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Search results 1 to 100 out of 180 for Zc3h12a

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Matsushita K
Year: 2009
Journal: Nature
Title: Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.
Volume: 458
Issue: 7242
Pages: 1185-90
Publication
First Author: Niu J
Year: 2011
Journal: J Mol Cell Cardiol
Title: MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-кB activation via inhibition of IкB kinase activation.
Volume: 51
Issue: 2
Pages: 177-86
Publication
First Author: Uehata T
Year: 2013
Journal: Cell
Title: Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation.
Volume: 153
Issue: 5
Pages: 1036-49
Publication
First Author: Qi D
Year: 2011
Journal: J Biol Chem
Title: Monocyte chemotactic protein-induced protein 1 (MCPIP1) suppresses stress granule formation and determines apoptosis under stress.
Volume: 286
Issue: 48
Pages: 41692-700
Publication
First Author: Li M
Year: 2012
Journal: PLoS One
Title: MCPIP1 down-regulates IL-2 expression through an ARE-independent pathway.
Volume: 7
Issue: 11
Pages: e49841
Publication
First Author: Younce C
Year: 2012
Journal: Cell Physiol Biochem
Title: MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy.
Volume: 30
Issue: 2
Pages: 307-20
Publication
First Author: Zhou L
Year: 2006
Journal: Circ Res
Title: Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction.
Volume: 98
Issue: 9
Pages: 1177-85
Publication
First Author: Younce CW
Year: 2009
Journal: J Biol Chem
Title: MCP-1 (monocyte chemotactic protein-1)-induced protein, a recently identified zinc finger protein, induces adipogenesis in 3T3-L1 pre-adipocytes without peroxisome proliferator-activated receptor gamma.
Volume: 284
Issue: 40
Pages: 27620-8
Publication
First Author: Garg AV
Year: 2015
Journal: Immunity
Title: MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.
Volume: 43
Issue: 3
Pages: 475-87
Publication
First Author: Liang J
Year: 2008
Journal: PLoS One
Title: Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.
Volume: 3
Issue: 8
Pages: e2880
Publication
First Author: Kapoor N
Year: 2015
Journal: J Immunol
Title: Transcription factors STAT6 and KLF4 implement macrophage polarization via the dual catalytic powers of MCPIP.
Volume: 194
Issue: 12
Pages: 6011-23
Publication
First Author: Liang J
Year: 2010
Journal: J Exp Med
Title: MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling.
Volume: 207
Issue: 13
Pages: 2959-73
Publication
First Author: Mino T
Year: 2015
Journal: Cell
Title: Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms.
Volume: 161
Issue: 5
Pages: 1058-1073
Publication
First Author: Huang S
Year: 2015
Journal: J Biol Chem
Title: Monocyte Chemotactic Protein-induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation.
Volume: 290
Issue: 34
Pages: 20782-92
Publication
First Author: Liang J
Year: 2008
Journal: J Biol Chem
Title: A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.
Volume: 283
Issue: 10
Pages: 6337-46
Publication
First Author: Niu J
Year: 2015
Journal: Basic Res Cardiol
Title: MCP-1-induced protein attenuates post-infarct cardiac remodeling and dysfunction through mitigating NF-κB activation and suppressing inflammation-associated microRNA expression.
Volume: 110
Issue: 3
Pages: 26
Publication
First Author: Iwasaki H
Year: 2011
Journal: Nat Immunol
Title: The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1.
Volume: 12
Issue: 12
Pages: 1167-75
Publication
First Author: Jeltsch KM
Year: 2014
Journal: Nat Immunol
Title: Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.
Volume: 15
Issue: 11
Pages: 1079-89
Publication
First Author: Tanaka H
Year: 2019
Journal: J Exp Med
Title: Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response.
Volume: 216
Issue: 6
Pages: 1431-1449
Publication
First Author: Lin CC
Year: 2021
Journal: Nat Commun
Title: Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation.
Volume: 12
Issue: 1
Pages: 3878
Publication
First Author: Konieczny P
Year: 2019
Journal: J Mol Med (Berl)
Title: Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation.
Volume: 97
Issue: 12
Pages: 1669-1684
Publication  
First Author: Jin Z
Year: 2019
Journal: Int J Mol Sci
Title: Essential Role of Endothelial MCPIP in Vascular Integrity and Post-Ischemic Remodeling.
Volume: 20
Issue: 1
Publication
First Author: Peng H
Year: 2018
Journal: J Allergy Clin Immunol
Title: Monocyte chemotactic protein-induced protein 1 controls allergic airway inflammation by suppressing IL-5-producing TH2 cells through the Notch/Gata3 pathway.
Volume: 142
Issue: 2
Pages: 582-594.e10
Publication
First Author: Lipert B
Year: 2014
Journal: Biochim Biophys Acta
Title: Monocyte chemoattractant protein-induced protein 1 impairs adipogenesis in 3T3-L1 cells.
Volume: 1843
Issue: 4
Pages: 780-8
Publication
First Author: Kotlinowski J
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Deletion of Mcpip1 in Mcpip1fl/flAlbCre mice recapitulates the phenotype of human primary biliary cholangitis.
Volume: 1867
Issue: 5
Pages: 166086
UniProt Feature
Begin: 1
Description: Endoribonuclease ZC3H12A
Type: chain
End: 596
Publication
First Author: Ruiz-Romeu E
Year: 2016
Journal: J Invest Dermatol
Title: MCPIP1 RNase Is Aberrantly Distributed in Psoriatic Epidermis and Rapidly Induced by IL-17A.
Volume: 136
Issue: 8
Pages: 1599-607
Publication
First Author: Yaku A
Year: 2022
Journal: Circulation
Title: Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages.
Volume: 146
Issue: 13
Pages: 1006-1022
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Yokogawa M
Year: 2016
Journal: Sci Rep
Title: Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions.
Volume: 6
Pages: 22324
Publication
First Author: Gasiorek A
Year: 2021
Journal: mBio
Title: Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts.
Volume: 12
Issue: 3
Pages: e0050221
Publication
First Author: Yang JI
Year: 2021
Journal: Arthritis Res Ther
Title: Upregulated endonuclease Regnase-1 suppresses osteoarthritis by forming a negative feedback loop of catabolic signaling in chondrocytes.
Volume: 23
Issue: 1
Pages: 114
Publication
First Author: Huang S
Year: 2013
Journal: Cell Signal
Title: MCPIP1 negatively regulates toll-like receptor 4 signaling and protects mice from LPS-induced septic shock.
Volume: 25
Issue: 5
Pages: 1228-34
Publication  
First Author: Jin Z
Year: 2013
Journal: J Neuroinflammation
Title: Delayed brain ischemia tolerance induced by electroacupuncture pretreatment is mediated via MCP-induced protein 1.
Volume: 10
Pages: 63
Publication  
First Author: Jin Z
Year: 2019
Journal: Int J Mol Sci
Title: Absence of MCP-induced Protein 1 Enhances Blood-Brain Barrier Breakdown after Experimental Stroke in Mice.
Volume: 20
Issue: 13
Publication  
First Author: Liang J
Year: 2011
Journal: J Neuroinflammation
Title: Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines.
Volume: 8
Pages: 182
Publication  
First Author: Jin Z
Year: 2015
Journal: J Neuroinflammation
Title: MCP-induced protein 1 mediates the minocycline-induced neuroprotection against cerebral ischemia/reperfusion injury in vitro and in vivo.
Volume: 12
Pages: 39
Publication
First Author: Zhou Z
Year: 2013
Journal: PLoS One
Title: MCPIP1 deficiency in mice results in severe anemia related to autoimmune mechanisms.
Volume: 8
Issue: 12
Pages: e82542
Publication
First Author: Miao R
Year: 2013
Journal: Immunol Cell Biol
Title: Targeted disruption of MCPIP1/Zc3h12a results in fatal inflammatory disease.
Volume: 91
Issue: 5
Pages: 368-76
Publication
First Author: Suzuki HI
Year: 2011
Journal: Mol Cell
Title: MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.
Volume: 44
Issue: 3
Pages: 424-36
Publication
First Author: Xu J
Year: 2012
Journal: Nucleic Acids Res
Title: Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase.
Volume: 40
Issue: 14
Pages: 6957-65
Publication
First Author: He M
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial dysfunction in rheumatoid arthritis: the role of monocyte chemotactic protein-1-induced protein.
Volume: 33
Issue: 6
Pages: 1384-91
Publication
First Author: Wei J
Year: 2019
Journal: Nature
Title: Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.
Volume: 576
Issue: 7787
Pages: 471-476
Publication
First Author: Losko M
Year: 2020
Journal: Cell Mol Life Sci
Title: Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism.
Volume: 77
Issue: 23
Pages: 4899-4919
Publication  
First Author: Li M
Year: 2020
Journal: Antiviral Res
Title: MCPIP1 inhibits Hepatitis B virus replication by destabilizing viral RNA and negatively regulates the virus-induced innate inflammatory responses.
Volume: 174
Pages: 104705
Publication  
First Author: Dobosz E
Year: 2021
Journal: Dis Model Mech
Title: Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation.
Volume: 14
Issue: 3
Publication  
First Author: Kong G
Year: 2021
Journal: Front Immunol
Title: Transgenic Expression of a Mutant Ribonuclease Regnase-1 in T Cells Disturbs T Cell Development and Functions.
Volume: 12
Pages: 682220
Publication  
First Author: Bhat N
Year: 2021
Journal: J Exp Med
Title: Regnase-1 is essential for B cell homeostasis to prevent immunopathology.
Volume: 218
Issue: 5
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1A E12
Specimen Label: 1A E12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7567772
Age: embryonic day 13.0
Image: 1A E13
Specimen Label: 1A E13
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7567772
Age: embryonic day 18.0
Image: 1A E18
Specimen Label: 1A E18
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7567772
Age: embryonic day 16.0
Image: 1A E16
Specimen Label: 1A E16
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1A E12
Specimen Label: 1A E12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7567772
Age: embryonic day 13.0
Image: 1A E13
Specimen Label: 1A E13
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7567772
Age: embryonic day 16.0
Image: 1A E16
Specimen Label: 1A E16
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7567772
Age: embryonic day 18.0
Image: 1A E18
Note: Expression increased significantly from E12 to E18.
Specimen Label: 1A E18
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1B
Specimen Label: 1B
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1E
Note: Expression is in newborn neurons.
Specimen Label: 1E
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1F
Note: Expression is in newborn neurons.
Specimen Label: 1F
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1D
Specimen Label: 1D
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1A E12
Specimen Label: 1A E12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7567772
Age: embryonic day 13.0
Image: 1A E13
Specimen Label: 1A E13
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7567772
Age: embryonic day 16.0
Image: 1A E16
Specimen Label: 1A E16
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7567772
Age: embryonic day 18.0
Image: 1A E18
Specimen Label: 1A E18
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1A E12
Specimen Label: 1A E12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7567772
Age: embryonic day 13.0
Image: 1A E13
Specimen Label: 1A E13
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1B
Note: Expression is in early neural progenitors.
Specimen Label: 1B
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1C
Note: Expression is in early neural progenitors.
Specimen Label: 1C
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7567772
Age: embryonic day 12.0
Image: 1D
Note: Expression is in early neural progenitors.
Specimen Label: 1D
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7567772
Age: embryonic day 16.0
Image: 1A E16
Specimen Label: 1A E16
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7567425
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7567772
Age: embryonic day 18.0
Image: 1A E18
Note: Expression decreased significantly from E12 to E18.
Specimen Label: 1A E18
Detected: true
Specimen Num: 4