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Search results 1 to 100 out of 140 for Zpr1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: This family consist of zinc finger protein ZPR1 and ZPR1-like proteins. The function of ZPR1 is not clear. ZPR1 is present in both the cytoplasm and nucleoplasma and its subcellular distribution changes during proliferation []. ZPR1 binds to the cytoplasmic tyrosine kinase domain of the epidermal growth factor receptor (EGFR) []and is a component of downstream signaling of both EGFR and FGFR signaling []. It has been associated with susceptibility to type 2 diabetes []and is downregulated in patients with spinal muscular atrophy [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Galcheva-Gargova Z
Year: 1996
Journal: Science
Title: Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor.
Volume: 272
Issue: 5269
Pages: 1797-802
Publication
First Author: Doran B
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of the zinc finger protein ZPR1 causes neurodegeneration.
Volume: 103
Issue: 19
Pages: 7471-5
Publication
First Author: Gangwani L
Year: 2005
Journal: Mol Cell Biol
Title: ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.
Volume: 25
Issue: 7
Pages: 2744-56
Publication
First Author: Gangwani L
Year: 1998
Journal: J Cell Biol
Title: Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.
Volume: 143
Issue: 6
Pages: 1471-84
Publication
First Author: Mishra AK
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes.
Volume: 104
Issue: 35
Pages: 13930-5
Protein
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: true
Publication
First Author: Galcheva-Gargova Z
Year: 1998
Journal: Mol Biol Cell
Title: The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells.
Volume: 9
Issue: 10
Pages: 2963-71
Publication
First Author: Ahmad S
Year: 2012
Journal: Hum Mol Genet
Title: The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy.
Volume: 21
Issue: 12
Pages: 2745-58
Publication
First Author: Ruiz OE
Year: 2012
Journal: PLoS One
Title: Drosophila Zpr1 (Zinc finger protein 1) is required downstream of both EGFR and FGFR signaling in tracheal subcellular lumen formation.
Volume: 7
Issue: 9
Pages: e45649
Publication  
First Author: Guan F
Year: 2016
Journal: Sci Rep
Title: Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.
Volume: 6
Pages: 29586
Protein
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: true
Publication
First Author: Gangwani L
Year: 2006
Journal: J Biol Chem
Title: Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progression.
Volume: 281
Issue: 52
Pages: 40330-40
Gene
Type: gene
Organism: human
Publication
First Author: Kannan A
Year: 2020
Journal: Brain
Title: ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
Volume: 143
Issue: 1
Pages: 69-93
Publication
First Author: Genabai NK
Year: 2017
Journal: Sci Rep
Title: Deregulation of ZPR1 causes respiratory failure in spinal muscular atrophy.
Volume: 7
Issue: 1
Pages: 8295
Protein
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2156726
Assay Type: Northern blot
Annotation Date: 2002-01-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156727
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509201
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539514
Age: embryonic day 15.5
Image: GUDMAP:5841
Specimen Label: GUDMAP:5841
Specimen Num: 1
GXD Expression    
Probe: MGI:3506511
Assay Type: RNA in situ
Annotation Date: 2021-03-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513968
Age: embryonic day 15.5
Note: Very weak staining was observed, indicating potential expression.
Specimen Label: Table S1 - Zfp259
Specimen Num: 1
GXD Expression    
Probe: MGI:4429098
Assay Type: RNA in situ
Annotation Date: 2024-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576704
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4429098
Assay Type: RNA in situ
Annotation Date: 2024-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576704
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Hemberger M
Year: 2000
Journal: Dev Biol
Title: cDNA subtraction cloning reveals novel genes whose temporal and spatial expression indicates association with trophoblast invasion.
Volume: 222
Issue: 1
Pages: 158-69
Publication
First Author: Horiuchi K
Year: 2018
Journal: Cell Rep
Title: Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.
Volume: 23
Issue: 1
Pages: 143-155
Publication  
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform