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Search results 1 to 100 out of 105 for Zcchc4

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
29063 | ZCCHC4
Type: gene
Organism: human
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Gene
511397 | ZCCHC4
Type: gene
Organism: cattle
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Gene
422806 | ZCCHC4
Type: gene
Organism: chicken
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Gene
564410 | zcchc4
Type: gene
Organism: zebrafish
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Gene
693685 | ZCCHC4
Type: gene
Organism: macaque, rhesus
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Gene
493496 | zcchc4
Type: gene
Organism: frog, western clawed
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Gene
360946 | Zcchc4
Type: gene
Organism: rat
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Gene
479125 | ZCCHC4
Type: gene
Organism: dog, domestic
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Gene
461147 | ZCCHC4
Type: gene
Organism: chimpanzee
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Protein Domain
IPR039846 | ZCCHC4
Type: Family
Description: ZCCHC4 is an rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA []. N6-methylation of adenine(4220) in 28S rRNA is required for translation [].
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Protein Coding Gene
MGI:1926046 | Zcchc4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q08EK6
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: false
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Protein
A0A0G2JEN2
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
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Protein
Q8BKW4
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
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Publication
30531910 | -
First Author: Ma H
Year: 2019
Journal: Nat Chem Biol
Title: N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.
Volume: 15
Issue: 1
Pages: 88-94
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Protein Coding Gene
MGP_CAROLIEiJ_G0027220 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029517 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029526 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1926046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029324 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028381 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017002 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028215 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3615233
Assay Type: RT-PCR
Annotation Date: 2006-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616866
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3615233
Assay Type: RT-PCR
Annotation Date: 2006-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616866
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Note: Expression was detected in precortical tissue.
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617768
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3616013
Assay Type: RNA in situ
Annotation Date: 2006-03-27
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617768
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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Publication
24105743 | J:202816
First Author: Wajapeyee N
Year: 2013
Journal: Genes Dev
Title: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.
Volume: 27
Issue: 20
Pages: 2221-6
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31799605 | J:285175
First Author: Pinto R
Year: 2020
Journal: Nucleic Acids Res
Title: The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.
Volume: 48
Issue: 2
Pages: 830-846
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UniProt Feature
UniProt Feature
Begin: 1
Description: rRNA N6-adenosine-methyltransferase ZCCHC4
Type: chain
End: 512
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Protein
Q8BKW4-2
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
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Allele
Zcchc4<tm1Smoc> | MGI:7293229
Name: zinc finger, CCHC domain containing 4; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6429818 | C57BL/6J-Zcchc4<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
16479578 | -
First Author: Ratel D
Year: 2006
Journal: Bioessays
Title: N6-methyladenine: the other methylated base of DNA.
Volume: 28
Issue: 3
Pages: 309-15
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Protein Domain
IPR041370 | Mlase_EEF1AKMT1/ZCCHC4
Type: Family
Description: This is a protein of approximately 200 residues which is conserved from plants to humans []. It contains a highly conserved QFW motif close to the N terminus and a DPPF motif in the centre. The DPPF motif is characteristic of N-6 adenine-specific DNA methylases, and this family is found in eukaryotes []. Proteins in this entry include EEF1A lysine methyltransferase 1 (EEF1AKMT1) and ZCCHC4. EEF1AKMT1 is a protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79' []. ZCCHC4 is an rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA [].
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Publication
26545399 | -
First Author: Hamey JJ
Year: 2016
Journal: Mol Cell Proteomics
Title: Novel N-terminal and Lysine Methyltransferases That Target Translation Elongation Factor 1A in Yeast and Human.
Volume: 15
Issue: 1
Pages: 164-76
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Publication
35033535 | J:322368
First Author: Sepich-Poore C
Year: 2022
Journal: J Biol Chem
Title: The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation.
Volume: 298
Issue: 3
Pages: 101590
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