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Search results 1 to 100 out of 121 for Zmpste24

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Fu B
Year: 2017
Journal: J Exp Med
Title: ZMPSTE24 defends against influenza and other pathogenic viruses.
Volume: 214
Issue: 4
Pages: 919-929
Publication
First Author: Pendás AM
Year: 2002
Journal: Nat Genet
Title: Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.
Volume: 31
Issue: 1
Pages: 94-9
Publication
First Author: Calyeca J
Year: 2018
Journal: Aging (Albany NY)
Title: Accelerated aging induced by deficiency of Zmpste24 protects old mice to develop bleomycin-induced pulmonary fibrosis.
Volume: 10
Issue: 12
Pages: 3881-3896
Publication
First Author: Osorio FG
Year: 2010
Journal: Aging Cell
Title: Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.
Volume: 9
Issue: 6
Pages: 947-57
Publication
First Author: Yao H
Year: 2020
Journal: Aging Cell
Title: Targeting RAS-converting enzyme 1 overcomes senescence and improves progeria-like phenotypes of ZMPSTE24 deficiency.
Volume: 19
Issue: 8
Pages: e13200
Publication
First Author: Shilagardi K
Year: 2022
Journal: mBio
Title: The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation.
Volume: 13
Issue: 5
Pages: e0254322
Publication
First Author: Heizer PJ
Year: 2020
Journal: J Lipid Res
Title: Deficiency in ZMPSTE24 and resulting farnesyl-prelamin A accumulation only modestly affect mouse adipose tissue stores.
Volume: 61
Issue: 3
Pages: 413-421
Publication
First Author: Varela I
Year: 2005
Journal: Nature
Title: Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.
Volume: 437
Issue: 7058
Pages: 564-8
Publication
First Author: Greising SM
Year: 2012
Journal: Age (Dordr)
Title: Skeletal muscle contractile function and neuromuscular performance in Zmpste24 -/- mice, a murine model of human progeria.
Volume: 34
Issue: 4
Pages: 805-19
Publication
First Author: Bergo MO
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.
Volume: 99
Issue: 20
Pages: 13049-54
Publication  
First Author: Wang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice.
Volume: 119
Issue: 9
Publication
First Author: Coffinier C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.
Volume: 104
Issue: 33
Pages: 13432-7
Publication
First Author: Mariño G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.
Volume: 107
Issue: 37
Pages: 16268-73
Publication
First Author: Leung GK
Year: 2001
Journal: J Biol Chem
Title: Biochemical studies of Zmpste24-deficient mice.
Volume: 276
Issue: 31
Pages: 29051-8
Publication
First Author: Chang SY
Year: 2012
Journal: J Lipid Res
Title: Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24.
Volume: 53
Issue: 6
Pages: 1176-82
Publication
First Author: Mateos J
Year: 2018
Journal: PLoS One
Title: Next-Generation Sequencing and Quantitative Proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging.
Volume: 13
Issue: 10
Pages: e0205878
Publication
First Author: Fong LG
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice.
Volume: 101
Issue: 52
Pages: 18111-6
Publication
First Author: Krishnan V
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice.
Volume: 108
Issue: 30
Pages: 12325-30
Publication
First Author: Whitton H
Year: 2018
Journal: Aging Cell
Title: Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver.
Volume: 17
Issue: 3
Pages: e12742
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Fong LG
Year: 2006
Journal: Science
Title: A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.
Volume: 311
Issue: 5767
Pages: 1621-3
Publication      
First Author: Mu X
Year: 2020
Journal: Aging Cell
Title: Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson-Gilford Progeria Syndrome.
Publication
First Author: Griveau A
Year: 2020
Journal: Aging Cell
Title: The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes.
Volume: 19
Issue: 4
Pages: e13122
Publication
First Author: Choi JY
Year: 2018
Journal: J Bone Miner Res
Title: Diminished Canonical β-Catenin Signaling During Osteoblast Differentiation Contributes to Osteopenia in Progeria.
Volume: 33
Issue: 11
Pages: 2059-2070
Publication  
First Author: Chae JB
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Accelerated aging phenotypes in the retinal pigment epithelium of Zmpste24-deficient mice.
Volume: 632
Pages: 62-68
Publication
First Author: Varela I
Year: 2008
Journal: Nat Med
Title: Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.
Volume: 14
Issue: 7
Pages: 767-72
GXD Expression        
Probe: MGI:2679815
Assay Type: RT-PCR
Annotation Date: 2003-11-24
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2679825
Age: postnatal
Specimen Label: Oocyte
Specimen Num: 1
GXD Expression      
Probe: MGI:2679815
Assay Type: RT-PCR
Annotation Date: 2003-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:2679825
Age: embryonic day 2.5
Specimen Label: 8-Cell
Detected: true
Specimen Num: 2
Publication
First Author: Griveau A
Year: 2018
Journal: Aging Cell
Title: Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
Volume: 17
Issue: 6
Pages: e12835
Publication
First Author: Zhang L
Year: 2021
Journal: Aging Cell
Title: Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging.
Volume: 20
Issue: 12
Pages: e13486
Publication
First Author: Wang M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.
Volume: 478
Issue: 2
Pages: 1006-13
Publication
First Author: Fei D
Year: 2019
Journal: Aging Cell
Title: Cav 1.2 regulates osteogenesis of bone marrow-derived mesenchymal stem cells via canonical Wnt pathway in age-related osteoporosis.
Volume: 18
Issue: 4
Pages: e12967
Publication
First Author: Rivera-Torres J
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.
Volume: 113
Issue: 46
Pages: E7250-E7259
Publication    
First Author: Qian M
Year: 2018
Journal: Elife
Title: Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.
Volume: 7
Publication  
First Author: Kim PH
Year: 2018
Journal: Sci Transl Med
Title: Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 10
Issue: 460
Publication
First Author: Fong LG
Year: 2006
Journal: J Clin Invest
Title: Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
Volume: 116
Issue: 3
Pages: 743-52
Publication
First Author: Coffinier C
Year: 2010
Journal: J Biol Chem
Title: Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.
Volume: 285
Issue: 27
Pages: 20818-26
Publication
First Author: Zhang H
Year: 2013
Journal: Aging Cell
Title: Mouse models of laminopathies.
Volume: 12
Issue: 1
Pages: 2-10
Publication
First Author: Davies BS
Year: 2010
Journal: Hum Mol Genet
Title: An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.
Volume: 19
Issue: 13
Pages: 2682-94
Publication
First Author: Yang SH
Year: 2015
Journal: Hum Mol Genet
Title: Mice that express farnesylated versions of prelamin A in neurons develop achalasia.
Volume: 24
Issue: 10
Pages: 2826-40
Publication
First Author: Bárcena C
Year: 2018
Journal: Cell Rep
Title: Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.
Volume: 24
Issue: 9
Pages: 2392-2403
Publication
First Author: Bárcena C
Year: 2019
Journal: Nat Med
Title: Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.
Volume: 25
Issue: 8
Pages: 1234-1242
Publication
First Author: Liu B
Year: 2005
Journal: Nat Med
Title: Genomic instability in laminopathy-based premature aging.
Volume: 11
Issue: 7
Pages: 780-5
Publication
First Author: Ao Y
Year: 2019
Journal: Sci Adv
Title: Lamin A buffers CK2 kinase activity to modulate aging in a progeria mouse model.
Volume: 5
Issue: 3
Pages: eaav5078
Publication  
First Author: Liu B
Year: 2013
Journal: Nat Commun
Title: Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.
Volume: 4
Pages: 1868
Publication
First Author: Liu M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer.
Volume: 107
Issue: 14
Pages: 6471-6
Publication  
First Author: Levy Y
Year: 2018
Journal: JCI Insight
Title: Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness.
Volume: 3
Issue: 19
Publication
First Author: Ibrahim MX
Year: 2013
Journal: Science
Title: Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
Volume: 340
Issue: 6138
Pages: 1330-3
Publication      
First Author: Bae JH
Year: 2020
Journal: J Cachexia Sarcopenia Muscle
Title: Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration.
Publication
First Author: Jung HJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.
Volume: 109
Issue: 7
Pages: E423-31
Publication
First Author: Christiansen JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments.
Volume: 108
Issue: 21
Pages: 8862-6
Publication
First Author: Osorio FG
Year: 2012
Journal: Genes Dev
Title: Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response.
Volume: 26
Issue: 20
Pages: 2311-24
Publication
First Author: Liu B
Year: 2012
Journal: Cell Metab
Title: Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria.
Volume: 16
Issue: 6
Pages: 738-50
Publication
First Author: Zeng F
Year: 2003
Journal: Biol Reprod
Title: Gene expression in mouse oocytes and preimplantation embryos: use of suppression subtractive hybridization to identify oocyte- and embryo-specific genes.
Volume: 68
Issue: 1
Pages: 31-9
Publication
First Author: Di Micco A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Volume: 113
Issue: 32
Pages: E4671-80
Publication
First Author: Mariño G
Year: 2008
Journal: Hum Mol Genet
Title: Premature aging in mice activates a systemic metabolic response involving autophagy induction.
Volume: 17
Issue: 14
Pages: 2196-211
Publication
First Author: Ugalde AP
Year: 2011
Journal: EMBO J
Title: Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.
Volume: 30
Issue: 11
Pages: 2219-32
Publication
First Author: Lee R
Year: 2010
Journal: Hum Mol Genet
Title: Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.
Volume: 19
Issue: 8
Pages: 1603-17
Publication
First Author: Fouillade C
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.
Volume: 33
Issue: 1
Pages: 76-86
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms