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Search results 1 to 100 out of 418 for Zp3

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Type Details Score
Gene
key_980147 | Zp3
Type: gene
Organism: Not Specified
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Gene
7784 | ZP3
Type: gene
Organism: human
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Gene
280964 | ZP3
Type: gene
Organism: cattle
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Gene
378906 | ZP3
Type: gene
Organism: chicken
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Gene
30594 | zp3
Type: gene
Organism: zebrafish
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Gene
719925 | ZP3
Type: gene
Organism: macaque, rhesus
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Gene
394444 | zp3
Type: gene
Organism: frog, western clawed
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Gene
100135322 | zp3
Type: gene
Organism: frog, western clawed
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Gene
114639 | Zp3
Type: gene
Organism: rat
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Gene
403894 | ZP3
Type: gene
Organism: dog, domestic
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Gene
472662 | ZP3
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:99215 | Zp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR040196 | ZP3
Type: Family
Description: At fertilization, mammalian sperm binds to the extracellular zona pellucida that surrounds ovulated eggs. The zona pellucida is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4 []. Fish eggs are also surrounded by an envelope, which consists of a few proteins homologous to mammalian ZP1, ZP3, and ZP4 [, ]. Glycoprotein ZP3 is essential for normal fertility []. It promotes fertilization by recognizing sperm binding and activating the acrosome reaction [, ]. It is also required for germinal vesicle breakdown in oocyte meiosis [].
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Publication
10603086 | J:59198
First Author: Del Giacco L
Year: 2000
Journal: Dev Genes Evol
Title: Identification and spatial distribution of the mRNA encoding an egg envelope component of the Cyprinid zebrafish, Danio rerio, homologous to the mammalian ZP3 (ZPC).
Volume: 210
Issue: 1
Pages: 41-6
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Gene
100421623 | ZP3P1
Type: gene
Organism: human
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Gene
100421642 | ZP3P2
Type: gene
Organism: human
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Publication
9609824 | J:77459
First Author: Rankin TL
Year: 1998
Journal: Development
Title: Human ZP3 restores fertility in Zp3 null mice without affecting order-specific sperm binding.
Volume: 125
Issue: 13
Pages: 2415-24
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Gene
22932 | POMZP3
Type: gene
Organism: human
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Publication
28145526 | -
 
First Author: Gao LL
Year: 2017
Journal: Sci Rep
Title: ZP3 is Required for Germinal Vesicle Breakdown in Mouse Oocyte Meiosis.
Volume: 7
Pages: 41272
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Publication
28886344 | -
First Author: Chen T
Year: 2017
Journal: Am J Hum Genet
Title: A Recurrent Missense Mutation in ZP3 Causes Empty Follicle Syndrome and Female Infertility.
Volume: 101
Issue: 3
Pages: 459-465
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Publication
2986849 | -
First Author: Florman HM
Year: 1985
Journal: Cell
Title: O-linked oligosaccharides of mouse egg ZP3 account for its sperm receptor activity.
Volume: 41
Issue: 1
Pages: 313-24
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Publication
2544604 | -
First Author: Leyton L
Year: 1989
Journal: J Cell Biol
Title: Evidence that aggregation of mouse sperm receptors by ZP3 triggers the acrosome reaction.
Volume: 108
Issue: 6
Pages: 2163-8
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Publication
14645511 | J:86870
First Author: Zhao M
Year: 2003
Journal: Mol Cell Biol
Title: Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs.
Volume: 23
Issue: 24
Pages: 8982-91
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Publication
17047254 | J:114998
First Author: Hoodbhoy T
Year: 2006
Journal: Mol Cell Biol
Title: ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida.
Volume: 26
Issue: 21
Pages: 7991-8
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Publication
18420282 | J:169882
First Author: Borillo J
Year: 2008
Journal: J Reprod Immunol
Title: Antibodies to two ZP3 B cell epitopes affect zona pellucida assembly.
Volume: 78
Issue: 2
Pages: 149-57
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Publication
1577197 | J:760
First Author: Beebe SJ
Year: 1992
Journal: Dev Biol
Title: Recombinant mouse ZP3 inhibits sperm binding and induces the acrosome reaction.
Volume: 151
Issue: 1
Pages: 48-54
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Publication
17258189 | J:169895
First Author: Jungnickel MK
Year: 2007
Journal: Dev Biol
Title: Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction.
Volume: 304
Issue: 1
Pages: 116-26
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Publication
7873981 | J:22342
First Author: Kimura J
Year: 1994
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Localization of ZP3 mRNA in mouse ovary by non-radioactive in situ hybridization with digoxigenin-labelled cDNA.
Volume: 40
Issue: 8
Pages: 1097-101
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Publication
28646452 | J:302592
First Author: Liu W
Year: 2017
Journal: Hum Genet
Title: Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility.
Volume: 136
Issue: 8
Pages: 975-985
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Publication
11940668 | J:78932
First Author: Zhao M
Year: 2002
Journal: Mol Cell Biol
Title: Conserved furin cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice.
Volume: 22
Issue: 9
Pages: 3111-20
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Publication
19052627 | J:169986
First Author: Monné M
Year: 2008
Journal: Nature
Title: Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats.
Volume: 456
Issue: 7222
Pages: 653-7
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Publication
7816829 | J:22288
First Author: Kinloch RA
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Mapping the mouse ZP3 combining site for sperm by exon swapping and site-directed mutagenesis.
Volume: 92
Issue: 1
Pages: 263-7
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Publication
21378311 | J:182980
First Author: Jimenez-Movilla M
Year: 2011
Journal: J Cell Sci
Title: ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida.
Volume: 124
Issue: Pt 6
Pages: 940-50
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Publication
8787763 | J:36772
First Author: Rankin T
Year: 1996
Journal: Development
Title: Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile.
Volume: 122
Issue: 9
Pages: 2903-10
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Publication
10793136 | J:169811
First Author: O'Toole CM
Year: 2000
Journal: Mol Biol Cell
Title: Ca(2+) entry through store-operated channels in mouse sperm is initiated by egg ZP3 and drives the acrosome reaction.
Volume: 11
Issue: 5
Pages: 1571-84
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Publication
7545161 | J:28755
First Author: Thall AD
Year: 1995
Journal: J Biol Chem
Title: Oocyte Gal alpha 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse.
Volume: 270
Issue: 37
Pages: 21437-40
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Publication
11906903 | J:75669
First Author: El-Mestrah M
Year: 2002
Journal: Biol Reprod
Title: Subcellular distribution of ZP1, ZP2, and ZP3 glycoproteins during folliculogenesis and demonstration of their topographical disposition within the zona matrix of mouse ovarian oocytes.
Volume: 66
Issue: 4
Pages: 866-76
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Publication
24934154 | J:215794
First Author: Avella MA
Year: 2014
Journal: J Cell Biol
Title: A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans.
Volume: 205
Issue: 6
Pages: 801-9
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Publication
12852850 | J:93482
First Author: Rankin TL
Year: 2003
Journal: Dev Cell
Title: Fertility and taxon-specific sperm binding persist after replacement of mouse sperm receptors with human homologs.
Volume: 5
Issue: 1
Pages: 33-43
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Protein
Q8VHA3
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
F6VD35
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Protein
Q8VHA4
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
Q8VHA1
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
Q8VHA2
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Publication
29853180 | -
 
First Author: Litscher ES
Year: 2018
Journal: Curr Top Dev Biol
Title: The Fish Egg's Zona Pellucida.
Volume: 130
Pages: 275-305
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Publication
25445843 | -
 
First Author: Gupta SK
Year: 2015
Journal: J Reprod Immunol
Title: Role of zona pellucida glycoproteins during fertilization in humans.
Volume: 108
Pages: 90-7
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Protein
Q8VH88
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
Q8VH89
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
Q8VH86
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
Q8VH87
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: true
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Protein
P10761
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Protein
Q3V2B5
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Publication
9002630 | J:38081
First Author: Zhang X
Year: 1997
Journal: Biol Reprod
Title: Antibody responses and infertility in mice following oral immunization with attenuated Salmonella typhimurium expressing recombinant murine ZP3.
Volume: 56
Issue: 1
Pages: 33-41
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Gene
747724 | POMZP3
Type: gene
Organism: chimpanzee
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Publication
2842770 | J:9329
First Author: Kinloch RA
Year: 1988
Journal: Proc Natl Acad Sci U S A
Title: Primary structure of the mouse sperm receptor polypeptide determined by genomic cloning.
Volume: 85
Issue: 17
Pages: 6409-13
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Publication
2884155 | J:30631
First Author: Philpott CC
Year: 1987
Journal: Dev Biol
Title: Oocyte-specific expression and developmental regulation of ZP3, the sperm receptor of the mouse zona pellucida.
Volume: 121
Issue: 2
Pages: 568-75
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Publication
8848588 | J:32055
First Author: Kolluri SK
Year: 1995
Journal: Reprod Fertil Dev
Title: Nucleotide sequence of cDNA encoding bonnet monkey (Macaca radiata) zona pellucida glycoprotein-ZP3.
Volume: 7
Issue: 5
Pages: 1209-12
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Publication
3378665 | J:9207
First Author: Ringuette MJ
Year: 1988
Journal: Dev Biol
Title: Molecular analysis of cDNA coding for ZP3, a sperm binding protein of the mouse zona pellucida.
Volume: 127
Issue: 2
Pages: 287-95
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Publication
18667753 | J:169876
First Author: O'Leary S
Year: 2008
Journal: Biol Reprod
Title: Immunization with recombinant murine cytomegalovirus expressing murine zona pellucida 3 causes permanent infertility in BALB/c mice due to follicle depletion and ovulation failure.
Volume: 79
Issue: 5
Pages: 849-60
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Publication
20382503 | J:170041
First Author: Lloyd ML
Year: 2010
Journal: J Autoimmun
Title: Immunoglobulin to zona pellucida 3 mediates ovarian damage and infertility after contraceptive vaccination in mice.
Volume: 35
Issue: 1
Pages: 77-85
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Publication
2535821 | J:9513
First Author: Chamberlin ME
Year: 1989
Journal: Dev Biol
Title: Genomic organization of a sex specific gene: the primary sperm receptor of the mouse zona pellucida.
Volume: 131
Issue: 1
Pages: 207-14
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Publication
7561067 | J:28786
First Author: Lou YH
Year: 1995
Journal: J Immunol
Title: Altered target organ. A mechanism of postrecovery resistance to murine autoimmune oophoritis.
Volume: 155
Issue: 7
Pages: 3667-73
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Publication
15579591 | J:169908
First Author: Clydesdale G
Year: 2004
Journal: Reproduction
Title: Contraception in mice immunized with recombinant zona pellucida subunit 3 proteins correlates with Th2 responses and the levels of interleukin 4 expressed by CD4+ cells.
Volume: 128
Issue: 6
Pages: 737-45
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Publication
20616279 | J:161507
First Author: Gahlay G
Year: 2010
Journal: Science
Title: Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein.
Volume: 329
Issue: 5988
Pages: 216-9
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Publication
14972104 | J:87185
First Author: Coonrod SA
Year: 2004
Journal: Reprod Fertil Dev
Title: Oocyte proteomics: localisation of mouse zona pellucida protein 3 to the plasma membrane of ovulated mouse eggs.
Volume: 16
Issue: 1-2
Pages: 69-78
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Publication
2591314 | J:289368
First Author: Roller RJ
Year: 1989
Journal: Development
Title: Gene expression during mammalian oogenesis and early embryogenesis: quantification of three messenger RNAs abundant in fully grown mouse oocytes.
Volume: 106
Issue: 2
Pages: 251-61
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Publication
7841460 | J:21969
First Author: Harris JD
Year: 1994
Journal: DNA Seq
Title: Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: the ZPA, ZPB and ZPC gene families.
Volume: 4
Issue: 6
Pages: 361-93
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Publication
7822321 | J:23006
First Author: Tong ZB
Year: 1995
Journal: J Biol Chem
Title: Inhibition of zona pellucida gene expression by antisense oligonucleotides injected into mouse oocytes.
Volume: 270
Issue: 2
Pages: 849-53
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Publication
8089187 | J:20319
First Author: Youakim A
Year: 1994
Journal: J Cell Biol
Title: Overexpressing sperm surface beta 1,4-galactosyltransferase in transgenic mice affects multiple aspects of sperm-egg interactions.
Volume: 126
Issue: 6
Pages: 1573-83
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Publication
9374408 | J:43773
First Author: Lu Q
Year: 1997
Journal: Development
Title: Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly.
Volume: 124
Issue: 20
Pages: 4121-31
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Publication
7635043 | J:26752
First Author: Epifano O
Year: 1995
Journal: Development
Title: Coordinate expression of the three zona pellucida genes during mouse oogenesis.
Volume: 121
Issue: 7
Pages: 1947-56
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Publication
10729725 | J:61584
First Author: Prasad SV
Year: 2000
Journal: Cells Tissues Organs
Title: Structure and function of the proteins of the mammalian Zona pellucida.
Volume: 166
Issue: 2
Pages: 148-64
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Publication
11023867 | J:64677
First Author: Soyal SM
Year: 2000
Journal: Development
Title: FIGalpha, a germ cell-specific transcription factor required for ovarian follicle formation.
Volume: 127
Issue: 21
Pages: 4645-54
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Publication
15970507 | J:103183
 
First Author: Naz RK
Year: 2005
Journal: Front Biosci
Title: Gene knockouts that cause female infertility: search for novel contraceptive targets.
Volume: 10
Pages: 2447-59
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Protein Coding Gene
MGP_129S1SvImJ_G0030195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030096 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029965 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029372 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024429 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028848 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2541416 | J:9774
First Author: Kinloch RA
Year: 1989
Journal: Nucleic Acids Res
Title: Nucleotide sequence of the gene encoding zona pellucida glycoprotein ZP3--the mouse sperm receptor.
Volume: 17
Issue: 7
Pages: 2861-3
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Publication
8643592 | J:33254
First Author: Liu C
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of the mZP3 gene results in production of eggs lacking a zona pellucida and infertility in female mice.
Volume: 93
Issue: 11
Pages: 5431-6
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Publication
9107049 | J:39483
First Author: Wassarman PM
Year: 1997
Journal: Proc Biol Sci
Title: Mutant female mice carrying a single mZP3 allele produce eggs with a thin zona pellucida, but reproduce normally.
Volume: 264
Issue: 1380
Pages: 323-8
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Publication
10440843 | J:57345
First Author: Qi H
Year: 1999
Journal: Dev Genet
Title: Secretion of zona pellucida glycoprotein mZP2 by growing oocytes from mZP3(+/+) and mZP3(-/-) mice.
Volume: 25
Issue: 2
Pages: 95-102
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Publication
9476659 | J:47519
First Author: Wassarman PM
Year: 1998
Journal: Histol Histopathol
Title: Ovarian development in mice bearing homozygous or heterozygous null mutations in zona pellucida glycoprotein gene mZP3.
Volume: 13
Issue: 1
Pages: 293-300
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Publication
3012564 | J:8308
First Author: Ringuette MJ
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Oocyte-specific gene expression: molecular characterization of a cDNA coding for ZP-3, the sperm receptor of the mouse zona pellucida.
Volume: 83
Issue: 12
Pages: 4341-5
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Publication
1729594 | J:2013
First Author: Schickler M
Year: 1992
Journal: Mol Cell Biol
Title: A mouse oocyte-specific protein that binds to a region of mZP3 promoter responsible for oocyte-specific mZP3 gene expression.
Volume: 12
Issue: 1
Pages: 120-7
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Publication
8305213 | J:15816
First Author: Lira SA
Year: 1993
Journal: Mol Reprod Dev
Title: cis-acting DNA elements involved in oocyte-specific expression of mouse sperm receptor gene mZP3 are located close to the gene's transcription start site.
Volume: 36
Issue: 4
Pages: 494-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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