-26
Publication
First Author: Karanjawala ZE
Year: 1999
Journal: Curr Biol
Title: The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts.
Volume: 9
Issue: 24
Pages: 1501-4
Publication
First Author: Tong WM
Year: 2002
Journal: Cancer Res
Title: Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation.
Volume: 62
Issue: 23
Pages: 6990-6
Publication
First Author: Henrie MS
Year: 2003
Journal: DNA Repair (Amst)
Title: Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis.
Volume: 2
Issue: 2
Pages: 151-8
Publication
First Author: Rossi DJ
Year: 2007
Journal: Nature
Title: Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Volume: 447
Issue: 7145
Pages: 725-9
Publication
First Author: Reliene R
Year: 2006
Journal: DNA Repair (Amst)
Title: Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine.
Volume: 5
Issue: 11
Pages: 1392-7
Publication
First Author: Holcomb VB
Year: 2007
Journal: Mech Ageing Dev
Title: Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs.
Volume: 128
Issue: 11-12
Pages: 601-8
Publication
First Author: Boon RA
Year: 2013
Journal: Nature
Title: MicroRNA-34a regulates cardiac ageing and function.
Volume: 495
Issue: 7439
Pages: 107-10
Publication
First Author: Reiling E
Year: 2014
Journal: PLoS One
Title: The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency.
Volume: 9
Issue: 4
Pages: e93568
Publication
First Author: Franco S
Year: 2005
Journal: Carcinogenesis
Title: Effectors of mammalian telomere dysfunction: a comparative transcriptome analysis using mouse models.
Volume: 26
Issue: 9
Pages: 1613-26
Publication
First Author: Couëdel C
Year: 2004
Journal: Genes Dev
Title: Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells.
Volume: 18
Issue: 11
Pages: 1293-304
Publication
First Author: Müller B
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Characterization of Double-Strand Break Repair Protein Ku80 Location Within the Murine Retina.
Volume: 63
Issue: 6
Pages: 22
Publication
First Author: Goytisolo FA
Year: 2001
Journal: Mol Cell Biol
Title: The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.
Volume: 21
Issue: 11
Pages: 3642-51
Publication
First Author: Guirouilh-Barbat J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends.
Volume: 104
Issue: 52
Pages: 20902-7
Publication
First Author: Malyarchuk S
Year: 2008
Journal: Nucleic Acids Res
Title: DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining.
Volume: 36
Issue: 15
Pages: 4872-82
Publication
First Author: Schulte-Uentrop L
Year: 2008
Journal: Nucleic Acids Res
Title: Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks.
Volume: 36
Issue: 8
Pages: 2561-9
Publication
First Author: Barnes DE
Year: 1998
Journal: Curr Biol
Title: Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice.
Volume: 8
Issue: 25
Pages: 1395-8
Publication
First Author: d'Adda di Fagagna F
Year: 2001
Journal: Curr Biol
Title: Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.
Volume: 11
Issue: 15
Pages: 1192-6
Publication
First Author: Reina-San-Martin B
Year: 2003
Journal: J Exp Med
Title: H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation.
Volume: 197
Issue: 12
Pages: 1767-78
Publication
First Author: Reina-San-Martin B
Year: 2004
Journal: J Exp Med
Title: ATM is required for efficient recombination between immunoglobulin switch regions.
Volume: 200
Issue: 9
Pages: 1103-10
Publication
First Author: Katz DJ
Year: 2005
Journal: Mol Cell Biol
Title: Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region.
Volume: 25
Issue: 10
Pages: 3855-63
Publication
First Author: Choi YJ
Year: 2014
Journal: PLoS One
Title: Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair.
Volume: 9
Issue: 1
Pages: e86358
Publication
First Author: Li H
Year: 2009
Journal: Oncogene
Title: Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells.
Volume: 28
Issue: 16
Pages: 1875-8
Publication
First Author: Holcomb VB
Year: 2008
Journal: Cancer Res
Title: Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response.
Volume: 68
Issue: 22
Pages: 9497-502
Publication
First Author: Ahmad A
Year: 2008
Journal: Mol Cell Biol
Title: ERCC1-XPF endonuclease facilitates DNA double-strand break repair.
Volume: 28
Issue: 16
Pages: 5082-92
Publication
First Author: Lim DS
Year: 2000
Journal: Mol Cell Biol
Title: Analysis of ku80-mutant mice and cells with deficient levels of p53.
Volume: 20
Issue: 11
Pages: 3772-80
Publication
First Author: Didier N
Year: 2012
Journal: EMBO Mol Med
Title: Loss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscle.
Volume: 4
Issue: 9
Pages: 910-23